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Pengaruh Asam Metoksiasetat terhadap Organ Reproduksi Mencit (Mus musculus) Swiss Webster Jantan Maman Rumanta; Tien W. Surjono; Sri Sudarwati
Journal of Mathematical and Fundamental Sciences Vol. 33 No. 2 (2001)
Publisher : Institute for Research and Community Services (LPPM) ITB

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Sari. Asam metoksiasetat (MAA) merupakan salah satu metabolit dari dimetoksietil ftalat (DMEP) yaitu suatu senyawa yang banyak digunakan dalam pembuatan plastik sebagai pelentur (plasticizer). DMEP dapat luruh dari plastik dan bila masuk ke dalam tubuh manusia, zat ini diubah menjadi MAA yang dapat menyebabkan efek teratogenik dan toksik terhadap organ tubuh. Terutama organ reproduksi jantan. Untuk meneliti pengaruh MAA terhadap organ reproduksi jantan, digunakan mencit Swiss Webster umur 7 minggu, yang cliberi dosis 100, 150, 225, dan 300 mg/kg berat badan, secara gavage setiap hari selama 4 minggu berturut-turut, dengan satu hari istirahat pada tiap akhir minggu. Kelompok mencit kontrol hanya diberi akuabides sebagai pelarut MAA. Mencit dibunuh sehari setelah pemberian MAA terakhir. Pengamatan dilakukan terhadap berat testis, berat epididimis, dan berat vesikula seminalis; jumlah, motilitas, dan morfologi spermatozoa yang diperoleh dari epididimis kauda; struktur testis yang mencakup diameter, tebal epitel, dan penampilan tubulus seminiferus; jumlah sel spermatogenik, jumlah sel Sertoli, serta jumlah sel Leydig. Dibandingkan dengan kontrol, hasil pengamatan menuniukkan penurunan berat testis dan epididimis, tetapi tidak ada penurunan berat vesikula seminalis. Jumlah dan motilitas spermatozoa menjadi lebih rendah, sedangkan jumlah spermatozoa abnormal meningkat. Diameter dan tebal epitel tubulus seminiferus menurun, demikian pula persentase tubulus seminiferus normal (fase VII), sedangkan persenfase tubulus seminiferus abnormal meningkat. Pendedahan terhadap MAA menyebabkan berdegenerasinya sel-sel spermatogenik, terutama spermatosit pakhiten dans permatid, yang ditunjukkan oleh jumlahnya yang berkurang. Spermatogonium A dan spermatosit praleptoten paling tahan terhadap MAA. Jumlah sel Sertoli dan sel Leydig tidak menurun oleh perlakuan MAA meskipun tampak adanya gejala toksik pada sel Sertoli yang ditandai oleh vakuolisasi dalam sitoplasma. Dapat disimpulkan bahwa testis merupakan organ reproduksi yang paling sensitif terhadap pengaruh MAA yang mengakibatkan terganggunya spermatogenesis pada mencit Swiss Webster. Effects of Methoxyacetic Acid on the Reproductive Organs of Male Swiss Webster Mice (Mus Musculus)Abstract. Methoxyacetic acid (MAA) is one of the metabolites of dimethoxyethyl phthalate (DMEP), which is mainly used as plasticizer in the manufacture of plastics. DMEP could leach from plastics and by entering the body, it will be metabolized into MAA which is teratogenic and toxic to several organs, particularly male reproductive organs. To investigate the effects of MAA on the male reproductive organs, seven-week-old Swiss Webster mice were treated with MAA at the doses of 100, 150, 225, and 300 mg/kg body weight daily by gavage, within four consecutive weeks with one-day interruption in each weekend. Observation was performed on the weight of testis, epididymis and seminal vesicle; the number, motility, and morphology of the spermatozoa obtained from the caudal epididymist; the histological structure of testis, including diameter, epithelial thickness and the performance of seminiferous tubule; the number of spermatogenic cells, as well as the number of Sertoli and Leydig cells. Compared to control the result showed, that testis and epididymis, but not the seminal vesicle decreased in weight. The number and motility of spermatozoa decreased, whereas the abnormal ones increased. The diameter, the epithelial thickness, as well as the percentage of normal (stage VII) seminiferous tubules were reduced, while the percentage of abnormal tubules increased. The administration of MAA led to the degeneration of spermatogenic cells, particularly the pachytene spermatocyte and spermatids, shown by the reduction in their number. The spermatogonia A and the preleptotene spermatocytes were the most resistant spermatogenic cells to MAA. The number of Sertoli and Leydig cells were not affected by MAA, despite toxic phenomenon of Sertoli cells characterized by vacuolization in the cytoplasm was shown. It is concluded that testis is the most susceptible to MAA insult, which subsequently interferes the spermatogenesis of male Swiss Webster mice.
ANALISIS KANDUNGAN BORAKS PADA MAKANAN: STUDI KASUS DI WILAYAH KECAMATAN PAMULANG, TANGERANG SELATAN Rumanta, Maman; Iryani, Krisna; Ratnaningsih, Anna
Jurnal Matematika Sains dan Teknologi Vol 17 No 1 (2016)
Publisher : LPPM Universitas Terbuka

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This study aimed to analyze borax content in food and the effects of food processing on the content of borax in food. This research adopted a survey method. Food samples were obtained from the traditional and modern markets, elementary schools, and supermarkets available in the region of Pamulang Subdistrict. Sampling was done by using a purposive technique. Each sample was qualitatively analyzed for its borax content using a borax test kit. The detected food was then analyzed by using a qualitative analysis (i.e., there are four categories of data); one sample per category was taken to be analyzed quantitatively using the HPLC method in the Laboratorium of Balai Besar Pusat Penelitian dan Pengembangan Pascapanen Pertanian, Bogor. The treatment of food containing the highest level of borax) was conducted by boiling them during a certain period of time (i.e., 5 minutes, 15 minutes, and 30 minutes) and then frying them until well cooked (was not burnt). The collected data were then analyzed descriptively. The results showed that 54% of the samples obtained from the Elementary Schools positively contained borax; as much as 74% of the food samples obtained from traditional markets contained borax positively; while all samples coming from the supermarkets did not contain borax. The content of borax in the detected food in this research ranged between 560 mg/kg up to 17,640 mg/kg. The highest content of borax found in yellow wet noodles (17,640 mg/kg) was far above the maximum level specified by EFSA (2013), that is as much as 4,000 mg/kg. The boiling process was quite effective in lowering the level of borax in food, while the frying process did not actually reduce the level of borax in food. Penelitian ini bertujuan untuk menganalisis kandungan boraks pada makanan dan pengaruh pengolahan makanan terhadap kandungan boraks pada makanan. Penelitian ini dilakukan dengan metode survei. Jenis makanan yang dijadikan sampel dalam penelitian ini adalah jenis makanan yang diperoleh dari pasar tradisional dan modern, sekolah dasar, dan supermarket di wilayah Kecamatan Pamulang. Pengambilan sampel dilakukan dengan menggunakan teknik purposive sampling. Setiap sampel dianalisis kandungan boraksnya secara kualitatif menggunakan test kit boraks. Selanjutnya, makanan yang telah terdeteksi oleh analisis kualitatif (ada empat kategori data), diambil satu sampel per kategori untuk dianalisis secara kuantitatif menggunakan metode HPLC di Laboratorium Balai Besar Pusat Penelitian dan Pengembangan Pascapanen Pertanian, Bogor. Makanan yang terdeteksi mengandung boraks paling tinggi diperlakukan dengan cara direbus dalam beberapa rentang waktu (5 menit, 15 menit, dan 30 menit) dan digoreng sampai matang (tidak sampai gosong). Data yang dikumpulkan dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa 54% dari sampel makanan yang diperoleh dari Sekolah Dasar positif mengandung boraks; sebanyak 74% dari sampel makanan yang diperoleh dari pasar tradisional positif mengandung boraks; sementara semua sampel berasal dari supermarket tidak terdeteksi mengandung boraks. Kandungan boraks dalam makanan yang terdeteksi dalam penelitian ini berkisar antara 560 mg/kg sampai dengan 17.640 mg/kg. Kandungan tertinggi ditemukan dalam mie basah kuning (17.640 mg/kg) jauh di atas kadar maksimum yang ditentukan EFSA (2013) sebanyak 4.000 mg/kg. Proses perebusan cukup efektif dalam menurunkan kadar boraks dalam makanan, sedangkan proses penggorengan tidak mengurangi kadar boraks dalam makanan.
KONSENTRASI TIMBAL (Pb) PADA PERAIRAN DI SEKITAR TELUK JAKARTA Ratnaningsih, Anna; Rahayu, Ucu; Latief, Amril; Rumanta, Maman; Nurdin, Gusti
Jurnal Matematika Sains dan Teknologi Vol 9 No 1 (2008)
Publisher : LPPM Universitas Terbuka

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Abstract

he purpose of this study is to get information about river that has the greatest contribution to cause Pb pollution in the Jakarta Bay. Nine (9) of 13 rivers flowing into Jakarta Bay were chosen. They were Citarum, Bekasi, Cilincing, Marunda, Ciliwung, Sunter, Cideng, Angke, and Cisadane. Sampling were taken in two periods of times, rainy and dry season of 2006 with triple repeatations. pH and temperature of samples as proponent data were measured insitu. Pb concentration in the water of the river was measured by using AAS flame in the laboratory of Balai Penelitian Tanah Bogor. Data was analyzed statistically (one way ANOVA and t-test) by using SPSS 11.5 software. It was shown that Pb concentration of estuary water surrounding Jakarta Bay has been exceeding threshold level. There was a tendency that Pb concentrations of water in rainy season are lower than that in dry season except in Ciliwung River. The anomaly of Ciliwung River was probably caused by some industries which throw their wastes into Ciliwung River in the rainy season. It was concluded that all of 9 rivers have a significant contribution to Pb pollution in Jakarta Bay, and the most was from Ciliwung River.
KUALITAS PELAKSANAAN TUTORIAL TATAP MUKA S-1 PENDAS DI UPBJJ-UT PANGKALPINANG Simanjuntak, Haholongan; Rumanta, Maman
Jurnal Pendidikan Terbuka Dan Jarak Jauh Vol 14 No 2 (2013)
Publisher : LPPM Universitas Terbuka

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This article is a descriptive study that describes the quality of face-to-face tutorials in undergraduate studies at UPBJJ Pangkalpinang during the registration period of 2011.2. The method used in this study is a survey using a questionnaire. The population of the study consists of all tutors and undergraduate students that conduct face-to-face tutorials in all study groups throughout UPBJJ-UT Pangkalpinang region during the registration period of 2011.2. Samples were taken with a purposive random sampling. The aim of this study is focused on the implementation of the tutorial for undergraduate students. The study will also discuss a few other aspects: (a). Students profile (b). Tutors: knowledge and skills of tutors, and tutors commitment in implementing the tutorial. (c). Teaching materials and supplies. (d). Tutorial location and facilities. The results of this experiment are: (1) Students attendance and participation in tutorial activities are good enough, as seen during the tutorial almost all the students are present and active. Most students wish there is a face-to-face tutorial conducted for all offered courses. (2). Tutorial implementation run well according to the schedules. The tutorial provided good support to students in their learning process at UT and these activities can eliminate the perception that learning at UT is only needed when the final exams approach. (3). Tutors capability in implementing face-to-face tutorials in undergraduate studies within the 2011.2 PGSD registration period is categorized as good, partly because the S-1 PGSD tutors had received training and capacity building before carrying out the tutorial. (4). The District Education Office takes a solid role in organizing tutorials, including provision of tutorial venues (usually done in school buildings), provision of accommodation for students who live remotely from the tutorial venue, and keeping students informed on tutorial schedules and venues. Artikel ini adalah penelitian deskriptif yang menggambarkan kualitas TTM S-1 Pendas di UPBJJ-UT Pangkalpinang pada masa registrasi 2011.2. Metode yang digunakan dalam penelitian ini adalah survei dengan menggunakan angket dan observasi. Populasi dalam penelitian ini seluruh tutor dan mahasiswa program S-1 Pendas yang melaksanakan kegiatan TTM di seluruh pokjar yang ada di wilayah UPBJJ-UT Pangkalpinang masa registrasi 2011.2. Sampel diambil dengan purposive random sampling. Tujuan penelitian ini difokuskan pada pelaksanaan tutorial bagi mahasiswa program S-1 Pendas. Selain itu dibahas pula berbagai aspek antara lain: (a). Profil mahasiswa (b). Tutor: pengetahuan dan keterampilan tutor dan komitmen tutor dalam melaksanakan tutorial. (c). Bahan Ajar dan bahan pendukung. (d). Tempat dan fasilitas kegiatan tutorial. Hasil penelitian ini adalah: (1) Pada kegiatan tutorial, kehadiran dan peran serta mahasiswa cukup baik, hal ini terlihat pada saat tutorial berlangsung hampir semua mahasiswa hadir dan aktif. Sebahagian besar mahasiswa menginginkan agar semua matakuliah yang ditawarkan dilaksanakan tutorial tatap muka. (2). Pelaksanaan tutorial pada prinsipnya berjalan dengan baik sesuai dengan jadwal yang telah ditentukan. Pelaksanaan Tutorial sangat membantu mahasiswa dalam proses pembelajaran di UT dan kegiatan ini dapat menghilangkan kesan bahwa kuliah di UT hanya cukup belajar menjelang UAS saja. (3). Kemampuan para Tutor dalam pelaksanaan TTM S-1 PGSD masa registrasi 2011.2 termasuk kategori baik, antara lain karena para tutor S-1 PGSD telah mengikuti pelatihan dan pembekalan tutor sebelum melaksanakan tutorial. (4). Peran Dinas Pendidikan Kabupaten/Kota sangat baik dalam penyelenggaraan tutorial, antara lain dengan menyediakan tempat tutorial (biasanya dilakukan di gedung-gedung sekolah), menyediakan tempat tinggal bagi mahasiswa yang rumahnya jauh dari tempat tutorial serta menginformasikan kepada mahasiswa tentang waktu dan tempat pelaksanaan tutorial.
Pengaruh Model Pembelajaran Project Based Learning dan Keterampilan Kolaborasi terhadap Hasil Belajar IPA Siswa Alamsyah Alamsyah; Maman Rumanta; Widiasih Widiasih
Jurnal Elementaria Edukasia Vol 4, No 2 (2021): Oktober
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31949/jee.v4i2.3147

Abstract

Penelitian ini dilatar belakangi oleh rendahnya hasil belajar siswa yang diakibatkan oleh kurang tepatnya metode pembelajaran yang digunakan oleh guru dalam proses pembelajaran dan lemahnya keterampilan kolaborasi siswa sebagai modal dalam belajar IPA. Tujuan dari penelitian ini adalah mendeskripsikan pengaruh project based learning tehadap hasil belajar pada mata pelajaran IPA dan mendeskripsikan perbedaan hasil belajar IPA pada tingkat keterampilan kolaborasi siswa yang berbeda. Penelitian ini merupakan penelitian eksperimen dengan pola pretest-posttest control group design yang dilakukan pada siswa kelas IV SDN Kecamatan Damar,  data hasil penelitian diperloeh dengan menggunakan instrumen berupa lembar tes hasil belajar siswa dan lembar observasi keterampilan kolaborasi, data dianalisis dengan menggunakan uji two way ANOVA. Hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan hasil belajar IPA antara siswa yang belajar dengan mengguunakan project based learning dengan siswa yang belajar tanpa menggunakan project based learning. Rata-rata hasil belajar siswa yang memiliki keterampilan kolaborasi tinggi cenderung lebih besar jika dibandingkan dengan rata-rata hasil belajar siswa yang memiliki keterampilan kolaborasi rendah yang dipengaruhi oleh penggunaan model project based learning berpengaruh terhadap hasil belajar siswa.
The Influence of Work Discipline, Work Ethos and Work Environment on Employee Work Achievement: Lessons from Local Organization in an Emerging Country Javed Octovianus Sipahelut; Anita Erari; Maman Rumanta
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 2 (2021): Budapest International Research and Critics Institute May
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i2.1996

Abstract

The Office of Industry, Trade, Cooperatives and Small and Medium Enterprises of Yapen Islands Regency, Papua, as a local government agency is obliged to foster, protect, and pay attention to issues related to industry, trade, cooperatives, and small and medium enterprises. Good employee performance is important in order to support the smooth running of official duties. This study aims to examine and analyze the effect of work discipline, work ethic and work environment on employee work performance at the Department of Industry, Trade, Cooperatives and Small and Medium Enterprises, Yapen Islands Regency. Data collection techniques were carried out by distributing questionnaires and interviews. The sample used in this study were 66 respondents. The hypothesis was tested by multiple linear regression analysis with the help of SPSS software. The results of the analysis show that work discipline has a significant positive effect on employee work performance, the higher the level of employee discipline, the higher the work performance. Work ethic has a significant positive effect on employee work performance, the better the work ethic of the employee, the better the work performance. The work environment has a significant positive effect on employee work performance, the better the work environment, the better the employee's work performance.
Kinerja Pegawai Dipengaruhi oleh Komunikasi, Iklim Organisasi dan Motivasi Kerja Daud Woru; Anita Erari; Maman Rumanta
Alignment:Journal of Administration and Educational Management Vol 4 No 1 (2021): Alignment:Journal of Administration and Educational Management
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/alignment.v4i1.2001

Abstract

This study aims to describes the ability of communication, organizational climate, and work motivation on the create of employee performance in the Yapen Selatan District. The research method used is quantitative research using statistical procedures. The research instrument was a questionnaire with a Likert scale. The sample in this study were 52 employees in the Yapen Selatan District. Multiple linear regression test with the help of SPSS 22 software is used to determine the effect of independent variables on the dependent variable. The results showed that the variables of communication and work motivation had a significant positive effect on employee performance. While the organizational climate variable has a significant negative effect on employee performance. Communication, organizational climate, and work motivation together have an effect on the performance of South Yapen District employees. Keywords: Communication, Organizational Climate, Work Motivation, Employee Performance.
Development of Natural Science Teaching Materials (IPA) Based Outdoor Basic Learning to Improve Creative Thinking Skills of Students in Class 2 Toboali State School 4, Bangka Selatan Regency Elly Elly; Maman Rumanta; Widiasih Widiasih
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 4 (2021): Budapest International Research and Critics Institute November
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i4.3313

Abstract

This study aims to develop teaching materials outside the classroom (essential outdoor learning) to increase student creativity. Teaching materials as learning resources are developed by taking the environment outside the classroom that is related to students' daily lives. Natural Sciences (IPA) teaching materials consist of Student's Books and Teacher's Books, used in class 2 elementary school (SD) Negeri 4 Toboali. This teaching material contains essential competencies about the experimental results of solid objects that do not change shape. This study uses the Research and development model Borg and Gal (2002) with nine steps. At the validation stage, it was found that the Class 2 Science Teaching Materials Based on the Outside of the Classroom and the Learning Implementation Plan (RPP) had met the element of validity with minor revisions. The formative evaluation results through 3 stages after being revised obtained input that the Out-of-Class-Based Science Teaching Materials are suitable for use in science learning for Grade 2 SD Negeri 4 Toboali. Based on the test scores, the Out-of-Class-Based Science Teaching Materials can help Class 2 students of SD Negeri 4 Toboali understand learning materials, especially in Theme 2 science learning.
THE EFFECTS OF SCIENTIFIC-BASED LEARNING STRATEGY (IMAGES MEDIA AND LECTURE METHOD) AND STUDENTS’ LEARNING MOTIVATION TOWARDS SCIENCE ACHIEVEMENT ON STUDENTS OF CIRUAS 2 ELEMENTARY SCHOOL Rodiyah, Rodiyah; Santosa, Cecep Anwar Hadi Firdos; Rumanta, Maman
Jurnal Penelitian Pendidikan IPA Vol 5, No 1 (2020): Juni 2020
Publisher : Perkumpulan Pendidik IPA Indonesia (PPII)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jppipa.v5n1.p6-14

Abstract

This study aims to determine the effects of scientific-based learning strategy (images media and lecture method) and students’ learning motivation towards the students’ achievement of learning science. This research applied 2 x 2 factorial design, a type ofquasi-experimental design. Results are as follows: (1) there are differences in the students’ achievement of learning science between students who are taught using thescientific-basedlearning strategy withimages media and students who are taught usingscientific-basedlearning strategywith lecture method, (2) there are differences in the students’ achievement of learning science between students who have a strong learning motivation and students who have a weak learning motivation, (3) For students who have a strong learning motivation, whether the students’ achievement of learning science are higher when taught withscientific-based learning strategywith images media than with the lecture method, (4) For students who have a weak learning motivation, are the results of learning science higher when taught with the scientific-based learning strategy with lecture method compared to thescientific-basedlearning strategy withimages media, (5) there is an interaction between scientific-based learning strategyand students’ learning motivation towards students’ achievement of learning science.Keywords: Scientific Based Learning, students’ learning motivation, students’ achievement of learning science
Pengaruh Model Inquiry-Based Learning dan Motivasi Belajar Terhadap Keterampilan Berpikir Kritis Siswa Kelas V SD Udan Miharja; Maman Rumanta; Ucu Rahayu
Jurnal Elementaria Edukasia Vol 4, No 1 (2021): April
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31949/jee.v4i1.3027

Abstract

Kemampuan berpikir kritis berperan penting dalam mempersiapkan siswa menjadi pemecah masalah yang baik serta mampu membuat keputusan maupun kesimpulan yang dapat dipertanggung jawabkan secara akademis. Rendahnya keterampilan berpikir kritis siswa pada mata pelajaran IPA menjadi latar belakang dilakukannya penelitian ini. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh model inquiry based learning dan motivasi belajar terhadap keterampilan berpikir kritis siswa. Metode penelitian yang digunakan dalam penelitian ini adala quasi eksperimen yang mana penelitian ini menggunakan dua kelompok sampel yaitu kelas eksperimen dan kelas kontrol. Pemilihan sampel penelitian dilakukan dengan menggunakan random sampling. Data penelitian dilakukan dengan menggunakan tes untuk melihat keterampilan berpikir kritis dan lembar observasi untuk melihat motivasi belajar siswa. Data yang didapat dianalisis dengan menggunakan analisis varians dua jalur (Two Way ANOVA) untuk menganalisis pengaruh antara dua variabel. Hasil penelitian menunjukkan adanya pengaruh inquiry based learning terhadap keterampilan berpikir kritis siswa yang ditunjukkan dengan nilai signifikansi sebesar 0,004 < 0,05; terdapat perbedaan keterampilan berpikir kritis siswa yang memiliki motivasi rendah dan tinggi, hal ini terlihat dari nilai signifikansi sebesar 0,000 < 0,05; akan tetapi tidak terdapat pengaruh interaksi antara model inquiry based learning  dengan motivasi belajar siswa yang terlihat dari nilai signifikansi sebesar 0,736 > 0,05.