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Efek Penghambatan Terhadap Pertumbuhan Tumor Paru dan Uji Ketoksikan Akut Ekstrak Kapsul Chang Sheuw Tian Ran Ling Yao Pada Mencit (Mus musculus) dan Tikus (Ratus tanezumi) Fudholi, Ahmad; Meiyanto, Edy; Donatus, Imono Argo; Nurrochmad, Arief; Hakim, Arief Rahman; Murwanti, Retno
JURNAL BIOLOGI INDONESIA Vol 5, No 1 (2008): JURNAL BIOLOGI INDONESIA
Publisher : Perhimpunan Biologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.692 KB) | DOI: 10.14203/jbi.v5i1.3202

Abstract

Inhibitory Phases Effect of The Lung Cancer And Acute Toxicity of Chang Sheuw Tian RanLing Yao Capsule Extracts in House mice (Mus musculus) and Rat (Ratus tanezumi). Effortsto find anticancer agents have been developed nowadays, some of them are focused in traditionalherbs. One of the available products in the market that claims effective to cure cancer isthe Chang Sheuw Tian Ran Ling Yao, PT. Daun Teratai extract containing CAPSULE (CSTRLYextract). The aim of this study is to examine of confession of some people which are usingthe useful of medicine CSTRLY extract capsule through inhibitor laboratory effect of theCSTRLY extract in the initiation and post initiation phases of the lung cancer in mice and ratsthat had been induced by eather Benzo[?]pyrene (BP) or Dimetilbenz[?]antrazene (DMBA)and to clarify the potency of acute toxicity and specific toxic manifestations of thephytopharmaca.The results showed that the CSTRLY extract can reduce the cancer incidence caused bycarcinogen, BP and DMBA. Moreover, the extract can also inhibit the cancer growth in themice and rats, especially in the early post-initiation phase. Further, the histopathologicalevaluation showed that up to the highest dose level that technically could be administrated tothe animals (12500 mg/kg bw), no animal death was occurred. Furthermore, the ADG values formale and female rats indicated no significant different (P > 0.05) that relative to the controlgroup. No animals were shows physical symptom as a toxic manifestation. It’s indicated thatthe phytopharmaca no influenced to somatomotor and nervous system. Within the dose rangeadministrations, no detectable morphological toxic effects or histophatological changes of theliver, spleen, heart, and lungs were observed. the acute toxicity value of Chang Sheuw TianRan Ling Yao Capsule was very low (or minimal almost non-toxic with LD50 > 12500 mg/kg bw)and the spectrum of toxic effects of the phytopharmaca were considered negligible.Key words: Ekstract, CSTRLY, mice and rat, BP, DMBA, carsinogenesis, lung cancer
EFEK PENGHAMBATAN TERHADAP PERTUMBUHAN TUMOR PARU DAN UJI KETOKSIKAN AKUT EKSTRAK KAPSUL CHANG SHEUW TIAN RAN LING YAO PADA MENCIT (MUS MUSCULUS) DAN TIKUS (RATUS TANEZUMI) Fudholi, Ahmad; Meiyanto, Edy; Donatus, Imono Argo; Nurrochmad, Arief; Hakim, Arief Rahman; Murwanti, Retno
JURNAL BIOLOGI INDONESIA Vol 5, No 1 (2008): JURNAL BIOLOGI INDONESIA
Publisher : Perhimpunan Biologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/jbi.v5i1.3202

Abstract

Inhibitory Phases Effect of The Lung Cancer And Acute Toxicity of Chang Sheuw Tian RanLing Yao Capsule Extracts in House mice (Mus musculus) and Rat (Ratus tanezumi). Effortsto find anticancer agents have been developed nowadays, some of them are focused in traditionalherbs. One of the available products in the market that claims effective to cure cancer isthe Chang Sheuw Tian Ran Ling Yao, PT. Daun Teratai extract containing CAPSULE (CSTRLYextract). The aim of this study is to examine of confession of some people which are usingthe useful of medicine CSTRLY extract capsule through inhibitor laboratory effect of theCSTRLY extract in the initiation and post initiation phases of the lung cancer in mice and ratsthat had been induced by eather Benzo[?]pyrene (BP) or Dimetilbenz[?]antrazene (DMBA)and to clarify the potency of acute toxicity and specific toxic manifestations of thephytopharmaca.The results showed that the CSTRLY extract can reduce the cancer incidence caused bycarcinogen, BP and DMBA. Moreover, the extract can also inhibit the cancer growth in themice and rats, especially in the early post-initiation phase. Further, the histopathologicalevaluation showed that up to the highest dose level that technically could be administrated tothe animals (12500 mg/kg bw), no animal death was occurred. Furthermore, the ADG values formale and female rats indicated no significant different (P > 0.05) that relative to the controlgroup. No animals were shows physical symptom as a toxic manifestation. It?s indicated thatthe phytopharmaca no influenced to somatomotor and nervous system. Within the dose rangeadministrations, no detectable morphological toxic effects or histophatological changes of theliver, spleen, heart, and lungs were observed. the acute toxicity value of Chang Sheuw TianRan Ling Yao Capsule was very low (or minimal almost non-toxic with LD50 > 12500 mg/kg bw)and the spectrum of toxic effects of the phytopharmaca were considered negligible.Key words: Ekstract, CSTRLY, mice and rat, BP, DMBA, carsinogenesis, lung cancer
Implementasi FingerPrint dan Short Message Service Gateway pada Sistem Presensi Purnomo , Rakhmat; Fudholi, Ahmad
Jurnal Kajian Ilmiah Vol. 20 No. 1 (2020): Januari 2020
Publisher : Lembaga Penelitian, Pengabdian Kepada Masyarakat dan Publikasi (LPPMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (518.213 KB) | DOI: 10.31599/jki.v20i1.73

Abstract

The research aims to apply the fingerprint and Short Message Service technology in the attendance system. Presence or attendance is an important activity in the lecturing process. SMK Global Teknologi has a problem in the student attendance data. The human error factor in captured student attendance is a problem in itself. On the other hand, there are cases of students who went to school but did not arrive at school to become complaints from parents. Fingerprint technology has been proven to be able to validate someone as proof of attendance, while the SMS gateway is proven to be a reliable telecommunications technology for data communication. The research method used was to conduct observations at the SMK Global Technologi. The interview method was carried out with the principal, representatives of parents, teachers, and students. The system development method used is Waterfall which consists of the stages of planning, analysis, design, finally implementation. The testing method used a black-box. The results of the research are the application of student attendance information systems with an attendance system indicator that has been integrated between parents, teachers, homeroom teachers. So that student attendance data can be directly known. Keywords: Attendance System, Fingerprint, SMS Gateway Abstrak Tujuan penelitian ini untuk menerapkan teknologi fingerprint dan Short Message Service (SMS) dalam sistem presensi. Presensi atau kehadiran merupakan kegiatan yang penting dalam proses pembelajaran. SMK Global Teknologi memiliki masalah dalam data presensi siswanya. Faktor kesalahan manusia dalam merekap kehadiran siswa menjadi masalah tersendiri. Disisi lain adanya kasus peserta didik yang berangkat ke sekolah tetapi tidak sampai kesekolah menjadi keluhan orang tua. Teknologi fingerprint telah terbukti dapat memvalidasi seseorang sebagai bukti kehadiran, sedangkan SMS gateway terbukti untuk sebagai teknologi telekomunikasi yang handal untuk komunikasi data. Metode penelitian yang digunakan adalah dengan melakuan observasi di SMK Global Teknologi. Metode wawancara dilakukan kepada kepala sekolah, perwakilan orang tua, guru, dan siswa. Metode pengembangan sistem yang digunakan adalah Waterfall yang terdiri dari tahapan perencanaan, analisis, perancangan, dan penerapan. Metode pengujian menggunakan black-box. Hasil dari penelitian ini adalah diterapkannya sistem informasi kehadiran peserta didik dengan indikator sistem kehadiran sudah terintegrasi antara orang tua, guru, wali kelas. Sehingga data kehadiran siswa dapat secara langsung diketahui. Kata kunci: Sistem Kehadiran, Fingerprint, SMS Gateway
ANIMASI INTERAKTIF PEMBELAJARAN PENGENALAN DAN PERANCANGAN JARINGAN KOMPUTER Fudholi, Ahmad
PIKSEL : Penelitian Ilmu Komputer Sistem Embedded and Logic Vol 3 No 1 (2015): Maret 2015
Publisher : LPPM Universitas Islam 45 Bekasi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT Computer network is one of the main subjects at computer and network engineering vocational high school level that require practice in the delivery. Utilization of information technology and communication in the learning process at school is done through the delivery of learning methods based on technology through the learning media in the form of interactive animation. In this research, it is done by creating interactive animation learning introduction of computer network. By creating an animation application of computer network learning, it makes easier for students to learn it and improve student's learning achievement. Keyword : animation, learning media,design ABSTRAK Jaringan Komputer merupakan salah satu mata pelajaran utama pada jenjang Sekolah Menengah Kejuruan Teknik Komputer dan Jaringan yang memerlukan praktek di dalam penyampaiannya. Pemanfaatan teknologi informasi dan komunikasi dalam proses pembelajaran di sekolah dilakukan melalui penyampaian metode pembelajaran yang berbasis teknologi yaitu melalui media pembelajaran dalam bentuk animasi interaktif. Dalam penelitian ini dilakukan pembuatan animasi interaktif pembelajaran pengenalan jaringan computer. Dengan dibuatnya aplikasi animasi pembelajaran jaringan komputer maka memudahkan siswa dalam mempelajarinya sehingga dapat meningkatkan prestasi belajar para siswa.
Mathematical Model of the Thermal Performance of Double-Pass Solar Collector for Solar Energy Application in Sierra Leone Bangura, Abu Bakarr Momodu; Hantoro, Ridho; Fudholi, Ahmad; Uwitije, Pierre Damien
International Journal of Renewable Energy Development Vol 11, No 2 (2022): May 2022
Publisher : Center of Biomass & Renewable Energy, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/ijred.2022.41349

Abstract

The primary aim of this study was to utilize thermal energy for drying applications on March 21 (day of the year, n = 80) for the climatic weather conditions of Freetown, Sierra Leone. We evaluated the heat absorption of a double-pass solar air collector based on its configuration and exterior input variables before it was designed and mounted at the location of interest. This study considered a steady-state heat transfer using the thermal network procedure for thermodynamic modeling of a double-pass solar collector developed for drying and heating purposes. A mathematical model defining the thermophysical collector properties and many heat transfer coefficients is formed and numerically solved for this purpose. Indeed, this helped us generate the hourly temperature of different heat collector components, which aided in the performance evaluation of the system. The impact of the fluid flowing inside the collector on the temperature of the exit air was analyzed. It was observed that a flow rate of 0.02 kg/s produced an output of 91.72°C. The system's thermal efficiency improves with increased flow rate at various solar radiation intensities. It was observed that the thermal efficiency of the collector increases from 29% to 67% at flow rates of 0.01–0.3 kg/s. Collector lengths of 1.4 and 2.4 m are observed to be economically viable. An increase in the flow rate caused an increase on the efficiency. The hourly outputs for the collector components were represented graphically, and the curve patterns were similar to those of previous studies.