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All Journal Acta Pharmaciae Indonesia : Acta Pharm Indo
Nur Amalia Choironi
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Medicine & Pharmacology

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Aktivitas Antibakteri Ekstrak Etil Asetat Kulit Manggis (Garcinia mangostana L.) Terhadap Staphylococcus epidermidis Vania Reani Valmai; Nur Amalia Choironi; Sunarto Sunarto
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 7 No 1 (2019): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.417 KB) | DOI: 10.20884/1.api.2019.7.1.2415

Abstract

Kulit manggis (KM) (Garcinia mangostana L.) diketahui memiliki kemampuan antibakteri Penelitian ini bertujuan untuk mengetahui adanya kandungan polifenol dan flavonoid pada kulit manggis (Garcinia mangostana L.) dan mengetahui kemampuan antibakteri. Ekstraksi dilakukan dengan metode maserasi selama 72 jam menggunakan pelarut etil asetat. Uji antibakteri ekstrak etil asetat kulit manggis terhadap Staphyloccocus epidermidis dilakukan dengan metode difusi cakram Kirby Bauer. Variasi konsentrasi ekstrak yang digunakan yaitu 4%, 6%, 8%, dan 10% dengan kontrol positif klindamisin, kontrol negatif akuades. Ekstrak etil asetat G. mangostana L. mengandung polifenol dan flavonoid. Diameter zona hambat rata-rata untuk konsentrasi 4%, 6%, 8%, dan 10% secara berurutan yaitu 12 mm; 12 mm; 12,5 mm; 13,5 mm. Nilai tersebut berbeda signifikan dengan kontrol negatif yang tidak menghambat pertumbuhan Staphyloccocus epidermidis.
Antioxidant Activity and Total Flavonoid Content of Zingiber aromaticum Val. Sunarto Sunarto; Nur Amalia Choironi; Faridah Laeli Syarifah
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 8 No 2 (2020): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2020.8.2.3517

Abstract

Increase prevalence of degenerative disease caused by free radicals. Zingiber aromaticum is known to be used as traditional medicine. The purpose of this study was to known antioxidant activity and total flavonoid content of Z. aromaticum from Lembang. The extract was obtained by maceration method using ethanol solvent. Total flavonoid content was carried out using spectrophotometry. The antioxidant activities was carried out by Ferric Reducing Antioxidant Power (FRAP) method. Corellation between total flavonoid content and antioxidant activities using statistic with Pearson’s Correlation method. The results shown that antioxidant activities of Z. aromaticum is weak with total flavonoid content is 9,924 ± 0,544 mg quercetin/ g extract.
Co-Authors Faridah Laeli Syarifah Sunarto Sunarto Vania Reani Valmai