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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Manajemen STIE Muhammadiyah Palopo Jurnal Analis Farmasi Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Tamaddun : Jurnal Pendidikan dan Pemikiran Keagamaan Jurnal Ilmiah Wahana Pendidikan JAF (Jurnal Analis Farmasi)
Tutik Tutik
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Journal : Pharmaciana: Jurnal Kefarmasian

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Evaluation and clinical activity test of various concentrations of peel-off gel mask of robusta coffee seed extract (Coffea canephora) as anti-aging Angga Saputra Yasir; Agesta Yesti Renita; Tutik Tutik
Pharmaciana Vol 13, No 1 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (548.035 KB) | DOI: 10.12928/pharmaciana.v13i1.23965

Abstract

 Robusta coffee beans contain antioxidant compounds having anti-aging properties. This study aims to determine the content of secondary metabolites in robusta coffee bean extract, anti-aging effectiveness, and the best peel-off gel mask preparation concentration. The extraction method in this study used maceration with 96% ethanol as solvent. The extraction results were carried out by phytochemical screening and formulation of peel-off gel mask preparations, then tested for anti-aging effectiveness using 12 female volunteers and observed signs of aging, including pores, spots, wrinkles, and moisture for four weeks. Robusta coffee bean extraction results obtained a yield of 9.2%. The results of phytochemical screening showed that robusta coffee bean extract contains flavonoid compounds, alkaloids, tannins, and saponins. The results of the evaluation of the 0.5% formula of robusta coffee bean extract were the most preferred by volunteers. The best effectiveness and concentration test results were found in the peel-off gel mask preparation of 2% robusta coffee bean extract formula (F2) compared to blank and F1 (p-value <0.05). The percentage of improvement in the condition of the volunteers' skin, including pores, spots, wrinkles, and moisture, is 21.88 ± 4.22%, 21.57 ± 3.25%, 17.71 ± 2.44%, and 21.25 ± 3.62%, respectively.
Co-Authors admin admin Agesta Yesti Renita Angga Saputra Yasir Ayu Indah Permatasari Dewi Chusniasih Erisa Mutiara Rahma Delvina Gusti Ayu Rai Saputri Heni Krisnatalia Idah Kusuma Dewi Ika Hidayanti Mistriani, Nina Niken Feladita Santoso Ode Man Arfa Ladamay Pigdayanti Pigdayanti Selvi Marcellia Solichoel Solichoel Vida Elsyana