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UJI EFEKTIVITAS ANTIHIPERURISEMIA EKSTRAK AIR DAUN SALAM (Syzygium polyanthum Wight.) TERHADAP MENCIT JANTAN (Mus musculus) YANG DIINDUKSI JUS HATI AYAM DAN KALIUM OKSONAT Hidayah, Nurul; Hasanah, Fenny; Gunawan, Muhammad; Lestari, Anggun
JURNAL PENELITIAN SAINTIKA Vol 18, No 1 (2018): MARET 2018
Publisher : JURNAL PENELITIAN SAINTIKA

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Abstract

Hiperurisemia disebabkan oleh sintesa purin berlebihan dalam tubuh karena pola makan yang tidak sehat dan proses pengeluaran asam urat dari dalam tubuh yang mengalami gangguan. Penggunaan obat-obat sintesis untuk hiperurisemia bukan tanpa risiko efek samping yang merugikan, sehingga diperlukan terapi alternative dari alam. Daun salam dipercaya dapat menurunkan kadar asam urat. Tujuan dari penelitian ini adalah untuk mengetahui potensi efektivitas ekstrak air daun salam terhadap penurunan kadar asam urat mencit jantan yang diinduksi dengan jus hati ayam 0,2% dan kalium oksonat 250 mg/kg BB. Tahapan penelitian meliputi identifikasi tanaman, pembuatan simplisia dan ekstrak, standarisasi dan skrining fitokimia, serta pengujian efek antihiperurisemia. Hewan uji yang digunakan sebanyak 24 ekor, yang dibagi menjadi 6 kelompok uji. Pembagian kelompok hewan uji terdiri atas kelompok normal, induksi, pembanding, ekstrak air daun salam (EADS) dosis 50 mg/kg BB, 100 mg/kg BB, dan 200 mg/kg BB. Parameter efek antihiperurisemia yang diamati adalah kadar asam urat darah hewan uji. Data yang diperoleh selanjutnya diolah secara statistik dengan interval confidency 95%. Hasil uji skrining fitokimia menunjukkan bahwa simplisia dan EADS mengandung tannin, flavonoid, saponin, glikosida, dan alkaloid. Semua kelompok dosis EADS menunjukkan potensi antihiperurisemia yang tidak berbeda signifikan dengan kelompok pembanding yang digunakan.
KEWENANGAN DEWAN PEMBINA DAN PENGENDALI PENGELOLAAN KOLABOATIF (DP3K) TAMAN NASIONAL KAYAN MENTARANG (TNKM) NASIONAL KAYAN MENTARANG (TNKM) Gunawan, Muhammad
JURNAL AKTA YUDISIA Vol 2, No 1 (2017): Jurnal Akta Yudisia Vol. 2 Nomor 1
Publisher : Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (268.633 KB) | DOI: 10.35334/ay.v2i1.977

Abstract

Abstract KMNP (Taman Nasional Kayan Mentarang) collaborative management essentially an innovation in the management of National Parks in Indonesia that promote mutual interests, shared responsibility, the role and benefits between government, local communities and NGOs. In this paper, the issue raised is the authority of the Dewan Pembina dan Pengendali Pengelolaan Kolaboratif (DP3K) KMNP. The aim of this study was to determine and analyze the authority of the Board of Trustees and Collaborative Management Controller (DP3K) Kayan. This type of research is the study of normative juridical approach to legislation and conceptual approach and the use of primary and secondary law with a qualitative analysis approach. Based on the results, the conclusion that the authority DP3K TNKM among others embodies the aspirations of the parties in order to develop and control the implementation of collaborative management KMNP.Keywords: National Parks, collaborative management, Authority.
RASIO HUBUNGAN NILAI DAYA DUKUNG TIANG PANCANG BERDASARKAN PENGUJIAN SONDIR, KALENDERING DAN TES PDA PADA JEMBATAN PELAWA KABUPATEN PARIGI MOUTONG Gunawan, Muhammad; Oktaviana, Ida Sri; B., Arifin
JOURNAL TEKNIK SIPIL DAN INFRASTRUKTUR Vol 4, No 1 (2014)
Publisher : Jurusan Teknik Sipil Universitas Tadulako

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Abstract

Bearing capacity of pile foundation bearing capacity is influenced by several factors, such as the amount of applied loads and non-homogeneous soil characteristics. To determine the bearing capacity of single pile foundation the static method is used on the basis of CPT data and dynamic methods based on dynamic pile and PDA tests. Pile foundations of the Pelawa bridge used in this study are located in the District of Parigi - Moutong. The study of literatures and secondary data such as the data of driven pile equipment, driven piles , CPT, dynamic pile tests, and PDA tests are used for analyzing the pile bearing capacity . Meyerhof method, Aoki de Alencar, LCPC, Price and Waldre, and Schmertmann are used to determine the bearing capacity of pile based on sondir (CPT) data. The dynamic pile tests data are used to calculate the bearing capacity of the piles by using methods of Hiley, Olsen and Flaate , Enginering News Record (ENR) , Janbu Mansur and Hunter , and AASHTO . The results show that  the lowest dan the highest of the ultimate bearing capacities  for static methods (CPT data) are  114.096 tons (Aoki De Alencar) and 305.479 tons (Schmertmann) respectively. Kalendering method (dynamic pile data) show that the lowest value of 284.22 tons were obtained from equation given by Hiley and the highest 1450.26 tons were obtained from equation given by  Janbu.The range of 171.2 tons - 174.5 tons were given for PDA test data. The ratio between CPT to PDAs results that are closest to the value of 1 which is 0.938 is the value that obtained from Meyerhof’s equation, while the ratio between dynamic method (kalendering) to PDAs results that are closest to the value of 1 which is 1,660 is the value that obtained from Hiley equation Keywords: single pile bearing capacity, CPT, dynamic pile test, PDA test
Pemetaan Psikografis Kependudukan Untuk Kepentingan Kampanye Pilkada (Studi Kasus: Kota Cimahi) Gunawan, Muhammad; Sumarno, -; Indrianawati, -
REKA GEOMATIKA Vol 2016, No 2 (2016)
Publisher : Institut Teknologi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1493.523 KB) | DOI: 10.26760/jrg.v2016i2.1853

Abstract

ABSTRAKPemilihan kepala daerah (pilkada) memberikan kesempatan kepada masyarakat untuk memilih kepala daerahnya tanpa melalui suatu perwakilan. Dalam pelaksanaan pilkada terdapat proses kampanye yang bertujuan meyakinkan pemilih untuk memilih calon pasangan tertentu. Tujuan dari pemetaan psikografis kependudukan untuk kepentingan kampanye adalah memberikan data awal kampanye dan lokasi potensial kampanye. Penelitian ini menggunakan metode analisis statistika spasial dengan metode Global Moran’s I dan Getis Ord-­G terhadap data karakteristik kependudukan untuk mengetahui adanya autokorelasi spasial dan bentuk pola kluster antara unit wilayah (kelurahan) di Kota Cimahi. Berdasarkan hasil analisis statistika spasial, dapat diketahui bahwa di seluruh kelurahan Kota Cimahi, data awal kampanye yang relevan adalah data karakteristik pekerjaan dan agama. Karakteristik pendidikan relevan di seluruh kelurahan Kota Cimahi, kecuali Kelurahan Cimahi dan Karangmekar. Karakteristik usia juga relevan di seluruh kelurahan Kota Cimahi, kecuali Kelurahan Cimahi dan Pasirkaliki.Kata kunci: kampanye, statistika spasial, autokorelasi, pola klusterABSTRACTRegional heads election (Pilkada) has given an opportunity to people for choosing their regional heads without any delegation in general election. The general election includes campaign process, which aims to select a certain candidate. In the campaign process, psychographic mapping of demography aims to give preliminary data and potential location of the campaign. This research has used spatial statistical analysis using Global Moran's I and Getis Ord-­G methods for analysing demographic characteristics. The methods aim to know spatial autocorrelation as well as cluster pattern between villages in Cimahi District. The analysis result shows the relevant characteristics in all Cimahi villages are job and religion. Meanwhile, education characteristic is relevant in all villages Cimahi, except Cimahi and Karangmekar villages. Age characteristic is also relevant in all villages Cimahi, except Cimahi and Pasirkaliki villages.Keywords: campaign, spatial statistic, autocorelation, cluster pattern