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Endang Hanani
Universitas Indonesia

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Identifikasi Senyawa Antioksidan Dalam Spons Callyspongia SP Dari Kepulauan Seribu Hanani, Endang
Majalah Ilmu Kefarmasian Vol. 2, No. 3
Publisher : UI Scholars Hub

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Antioxidant activity and identification of antioxidative compounds of Callyspongia sponge from Seribu Island (Kepulauan Seribu) were investigated. The sponge was extracted with acetone and the extract was concentrated using rotary vacuum evaporator. DPPH and tiocyanate methods were used to examine the antioxidant activity of the extract. The extract exhibited strong antioxidant activity in DPPH method with IC50 of 41.21 µg/ml. Chemical analysis indicated that the antioxidative compound in the sponge was alkaloid group.
Pembuatan Teh Herbal Campuran Kelopak Bunga Rosella (Hibiscus sabdariffa) dan Herba Seledri (Apium graveolens) Munim, Abdul; Hanani, Endang; Mandasari, Andita
Majalah Ilmu Kefarmasian
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Rosella calyx (Hibiscus sabdariffa) has been reported exhibited on decreasing high blood pressure activity. Celery herb (Apium graveolens) has been acknowledged as an antihypertension herb with vasodilator and diuretic effect. Combination of the extracts was expected to provide synergism effect on decreasing high blood pressure. This study was intended to prepare the combination of herbal tea from standardized extracts of rosella calyx and celery herb. Standardization of rosella calyx and celery herb included determination of several specific and non-specific parameters. Three different formulas of herbal tea were prepared that would be hedonically tested to obtain the most favorable herbal tea formula from the 30 panelists. The most favorable formula was formula C which contained rosella calyx (2 gram) and celery herb (0.5 gram).
Karakterisasi Ekstrak Etanolik Daun Asam Jawa (Tamarindus indica L.) Munim, Abdul; Hanani, Endang; Rahmadiah, Rahmadiah
Majalah Ilmu Kefarmasian Vol. 6, No. 1
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Leaves of tamarind (Tamarindus indica L.) has been traditionally used to treat some diseases such as: constipation, dyspepsia, flatulence and urinary tract infection. The leaves extract also reported has antibacterial and antidiabetic activities. It is essential to determine its specific and non specific parameters in assesing the quality and safety. The samples collected from three different perferctures. Grounded samples were macerated with ethanol. The extracts were subjected to determine its characteristic parameters. Parameter of quality for the extracts consisted of water content, ethanol-extractive, water-extractive, loss on drying, total ash, acid-insoluble ash, solvent residue and heavy metal content. Phytochemical identification showed that the ex-tract contains flanovoid, tannin, glycosides, and saponin. TLC chromatogram using chloroform-methanol-water (80:12:2) as mobile phase, exhibited 4 spots after sprayed with iron(III) chloride. Total phenolic was determined pectrophotometrically using Folin Ciocalteu reagent, gave 0.35-8.24% total phenolic as gallic acid.
Aktivitas Antioksidan dan Penetapan Kadar Fenol Total Ekstrak Metanol Dedak Bebeapa Varietas padi (Oryza sativa L.) Sugiat, Dede; Hanani, Endang; Mun’im, Abdul
Majalah Ilmu Kefarmasian Vol. 7, No. 1
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Antioxidant has been known to have an important role in the prevention and treatment of diseases. In recent years, many plants have been explored to obtain new antioxidants from natural products. Rice has been known rich in antioxidative compounds. However, there is little attention to the co- or by- products from rice (Oryza sativa) milling plant. One of the products is rice bran. In this study ten varieties of rice bran, which are commonly cultivated varieties in Indonesia were studied their antioxidant activity and total phenolic content. The antioxidant activity was examined by DPPH scavenging assay and total reducing power, while total phenolic content was determined by Folin-Ciocalteu reagent. The results of this study showed that the methanolic extract of IR-64 variety demonstrated the strongest DPPH radical scavenger activity with IC50 350.64 ppm, while in reducing power activity was exhibited by methanolic extract of IR-42 variety. However, the highest total phenolic content (71.85 mg gallic acid equivalent/gram) was found in methanolic extract of OM-4495 rice bran. These result indicated that the methanolic extract of rice bran might potentially be natural antioxidants.
Co-Authors . Azizahwati . Hernasari Abdul Munim Andita Mandasari, Andita Dede Sugiat, Dede Mun’im, Abdul Neneng Siti Silfi Ambarwati Rahmadiah, Rahmadiah Ryany Sekarini Sumali Wiryowidagdo