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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Natur Indonesia Jurnal Kedokteran Brawijaya Jurnal Gizi Klinik Indonesia Jurnal Bioterdidik: Wahana Ekspresi Ilmiah Indonesian Journal of Human Nutrition Jurnal Sains dan Teknologi Farmasi Padjadjaran Journal of Dentistry Majalah Kesehatan FKUB AL-MAIYYAH AcTion: Aceh Nutrition Journal Jurnal Budaya Nusantara Journal of Health Policy and Management Unnes Journal of Public Health El Banar: Jurnal Pendidikan dan Pengajaran Jurnal Aisyah : Jurnal Ilmu Kesehatan Al-MAIYYAH : Media Transformasi Gender dalam Paradigma Sosial Keagamaan SENADA : Semangat Nasional Dalam MengabdI
Dian Handayani
Program Studi Ilmu Gizi, Fakultas Kedokteran,Universitas Brawijaya, Jl. Veteran Malang 65145
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Anticancer potency of black sea cucumber (Holothuria atra) from Mentawai Islands, Indonesia Satari, Mieke Hemiawati; Arma, Utmi; Ilyas, Syafruddin; Handayani, Dian
Padjadjaran Journal of Dentistry Vol 29, No 1 (2017): March
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.217 KB) | DOI: 10.24198/pjd.vol29no1.11654

Abstract

Introduction: The source of bioactive compounds believed to have strong anticancer potency is derived from sea cucumber. Black sea cucumber (Holothuria atra) is a dominant species in Mentawai Islands, West Sumatera, Indonesia. Key factor compound that acts as anticancer in sea cucumber extract is tritepenoid also known as Frondoside A. The purpose of this study was to determine the effectiveness of the active compound taken from black sea cucumber as anticancer. Methods: Methods used was experimental laboratory. Anticancer activity of black sea cucumber was determined by using the MTT assay cytotoxic test to measure the IC50. Cytotoxic test was conducted with Supris clone-1 (SP-C1) derived from cloned lymphadenopathy of patients with oral squamous cell carcinoma on lingual part. Results: It was found that the compounds contained in black sea cucumber has strong anticancer activity (IC50 = 5.25 μL/mL) against SP-C1. Conclusion: Black sea cucumber extract has strong cytotoxic effects against cancer cells SP-C1, therefore black sea cucumber extract potentially developed as a new source of cancer medicine.
Uji Aktivitas Beberapa Subfraksi Etil Asetat dari Herba Meniran (Phyllanthus niruri Linn.) Terhadap Reaksi Hipersensitivitas Kutan Aktif Aldi, Yufri; Mahyudin, Mahyudin; Handayani, Dian
Jurnal Sains dan Teknologi Farmasi Vol 18 No 1 (2013)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

A study on the activity of some ethyl acetate subfraction of meniran herbs (Phyllanthus niruri Linn.) on the cutaneous active hypersensitive reaction has been conducted. The subfraction (1,2, and 3) were at the dose of 50 mg/Kg BW and 100 mg/Kg BW dispersed with 1% tween 80: Chicken egg albumin at concentration 25% and 30% were used as control, all of which were given for 10 days. The Hipersensitivity reaction was observed at day 10th. Result Showed that subfraction 1,2, and 3 at doses 50 mg/Kg BW and 100 mg/Kg BW inhibited hypersensitivity, reaction significantly, the onset of blue skin bump were best given by subfraction 3 (dose 100 mg/Kg BW), the diameter of blue skin bump were best given by subfraction 2 (50 mg/Kg BW) and the intensity of the blue skin bump was besy given by subfraction 2 (100 mh/Kg BW). In summary, the ethyl aceble subfraction of meniron herbs (Phyllanthus niruri Linn.) showed an immunostimulan activity
Isolasi Senyawa Antimikroba dari Spon Laut Pseudoceratina Purpurea Carter Handayani, Dian; Sririta, Martha; Mukhtar, M. Husni
Jurnal Sains dan Teknologi Farmasi Vol 15 No 1 (2010)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

An antibacterial compound (HC 2) has been isolated from the n-hexane fraction of marine sponge Pseudoceratina purpurea Carter. Isolation of  HC 2 compound was done by chromatographic method followed by recrystalization. The antimicrobial assay was guided by diffusion method. The compound HC 2 was white needle crystals with melting point 125-127oC. HC 2 compound was tested for an antibacterial activity at concentrations of 5%, 3% and 1% against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus dan Staphylococcus epidermidis bacterials, respectively. Results showed that HC 2 compound had low activity against all bacteria. Identification and characterization of the active compound was confirmed by chemical reactions and infrared spectrum data. HC 2 compound was identified as steroid.
Potensi Senyawa Bioaktiv Spon Laut Axinella Carteri Asal Sumatera Barat Handayani, Dian
Jurnal Sains dan Teknologi Farmasi Vol 17 No 1 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

This paper reports the bioactivity potency of the marine sponge Axinella carteri, which has been investigated for its anticancer, antibacterial, antifungal and antiviral activities. This sponge is one of the most abudance organism in the coastline of West Sumatera. 
Uji Aktivitas Sitotoksik Ekstrak dan Fraksi dari Spon Laut Petrosia Sp dengan Metoda Brine Shrimp Lethality Test Krisyanella, Krisyanella; Handayani, Dian; unance, Lendra Y
Jurnal Sains dan Teknologi Farmasi Vol 16 No 2 (2011)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

Determination of cytotoxic activity of the extract and fraction of marine sponge Petrosia sp suing Brine Shrimp Lethality Test has been done. The Cytotoxic activity analysis was done toward methanol extract first, then continued to n-hexane, ethyl acetate and buthanol fractions respectively. The LC50 values were 70.736 ppm, 269.153 ppm, 197.38 ppm and 70.667 ppm respectively. Results showed that the extract and fraction of Petrosia sp potentially has cytotoxic activity whereas buthanol fraction has the higest citotoxic activity among at all. Phytochemistry screening for buthanol fraction contained terpenoid, steroid and saponin.
Validitas Estimasi Tinggi Badan berdasarkan Tinggi Lutut pada Lansia di Kota Malang (Validity of Height Estimation based on Knee Height in the Elderly in Malang) Nur Azkiyah, Wulan Sari; Handayani, Dian; -, Holipah
Indonesian Journal of Human Nutrition Vol 3, No 2 (2016)
Publisher : Jurusan Gizi, Fakultas Kedokteran, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.759 KB) | DOI: 10.21776/ub.ijhn.2016.003.02.5

Abstract

AbstrakPengukuran antropometri lansia pada dasarnya sama dengan usia lainnya, tetapi terkadang memerlukan cara yang berbeda untuk memberikan hasil yang lebih tepat karena perubahan fisiologi. WHO menekankan pentingnya persamaan yang tepat pada setiap negara dalam memprediksi tinggi badan lansia. Di Indonesia, beberapa studi mengenai persamaan tinggi lutut telah dilakukan, namun belum banyak dilakukan penerapannya untuk keakuratan pada suatu daerah. Analisis dari persamaan Chumlea I, Oktavianus, dan Fatmah kemungkinan akan menimbulkan hasil yang berbeda jika diterapkan di Kota Malang. Penelitian ini bertujuan untuk menganalisis validitas prediksi tinggi badan berdasarkan tinggi lutut menggunakan persamaan Chumlea I, Oktavianus, dan Fatmah serta merumuskan suatu model persamaan prediksi tinggi badan berdasarkan tinggi lutut pada lansia di Kota Malang. Penelitian cross sectional ini menggunakan 123 responden (69 laki-laki dan 54 perempuan) dengan usia 60-80 tahun yang dipilih dengan teknik purposive sampling. Kemudian peneliti melakukan perhitungan tinggi badan estimasi berdasarkan tinggi lutut menggunakan persamaan Chumlea I, Oktavianus, dan Fatmah. Hasil menunjukkan terdapat perbedaan antara rata-rata tinggi badan aktual dengan persamaan Chumlea I (p<0,05), Oktavianus (p<0,05), dan Fatmah (p<0,05), dengan korelasi yang sangat kuat (r>0,8). Ada perbedaan pada empat kelompok data, yaitu tinggi badan aktual, persamaan Chumlea I, Oktavianus, dan Fatmah pada laki-laki dan perempuan. Kesimpulan dari penelitian ini adalah ketiga persamaan tersebut cenderung bersifat overestimate. Dan persamaan baru yang dihasilkan dari penelitian ini tidak ada perbedaan rata-rata tinggi badan aktual dengan rata-rata estimasi tinggi badan menggunakan persamaan baru.Kata kunci: lansia, Persamaan Chumlea I,  Oktavianus,  Fatmah  AbstractAnthropometric measurement on elderly is principally the same as any other age measurements, but sometimes needs a different way to give more accurate results due to physiological changes. WHO emphasizes the importance of exact equation in each country in predicting the height of the elderly. In Indonesia, several studies on knee height equations have been conducted, but the accuracy of its application on a particular area has not been done much. The analysis of Chumlea I, Oktavianus, and Fatmah equations will likely lead to different results if applied in Malang. This study aimed to analyze the height predictive validity of knee height using the equations of Chumlea I, Oktavianus, and Fatmah and to formulate an equation model on height prediction based on knee height of the elderly in Malang. This cross-sectional study used 123 respondents (69 males and 54 females) aged 60-80 years old selected by purposive sampling. Then, the researchers conducted height estimation calculations based on knee height using Chumlea I, Oktavianus, and Fatmah equations. The results showed that there were differences between the average height of the actual equation of Chumlea I (p <0.05), Octavian (p <0.05), and Fatmah (p <0.05), with very strong correlations (r> 0.8). There were differences in the four groups of data, i.e. the actual height, equations of Chumlea I, Oktavianus, and Fatmah in men and women. This study concludes that those three equations tend to be overestimate. The new equation resulting from this study does not show differences in the actual average height and estimated average height.Keywords: elderly, Equation, Chumlea I, Oktavianus, Fatmah
Pengaruh Pemberian Tepung Daun Katuk terhadap Penebalan Dinding Aorta Tikus Wistar Callista, Olga; Handayani, Dian; Tritisari, Kanthi Permaningtyas
Indonesian Journal of Human Nutrition Vol 2, No 2 (2015)
Publisher : Jurusan Gizi, Fakultas Kedokteran, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.749 KB) | DOI: 10.21776/ub.ijhn.2015.002.02.3

Abstract

AbstrakKejadian aterosklerosis biasa diawali dengan cedera sel endotel yang menyebabkan peningkatan permeabilitas sel sehingga komponen plasma dapat masuk ke dalam dinding arteri, termasuk asam lemak. Akumulasi asam lemak dalam arteri dapat teroksidasi dan membentuk lapisan lemak di dinding arteri sehingga mengakibatkan penebalan dinding arteri dan penyempitan pembuluh darah. Salah satu terapi yang dapat mencegah peningkatan kadar lipid dalam darah adalah pemberian fitosterol. Daun katuk (Sauropus androgynus L. Merr) merupakan salah satu tanaman yang mengandung tinggi fitosterol. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian tepung daun katuk berbagai dosis terhadap penebalan dinding aorta tikus putih Wistar yang diberi diet aterogenik. Penelitian ini menggunakan rancangan acak lengkap dengan Post Test Control Group Design yang dilakukan pada 30 ekor tikus Wistar jantan. Sampel dibagi menjadi 5 kelompok, yaitu Kelompok Negatif (diet normal), Kelompok Positif (diet aterogenik), Kelompok P1, P2, dan P3 yang diberi diet aterogenik dengan substitusi tepung daun katuk 6%, 9%, dan 12%. Pemberian tepung daun katuk diberikan setiap hari secara peroral melalui pakan selama 60 hari. Parameter yang diukur adalah tebal dinding aorta. Hasil uji statistik menunjukkan tidak terdapat perbedaan yang signifikan antar kelompok (p>0,05). Dari penelitian ini disimpulkan bahwa pemberian tepung daun katuk belum memberikan pengaruh terhadap penurunan ketebalan dinding aorta, sehingga disarankan untuk meningkatkan jangka waktu intervensi penelitian.Kata kunci: penebalan dinding aorta, tepung daun katuk, diet aterogenik  AbstractAtherosclerosis usually begins with endothelial cell injury which causes increased cell permeability. This injury will affect plasma component so that it can get into the arteries wall, that includes fatty acids. Accumulation of fatty acids in arteries can be oxidized and forms a layer of fat in the arterial wall that leads to thickening of the artery walls and narrowing of blood vessels. One of the therapies that can prevent the elevation of plasma level is phytosterols therapy. Katuk leaf (Sauropus androgynus L. Merr) is a plant that contains high phytosterols. This study aims to determine the effect of various doses of katuk leaf powder on the aortic wall thickening of Wistar rats fed atherogenic diet. This study used a completely randomized design with post-test control group design on 30 male Wistar rats. The samples were divided into 5 groups, namely control negative group (normal diet), control positive group (atherogenic diet), P1, P2, and P3 groups were given atherogenic diet with katuk leaf powder substitution 6%, 9%, and 12% respectively. Katuk leaf powder was given orally every day for 60 days through feeding. The measured parameter was the aortic wall thickness. Statistical test results showed that there was no significant difference among the groups (p> 0.05). This study concludes that the administration of katuk leaf powder had no effects on decreasing the aortic wall thickness. Thus, it is advised to increase the duration of intervention.Keyword: aortic wall thickness, katuk leaf powder, atherogenic diet 
Densitas Energi dan Sajian Karbohidrat Makanan Tradisional dan Modern di Kota Malang (Energy Density and Carbohydrate Serving on Traditional and Modern Food in Malang) Handayani, Dian; Azizah, Nurrika; Setiyawan, Hanifa; Rahmawati, Widya
Indonesian Journal of Human Nutrition Vol 3, No 1 (2016)
Publisher : Jurusan Gizi, Fakultas Kedokteran, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (434.604 KB) | DOI: 10.21776/ub.ijhn.2016.003.01.2

Abstract

AbstrakObesitas dan diabetes mellitus merupakan masalah kesehatan yang berhubungan erat dengan asupan makanan terutama energi dan karbohidrat. Tingginya prevalensi obesitas dan diabetes mellitus di Jawa Timur, terutama di Kota Malang, tidak diimbangi dengan ketersediaan informasi tentang kandungan energi dan zat gizi pada makanan. Penelitian ini bertujuan untuk mengetahui perbedaan densitas energi dan sajian karbohidrat pada makanan tradisional dan modern di Kota Malang. Kandungan energi dan karbohidrat dalam tiap bahan makanan dianalisis menggunakan software Nutrisurvey. Densitas energi dihitung dengan menggunakan rumus perhitungan total energi pada makanan dibagi berat total makanan. Sajian karbohidrat dihitung dengan membagi total karbohidrat pada makanan dengan konstanta carbohydrate counting yaitu 15. Analisis statistik menggunakan SPSS 16 dengan independent t-test. Hasil penelitian ini menunjukkan bahwa densitas energi pada makanan modern secara signifikan lebih tinggi dibanding makanan tradisional (1,87 ± 0,63 vs 1,46 ± 0,43, p=0,004). Untuk sajian karbohidrat pada makanan modern dan tradisional tidak terdapat perbedaan yang signifikan (3,53 ± 2,28 vs 4,54 ± 2,28, p=0,093). Namun, terdapat tren bahwa sajian karbohidrat makanan tradisional lebih tinggi daripada makanan modern. Diharapkan hasil penelitian ini dapat menjadi informasi yang berharga bagi masyarakat.Kata kunci: Densitas energi, sajian karbohidrat, carbohydrate counting, makanan tradisional, makanan modern. AbstractObesity and diabetes mellitus are health problems related to food intake, especially energy and carbohydrates. The high prevalence of obesity and diabetes mellitus in East Java, even in Malang is not properly balanced with the availability of information about the energy and nutrient on food. This study aims to determine differences of energy density and carbohydrate served in traditional and modern food in Malang. Energy and carbohydrate content in each food material was analyzed using software Nutrisurvey. Energy density is calculated using the formula of calculating the total amount of energy in food divided by the total weight of the food. Carbohydrate serving is calculated by dividing the total carbohydrate on food with carbohydrate counting constant of 15. Statistical analysis used SPSS 16 with Independent T-Test. The results of this study show that the energy density in the modern food was significantly higher than that of traditional food (1,87±0,63 vs 1,46±0,43, p=0,004). There is no significant difference on carbohydrate serving between modern and traditional food (3,53±2,28 vs 4,54±2,28, p=0,093). But, the trend of carbohydrate serving shows that the traditional food is higher than modern food. It is expected that this research finding is highly valuable for it provides the information regarding food energy density and carbohydrate content for obese and diabetic patients.Keywords: Energy density, carbohydrate serving, carbohydrate counting, traditional food, modern food
HUBUNGAN ASUPAN MAGNESIUM DAN KADAR GLUKOSA DARAH PUASA PASIEN RAWAT JALAN DIABETES MELITUS TIPE 2 (CORRELATION BETWEEN MAGNESIUM INTAKE AND FASTING BLOOD GLUCOSE LEVEL IN OUTPATIENTS WITH TYPE 2 DIABETES MELLITUS) Faradhita, Anggun; Handayani, Dian; Kusumastuty, Inggita
Indonesian Journal of Human Nutrition Vol 1, No 2 (2014)
Publisher : Jurusan Gizi, Fakultas Kedokteran, Universitas Brawijaya Malang

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Abstract

Abstrak Pada Diabetes Melitus Tipe 2 terjadi resistensi insulin, dimana salah satu faktor yang dapat menyebabkan resistensi insulin adalah kurangnya asupan magnesium. Peran potensial magnesium dalam penyakit Diabetes Melitus adalah memperbaiki sensitifitas insulin. Beberapa penelitian terdahulu menunjukkan bahwa ada hubungan terbalik antara asupan magnesium dengan kejadian Diabetes Melitus Tipe 2. Penelitian ini bertujuan untuk menganalisis hubungan antara asupan magnesium dan kadar glukosa darah puasa pasien rawat jalan Diabetes Melitus Tipe 2 di RSUD Al-Ihsan Provinsi Jawa Barat. Desain dalam penelitian ini adalah Cross Sectional dengan jumlah responden 46 orang yang diambil secara purposive sampling. Pengumpulan data dilakukan bulan Juni-Juli tahun 2013 yang meliputi data umum, kebiasaan olahraga, status gizi, asupan energi, asupan magnesium, asupan protein, asupan serat dan data kadar glukosa darah puasa. Hasil penelitian menunjukkan bahwa ada hubungan yang bermakna antara asupan magnesium dan kadar glukosa darah puasa pasien (p < 0,001) dengan kekuatan korelasi sedang (r = -0,562), semakin tinggi asupan magnesium semakin rendah kadar glukosa darah puasa. Berdasarkan hasil penelitian ini, disarankan agar para penderita Diabetes Melitus mengkonsumsi magnesium dalam jumlah cukup serta mengatur pola makan yang baik dan berolahraga secara teratur sebagai langkah dalam pengendalian kadar glukosa darah. Kata Kunci: Asupan Magnesium, Kadar Glukosa Darah Puasa, Diabetes Melitus Tipe 2 AbstractDiabetes Mellitus type 2 reveals resistance insulin. Inadequate magnesium consumption has been reported to promote insulin resistance. The potential role of magnesium in Diabetes Mellitus is improving insulin sensitivity. Previous studies indicated that there is an inverse correlation between magnesium intakes and the incidence of type 2 Diabetes. This study aimed to analyze the association between magnesium intake and fasting blood glucose levels in outpatients with Type 2 Diabetes Mellitus in Al Ihsan Hospital. Cross-sectional study in 46 participants was taken by purposive sampling. Data collection was conducted in June-July 2013 which included common data, exercise habits, nutritional status, energy intake, magnesium intake, protein intake, fiber intake and fasting blood glucose levels. This research showed that there was a significant association between magnesium intake and fasting blood glucose levels of patients (p < 0.001) with a correlation of moderate strength (r = -0.562), high magnesium intake was followed by a decrease in fasting blood glucose levels. It is then suggested that people with diabetes mellitus consume adequate amounts of magnesium and set a good diet and regular exercise as a step in the control of blood glucose levels. Keywords: Magnesium Intake, Fasting Blood Glucose, Type 2 Diabetes Mellitus
PERBEDAAN METODE TEAM GAME TOURNAMENT DAN CERAMAH TERHADAP PENINGKATAN PENGETAHUAN PEMILIHAN JAJANAN SEHAT (THE DIFFERENCE BETWEEN TEAM GAME TOURNAMENT AND LECTURE IN INCREASING THE KNOWLEDGE OF CHOOSING HEALTHY SNACKS) Safitri, Cynthia Herdiana; Wilujeng, Catur Saptaning; Handayani, Dian
Indonesian Journal of Human Nutrition Vol 1, No 2 (2014)
Publisher : Jurusan Gizi, Fakultas Kedokteran, Universitas Brawijaya Malang

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Abstract

Abstrak Siswa sekolah dasar termasuk kelompok yang paling rentan menjadi korban dalam kasus keracunan makanan. Kejadian tersebut mencapai 17,26 – 25,15% kasus terjadi di lingkungan sekolah yaitu sebagian besar karena Pangan Jajanan Anak Sekolah (PJAS) tidak memenuhi syarat kesehatan. Ceramah merupakan metode dasar pembelajaran yang sering digunakan, namun cara ini terkadang membosankan karena responden cenderung lebih pasif, sedangkan bermain pada masa anak-anak merupakan sarana pendidikan yang penting untuk mengeksplorasi otak. Team Game Tournament (TGT) adalah salah satu metode pendidikan yang memadukan konsep pendidikan dengan kegiatan bermain. Tujuan dari penelitian ini adalah mengetahui perbedaan metode TGT dan ceramah terhadap peningkatan pengetahuan siswa kelas 5 SDN Tumpakrejo 1 dan SDN Tumpakrejo 2 kabupaten Malang tentang pemilihan jajanan sehat. Jenis penelitian ini adalah studi eksperimental, desain penelitian yang digunakan adalah quasy experimental study dengan pretest-posstest design. Metode sampling yang digunakan adalah total sampling dengan jumlah sampel sebesar 41 orang dari siswa kelas 5B SDN Tumpakrejo 1 dan siswa kelas 5 SDN Tumpakrejo 2. Variabel yang diteliti dan dianalisis pada responden tersebut adalah pengetahuan gizi terkait jajanan sehat pada kelompok ceramah dan kelompok TGT berdasarkan nilai pretest-posttest. Hasil penelitian menunjukkan bahwa terdapat perbedaan peningkatan pengetahuan yang signifikan antara kelompok TGT dan kelompok ceramah (p < 0,05). Peningkatan rata-rata nilai kelompok TGT lebih tinggi 2,93% dibandingkan kelompok ceramah. TGT dapat direkomendasikan sebagai metode pendidikan yang lebih sesuai untuk sasaran anak usia sekolah. Kata Kunci: Team game Tournament (TGT), Ceramah, Pengetahuan, Jajanan Sehat AbstractElementary school students is one of the most vulnerable groups to become victims food poisoning. The incidence occurring in the school environment reaches 17,26 to 25,15% cases, which was due to PJAS (snack for aged school children) not fulfilling the health requirements. Providing a Lecture is the basic learning method often used, but this method is occasionally boring due to passive respondents, while  playing in childhood is an important educational tool to explore brain. Team Game Tournament (TGT) is  one of the educational methods combining educationional concept and play activities. This study aims to determine the method differences of TGT and lectures to increase students’s knowledge of grade 5 students in SDN Tumpakrejo 1 and SDN Tumpakrejo 2 electoral district of Malang concerning healthy snacks. This research was an experimental study in which the research design was quasy experimental study with  pretest-posttest design. The sampling method in this research was 41 samples from grade 5 students in class B of SDN Tumpakrejo 1 and grade 5 students of SDN Tumpakrejo 2. The variables studied and analyzed in the respondents are nutritional knowledge concerning healthy snacks related to the lecture group and TGT group based on the value of the pretest and posttest. The results showed that there were significant differences between the increased knowledge of TGT group and lecture group (p<0.05), accounting for 2,93% higher average value in the former group. Team Game Tournament is then recommended as an educational method, more appropriate to target  school-aged children. Keywords: Team Game Tournament (TGT), Lecture , Knowledge, Healthy Snacks
Co-Authors . Dachriyanus . Yanwirasti Al-Rasyid, Harun Amri Bakhtiar Anggun Faradhita Anggun, Faradita Anis Mahmudah, Anis Armetristi, Fannisa Arwin Surbakti Aulani’ Am Ayuningtyas Dian Ariestiningsih Bambang Prijadi Calista, Rizky Ayu Diella Catur Saptaning Wilujeng Cynthia Herdiana Safitri Dhony, Ervia Fahma Dianika, Bani Djoko W. Soeadmadji Djoko Wahono Ekawati, Laily Ellen Ernesta B. Sappu Ellyza Nasrul Faradina, Daniar Septianing Fenti Mariska Yohana Fitria Iswari Fitria Rahmi Fransiska Imavike, Fransiska Galuh, Glaveria Hanifa Setiyawan, Hanifa Hayati, Yati Sri Hidayat Sujuti Holipah Holipah Inggita Kusumastuty Iva Tsalissavrina Kanthi Permaningtyas Tritisari, Kanthi Permaningtyas Kartika, Annisa Wuri Krisnawati, Hesthi Kristianingrum, Niko Dima Krisyanella Krisyanella Kumboyono Kumboyono Leny Budhi Harti M Asmadi M. Aris Widodo Mahyudin Mahyudin Martha Sririta Mery Sukmiwati Mieke Hemiawati Satari Mukhtar, M. Husni Munawaroh, Siti Mar'atul Muniro, Lailatul Nia Rochmawati Nindy Sabrina Novita Wijayanti Noviyandi Sayuti Nur Azkiyah, Wulan Sari Nurhablisyah Nurhayati, Happy Nurrika Azizah, Nurrika Olga Callista, Olga Pradina Purwati Puspa, Diah Puspita, Wita Hana Putri, Dianita Setya Pradita Rini Rita T Marpaung Rob W.M van Soest Rokhmah, Farida Dwi Rustini Rustini Sandehang, Cornelia Fransiska Sanusi Ibrahim Satya, Lega Shinta Anggraini, Shinta Siti Salmah Sri Andarini Suaida, Desi Holifatus Sudarmono, Andang Sumarah, Kristuti Catur Supratiwi, Ratih Indah Suryanto Suryanto Syafruddin Ilyas Tri Dewanti Widyaningsih unance, Lendra Y Utmi Arma, Utmi Veibiani, Nindita Arum Widya Rahmawati Yosfi Rahmi Yufri Aldi