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All Journal Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Endurance: Kajian Ilmiah Problema Kesehatan Journal of Midwifery Majalah Kedokteran Andalas UMI Medical Journal Andalas obstetrics and gynecology journal Jurnal Ilmu Keperawatan dan Kebidanan Jurnal Kesehatan Saintika Meditory
Andi Friadi
Universitas Andalas
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Diagnosis Prenatal Hidronefrose dengan Ultrasonografi (laporan kasus) YUSRAWATI, YUSRAWATI; FRIADI, ANDI
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 1, January 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (431.294 KB)

Abstract

Tujuan: Melaporkan 2 kasus hidronefrose yang didiagnosis dengan pemeriksaan USG pada masa prenatal. Hasil: Dua kasus hidronefrose yang didiagnosis dengan ultrasonografi. Kasus 1, hidronefrose didiagnosis pada usia kehamilan 32 - 33 minggu, didapatkan jenis kelamin perempuan dengan hidronefrose bilateral. Pada evaluasi postnatal dengan USG didapatkan kesan hidronefrose kanan moderat. Kasus 2, hidronefrose didiagnosis pada usia kehamilan 25 minggu, didapatkan jenis kelamin laki-laki dengan hidronefrose bilateral, megavesika dan oligohidramnion. Persalinan kedua kasus dengan bedah sesar pada kehamilan aterm. Bayi pertama normal. Bayi kedua menderita sindrom Potter dan meninggal setelah 7 jam karena pneumothorax. Kesimpulan: Kelainan yang mengenai ke dua ginjal (bilateral) lebih berbahaya dari pada kelainan yang mengenai satu ginjal (unilateral). [Maj Obstet Ginekol Indones 2007; 31-1: 42-8] Kata kunci: prenatal, hidronefrose, ultrasonografi
Recurrence-Free Survival Stage IB1-IIA2 Intermediate Risk Group (Based on Kartu Delgado) Cervical Carcinoma after Radical Surgery and Adjuvant Radiotherapy Friadi, Andi
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.542 KB) | DOI: 10.32771/inajog.v2i3.397

Abstract

Objective: To evaluate the benefits of adjuvant radiotherapy (ART) based on Kartu Delgado (simple form of Gynecologic Oncology Group (GOG) scoring system) aimed at women with early stage cervical cancer after radical surgery. Method: Fifty patients were enrolled for this study. Twenty one patients from 2011-2012 were given ART following surgery based on their Kartu Delgado score from as follows: score 120 were given ART. Their score and recurrence were compared with 29 patients who were treated in 2009-2010 (based on single prognostic factor). Result: We observed eighteen recurrences for the duration this study. Thirteen patients from the period of 2009-2010 and five patients from the period of 2011-2012. Most recurrences occurred in patients from 2009-2010 with score > 120 but were not designated ART. Two-years recurrence-free survival (RFS) for subjects with score 120 with ART was 64.29%. Conclusion: Adjuvant radiotherapy given based on Kartu Delgado reduced the number of recurrences in women with stage IB-IIA cervical cancer after treated by surgery. [Indones J Obstet Gynecol 2014; 3: 146-152] Keywords: cervical carcinoma, intermediate risk, prognostic factor, radical hysterectomy
Perbedaan Kadar Brain Derived Neurotropic Factor Neonatus Dari Ibu Hamil Normal Dan Anemia Defisiensi Besi Mardiah, Ainal; Amir, Arni; Friadi, Andi; Nasrul, Ellyza
Jurnal Endurance Vol 3, No 3 (2018): Jurnal Endurance: Kajian Ilmiah Problema Kesehatan
Publisher : Lembaga Layanan Pendidikan Tinggi (LLDIKTI) Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22216/jen.v3i3.3706

Abstract

Iron deficiency anemia is anemia caused by iron deficiency in the blood. Maternal iron deficiency affects the low iron reserves in neonates and it also influences on Brain Derived Neurotropic Factor (BDNF)  which affects cognitive function. The purpose of this study was to determine the difference mean of BDNF in neonates from normal pregnant women and pregnant women with iron deficiency. The design of this research was Cross Sectional design. This research was conducted in Community Health Center of Lubuk  Buaya, Ambacang Community Health Center, Community Health Center of Ikur Koto Health Center and Biomedical Laboratory of Andalas University on February 2017 to April 2018. There were 42 pregnant women was selected as sample e of this research. The samples were chosen by Consecutive Sampling. Then, the sample is divided into two groups: normal pregnant women and pregnant women with iron deficiency anemia. BDNF are examined by the ELISA. Next, the data were analyzed by using T test. The levels of BDNF neonates in normal pregnant group was 3.65(ng/ml) and the anemia pregnant group was 1.74(ng/ml) (p <0.05). There was significant difference of BDNF levels in neonates from normal pregnant women and pregnant women with iron deficiency anemia. The conclusion of this study is there is a difference of average BDNF in neonates from normal pregnant women and pregnant women with iron deficiency. Anemia defisiensi besi adalah anemia yang disebabkan karena kekurangan zat besi dalam darah. Defisiensi besi  maternal berdampak pada rendahnya cadangan besi pada neonatus dan berdampak terhadap ekspresi Brain Derived Neurotropic Factor (BDNF) yang berpengaruh pada fungsi kognitif. Tujuan penelitian ini adalah untuk mengetahui perbedaan rerata kadar BDNF pada neonatus dari ibu hamil normal dan ibu hamil defisiensi besi. Desain penelitian ini adalah Cross Sectional. Penelitian dilakukan di Puskesmas Lubuk Buaya, Puskesmas Ambacang, Puskesmas Ikur Koto dan Laboratorium Biomedik Universitas Andalas pada bulan Februari 2017 – Juli 2018. Sampel Penelitian adalah ibu hamil sebanyak 42 orang yang dipilih secara Consecutive Sampling, sampel dibagi menjadi dua kelompok yaitu ibu hamil normal dan ibu hamil anemia defisiensi besi. BDNF diperiksa dengan metode ELISA. Data dianalisa menggunakan uji T test. Kadar BDNF neonatus pada ibu kelompok normal adalah 3,65(ng/ml) dan kelompok ibu anemia adalah 1,74(ng/ml) (p<0,05). Terdapat perbedaan bermakna kadar BDNF pada neonatus dari ibu hamil normal dan ibu anemia defisiensi besi.
Recurrence-Free Survival Stage IB1-IIA2 Intermediate Risk Group (Based on Kartu Delgado) Cervical Carcinoma after Radical Surgery and Adjuvant Radiotherapy Friadi, Andi
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 3, July 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.542 KB) | DOI: 10.32771/inajog.v2i3.397

Abstract

Objective: To evaluate the benefits of adjuvant radiotherapy (ART) based on Kartu Delgado (simple form of Gynecologic Oncology Group (GOG) scoring system) aimed at women with early stage cervical cancer after radical surgery. Method: Fifty patients were enrolled for this study. Twenty one patients from 2011-2012 were given ART following surgery based on their Kartu Delgado score from as follows: score 120 were given ART. Their score and recurrence were compared with 29 patients who were treated in 2009-2010 (based on single prognostic factor). Result: We observed eighteen recurrences for the duration this study. Thirteen patients from the period of 2009-2010 and five patients from the period of 2011-2012. Most recurrences occurred in patients from 2009-2010 with score > 120 but were not designated ART. Two-years recurrence-free survival (RFS) for subjects with score 120 with ART was 64.29%. Conclusion: Adjuvant radiotherapy given based on Kartu Delgado reduced the number of recurrences in women with stage IB-IIA cervical cancer after treated by surgery. [Indones J Obstet Gynecol 2014; 3: 146-152] Keywords: cervical carcinoma, intermediate risk, prognostic factor, radical hysterectomy
HUBUNGAN KADAR KORTISOL DAN PROSTAGLANDIN MATERNAL DENGAN PERSALINAN PRETERM DAN ATERM Jesica, Fanny; Friadi, Andi
Jurnal Ilmu Keperawatan dan Kebidanan Vol 10, No 1 (2019): JURNAL ILMU KEPERAWATAN DAN KEBIDANAN
Publisher : STIKES Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/jikk.v10i1.540

Abstract

Penelitian ini merupakan penelitian Observasional dengan desain penelitian cross-sectional. Penelitian dilakukan di RSUD dr. Rasidin Padang, RSUD. Prof. Dr. MA Hanafiah SM Batusangkar, RSUP. M. Djamil, dan BPS. Nurhaida, Amd.Keb pada bulan September 2017 sampai Januari 2018. Jumlah sampel sebanyak 50 responden yang dipilih secara consecutive sampling yang dibagi menjadi 2 kelompok. Pemeriksaan kadar kortisol dan prostaglandin dilakukan di Laboratorium Biomedik Universitas Andalas Padang dengan metode ELISA. Terdapat hubungan bermakna antara kadar kortisol dengan persalinan preterm dan aterm (p= 0,02; p < 0,05). Terdapat hubungan kadar prostaglandin dengan persalinan preterm dan aterm (p = 0,023; p < 0,05). Terdapat hubungan kadar kortisol dengan prostaglandin pada aterm (p = 0,0001; p < 0,05). Tidak terdapat hubungan kortisol dan prostaglandin pada preterm (p = 0,52; p > 0,05). Kata Kunci: Kortisol, Prostaglandin, Persalinan Preterm
PENGARUH PAPARAN ASAP ROKOK TERHADAP KADAR ZINK DAN KORTISOL PADA TIKUS PUTIH HAMIL (RATTUS NORVEGICUS) Armalini, Rika; Friadi, Andi
Jurnal Ilmu Keperawatan dan Kebidanan Vol 10, No 1 (2019): JURNAL ILMU KEPERAWATAN DAN KEBIDANAN
Publisher : STIKES Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/jikk.v10i1.582

Abstract

Penelitian ini merupakan penelitian Eksperimen dengan desain penelitian post test only control group design Penelitian dilakukan di lab farmasi unand, pada bulan Juni sampai dengan agustus 2018. Pengambilan sampel dilakukan dengan simple random sampling (acak sederhana), Jumlah sampel sebanyak 28 ekor dibagi menjadi 4 kelompok, kelompok 1 sebagai kontrol penelitian, kelompok 2 diberikan perlakuan 1 batang rokok, kelompok 3 diberikan perlakuan 2 batang rokok dan kelompok 4 diberikan perlakuan 3 batang rokok. Pemeriksaan kadar zink dan kadar kortisol dilakukan di Laboratorium Biomedik Universitas Andalas Padang dengan metode ELISA. Tidak terdapat perbedaan bermakna antara paparan rokok dengan kadar zink (p= 0.32) maka, (p > 0,05). Dan tidak terdapat perbedaan paparan asap rokok dengan rerata kadar kortisol (p = 0,146) maka, ( p > 0,05). Kata Kunci: asap rokok, zink, kortisol
Update on the Diagnosis of Gestational Trophoblastic Disease Andi Friadi
UMI Medical Journal Vol 4 No 2 (2019): December 2019
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v4i2.68

Abstract

Penyakit trofoblas gestasional (PTG)/Gestational trophoblastic disease (GTD) terdiri dari kelompok mola hidatidosa yang terbagi menjadi komplit dan parsial, hingga kelompok Tumor trofoblas gestasional (TTG)/Gestational trophoblastic neoplasia (GTN) yang terdiri dari mola invasif, koriokarsinoma, dan placental site trophoblastic tumour/epithelioid trophoblastic tumour (PSTT/ETT). TTG dikategorikan menjadi dua yaitu yang tidak bermetastasis (hanya terbatas di uterus) dan yang bermetastasis (telah menyebar ke vagina, paru-paru atau otak). Penegakan diagnosis inisial PTG melalui pendekatan multimodalitas mencakup gejala klinis, kadar hCG dan pemeriksaan USG pelvis. Doppler membantu menilai angiogenesis dan karakterisitik neovaskularisasi PTG. Gambaran yang tampak pada USG akan menjelaskan gambaran pada histopatologinya. Pemeriksaan penunjang lain untuk PTG adalah rontgen thoraks, CT Scan dan MRI. Saat ini pemeriksaan imunohistokimia (IHK) dan polymerase chain reaction (PCR) sudah mulai digunakan untuk menentukan diagnosis PTG. Pemantauan hCG mempunyai peran penting dalam penatalaksanaan PTG. Tetapi karena terdapat beberapa pedoman yang menyatakan protokol berbeda-beda dalam pemantauan hCG, hal ini membuat para dokter spesialis obgin mempertanyakan mengenai pemantauan hCG pasca evakuasi. Himpunan Onkologi Ginekologi Indonesia mengeluarkan suatu Pedoman Nasional Pelayanan Kedokteran (PNPK) Tumor Trofoblas Gestasional yang didalamnya terkait diagnosis dan penatalaksaan TTG.
TUMOR GANAS OVARIUM RESIDIF METASTASIS KARSINOMA MUSIN KE UMBILIKUS, PERITONEUM, DAN CAIRAN ASITES TANPA DITEMUKAN TANDA KEGANASAN PADA PEMERIKSAAN HISTOPATOLOGIS PASCA OPERATIF SEBELUMNYA Arif Fadillah; Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 3, No 2 (2019)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.130-136.2019

Abstract

Background : Malignant ovarian tumor are still the number one cause of death and the second most  of incidents for gynecological malignant tumors. The principles of management of ovarian cancer are the same as the principles of handling other malignant diseases, for the treatment of primary lesions operatively and the handling of potential sites of tumor metastases with chemotherapy. Histopathological examination is still considered a gold standard for diagnosis and definitive treatment of malignant ovarian tumors. If histopathologic results are obtained, then the patient will be planned to undergo postoperative chemotherapy. The mismatch between the preoperative and intraoperative clinical features, and the results of postoperative histopathological examination is a problem in managing cases of ovarian malignant tumors.Objective : Report a case of residive ovarian carcinoma with no appearance of malignancy marker in the previous postoperative histopathological examination.Method : Case reportCase : We report the case of a 45-year-old woman with a history of two previous laparotomy. The first operation was carried out in February 2014 on the indication of an extra ovarian cyst, resulting in the impression of a "Follicular Cysts" based on histopathological examination. The second operation was performed in March 2015, performed surgical staging tumors with an indication of malignant ovarian tumors with clinical metastases, but from histopathological examination it was found that "Cystadenoma Ovarii Muscinosum Multiloculare" and "no visible signs of malignancy", so the patient was not managed with postoperative chemotherapy. In April 2019 patients came with complaints of new mass growth, from CT-Scan and USG investigations there was a suspicious impression of a residive ovarian tumor with metastases into the omentum and massive ascites. On May 16, 2019 an optimal debulking was performed with the findings of residive mass, ascites, and mass metastases in the intra operative peritoneum. From the results of histopathological examination, it was found that "Muscinous Carcinoma with metastases to the umbilicus, peritoneum, and ascitic fluidKeywords: Malignant residive ovarian tumor, mucinous ovarian carcinoma
Extra Gastrointestinal Stromal Tumor Pada Ovarium, Kasus Jarang Nana Liana; RZ Nizar; Aswiyanti Asri; Hera Novianti; Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 4, No 2 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.173-182.2020

Abstract

Objective : This article objective is to describe a woman with extra gastrointestinal stromal tumor (extra GIST) in ovary; Method : A case report and literature review; The author reports a woman 54 years old with complaints of swelling in the abdomen. Tumors suspected originate from ovary with an extension to abdominal wall. The patient had history of previous ovarian tumor surgery with pathological anatomy diagnosis was thecoma. Working diagnosis of the patient was residif ovarian malignancy and then suboptimal debulking was performed. Microscopically, ovarian tumors appear cellular and diffuse, partially arranged fascicles. Cells with rounded-spindle nuclei, mitosis ≥ 4 per 10 HPF. The conclusion was malignant thecoma which metastasizes to peritoneum and omentum. Differential diagnosis were GIST and leiomyosarcoma. Immunohistochemistry examination was performed with  Calretinin and CD117 to rule out the differential diagnosis. Calretinin were negative  and CD117 were strongly positively smeared. Based on the morphology and positive CD117 results, diagnosis was extra GIST of ovary.; Conclusion: Extra GIST in the ovary is an unusual location so that it can be misdiagnosed as a gynecological disorder. The differential diagnosis at this location is quite limited including thecoma, fibrothecoma and leiomyosarcoma.Keywords: extra gastrointestinal stromal tumor, ovary, thecoma
Malignant GIST DOG-1 Positif Pada Colon Dengan Metastasis Pada Jaringan Paraovarium Dan Cairan Asites Dini Andri Utami; Aswiyanti Asri; Hera Novianti; Andi Friadi
Andalas Obstetrics And Gynecology Journal Vol 4, No 2 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.183-193.2020

Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm of gastrointestinal tract that originate from Interstitial Cell of Cajal (ICC). The correct diagnosis of GISTs is important for therapeutic reasons of imatinib. Recently, DOG-1 has been introduced as an important diagnostic marker with high sensitivity and specificity. We report a caseof 40 years old woman with pain and swollen stomach in left lower quadrant since four month before come to the hospital. Ultrasound examination showed hipoechoic lession in the posterior of uterus and ascites. Paraovarian mass attached to the transverse colon and ascites was found on surgery. Histopathology diagnosis was a mesenchymal stromal tumour suggestive malignant GIST. Citological examination of asites fluid show a malignancy metastases. Immunohistochemistry showed negative for c-kit and positive for DOG-1, the conclusion is a GIST. Immunohistochemistry examinations are important to make defenitive diagnosis for GIST.  C-kit-negative GIST sare still rare, but defenitive diagnosis must be made because related to target therapy. DOG 1 has been proven in 89% of c-kit-negative GIST and claimed more sensitive and spesific.Keywords: GIST, c-kit, DOG-1, ICC, paraovary
Co-Authors Aisah Djumadisstsaniah Angga Trifianda Prima Arif Fadillah Armalini, Rika Arni Amir Aswiyanti Asri Bambang Sutrisna Budiningsih Siregar Defrin Defrin Dini Andri Utami Ellyza Nasrul Fanny Jesica Frita Dwi Luhuria Hafni Bacthiar Harridhil Silmi Hera Novianti Ilmiawati, Ilmiawati Jesica, Fanny Lisa Ernita Lisma Evareny Mardiah, Ainal Nana Liana Rika Armalini RZ Nizar Sigit Purbadi Tia Reza Widayat Widayat Yusrawati Yusrawati Yussya Aulia Malik