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All Journal Jurnal Medika Veterinaria JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Jurnal Ilmiah Mahasiswa Veteriner Jurnal Natural The International Journal of Tropical Veterinary and Biomedical Research
Rinidar Rinidar
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Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Energy Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Physics Public Health Veterinary

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8. The Total of Leukocytes Mice (Mus musculus) Exposed To Secondhand Smoke Extract And Given Watermelon (Citrullus vulgaris) Dewi Mauliza; Rusli Rusli; Roslizawaty Roslizawaty; Rosmaidar Rosmaidar; Rinidar Rinidar; Dian Masyitha
Jurnal Medika Veterinaria Vol 12, No 1 (2018): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.294 KB) | DOI: 10.21157/j.med.vet..v12i1.4269

Abstract

This study aimed to determine the effect of the red watermelon extract can affect the number of leukocytes in mice exposed to cigarette smoke. This study was designed with a completely randomized design using a unidirectional pattern 20 male mice (Mus muscullus) were divided into 4 groups. K1 negative controls were given 0.5 ml of distilled water, K2 positive control by exposure to cigarette smoke and 0.5 ml of distilled water, K3 by exposure to cigarette smoke and red watermelon extract were given a dose of 22 mg / mouse and K4 by exposure to cigarette smoke and were given extracts of red watermelon a dose of 44 mg / mouse. Exposure to cigarette smoke and red watermelon extract conducted for 30 days, making blood on day 31. Blood sampling performed at Plexus Retroorbitalis. Furthermore, counting the number of leukocytes. Data were analyzed using ANOVA completely randomized design with SPSS for Windows 16.0. The results of this study showed that the extract of watermelon for 30 days showed their real influence (P 0.05) to the number of leukocytes in mice. It is concluded that free radicals contained in cigarette can cause a leukocytosis, an inflammatory, oxidative stress and red watermelon extract can minimize cell damage.
4. The Value of Erythrocytes, Hemoglobin, and Hematocrit of Mice (Mus musculus) Exposed to Cigarette Smoke and Given Red Watermelon Extract (Citrullus vulgaris) Yola Heryanita; Rusli Rusli; Rosmaidar Rosmaidar; Zuraidawati Zuraidawati; Rinidar Rinidar; Nuzul Asmilia; Muhammad Jalaluddin
Jurnal Medika Veterinaria Vol 12, No 1 (2018): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (502.977 KB) | DOI: 10.21157/j.med.vet..v12i1.4106

Abstract

The aim of this research was to investigate the effect of red watermelon (Citrullus vulgaris) extract to the value of erythrocytes, hemoglobin, and hematocrit of mice (Mus muscullus) exposed to cigarette smoke. This study followed direct complete randomized design by using 12 males’ mice which divided into 4 groups. The treatment group is divided by the negative control group which given 0,5 ml of aquadest, the positive control group which exposed to cigarette smoke and 0,5 ml of aquadest. The treatment group I was exposed to cigarette smoke and given red watermelon extract dose 22 mg/Bw mice. The treatment group II was exposed to cigarette smoke and given red with watermelon extract dose 44 mg/Bw mice. The exposure to cigarette smoke and the given of red watermelon extract were conducted for 30 days. The blood taking was performed on day 31 in the Plexus retroorbital.  Furthermore, the number of erythrocytes, hemoglobin and hematocrit were calculated. The data were analyzed using ANOVA completely randomized design with SPSS for Windows 16.0. The results of this study showed that the extract of red watermelon for 30 days showed a highly significant effect (P 0.01) to the number of erythrocytes, hemoglobin, and hematocrit of mice. It is concluded that free radicals contained in the cigarette can cause a hemoglobin desaturation, increased blood viscosity, oxidative stress and red watermelon extract can minimize the damage.
14. The Potency of Sernai (Wedelia biflora) Leaf N-hexan Extract as Analgesic Compared to Ibuprofen on Mice (Mus musculus) Zulkarnaini Zulkarnaini; Rinidar Rinidar; Rosmaidar Rosmaidar; T. Armansyah TR; Abdul Harris; Muhammad Isa
Jurnal Medika Veterinaria Vol 12, No 2 (2018): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (499.788 KB) | DOI: 10.21157/j.med.vet..v12i2.4144

Abstract

This study aimed to determine the analgesic potential of sernai leaves n-Hexan extract on 24 male mice, aged 2-3 month with 20-25 g weighed. This study used split-plot design consisted of 6 groups. P0 as negative control was given aquades and P1 as positive control was given ibuprofen (10 mg/kg Body Weight). Treatment groups including P2, P3, P4, and P5 were given n-Hexan extract of sernai leaves with dosage of 15, 30, 45, and 60 mg/kgBW, respectively. Pain assessment was conducted using Hot Plate method. Observation of mice behaviour including licking it's front and back leg, or by jumping. This study showed there was significant difference (P0,05) between dosage and time. Duncan’s test showed P1 was significantly different (P0,05) from P2, but P3 and P5 were not significantly different from P1. P3 and P4 were significantly different (P0,05) from P2 and not significantly different from P1, while P5 was not significantly different from P3 and significantly different from P1. We can conclude that dosage of 30 and 45 mg/kgBW of n-Hexan extract of sernai leaves had analgesic potential on mice, and 60 mg/kgBW was comparable to ibuprofen as pain relieve in mice
16. The Number Of Leukocyte And Leukocyte Differential In Broilers That Infected With Eimeria tenella And Given Neem Leaf Extract And Jaloh Extract Rizki Aulia; Sugito Sugito; M. Hasan; T. Fadrial Karmil; Gholib Gholib; Rinidar Rinidar
Jurnal Medika Veterinaria Vol 11, No 2 (2017): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (253.49 KB) | DOI: 10.21157/j.med.vet..v11i2.4667

Abstract

The aim of this research was to determine the effect of giving neem leaf extract combined with jaloh towards the total of leukocytes and differential leukocyte in broilers that was infected with Eimeria tenella. This research samples were 20 Cobb stain broilers 14 days old. Design the research was complete randomized design with five treatments and each treatment consists of four repetitions. First treatment (P1) as negative control which was only given mineral water; second treatment (P2) as positive control was is given 5 mg/L anti-stress commercial in drinking water; Third treatment (P3) was given 1000 mg/L Jaloh extract; Fourth treatment (P4)was given 250mg/L neem extract; and fifth treatment (P5)was given 1000mg/L jaloh extract combined with 250mg/L neem extract. Anti-stress commercial and extract treatment dissolved in drinking water. The treatment start from 08.00 until 18.00 for ten days. Next in the 11th day (chicken 25 days old)was inoculated Eimeria tanella sporulatif as much as 1 x 104 ookista/ml orally. Then the blood was taken sampling when the chicken 30 days old (five days after infected). Blood sampling was done in the brachial vein. Furthermore, the number of leukocytes and differential leukocyte.Was calculated data were analyzed using complete randomized design with the help of SPSS for Windows 1.8 program. The result of this research showed that giving jaloh and neem leaf extract were not giving significant effect (P0,05) towards the number of leukocyte as well as differential leukocyte of broilers that was infected with Eimeria tenella. The conclusion of this research were giving jaloh leaf extract and neem for 10 days was not giving significant effect towards number of leukocytes and differential leukocyte broilers that infected with Eimeria tenella
15. Potency of Methanolic Extract of Sernai Stems (Wedelia biflora) as Analgesic on Mice (Mus musculus) Annisa Rizka Rahmatia; Rinidar Rinidar; T. Armansyah TR; Rosmaidar Rosmaidar; Abdul Harris; Yudha Fahrimal
Jurnal Medika Veterinaria Vol 12, No 2 (2018): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (582.321 KB) | DOI: 10.21157/j.med.vet..v12i2.4230

Abstract

The purpose of this research was to determine the potency of methanolic extract of sernai stem (Wedelia bilflora) as analgesic to mice (Mus muculus) compared to ibuprofen. This research use split-plot method with 5 treatments and 5 replications. Group P0 as negative control was given aquadest, P1 as positive control was given ibuprofen, while P2, P3, and P4 were given the extract with dosage of 40, 50, and 60 mg/kg bw, respectively. The pain analysis of mice was conducted using hotplate method and the observation was carried out at 0 minute, 30 minutes, 60 minutes, 90 minutes, and 120 minutes. The data was analyzed using analysis of varians (Anova) followed by Duncan’s test. The results of this research showed  that P1, P2, P3 and P4 had significant difference (P0,05) from P0. P1 did not have significant  difference (P0,05) from P2 but it was different from P3 and P4 (P0,05). From this result we can conclude that methanolic extract of sernai stem was potential as analgesic, dosage of 40 mg/kg bw was equal to ibuprofen, while 50 mg/kg bw and 60 mg/kg bw showed better effect than ibuprofen.
4. Study of Knowledge, Attitude and Action of Buffalo Ranchers in the VillagesAround Nagan Raya Power Plant on the Impact of Fly Ash Exposure Ira Susanti; Rinidar Rinidar; Sugito Sugito
Jurnal Medika Veterinaria Vol 14, No 1 (2020): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v14i1.11158

Abstract

One of the biggest contributors to air pollution is the production of coal fly-ash from the power plant industry. Fly-ash has an immediate impact on human and animal health around the power plant. Many buffaloes are maintained by Nagan Raya people and are often consumed by the community. The buffalo ranchers in this area release their livestock around the 110 MW Steam Power Plant that using low-rank coal. This ranchers’s behavior raises concerns about buffalo health due to exposure to fly ash. This study aims to examine the relationship between knowledge, attitude, and action of buffalo ranchers to the impact of fly ash exposure on the buffalo they maintain. This research used a cross-sectional design. The research time was done in February 2018 by taking 30 samples as respondents in four villages around Nagan Raya Power Plant. The tools used to assess knowledge, attitudes, and actions were using questionnaires. Data were analyzed statistically with the Chi-Square Test through SPSS for Windows version 17.0. The results showed that there was no significant relationship between the knowledge of buffalo ranchers and the impact of fly-ash exposure (P 0.05) while the attitude and actions of buffalo ranchers had a significant relationship with the impact of fly-ash exposure (P 0.05, P 0 , 05). These results conclude that the buffalo ranchers in the villages around the plant have not understood the impact of fly-ash arising from coal in the Nagan Raya power plant. It is expected that the relevant parties to conduct counseling about the impact of fly-ash exposure and the way of good buffalo management.
Efek Pemberian Ekstrak Kulit Pisang Kepok Terhadap Kadar Glukosa Darah Tikus Putih Yang Diinduksi Diet Tinggi Lemak Siti Prawitasari Br. Hasibuan; Muslim Akmal; Sugito Sugito; Teuku Zahrial Helmi; Rinidar Rinidar; Lian Varis Riandi
JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Vol 7, No 1 (2021): APRIL 2021
Publisher : Universitas Ubudiyah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33143/jhtm.v7i1.1483

Abstract

ABSTRAKDiabetes melitus merupakan penyakit yang disebabkan oleh kekurangan atau ketidakefektifan pankreas memproduksi insulin sehingga kadar glukosa  di dalam darah meningkat atau menurun. Penelitian ini dilakukan untuk melihat pengaruh pemberian ekstrak kulit pisang kepok terhadap penurunan kadar glukosa darah tikus putih yang diinduksi diet tinggi lemak. Dua puluh lima tikus putih dibagi menjadi 5 kelompok perlakuan. Kelompok K1 adalah kelompok tikus yang diberikan pakan standar. Kelompok K2 adalah kelompok tikus yang diberikan pakan 7 mg diet tinggi lemak. Kelompok K3 adalah kelompok tikus yang diberikan 7 mg diet tinggi lemak dan pemberian glibenklamid 0,126 mg/200g berat badan. Kelompok K4 dan K5 adalah kelompok tikus yang diberikan 7 mg diet tinggi lemak dan ekstrak kulit pisang kepok masing-masing dengan dosis 100 mg/kgbb dan 200 mg/kgbb. Masing-masing perlakuan dilakukan selama 60 hari, pada hari ke 61 dilakukan pengambilan darah melalui jantung untuk melihat kadar glukosa darah dengan alat biochemical analyzer veteriner. Hasil penelitian terhadap kadar glukosa darah menunjukkan bahwa pemberian ekstrak kulit pisang kepok 100 mg/kgbb dapat menurunkan kadar glukosa darah pada keadaan normal. Kata kunci: Diet tinggi lemak; ekstrak kulit pisang kepok; kadar glukosa darah 
CEMARAN LOGAM BERAT TIMBAL (PB) PADA INSANG IKAN CENDRO (Tylosurus crocodilus) DI PESISIR KRUENG RAYA KABUPATEN ACEH BESAR Diana Nasrun; Rinidar Rinidar; T. Armansyah TR
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 3 (2017): MEI - JULI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (417.403 KB) | DOI: 10.21157/jim vet..v1i3.3273

Abstract

Penelitian ini bertujuan mengidentifikasi cemaran logam berat timbal (Pb) pada insang ikan cendro (Tylosurus crocodilus) di pesisir Krueng Raya Aceh Besar. Sampel dalam penelitian ini adalah ikan cendro yang diperoleh langsung dari tempat penjualan ikan di Desa Lamnga Kecamatan Mesjid Raya Kabupaten Aceh Besar. Sebanyak 9 ekor ikan dibagi atas 3 kelompok dan 3 ulangan menurut ukuran tubuh, yaitu ikan cendro kecil dengan bobot 500 g (P1), ikan cendro sedang dengan bobot 500-1000 g (P2), dan ikan cendro besar dengan bobot 1000 g (P3). Prosedur pengujian logam berat timbal mengacu pada SNI 2354.5-2011 dan diperiksa menggunakan alat Atomic Absorption Spectrophotometer (AAS). Hasil uji memperlihatkan rata-rata (±SD) konsentrasi Pb pada insang ikan cendro yaitu (P1) (-0,2038±0.09), (P2) (-0,2148±0.11) dan (P3) (-0,1681±0.12). Berdasarkan batas deteksi alat uji dari Laboratorium Balai Riset dan Standardisasi Industri menunjukkan bahwa kadar Pb dari masing-masing bobot ikan adalah 0,0001 mg/kg. Disimpulkan bahwa hasil pengujian konsentrasi Pb pada ikan cendro masih di bawah nilai batas ambang baku Pb pada ikan.
PENGARUH EKSTRAK ETANOL DAUN JAMBLANG (Syzygium cumini (L.) SKEELS) TERHADAPT GLUKOSA DARAH PADA TIKUS PUTIH (Rattus norvegicus) DIABETES MELLITUS YANG DIINDUKSI STREPTOZOTOSIN Delvy Yuana Mustika; Zuhrawaty NA; Abdul Harris; Rinidar Rinidar; Nuzul Asmilia; Muhammad Hasan
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 4 (2017): AGUSTUS-OKTOBER
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.906 KB) | DOI: 10.21157/jim vet..v1i4.4349

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol daun jamblang terhadap kadar glukosa darah pada tikus putih diabetes mellitus yang diinduksi Streptozotosin (STZ). Hewan coba yang digunakan adalah 15 ekor tikus putih jantan dengan berat badan 200-250g. Tikus secara acak dibagi menjadi 5 kelompok perlakuan masing-masing terdiri dari 3 ekor. Kelompok control negatif  (KN) tidak diinjeksi STZ dan tidak diberi Ekstrak Etanol Daun Jamblang (EEDJ), kelompok control positif (KP) diinjeksi STZ 40 mg/kg BB dan tidak diberi EEDJ, kelompok P1, P2, dan P3 diinjeksi STZ 40 mg/kg BB dan diberi EEDJ dengan dosis masing-masing 100 mg/kg BB, 150 mg/kg BB dan 200 mg/kg BB. Pemberian EEDJ diberikan secara oral selama 14 hari. Penelitian ini menggunakan metode Rancangan Acak Lengkap pola searah. Hasil analisis varian menunjukkan bahwa perlakuan pemberian EEDJ berpengaruh sangat nyata (P0,01) terhadap penurunan kadar glukosa darah tikus. Rata-rata kadar glukosa darah tikus kelompok KN (110,33±8,38 mg/dL), KP (448,00±40,33 mg/dL), P1 (100,00±8,34 mg/dL), P2 (103,33±5,68 mg/dL) dan P3 (92,00±6,08 mg/dL). Dari hasil penelitian dapat disimpulkan bahwa pemberian EEDJ dapat menurunkan kadar glukosa darah tikus putih jantan diabetes mellitus yang diinduksi STZ. Dosis EEDJ yang efektif untuk menurunkan kadar glukosa darah adalah 200 mg/kg BB.
Daya Hambat Ekstrak Etanol Daun Mengkudu (Morinda Citrifolia L.) Terhadap Pertumbuhan Salmonella Sp. Dan Escherichia Coli (Inhibition Effect Of Ethanol Extract Of Noni Leaf (Morinda Citrifolia L.) On The Growth Of Salmonella Sp. And Escherichia coli) Devy Kartika Hadi; Erina Erina; Rinidar Rinidar; Fakhrurrazi Fakhrurrazi; Rasmaidar Rasmaidar; Arman Sayuthi
JURNAL ILMIAH MAHASISWA VETERINER Vol 3, No 2 (2019): FEBRUARI-APRIL
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (645.773 KB) | DOI: 10.21157/jim vet..v3i2.10835

Abstract

ABSTRAKPenelitian ini bertujuan mengetahui kepekaan ekstrak daun mengkudu (Morinda citrifolia L.) terhadap pertumbuhan Salmonella sp. dan Escherichia coli Esktrak daun mengkudu dibagi menjadi 3 konsentrasi yang berbeda yaitu 25%, 50%, 75%. Uji daya hambat dilakukan sesuai dengan metode Kirby-Bauer. Hasil rata-rata zona hambat ekstrak daun mengkudu terhadap bakteri Salmonella sp. pada konsentrasi 25% yaitu 6,2 mm, pada konsentrasi 50% yaitu 7,1 mm, dan pada konsentrasi 75% diperoleh rata-rata 6,6 mm. Zona hambat ekstrak daun pandan wangi terhadap Escherichia coli pada konsentrasi 25% rata-rata 7,3 mm, pada konsentrasi 50% 7,2 mm dan pada konsentrasi 75% diperoleh rata-rata 7,5 mm. Kontrol positif antibiotik amphicilin terhadap bakteri Salmonella sp. didapatkan rata-rata 6,2 mm, sedangkan terhadap bakteri Escherichia coli dengan rata-rata 19,6 mm. Berdasarkan penelitian ini dapat disimpulkan bahwa ekstrak daun mengkudu memiliki daya yang lemah dalam menghambat pertumbuhan Salmonella sp. dan Escherichia coli.Kata kunci: daya hambat, ekstrak daun mengkudu, Salmonella sp. dan Escherichia coli. ABSTRACTThe aims of this research is to know the sensitivity of noni leaf extract (Morinda citrifolia L.) against Salmonella sp. and Escherichia coli. Noni leaf extract was divided into 3 different concentrations 25%, 50%, 75%. The inhibition effect test was performed in accordance to Kirby-Bauer method. The average of inhibition zone of noni leaf extract on Salmonella sp. at 25% concentration was 6.2 mm, at concentration of 50% was 7.1 mm, and at concentration 75% obtained average 6.6 mm. The average inhibition zone of noni leaf extract againts Escherichia coli at 25% concentration was 7.3 mm, at concentrations of 50% was 7.2 mm and at concentration of 75% obtained an average of 7.5 mm. The averaged positive control of ampicillin antibiotics against Salmonella sp. was 6.2 mm, while against Escherichia coli was 19.6 mm. Base on this research it can be concluded that the noni leaf extract had weak activity to inhibit the growth of Salmonella sp. end Escherichia coli.Keyword : inhibition effect, noni leaf extract, Salmonella sp. and Escherichia coli.
Co-Authors Abd. Rasyid Syamsuri Abdul Harris Abdullah Azmi Harahap Abdullah Hamzah Annisa Rizka Rahmatia Arman Sayuthi Darmawi Darmawi Dasrul Dasrul Delvy Yuana Mustika Desi Ramadhani Devy Kartika Hadi Dewi Mauliza Dian Masyitha Diana Nasrun Erdiansyah Rahmi Erdiansyah Rahmi Erina Erina Fakhrurrazi Fakhrurrazi Fitri Wulan Sari Gholib Gholib Hamdan Hamdan I Gusti Wayan Murjana Yasa Ira Susanti Juli Melia Lian Varis Riandi M Daud AK M Hasan M. Hasan Mahdi Abrar Muhammad Hasan Muhammad Isa Muhammad Jalaluddin Muhammad Nur Salim Muslim Akmal Nafsul Muthmainnah A NURLIANA NURLIANA Nuzul Asmilia Rasmaidar Rasmaidar Razali Razali Rizki Aulia Roslizawaty Roslizawaty Rosmaidar Rosmaidar Safika S, Safika Siti Hajar Siti Prawitasari Br. Hasibuan Sonya Tri Wahyuni Sugito Sugito Sugito Sugito Susy Sriwahyuni T Zahrial Helmi T. Armansyah TR T. Fadrial Karmil Teuku Reza Ferasyi Teuku Zahrial Helmi Tongku N Siregar Vara Tassa Sutari Wenny Novita Sari Yandi Syahputra Yola Heryanita Yudha Fahrimal Zuhrawaty NA Zuraidawati Zuraidawati