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All Journal Jurnal Veteriner Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Jurnal Farmasi Klinik Indonesia Global Medical and Health Communication Indonesian Journal of Science and Technology Paediatrica Indonesiana Indonesian Journal of Rheumatology Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Jurnal Kedokteran Hewan

Mohammad Ghozali

Universitas Padjadjaran

Author-ID : 2760898

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Veterinary

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Tingkat Pengetahuan Peternak Kambing Perah Terhadap Penyakit Zoonosis Studi kasus “Kelompok Tani ternak Sympay Tampomas” Cimalaka Tyagita Hartady; Rini Widyastuti; Mohammad Ghozali
Dharmakarya Vol 7, No 3 (2018): September
Publisher : Universitas Padjadjaran

Hubungan antara peternak, hewan ternak, dan lingkungan sangat signifikan sehingga diperlukan studi untuk dapat mengetahui hubungan ketiga komponen tersebut terhadap penyakit zoonosis. Kegiatan diawali dengan menilai keadaan umum lingkungan peternakan dan kondisi kambing perah melalui tanya jawab berbagai faktor risiko timbulnya penyakit zoonosis, penyuluhan kepada peternak mengenai penyakit-penyakit yang umum menyerang kambing perah dan pentingnya pengelolaan kesehatan kambing perah. Sebanyak 75% peternak telah membuat kandang kambing dengan model panggung, beralas bambu, serta memiliki kisi-kisi di dindingnya untuk memudahkan perputaran udara, 25% kandang lainnya dibuat dengan model terbuka dan kambing langsung kontak dengan lantai. Jarak antar kandang di daerah ini umumnya tidak saling berdekatan. Di sisi lain, sejumlah 16,7 % peternak merupakan kelompok peternak berumur lebih dari 47 tahun dan beresiko tinggi terhadap infeksi penyakit. Sedangkan 16,7% peternak mengerti tentang penyakit zoonosis dari kambing ke manusia didukung dengan rendahnya upaya peternak dalam melakukan tindakan pencegahan terhadap infeksi zoonosis. Sebanyak 83,3% peternak cenderung tidak melakukan pencegahan terjadinya penyakit zoonosis. Mengenai perawatan kesehatan kambing, rata-rata 48% peternak tidak melakukan tindakan-tindakan pencegahan penyakit infeksi pada kambingnya. Kondisi ini berpotensi menyebabkan kambing terjangkit penyakit dan tidak menutup kemungkinan menular ke ternak lainnya atau ke peternak.

Tingkat Pengetahuan dan Respon Peternak Kambing Perah terhadap Penyakit Hewan Studi Kasus: Kelompok Tani “Simpay Tampomas” Cimalaka, Sumedang Rini Widyastuti; Dwi Wahyudha Wira; Mohammad Ghozali; Kikin Winangun; Mas Rizky Anggun Adipurna Syamsunarno
Dharmakarya Vol 6, No 2 (2017): Juni
Publisher : Universitas Padjadjaran

Peternakan kambing perah merupakan mata pencaharian utama masyarakat Kecapatan Cimalaka, Kabupaten Sumedang. Pengelolaan peternakan masih dilakukan dengan cara tradisiona, sehingga perlu dilakukan upaya peningkatkan pengetahuan kelompok peternak kambing perah mengenai pengelolaan manajemen kesehatan kambing perah serta mencegah terjadinya kerugian akibat dampak penyakit. Salah satunya adalah melalui kegiatan penyuluhan mengenai penyakit-penyakit pada ternak terutama dari aspek klinis. Kegiatan diawali dengan survei lokasi, pemberian vitamin pada kambing perah, penyuluhan, pengisian kuesioner, pengolahan hasil kuesioner. Pada tahap akhir, dilakukan timbal balik (feedback) pada peternak atas hasil yang didapatkan dari pengobatan dan kuesioner. Hasil menunjukkan bahwa tangka pengetahuan peternak terhadap penyakit hewan dan cara pencegahannya sudah cukup baik. Kasus yang banyak berkembang di daerahpeternakan tersebut adalh Scabies, mastitis dan Bloat dengan gejala umum berkurangnya nafsu makan dan demam. Peternak biasanya memberikan pertolongan pertama dengan memberikan air asam dan obat cacing. Berdasarkan hasil tersebut, dapat bahwa peternak telah memiliki tingkatpengetahuan penyakit yang baik tetapi belum memiliki pengetahuan untuk penangann penyakit secara memadai.

Acute Iron Dextran Injection Increases Liver Weight and Reduces Glycerol Kinase Expression in Liver Ramdan Panigoro; Fadhal M. Ahmad; Uni Gamayani; Neni Anggraeni; Rini Widyastuti; Mohammad Ghozali; Mas Rizky A.A Syamsunarno
Indonesian Journal of Clinical Pharmacy Vol 7, No 4 (2018)
Publisher : Universitas Padjadjaran

Iron is essential and needed in a very small amount. When iron exceeds normal need, metabolic alteration occurs, causing hepatosteatosis. The mechanism of iron inducing hepatosteatosis remains unclear. Glycerol kinase, the enzyme responsible in triglyceride synthesis initiation, is assumed to have a role in the pathomechanism of hepatosteatosis. This study aimed to investigate the gene expression of glycerol kinase in an acute iron overload condition. This study was conducted in Animal Laboratory Faculty of Medicine and Central Laboratory Universitas Padjadjaran from May to June 2017. Three groups of mice were divided by the dose of iron dextran injection (0, 0.1, 0.3 mg/day/mice). After 19 days, mice were terminated, liver weight was measured and glycerol kinase gene expression in the liver was determined by semi-qualitative PCR. Quantification of PCR result was calculated by ImageJ software. There was a significant change in liver weight of the mice in a dose-dependent manner of iron injection. The expression of glycerol kinase tended to decrease, but statistically insignificant. Acute iron dextran injection increases liver weight and tends to reduce glycerol kinase gene expression in mice liver.Keywords: Glycerol kinase, hepatosteatosis, iron overload Efek Zat Besi Dosis Tinggi Akut dalam Meningkatkan Berat Organ dan Menurunkan Ekspresi Gliserol Kinase HeparAbstrakZat besi merupakan nutrien esensial dan diperlukan dalam jumlah yang sangat kecil. Ketika kadar zat besi melebihi kadar normal dalam tubuh, terjadi perubahan metabolisme yang menyebabkan hepatosteatosis. Mekanisme zat besi dalam menyebabkan hepatosteatosis masih belum diketahui secara pasti. Gliserol kinase, enzim yang menginisiasi sintesis trigliserida, diduga berperan dalam patomekanisme hepatosteatosis. Penelitian ini bertujuan untuk meneliti ekspresi gen gliserol kinase pada hepar pada kondisi tinggi zat besi akut. Penelitian ini dilakukan di Laboratorium Hewan Fakultas Kedokteran dan Laboratorium Sentral Universitas Padjadjaran dari bulan Mei sampai dengan Juni 2017. Tiga kelompok mencit dibagi berdasarkan dosis injeksi iron dextran intraperitoneal (0, 0,1, 0,3 mg/hari/ekor). Setelah 19 hari, mencit diterminasi, berat hepar ditimbang dan ekspresi gen gliserol kinase diukur dengan metode semi-kualitatif PCR. Kuantifikasi hasil PCR dilakukan dengan menggunakan aplikasi ImageJ. Terdapat peningkatan berat hepar secara signifikan yang sejalan dengan dosis ijeksi zat besi. Ekspresi gen gliserol kinase cenderung menurun, meskipun secara statistik tidak signifikan. Keadaan tinggi kadar zat besi yang akut meningkatkan berat hepar dan cenderung menurunkan ekspresi gen gliserol kinase pada hepar mencit.Kata kunci: Gliserol kinase, hepatosteatosis, zat besi berlebih

Anemia and Eosinophilia in Traditional Goat Farmers: Early Markers of Strongyle Zoonoses (ANEMIA DAN EOSINOFILIA PADA PETERNAK KAMBING TRADISIONAL: PENANDA AWAL ZOONOSIS STRONGYLUS) Insy Nafisah Taufik; Henhen Heryaman; Rini Widyastuti; Mas Rizky A. A. Syamsunarno; Mohammad Ghozali
Jurnal Veteriner Vol 19 No 3 (2018)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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The spread of zoonoses between humans and animals can increase with the presence of specific contacts between the two. As well as intensive contact between farmer and goat. Anemia is a common hematologic change encountered in infection and zoonoses so it can be used as an early indicator for zoonoses. Nevertheless, anemia itself cannot lead to a specific etiology thus differential leukocyte count and goat fecal examination can be a good supporting test. Understanding the etiologies of the disease is critically important in preventing the decline in human’s quality of life as well as economic losses. This cross-sectional study included 30 farmers who were recruited by purposive sampling method. They agreed to do a CBC examination with 22 parameters. From the test, 37% of them showed mild anemia. There were 45% farmers with microcytic hypochromic anemia while the rest had normocytic normochromic anemia. There was an increased number in eosinophil and segmented neutrophil from anemic farmers, 18% and 9% respectively. Besides, 13% of goats physical examination indicated as below normal conditions characterized by lean bodies, lymph node swelling, and pale mucosa. Whereas 38% goat’s fecal test showed evidence of Strongyle eggs. The research suggests a possible interrelation between animals, humans, and the environment with an increased risk of zoonoses. Anemia and eosinophilia that occur can be an early marker which will be decisive not only for the success of the disease progression reduction but also the long term suppression of the economic loss.

AKTIVITAS IMUNOSTIMULATOR EKSTRAK ETANOL BUAH Etlingera rubroloba A.D. POULSEN TERHADAP KADAR CD8 MODEL IN VIVO: IMMUNOSTIMULATORY ACTIVITY OF Etlingera rubroloba A.D. POULSEN FRUIT ETHANOL EXTRACT AGAINST CD8 LEVELS IN VIVO MODEL Muhammad Ilyas Y.; Ajeng Diantini; Mohammad Ghozali; I Sahidin; Wa Ode Nurfinti
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 6 No 2 (2021)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Pendekatan kemotaksonomi genus Etlingera memungkinkan Etlingera rubroloba A.D. Poulsen memiliki kandungan metabolit sekunder sebagai agen imunomodulator. Penelitian ini bertujuan mengetahui efek imunostimulator ekstrak etanol buah E. rubroloba A.D. Poulsen dengan parameter kadar CD8 (Cluster of differentiation) pada tikus jantan galur wistar. Hewan uji tikus sebanyak dua puluh empat ekor dibagi dalam enam kelompok perlakuan yaitu kontrol normal, kontrol pelarut (Na.CMC 0,5%), kontrol positif (ekstrak meniran komersil®), perlakuan ekstrak dosis 200, 300, 400 (mg/kgBB). Perlakuan diberikan selama tujuh hari berturut-turut secara per oral dan pada hari kedelapan masing-masing kelompok diinfeksi bakteri Staphylococcus aureus 0,5 mL secara intraperitonial. Kadar CD8 diukur dengan metode ELISA dan data dianalisis dengan one way ANOVA. Hasil penelitian menunjukan perlakuan dosis ekstrak etanol buah E. rubroloba A.D. Poulsen memiliki efek imunostimulator berdasarkan kadar CD8 yang berbeda signifikan dengan kontrol pelarut (p<0,05), sehingga berpotensi dikembangkan sebagai imunomodulator alamiah.

Hyperferritinemia Correlated with Activated Population of Natural Killer Cells in Pediatric Major β-Thalassemia Patients Adi Imam Cahyadi; Mohammad Ghozali; Reni Ghrahani; Lelani Reniarti; Ramdan Panigoro
Global Medical & Health Communication (GMHC) Vol 9, No 1 (2021)
Publisher : Universitas Islam Bandung

Natural killer (NK) cells act both as cytotoxic and cytokine producers in the innate immune response. Hyperferritinemia resulting from a routine blood transfusion as a specific treatment in major β-thalassemia patients may disturb the cellular immune system’s harmony. This study aims to investigate the correlation between hyperferritinemia and the NK cell subsets in major β-thalassemia settings. Pediatric major β-thalassemia patients who routinely received a blood transfusion at Dr. Hasan Sadikin General Hospital in 2016 were included in this cross-sectional study. Blood samples were treated with the monoclonal antibody of CD3, CD56, and CD16 to count the NK cells subsets as CD56bright, CD56dim, and CD16+ using flowcytometry. CD69+ used as an activation marker. The median fluorescence intensity (MFI) of CD56, CD16, and CD69 was measured. Total iron-binding capacity (TiBC), ferritin, and serum iron level examined as iron status. A Spearman correlation test was used for statistical analysis. Fifty-five blood samples were obtained for analysis. This study reveals that the percentage of CD3− lymphocyte population was correlated with the ferritin levels (r=−0.45, p=0.0009). Positive correlation was revealed between activated population (CD69+) of CD56bright and CD56dim NK cell subsets and hyperferritinemia [(r=0.353, p=0.008) and (r=0.355, p=0.008)]. The activated CD56bright cells was associated with ferritin level (r=0.353, p=0.008) and TiBC (r=0.334, p=0.018). Hyperferritinemia in pediatric major β-thalassemia patients may influence NK cell subsets' balance population, particularly the CD56bright and CD56dim NK cell subsets, then alter their immune response to pathogens. KORELASI ANTARA HIPERFERITINEMIA DAN SEL NATURAL KILLER TERAKTIVASI PADA ANAK DENGAN TALASEMIA BETA MAYORSel-sel natural killer (NK) telah diketahui memiliki peran sitotoksik dan dalam produksi sitokin pada respons imun bawaan. Hiperferitinemia merupakan hasil dari transfusi darah rutin yang dijalani sebagai terapi utama pada talasemia mayor. Penelitian ini bertujuan mempelajari hubungan hiperferitinemia dan sel NK pada talasemia beta mayor. Penelitian potong lintang ini melibatkan anak dengan talasemia beta mayor yang secara rutin menerima transfusi darah di RSUP Dr. Hasan Sadikin selama tahun 2016. Sampel darah diberi marker CD3, CD56, dan CD16 untuk menghitung subset sel NK sebagai CD56bright, CD56dim, dan CD16+ menggunakan flowcytometry. CD69+ digunakan sebagai penanda aktivasi. Median fluorescence intensity (MFI) CD56, CD16, dan CD69 diukur. Kadar TiBC, ferritin, dan Fe serum diperiksa sebagai status besi. Uji korelasi Spearman digunakan pada analisis statistik. Analisis dilakukan terhadap 55 sampel darah anak dengan talasemia. Penelitian ini mendapatkan populasi limfosit CD3 berkorelasi dengan kadar feritin (r=−0,45; p=0,0009). Korelasi positif didapatkan pada populasi teraktivasi (CD69+) dari subset sel CD56bright dan CD56dim NK serta hiperferitinemia [(r=0,353; p=0,008) dan (r=0,355; p=0,008)]. Sel CD56bright teraktivasi berkorelasi dengan kadar feritin (r=0,353; p=0,008) dan TiBC (r=0,334; p=0,018). Hiperferitinemia pada anak dengan talasemia mayor dapat memengaruhi populasi sel NK, khususnya pada subset CD56bright dan CD56dim sehingga berpengaruh pada respons imun terhadap patogen.

Two Serial Hematocrit Level Just After Admission to Predict Dengue Hemorrhagic Fever Severity Fauziyyah Ramadhani; Mohammad Ghozali; Leni Lismayanti
Global Medical & Health Communication (GMHC) Vol 6, No 3 (2018)
Publisher : Universitas Islam Bandung

Dengue hemorrhagic fever (DHF) is still the leading cause of hospitalization and death among children in Indonesia because of plasma leakage leading to shock syndromes. This study aimed to associate the hematocrit difference (first and second) from serial hematocrit (Hct) examination just after admission with DHF severity. A analytical cross-sectional study was involving medical records of pediatric patients with DHF admitted at the pediatric ward and the Pediatric Intensive Care Unit (PICU) of Dr. Hasan Sadikin General Hospital, Bandung in January–December 2015. The subjects excluded if other conditions also cause plasma leakage. The difference in first and second Hct (∆Hct) from serial Hct examination just after admission and DHF grade of severity (DHF I–IV) confirmed by a positive result in serologic tests (anti-dengue IgM/IgG), or detection of dengue virus antigen (NS1Ag test) obtained. Spearman association analysis test used for analysis. A total of 16 subjects with DHF I, 21 subjects with DHF II, 31 subjects with DHF III and two subjects with DHF IV included in this study. There was no significant correlation between positive ∆Hct value (hemoconcentration) and DHF severity (r=0.247, p=0.394, CI=95%). In conclusion, the difference in first and second Hct from serial Hct examination just after admission has no significant association with the disease severity. DUA NILAI HEMATOKRIT SERIAL SESAAT SETELAH ADMISI SEBAGAI PREDIKTOR KEPARAHAN DEMAM BERDARAH DENGUEDemam berdarah dengue (DBD) merupakan penyebab utama hospitalisasi dan kematian anak di Indonesia disebabkan oleh kebocoran plasma yang berujung pada syok. Tujuan penelitian ini mengetahui hubungan perbedaan hematokrit pertama dan kedua pada pemeriksaan hematokrit serial sesaat setelah admisi dengan keparahan DBD. Penelitian merupakan analytical cross-sectional study menggunakan data sekunder berupa rekam medis pasien anak yang dirawat di ruang perawatan anak dan Pediatric Intensive Care Unit (PICU) RSUP Dr. Hasan Sadikin Bandung pada Januari–Desember 2015. Subjek penelitian dieksklusi apabila pada rekam medis terdapat diagnosis lain yang menyebabkan kebocoran plasma. Variabel penelitian ini adalah perbedaan hematokrit pertama dan kedua (∆Hct) pada pemeriksaan hematokrit serial serta diagnosis DBD (DBD I–IV) yang dikonfirmasi oleh hasil positif pada pemeriksaan serologis (IgM/IgG antidengue) atau deteksi antigen virus (NS1Ag). Terdapat 16 subjek DBD I, 21 subjek DBD II, 31 subjek DBD III, dan 2 subjek DBD IV. Dengan menggunakan Uji Analisis Spearman, tidak terdapat korelasi yang signifikan antara nilai positif ∆Hct (hemokonsentrasi) dan tingkat keparahan DBD (r=0,247; p=0,394; CI=95%). Simpulan, perbedaan hematokrit pertama dan kedua pada pemeriksaan hematokrit serial tidak berhubungan dengan keparahan DBD.

Natural resistance-associated macrophage protein 1 gene polymorphisms in thalassemia patients with tuberculosis infection Mohammad Ghozali; Sari Puspa Dewi; Reni Ghrahani; Ani Melani Maskoen; Lelani Reniarti; Edhyana Sahiratmadja; Tri Hanggono Achmad
Paediatrica Indonesiana Vol 56 No 2 (2016): March 2016
Publisher : Indonesian Pediatric Society

that needs regular blood transfusions leading to accumulation of iron in the cells. This iron overload level in macrophage might cause intracellular bacteria, particularly Mycobacterium tuberculosis (MTB) to multiply. Polymorphisms in natural resistance-associated macrophage protein 1 (NRAMP1), a metal transporter across the phagosome membrane, play important role in regulating iron, which is also needed by MTB. Increased iron in thalassemia patients may have an increased potential risk for TB.Objective To compare natural resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms (INT4, D543N, and 3â€™UTR) in thalassemia patients with and without tuberculosis (TB) infection.Methods A cross-sectional measurement of NRAMP1 genetic polymorphisms was performed in pediatric thalassemia patients with TB (n=40) and without TB (n=50). Iron status including serum iron, total iron-binding capacity (TIBC), and ferritin, was compared between the two groups. The NRAMP1 genetic polymorphisms were analysed using polymerase chain reaction/restriction fragment length polymorphism (PCR/RFLP). Allelic and genotypic distributions of each polymorphism were assessed for possible associations with TB infection.Results Mean serum iron and TIBC in thalassemia patients with TB were higher compared to thalassemia patients without TB (mean serum: 166.26 vs. 134.92 Î¼mol/L, respectively; P=0.026) and (mean TIBC: 236.78 vs. 195.84 Î¼mol/L, respectively; P=0.029). In thalassemia patients with TB, we observed significantly higher frequency of the C allele in INT4 (10% vs. 2%, respectively; OR=5.44; 95%CI 1.1 to 26.4; P=0.02) and the TGTG deletion allele (78.8% vs. 51%, respectively; OR=3.56; 95%CI 1.83 to 6.9; P=0.0002) in 3â€™UTR polymorphisms than in thalassemia patients without TB. There were no significantÂ differences in distributions of the A allele between TB and non-TB groups (16.3% vs. 15%, respectively; P=0.84) or the GA genotype (32.5% vs. 30%, respectively; P=0.79) in D543N.Conclusion The NRAMP1 polymorphisms are known to be associated with major gene susceptibility to TB, and in our thalassemia patients this association is even more pronounced.

24-Hour Proteinuria Weakly Correlated with Estimated Glomerular Filtration Rate in Lupus Nephritis Patients Suhendra Praptama; Yulia Hayatul Aini; Mohammad Ghozali; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 8 No. 2 (2016): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Lupus Nephritis (LN) is still the most frequent complication in Systemic Lupus Erythematous (SLE) patients which causing the major and significance morbidity and mortality. Proteinuria and Glomerular Filtration Rate (GFR) serves as objective and routine examinations to assessrenal function. 24-hour proteinuria still regarded as gold standard to quantify amount protein in urine. Estimated GFR (eGFR) is preferably used due its convenient. On the hand, estimated GFR (eGFR) is preferably used due its convenient. However, both of them should be measured in order to determine renal progression and prognosis. Only few studies have been conducted to find out the correlation between 24-hour proteinuria and eGFR in lupus nephritis patients as both of them serve as potential marker in progression of renal involvement. Thisstudy addressed to find out correlation between 24-hour proteinuria and eGFR in lupus nephritis patients.Method: Analytic-correlation study with cross-sectional approach at Dr. Hasan Sadikin Hospital, Bandung was done. Secondary data was used and paralleled with previous study entitled â€œCorrelation of Random Urine Protein Creatinine (P-C) Ratio with 24-Hour Protein Urinein Lupus Nephritis Patientsâ€ carried out from October to December 2014.Correlation coefficient was analyzed by Spearmansâ€™ correlation test.Results: Forty five samples were obtained based on inclusion criteria. Spearmansâ€™ correlation test revealed non significant and very weak correlation between 24-hour proteinuria and eGFR (r=-0.095) with p>0.05.Conclusion: The 24-hour proteinuria and eGFR are weakly correlated. Despite the weakÂ correlation, these examinationsshould be considered as important markers to monitor prognosis of renal involvement in lupus nephritis patients Keywords: Estimated glomerular filtration rate (eGFR),Lupus Nephritis (LN), Proteinuria, Systemic Lupus Erythematosus (SLE).

Overview of Anemia among Systemic Lupus Erythematosus Patients in Reproductive Age Women based on Reticulocyte Hemoglobin Equivalent (RET-He) Level and Reticulocyte Count Ismiana Fatimah Modjaningrat; Amaylia Oehadian; Mohammad Ghozali; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Background: Anemia is a common manifestation found among patients with Systemic Lupus Erythematosus (SLE). It may be caused by iron-deficiency, autoimmune hemolytic, and chronic inflammation. Each anemia has different therapy approachments. Without adequatemanagement, anemia may lead to poor prognosis. By identifying the etiology of anemia, appropriate management could be conducted. Reticulocyte Hemoglobin Equivalent (RET-He) and reticulocyte count test may distinguish anemia based on its etiology. This study aimed to give scientific portrayed of the proportion of anemia based on its etiology among patients with SLE using RET-He and reticulocyte count.Method: This study involved women diagnosed with SLE underwent outpatient treatment in Rheumatology Clinic, Dr. Hasan Sadikin General Hospital during SeptemberOctober 2016. Data were collected from blood exam using 35-parameters hematology Sysmex by calculating levels of hemoglobin, RET-He, and reticulocyte count.Results: Seventy four female patients were volunteered as subject in this study with median of age was 29.5 (16-70) years old. Thirty four (46%) of 74 subjects weresuffering from anemia and 12 (35%) of them were between 25-34 years old. Proportion of iron-deficiency anemia, autoimmune hemolytic anemia, and chronic inflammatory anemia were 14 ( 41%), 13 (38%), and 7 (21%), respectively.Conclusion: Based on hemoglobin, RET-He, and reticulocyte count, iron-deficiency anemia is the most common anemia among patients with SLE in repoductive age.Keyword: Age, Anemia, Reticulocyte, RET-He, Systemic Lupus Erythematosus (SLE)

Co-Authors Adi Imam Cahyadi Adryan Fristiohady Agung W.M. Yodha Amaylia Oehadian Anas Subarnas Andini Sundowo Ani Melani Maskoen Arief Boediono DIANTINI, AJENG - Dwi Wahyudha Wira Edhyana Sahiratmadja Euis Julaeha Fadhal M. Ahmad Fauzia Azzahra Fauziyyah Ramadhani Henhen Heryaman I Sahidin I. Sahidin Insy Nafisah Taufik Ismiana Fatimah Modjaningrat Kikin Winangun Laniyati Hamijoyo Lelani Reniarti Lelani Reniarti Leni Lismayanti Marlinda Siahaan Mas Rizky A. A. Syamsunarno Mas Rizky A.A Syamsunarno Mas Rizky A.A. Syamsunarno Muhammad Ilyas Y Neni Anggraeni Raden Maya Febrianti Ramdan Panigoro Rangga Setiawan Ratu Safitri Reni Ghrahani Reni Ghrahani Riezki Amalia Rini Widyastuti Sahidin Sahidin Sari Puspa Dewi Sofa Fajriah Suhendra Praptama TAKDIR SAILI Tri Hanggono Achmad Tyagita Hartady Uni Gamayani W. Wahyuni Wa Ode Nurfinti Wahyuni Wahyuni Yulia Hayatul Aini Yuni Elsa Hadisaputri

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