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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Kesehatan Folia Medica Indonesiana Jurnal Farmasi Klinik Indonesia Pharmacon MPI (Media Pharmaceutica Indonesiana) Pharmascience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journal of Tropical Pharmacy and Chemistry JFIOnline Pharmaceutical Journal of Indonesia Majalah Farmasetika Jurnal Ilmiah Farmasi Farmasyifa Budapest International Research in Exact Sciences (BirEx Journal) Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Sains dan Kesehatan Journal of Global Pharma Technology

Didik Hasmono

Department Of Pharmacy Practice, Faculty Of Pharmacy, Universitas Airlangga, Surabaya, Indonesia

Author-ID : 278212

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Transportation Other

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STUDI PENGGUNAAN CALCIUM CHANNEL BLOCKER (CCB) PADA PASIEN STROKE HEMORRAGHIC Utami, Nadriatul; Hasmono, Didik; Yusetyani, Lilik
Media Farmasi: Jurnal Ilmu Farmasi Vol 10, No 2: September 2013
Publisher : Universitas Ahmad Dahlan

Stroke adalah penyakit yang dapat menyebabkan kematian di dunia. Di Indonesia, dapat menyebabkan stroke yaitu hipertensi sehingga diperlukan antihipertensi, Metode penelitian yang dilakukan yaitu studi observasi dengan menggunakan sampel menunjukkan penggunaan CCB yaitu nicardipine 64%, nimodipine 12%, amlodipine 2%, dan diltiazem 6%. salah satunya adalah golongan Calcium Channel Blocker (CCB). Maksud penelitian ini yaitu meneliti penggunaan CCB pada pasien dengan hemorrhagicstroke hospitalizations di Rumah Sakit Umum (RSU) Dr. Saiful Anwar Malang.retrospective descriptive method. Analisis dilakukan pada Bulan Januari sampai Desember 2012 pada medical records pasien yang didiagnosa menderita strokehemorrhagic dan menerima pengobatan CCB. Hasil dan Kesimpulan dari 54 jumlah pasien yang menderita stroke mencapai 8,3%. Faktor resiko terbesar yangKata Kunci: Hemorrhagic Stroke, Calcium Channel Blocker (CCB),Hospitalization

PENGGUNAAN OBAT GOLONGAN DIURETIK PADA PASIEN STROKE ISKEMIK DI INSTALASI RAWAT INAP RSU DR. SAIFUL ANWAR MALANG Astutik, Widi; Hasmono, Didik; Syifa’, Nailis
Media Farmasi: Jurnal Ilmu Farmasi Vol 10, No 2: September 2013
Publisher : Universitas Ahmad Dahlan

Stroke iskemik adalah sindrom yang berupa gejala hilangnya fungsi sistem saraf pusat yang berkembang pesat dapat karena atherothrombotis atau emboli, yang keduanya dapat mengganggu aliran darah serebral (CBF). Pemilihan terapi antihipertensi yang sesuai pada pasien stroke sangat berpengaruh dalam keberhasilan terapi yang dilakukan. Diuretik efektif untuk mengurangi tekanan intrakranial. Penelitian ini bertujuan untuk mengetahui pola penggunaan obat diuretik pada pasien stroke iskemik di RSU Dr Saiful Anwar Malang dan meninjau hubungan terapeutik terkait jenis obat, dosis, cara pemberian, interval, frekuensi, dan durasi dengan data klinis dan data laboratorium pasien. Penelitian ini merupakan penelitian observasional dan data dikumpulkan secara retrospektif pada pasien stroke iskemik dari 1 Juli hingga 31 Desember 2012. Profil diuretik tunggal yang digunakan adalah mannitol. Kombinasi diuretik yang ditemukan adalah furosemid dan spironolacton. Penggunaan terapi diuretik pada pasien dengan stroke iskemik sudah sesuai dengan pedoman.Kata kunci: Diuretik, stroke iskemik, rawat inap.

IDENTIFIKASI PROBLEMA OBAT DALAM PHARMACEUTICAL CARE Yulistiani, .; Suharjono, .; Hasmono, Didik; Khotib, Junaidi; Sumarno, .; Rahmadi, Mahardian; Sidharta, Bambang
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 4, No 1 (2008)
Publisher : Indonesian Research Gateway

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Pharmaceutical care is a colaborative process which goal is to prevent, identify, and solve the drug problem. Pharmacists is the one who responsible to pharmaceutical care, to assure the safety and effectiveness of drug use. This works was aimed to identify and analyze drug problems happened during pharmaceutical care. Data was collected from Dr. Syaiful Anwar Hospital Malang, from 1 Januari until 31 August 2006. This was a prospective study (n=138) with descriptive analysis. From the results it can be concluded that drug problems happened during pharmaceutical care in Dr. Syaiful Anwar Hospital Malang consist of: Drug Adverse Reaction (non-elergy side effect 15.22% and toxic effect 3.62%), error in drug choice (untreated indication 18.12%, unappropriate drug to indication 11.59%, unclear drug use 4.35%, unappropriate drug duplication 1.45%), contraindication 0.72%, dosing problem (overtherapy dose 22.46%, overlength therapy 2.90%, subtherapy dose 0.72%), drug interaction (potential interaction 138 cases, manifested interaction 8 cases), and others (patient uncontentment 10.14% and patient unproper care about his/her own disease/therapy 4.35%). ABSTRAKPharmaceutical care merupakan proses kolaboratif yang bertujuan untuk mencegah, mengidentifikasi, dan menyelesaikan problema obat. Dalam pelaksanaan, pharmaceutical care merupakan tanggung jawab profesional farmasis untuk menjamin penggunaan obat yang aman dan efektif dalam meningkatkan kualitas hidup pasien. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisa problema obat yang terjadi dalam pharmaceutical care. Penelitian dilakukan di Rumah Sakit Umum Dr. Syaiful Anwar Malang periode 1 Januari s/d 31 Agustus 2006, merupakan penelitian observasional-data prospektif (n=138) dengan analisis deskriptif. Dari hasil penelitian dapat disimpulkan bahwa macam problema obat yang terjadi meliputi : Reaksi obat yang tidak dikehendaki terdiri dari: efek samping non alergi (15,22%), efek toksik (3,62%); pemilihan obat terdiri dari: obat tidak diresepkan tetapi indikasi jelas (18,12%), obat tidak sesuai indikasi (11,59%), indikasi penggunaan obat tidak jelas (4,35%),duplikasi obat tidak sesuai (1,45%), Kontraindikasi (0,72%); pemberian dosis terdiri dari: dosis terlalu tinggi (22,46%), durasi terapi terlalu panjang (2,90%), dosis terlalu rendah (0,72%); interaksi obat terdiri dari: interaksi potensial 138 kejadian (n=138), manifestasi interaksi (8 kasus); dan problema lain (ketidakpuasan pasien terhadap terapi yang diberikan (10,14%) dan kurangnya perhatian/kesadaran pasien terhadap kondisi/ penyakitnya (4,35%).

Profil Penggunaan Insulin Pada Pasien Diabetes Melitus Tipe 2 Dengan Ulkus/ Gangren Di Rumah Sakit Umum Daerah (RSUD) Kabupaten Sidoarjo Hariyati, Fera; Hasmono, Didik; Kasih, Elisabeth
Jurnal Farmasi Sains dan Terapan Vol 5, No 1 (2018)
Publisher : Jurnal Farmasi Sains dan Terapan

Diabetis mellitus is still a health problem in the world. It is a condition of hyperglycemia which is at risk of causing macrovascular and microvaskular complications. The prevalence of diabetes mellitus continues to increase throughout the world, including in Indonesia. One of diabetes complications is diabetic ulcer or gangrene. Diabetic ulcer or gangrene is common complication of diabetes mellitus wich can be caused by uncontrolled blood glucose levels. The aim of this study was to find the profile of insulin use in patiens with type 2 diabetes mellitus with ulcer or gangren in RSUD Kabupaten Sidoarjo. It was an observational-descriptive study. Data were collected retrospective using purposive sampling method in the period of January 2017 to December 2017 at RSUD Kabupaten Sidoarjo. The results of observational study on 19 patients showed the insulin therapy used in this study, where 42% of patients used single insulin therapy and 58% of patiens used combination insulin therapy. In this study the commonly used single insulin was rapid acting insulin (NovorapidÂ®) 42%, whereas the combination insulin used was rapid acting insulin with long acting insulin (NovorapidÂ®-LantusÂ®) 58%. Based on glycemic target, patients with blood glucose levels reached the glycemic target were 10% of patients, the ones that not reached the glycemic target were 80% of patients and the ones that reached hypoglicemia were 10% of patients. In this study, the severity category of diabetes mellitus patients with ulcers/ gangrene was gangrene 58%, ulcers 26%, cellulitis 11% and sepsis 5%.

Studi Penggunaan Asam Traneksamat pada Penderita Tuberkulosis dengan Hemoptisis di Instalasi Rawat Jalan Rumah Sakit Umum Haji Surabaya Yuni, Santi Eka; Hasmono, Didik; Kasih, Elisabeth; Ayumuyas, Nur Palestin
Jurnal Farmasi Sains dan Terapan Vol 5, No 1 (2018)
Publisher : Jurnal Farmasi Sains dan Terapan

Tuberculosis is one of the world's health problems, especially in developing countries with coughing in the form of blood (hemoptysis) as a sign of this disease. Tranexamic acid can be used as one of the treatments for hemoptysis. Tranexamic acid is a synthesis derivative of aminolenic acid which provides antifibrinolytic effects through reversible blocking of lysine binding sites on plasminogen molecules and inhibits plasmin. This study aims to analyze the pattern of use of tranexamic acid in tuberculosis patients with hemoptysis including dosage, frequency and duration of use in the Outpatient Installation of Surabaya Haji General Hospital. The study was conducted observationally with a retrospective method on medical records of patients diagnosed with tuberculosis with hemoptysis and received treatment for tranexamic acid, then analyzed descriptively. Sampling was done by purposive sampling, from January 1, 2016 to December 31, 2017. From the results of the study, the use of tranexamic acid single dose (3x500mg) as many as 2 patients (67%), 500 mg intravenously as many as 1 patient (33%) and combination with Vitamin K as many as 3 patients. The highest duration of use was 3 days in 11 patients (56%). The use of tranexamic acid in hemoptysis patients related to dose, frequency and duration of use is in accordance with the existing literature.

Pola Penggunaan Antihipertensi pada Pasien Diabetes Mellitus Tipe 2 di Poli Penyakit Dalam RS Bhayangkara Surabaya Pramadani, Yana; Hasmono, Didik; Kasih, Elisabeth; Hartono, Ruddy
Jurnal Farmasi Sains dan Terapan Vol 5, No 2 (2018)
Publisher : Jurnal Farmasi Sains dan Terapan

Diabetes mellitus (DM) is a metabolic disease characterized by symptoms of hyperglycemia. This disease can be caused due to abnormalities in insulin secretion, insulin action or both. Management of diabetes mellitus in general is to improve the quality of life of people with diabetes, namely to eliminate complaints of diabetes mellitus, improve quality of life, and reduce the risk of acute complications; to achieve this goal their blood pressure must be controlled using antihypertensive therapy. The purpose of this study was to examine the pattern of antihypertensive drug use related to the type, dose, and frequency of administration in reducing blood pressure in patients with type 2 diabetes mellitus in the internal medicine clinic of Bhayangkara Hospital Surabaya. The method of this study was observational because researchers did not provide treatment directly to patients. Data were collected retrospectively between August 1 and September 15, 2015. The results showed 80 patients (48%) used single therapy and 86 patients (52%) used combination therapy. The antihypertensive drug that is often used as a single therapy is valsartan (1x80 mg) given orally in 16 patients (20%) and as a combination is valsartan (1x80 mg) + amlodipine (1x10 mg).

Studi Penggunaan Omeprazole pada Pasien Sirosis Hati dengan Hemetamesis Melena Rawat Inap di RSUD Kabupaten Sidoarjo Wiranata, I Made; Hasmono, Didik; Surdijati, Siti
Jurnal Farmasi Sains dan Terapan Vol 4, No 1 (2017)
Publisher : Jurnal Farmasi Sains dan Terapan

Liver cirrhosis is a process of liver cell damage which later becomes fibrosis tissue. Then, the occurrence of liver structural distortion and increased vascularization to the liver resulting in varicose veins or dilation of blood vessels in the gastrointestinal and esophageal areas. Patients with esophageal varices, there is a risk of bleeding from esophageal rupture, the undergone hematemesis (vomiting of blood) and melena (blackish defecate). The therapies used to reduce gastrointestinal bleeding are gastric ulcers drugs such as H2Ras and PPI. The study aimed to determine the pattern of omeprazole use in liver cirrhosis patients with hematemesis melena. The method used was an observational retrospective study in medic record data patients. Sampling was done by consecutive sampling, the period of Juli 1, 2015 until Descember 31, 2015. The results obtained from the study were single use of omeprazole with a dose of 2x40mg/i.v used the most by 22 patients (73.3%). The use of omeprazole with a dose of 2x40mg/i.v combined with other gastric ulcer drugs was 7 patients (23.3%), omeprazole with ranitidin 6 patients, omeprazole with antacid for 1 patient. The use of omeprazole with a dose of 2x40mg was replaced with ranitidin 2x25mg/ml was 1 patient (3.3%). The use of omeprazole given in liver cirrhosis patients with hematemesis melena at the Inpatient Installation of Regional Hospital of Sidoarjo, related dose, route, frequency, interval, and duration of giving was in appropriate with the guidelines contained in the National Formulary.

Studi Penggunaan Sefalosporin Generasi Ketiga pada Pasien Pneumonia di Instalasi Rawat Inap Rumah Sakit Umum Haji Surabaya Worotikan, Natania Imanuella; Hasmono, Didik; Kasih, Elisabeth; Ramdani, Dewi
Jurnal Farmasi Sains dan Terapan Vol 6, No 2 (2019)
Publisher : Jurnal Farmasi Sains dan Terapan

Pneumonia is an acute lung tissue infection caused by inflammation of the lung parenchyma and the presence of exudate compaction in lung tissue. Based on epidemiology, pneumonia can be differentiated into communityacquired pneumonia and health care-associated pneumonia. The HCAP category divided pneumonia into hospital acquired pneumonia and ventilator-associated pneumonia. This study aims to analyze the pattern of third generation cephalosporin use in pneumonia patients based on drug route of administration, dosage, frequency, interval and duration of drug usage, and laboratory data. This study was conducted retrospectively with time limited sampling method during the period of August 1, 2016 - August 31, 2017. The study was conducted in 31 patients with diagnosis of pneumonia undergoing hospitalization and received third generation cephalosporin antibiotic therapy at inpatient installation of RSU Haji Surabaya which traced through Medical Record. All samples were recorded on the data collection sheet, and then the data was recapitulated and analyzed. Based on the observation result, it was found that ceftriaxone with frequency and dose 2x1 g (iv) used as much as 41% (11 people), the combination between ceftriaxone 2x1 g (iv) with levofloxacin 1x1 g (iv) used as much as 22% (4 people). The longest use of third generation cephalosporin antibiotics was ceftriaxone (4-6 days) as much as 35% (12 people).

Profil Terapi Diare Akut pada Pasien Anak Rawat Inap di Rumah Sakit Bhayangkara Surabaya Sandra, Pipit; Hasmono, Didik; Kasih, Elisabeth; Hartono, Ruddy
Jurnal Farmasi Sains dan Terapan Vol 4, No 2 (2017)
Publisher : Jurnal Farmasi Sains dan Terapan

Acute diarrhea in children is defined as defecation more than 3 times per day, with changes in the consistency of feces into fluids with or without mucus and blood lasting either less than a week or up to 14 days, but not more than 14 days in children or infant. Treatment of acute diarrhea can shorten the duration of diarrhea and eradicate the organism which causes the disease. The purpose of this research was to analyze the profile of acute diarrhea treatment in hospitalized pediatric patients at Bhayangkara Hospital Surabaya including the type, dosage, route and the timing of administration which is related to the patientâ€™s medical record data. This research is an observational study in the form of retrospective study in patients with acute diarrhea with a t o t a l sampling technique. The results showed the most commonly used medications for acute diarrhea in children were parenteral rehydration fluid of KDN-1 of (41 patients, 80%) with the most widely used dose (500 cc / 4 hours â†’ 1000 cc / 24 h) IV, t h e pa t t e r n o f single antibiotic use was (43 patients, 84%), the penicillin group, ampicillin, as many as (22 patients, 44%) with the most widely used dose (4 x 250 mg) IV, the most commonly prescribed single antibiotic when discharged from the hospital was cephalosporin group, cefixime, with 17 patients (33%), with the most widely used dose (2 x 20 mg) P.O, sinbiotic with (36 patients, 70%) and the most widely used was dose (1 x 1 sachet) P.O, zinc with (49 patients, 96%) and the most widely used was dose (1 x 1 cth) P.O, vitamin A with (21 patients, 41%), and the most widely used was dose (1 x 500 IU) P.O, antidiarrhea dioctahedral smectite was (43 patients, 84%) and the most commonly used was dose (3 x 1/3 sachets) P.O.

Studi Penggunaan Antiemetik pada Pasien Demam Tifoid Rawat Inap di RSUD Kabupaten Sidoarjo Wardhani, Hety Setya; Surdijati, Siti; Hasmono, Didik
Jurnal Farmasi Sains dan Terapan Vol 4, No 1 (2017)
Publisher : Jurnal Farmasi Sains dan Terapan

Typhoid fever is an infection of the small intestine caused by Salmonella thypi bacteria with symptoms of fever at night. This disease is a contagious disease that can affect many people and is still a health problem, especially in developing countries. This study aims to analyze patterns of antiemetic use in typhoid fever patients. This research was conducted at Sidoarjo District General Hospital using a retrospective method in the period of January 1 to December 31, 2015. The sample was typhoid fever patients who were treated at the Sidoarjo District Hospital. The results obtained using the Health Medical Record (RMK) of patients who have been validated, 161 patients was detected and only 30 patients who is using antiemetic therapy. The antiemetic used is ondansetron. Ondansetron in single dose (3x4mg) iv used in 7 patients (23%) and (3x8mg) iv in 23 patients (77%). The duration of ondansetron use in typhoid fever patients in Sidoarjo District Hospital â‰¤ 2 days was 10 patients and â‰¥ 2 days was 20 patients. Antiemetics used were in accordance with the guidelines and no Drug Related Problems (DRPs) were obtained in typhoid fever patients as seen from their interactions with other drugs, the interval of administration, frequency of administration, duration of treatment, and dose of administration.

Co-Authors Abdulloh Machin Adelia Firandi Adinugraha Amarullah Aghnia Fuadatul Inayah Agriawan Sudirman Agus Sunarko Agus Sunarko Alfa Frista Arta Ana Nurlaili Hidayah Arina Dery Puspitasari Astutik, Widi Ayumuyas, Nur Palestin Ayunda Nur Hidayatiningsih Bambang Sidharta Binti Muzayyanah Budi Suprapti Budiatin, Aniek Setiya Bura, Ursula Dua Klowe Chrysnanda Maryska Claudia Tiffany Dea Ayu Nabilah Dewi Ramdani Dhita Evi Aryani Dini Setiya Praja Dini Setiya Praja, Dini Setiya Diny Puspitasari Donsu, Yosefien Christania Elisabeth Kasih Erwien Isparnadi Ganesha T Trengginas Hariyati, Fera Hartono, Ruddy Hendra Yadi Hidajah Rachmawati Hidayah Karuniawati IGD Ugrasena Irsan Fahmi Almuhtarihan Irsan Fahmi Almuhtarihan Ismawati Jenggo Suwarko Junaidi Khotib K Kuntaman Khairil Armal Kuntaman Kuntaman Landia Setiawan Lilik Yusetyani Mahardian Rahmadi Marcha Debby Saraswati Mareta Rindang Andarsari Maria Angelia Yoshida Maria Lettisia Meo Meiliana, Made Laksmi Mia Melinda Mohammad Saiful Islam Mohammad Subhan Mohammad Subhan Mohammad Subkhan Muhammad Nashrullah Muqoddar Thayyib Nailis Syifa Ni Made Eravikania Putri Darmawan Nun Zairina Nur Hadiyanti Nuraida Wisudani Nurmainah Nurmainah Nurul Ma'rifah Paulus Sugianto Pharmasinta Putri Hapsari Pramadani, Yana Puri Safitri Hanum Ramdani, Dewi Retna Dwi Puspitarini Rino Wahyudi Risa Septinia Rizki Lisya Nugraha Roni Subagyo Ruddy Hartono Ruddy Hartono Ruddy Hartono Ruhaya Fitrina Samirah Samirah Sandra J. Parambang Sandra, Pipit Siti Surdijati, Siti Sofiati Diah Baisuni Suharjono Suharjono Suharjono, Suharjono Sumarno Sumarno Taufiqur Rahman Tista Ayu Fortuna Ulfa Syafli Nosa Umul Fadlilah Usman Hadi Utami, Nadriatul Wanudya Atmajani Wardhani, Hety Setya Widi Astutik Wien Maryati Awdisma Wien Maryati Awdisma Wiranata, I Made Worotikan, Natania Imanuella Yosefien Christania Donsu Yudi Agung Wibisono Yudistira Nurrizky Grahitaning Putra Rohmaana Yulistiani Yulistiani Yulistiani, . Yuni, Santi Eka

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