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The Effect of Casein Addition in Carbonate Apatite Mineral Crystallization Nur Aisyah Nuzulia; Savitri Damayanti; Serin Imsa Arizuni; Yessie Widya Sari
Journal of Medical Physics and Biophysics Vol 6, No 1 (2019)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Milk protein has been considered as one of the influenced factors in bone mineral crystallization. Bone mineral is mainly formed by carbonate apatite in which the crystallization process depends on the two main processes, nucleation and crystal growth. This study showed the formation of carbonate apatite by using precipitation method and observed the influence of casein, milk protein, in carbonate apatite nucleation through synthesis and crystal growth through immersion in SBF.  The result showed that carbonate apatite type B was formed by using precipitation method with chicken eggshells as calcium precursor. The addition of casein concentration could promote the apatite nucleation and crystal growth with low casein concentration ( ≤ 7.5 g.l-1) while high casein concentration addition plays role as an inhibitor.
Composition of Human Bone Mineral by FTIR and Its Relationship to the Age Djarwani S. Soejoko; Yessie Widya Sari; Setia Utami Dewi; Nurizati Nurizati; Kiagus Dahlan; Djaja Surya Atmadja
Journal of Medical Physics and Biophysics Vol 1, No 1 (2014): Inaugural Issue
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Deproteinated human bone with hydrazine indicated that percentage of bone mass mineral increased with individual age in the range of child to adult, and then slowly decreased with ageing. Type of bone and sex also influenced the proportional of mineral in bone. Several information was obtained from infrared spectroscopy measurements. Calcium phosphate in bone mineral was a mixture of amorphous calcium phosphates and apatite crystals that rich of carbonates. Most crystals were carbonate apatite type B, with additional small amount of type A and AB. The splitting factor of υ4 phosphate bands indicated that crystalline degree was regulated by age, increases in the range of child to adult, then decrease up to a certain value (0.16) and finally almost constant. It is predicted that apatite crystals that was formed with less calcium phosphate will accompanied by the insertion of crystallization water in order to maintain the constancy of bone volume.
Injectable Bone Substitute Synthesized from Mangrove Snail Shell Yessie Widya Sari; Reza Pahlevi Rudianto; Nur Aisyah Nuzulia; Sulistioso Giat Sukaryo
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The need for biomaterials tends to increase especially in the field of medicine caused by cases of increasing bone damage. The biomaterial that is being developed for bone implants is hydroxyapatite (HAp). The high value of imports of bone-replacement biomaterials in Indonesia is conidered as a thoughtful problem because of the high price, therefore the development of biomaterials used as a substitute for bone derived from natural materials. In this study, HAp in the form of an injectable bone substitute (IBS) was syntehsized. IBS is a bone-substitute material in the form of a suspension. IBS can be applied by injection to reach deeper areas of bone defects and be able to adjust the shape of bone or tooth defects properly. HAp was synthesized in this study with assistance of microwave irradiation. Mangrove snail shell was used as calcium sources. Furthermore, this study indicated that HAp synthesized from mangrove snail shell had a high potency to be developed as IBS.
The Effect of Variation of Raw Material Ratio on Hydrogel Based on K-Carrageean - Acrylamide as a Carrier of Ammonium Nitrate Fertilizer Hendrawan Laksono; Mersi Kurniati; Yessie Widya Sari; Christina Winarti
Reaktor Volume 21 No. 3 September 2021
Publisher : Dept. of Chemical Engineering, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.328 KB) | DOI: 10.14710/reaktor.21.3.103-108

Abstract

Hydrogels based on natural polymers such as carrageenan are currently being developed to improve efficiency in agriculture. By enriching hydrogels with fertilizers, they will be released slowly into the soil. Enrichment of fertilizers on carrageenan-based hydrogels was carried out and analyzed with the response of swelling ability, gel fraction value of grafting degree, to the hydrogel's ability to release the fertilizer trapped in it. Carrageenan is used because its use as a natural polymer has not been widely explored, especially in the non-food sector. The results showed that the average swelling value of carrageenan-based hydrogel to ammonium nitrate solution ranged from 750.00% - 1,633.33%. The gel fraction values obtained ranged from 74.06% to 87.51%, and the degree of grafting ranged from 85.33% to 93.59%. These values indicate a relatively high degree of tissue density and grafting of acrylamide monomer on carrageenan, which means that the carrageenan:AAm based hydrogel has strong mechanical properties. The ability to release ammonium nitrate samples from the hydrogel carrageenan-based has a value ranging from 8.86% to 44.92% in five days of observation. Interpretation of the test results, the best ratio of carrageenan:AAm is 1:1, due to its relatively low release value but still has good swelling and mechanical properties.Keywords: Hydrogel; Carrageenan; Acrilamyde; Fertilizer release