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All Journal Universa Medicina PALAPA: Jurnal Studi Keislaman dan Ilmu Pendidikan Poltekita : Jurnal Ilmu Kesehatan
IRFAN IDRIS
STMIK AMIKOM Yogyakarta
Religion Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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The Effect Of Compliance Calcium Supplementation modification Tablet On Calcium and Blood Pressure In Pregnant Women Dahniarti, Dhany; Idris, Irfan; Am, Nasrudin
PALAPA: Jurnal Studi Keislaman dan Ilmu Pendidikan Vol 6 No 1 (2018): Mei
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LP2M) STIT Palapa Nusantara Lombok NTB

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (18.214 KB)

Abstract

A low intake of calcium leads to an increase in high blood pressure by stimulating the release of paratiroid and  renin hormones that lead to increase in intracellular calcium concentration in the vasculer smooth muscle cells and result in vasocontriction. This study aims to determine the influence of compliance to supply modified calcium tablet toward calcium level and blood pressure in pregnant mothers. This research was conducted at RSIA Sitti Khadijah I Maternity Hospital Makassar with research design of quasy experiment with pre-post test group control design. There were 30 pregnant mother sampels of prehypertension in gestational age> 20 weeks, 12 pregnant women were given normal calcium tablets and 18 pregnant women given modified calcium tablets for 8 weeks each. Data analysis use paired t test. The results indicate that there is a different changes of calcium level and blood pressure between pregnant mothers of intervention group and control group with the value of p = 0.000 (p<0.05). After intervention averagely the calcium level increase in intervention group 0.4 mg/dl while in control group 0.1 mg/dl, followed by the average decrease in blood pressure of systole and dyastole in the intervention group 15.4/9.6 mmHg while in the control group 3.5/4.5 mmHg.
Body mass index as the most influential factor of high-sensitivity C-reactive protein in non-diabetic adults Mulyamin, Winda; Kurniawan, Liong Boy; Adnan, Endy; Widaningsih, Yuyun; Idris, Irfan; Santoso, Arif; Yustisia, Ika
Universa Medicina Vol. 40 No. 1 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.22-28

Abstract

BACKGROUNDHigh-sensitivity C-reactive protein (hsCRP) has been widely accepted as a predictor of future cardiovascular risk that reflects a microinflammatory state. Obesity linked to microinflammation increases the prevalence of metabolic disorders and cardiovascular diseases. This study aimed to determine the association between several obesity indices namely body mass index (BMI), waist circumference (WC), body fat percentage (fat), and visceral fat (VF) with hsCRP in non-diabetic adults. METHODSThis was a cross-sectional study performed on 80 non-diabetic adults with ages ranging from 20-40 years. The obesity indices BMI, WC, body fat percentage, and VF were measured. We then measured the hsCRP levels using an immunoturbidimetric method. Simple and multiple linear regression tests were used to analyze the association between obesity indices and hsCRP levels. RESULTSMean of log BMI, log WC, and log VF was 1.41 ± 0.08 kg/m2, 1.93 ± 0.06 cm, and 0.95 ± 0.27 units, respectively. Simple linear regression tests showed that log BMI (â=3.506; p<0.001), log WC (â=3.672; p<0.001), log VF (â=0.833; p<0.001), and log systolic blood pressure (â=3.739; p=0.024) had a significant positive correlation with log hsCRP levels. Further multiple linear regression test showed that log BMI (â=3.772; Beta=0.674; p<0.001) had the greater effect on log hsCRP levels compared to other indices. CONCLUSIONS    BMI had a greater influence on hsCRP levels compared to other obesity indices in non-diabetic adults. Body mass index can be used as a better index in predicting hsCRP levels compared to other indices.
Pengaruh Cahaya LED Putih di Malam Hari Terhadap Kadar Malondialdehyde (MDA) Otak dan Histopatologi Sel CA3 dan CA1 Hipokampus Pada Tikus Wistar Jantan Mallisa, Hilda Emma; Arsyad, Aryadi; Idris, Irfan
Poltekita : Jurnal Ilmu Kesehatan Vol. 15 No. 2 (2021): August
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v15i2.452

Abstract

Penelitian ini bertujuan untuk menganalisis pengaruh cahaya LED putih di malam hari terhadap kadar malondialdehyde (MDA) otak dan histopatalogi sel CA3 dan CA1 hipokampus. Jenis penelitian true eksperimental dengan post-test only control group design yang dilakukan pada 24 ekor tikus. Kelompok terbagi berdasarkan waktu paparannya: 15 hari dan 30 hari, masing-masing memiliki kelompok kontrol dan perlakuan. Kelompok kontrol: terang-gelap normal (12L:12D) dan kelompok perlakuan: terang-terang (12L:12L) dengan pencahayaan berasal dari lampu LED putih 1500 lux saat malam hari. Hasil penelitian menunjukkan kadar MDA otak pada kelompok perlakuan lebih tinggi dibandingkan dengan kelompok kontrol dan signifikan (p=0,001). Hasil pemeriksaan histopatologi sel CA3 dan CA1 pada kelompok perlakuan 15 hari didapatkan mengalami kerusakan sedang (50%) hingga berat (50%) sedangkan pada kelompok kontrol 15 hari hanya dominan pada kerusakan ringan (83,3%) dengan hasil yang signifikan (p= 0,011). Pada kelompok perlakuan 30 hari dominan mengalami kerusakan berat (83,3%) sedangkan pada kelompok kontrol 30 hari berada diantara kerusakan ringan (33,3%) hingga sedang (66,7%) dan hasil yang diperoleh signifikan (p=0,012). Cahaya LED putih di malam hari bertindak sebagai stressor apabila intensitas, durasi paparan dan panjang gelombangnya sesuai. Stressor ini meningkatkan produksi ROS dan mengarahkan sel pada stress oksidatif yang ditandai dengan meningkatnya kadar MDA. Peningkatan kadar MDA bersifat neurotoksik pada otak khususnya hipokampus yang mengarahkan sel CA3 dan CA1 pada kerusakan maka perlu adanya pengurangan dalam penggunaan lampu LED pada malam hari
Co-Authors Adnan, Endy Allo, Sarjani Linggi Am, Nasrudin Arif Santoso Arsyad, Muhammad Aryadi Dahniarti, Dhany Hadi, Anto J. Liong Boy Kurniawan, Liong Boy Mallisa, Hilda Emma Mulyamin, Winda Rambulangi, Samrichard Tombeg, Zadrak Widaningsih, Yuyun Yetti R, Erni Yustisia, Ika