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All Journal Indonesian Journal of Pharmaceutical Science and Technology Journal of Pharmaceutical and Health Research Mejuajua Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Jurnal Matematika Dan Ilmu Pengetahuan Alam LLDikti Wilayah 1 (JUMPA) Journal of Pharmaceutical and Sciences.
Yessi Febriani
Fakultas Farmasi, Universitas Tjut Nyak Dhien, Medan, Sumatera Utara, Indonesia.
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Formulation And Antioxcidant Activity Test Of Clay Mask Extracted Ethanol Tamarillo (Solanum betaceum Cav.) Yessi Febriani; Sudewi Sudewi; Rosanna Sembiring
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 3, No. 1 (2021)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.36432

Abstract

Tamarillo (Solanum betaceum Cav.) is a plant that is spread in Java, Bali and North Sumatra, which is rich in nutrients and contain flavonoid as antioxidants that can prevent cell damage due to oxidative stress. Clay-based face masks have a firming and cleansing effect on the skin. Tamarillo was extracted by maceration method using 96% ethanol extract, phytochemical screening was carried out. Clay mask formulation with extract concentration of 1.5%, 2%, 2.5% and blanks. Physical quality test of clay mask preparations included homogeneity test, stability test, pH test, dry time test, irritation test, effectiveness test of clay mask preparation on volunteers using the Skin Analyzer Checkher (Aram), preference test and antioxidant test using the DPPH method. The results showed that the ethanol extract tamarillo contained alkaloids, flavonoids, saponins and could be formulated into a clay mask preparation that was homogeneous, stable, met the pH requirements, and dried time. The results of the effectiveness test using a checkher skin analyzer give the effect of reducing blemishes, reducing pores, moisturizing, not causing irritation to the skin. The antioxidant activity of the ethanol extract tamarillo were in the moderate category with an IC50 value of 201 g/mL and the clay mask preparation of the ethanol extract tamarillo with a concentration of 2.5% was in the medium category with an IC50 value of 221 g/mL.
Formulasi Sediaan Hand Body Lotion Menggunakan Ekstrak Etanol Daging Buah Kedondong (Spondias dulcis Soland. ex Forst. fil.) Sebagai Pelembab Kulit Sudewi Sudewi; Yessi Febriani; Siti Raudah; Ira Nofriani; Nilsya Febrika Zebua
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.861

Abstract

Kedondong fruit (Spondias dulcis Soland. Ex Forst. Fil.) Is a fruit plant originating from South and Southeast Asia and spread in tropical areas. Kedondong fruit contains vitamins A, B and C, carbohydrates, protein and fat. This study aims to determine the pulp of kedondong (Spondias dulcis Soland. Ex Forst. Fil.) In the form of ethanol extract which can be formulated into a hand body lotion which at certain concentrations can provide a moisturizing effect on the skin and is not irritating. This research was conducted using experimental methods, using the test material of the pulp of the kedondong fruit (Spondias dulcis Soland. Ex Forst. Fil.). The ethanol extract of kedondong pulp (Spondias dulcis Soland. Ex Forst. Fil.) Was obtained by maceration using 96% ethanol filter, then concentrated using a rotary evaporator. The preparation is formulated into a hand body lotion with a concentration of 0.5%, 1.5%, 2.5% and 3.5%, as well as a blank. Examination of the physical quality of the preparation includes, homogeneity test, pH test, emulsion type test, stability test, irritation test and effectiveness test of the preparation in moisturizing the skin and comparing with preparations on the market using the Skin Moisturer Checker (AramÒ) and statistical data processing was carried out using the SPSS 26.00 ANOVA method. The results showed that the pulp of kedondong (Spondias dulcis Soland. Ex Forst. Fil.) In the form of ethanol extract can be formulated into a hand body lotion, a homogeneous preparation with the type of oil-in-water emulsion (M / A), has a momentary pH range. After making 6,6-7,3 and pH after 12 weeks of storage 6,3-7,0, the effectiveness test of moisture preparation at a concentration of 3.5% (Formula E) gave moisture (32%) categorized as "moist" which was statistically showed a significant difference with the comparison results, the hand body lotion that was made did not irritate the skin.
Pengenalan dan Pencegahan Diabetes Sejak Dini serta Pengecekan Kadar Gula Darah : Pengenalan dan Pencegahan Diabetes Sejak Dini serta Pengecekan Kadar Gula Darah di Mesjid Al-Karim, Desa Sari Laba Jahe, Kecamatan Sibiru-Biru, Kabupaten Deli Serdang Yessi Febriani; Vriezka Mierza; Pravil Mistriyanto Tambunan; Sumardi; Supran Hidayat Sihotang; Sudewi; Nurmala Sari; Salman; alma Handayani Lubis; Kanne Dachi; Mariani Razali
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 1 No. 2 (2021): Desember 2021
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (514.44 KB) | DOI: 10.52622/mejuajuajabdimas.v1i2.12

Abstract

Menurut angka prevalensi secara global penderita Diabetes mellitus (DM) pada tahun 2017 adalah sebanyak 424,9 juta kasus atau sebesar 8,8% dari keseluruhan penduduk di dunia. Indonesia merupakan negara menempati urutan ke 6 dengan penderita DM sejumlah 10,3 juta. Diabetes mellitus merupakan salah satu penyakit tidak menular yang menyebabkan gangguan metabolisme. Faktor penyebab diabetes mellitus antara lain keturunan, virus yang menimbulkan kerusakan sel beta pankreas, pola makan, kegemukan, pola aktivitas, lingkungan dan kebiasaan tidur. Banyak masyarakat yang belum menyadari penyebab diabetes mellitus adalah dari pola hidup sehari-hari yang salah. Maka perlu di berikan informasi dan edukasi sehingga masyarakat dapat mengenal dan mencegah penyakit diabetes mellitus sejak dini. Sehingga prevalensi terhadap diabetes mellitus akan menurun. Metode penyampaian informasi dan edukasi yang disampaikan yaitu dengan cara persentase. Hasil kegiatan ini meningkatkan pengetahuan masyarakat terhadap penyakit Diabetes mellitus
PELATIHAN PEMBUATAN MASKER PEEL OFF BAGI SISWA/I SMA SINAR HUSNI Eva Sartika Dasopang; Yessi Febriani; Fenny Hasanah; Karolina Sitepu
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 1 No 2 (2022): Juli - Desember 2022
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.76 KB) | DOI: 10.36490/jpmtnd.v1i2.289

Abstract

Kegiatan pelatihan pembuatan masker peel off bagi siswa sinar husni dengan menggunakan bahan dasar PVA dan zat aktif Vitamin c dilakukan oleh time pengabdian kepada masyarakat (PKM) dari Universitas Tjut Nyak Dhien Medan. Kegiatan pelatihan ini bertujuan untuk memberikan wawasan kepada siswa/siswi tentang memberikan ilmu mengenai bagaimana cara membuat sediaan kosmetik dengan vitamin c dan sulfur. Hasil kegiatan menunjukkan bahan penyulihan mengenai formulasi masker peel off dapat memberikan informasi dan pengetahuan bagi siswa-siswi SMA Sinar Husni dan dapat memformulasikan dengan vitamin C dan sulfur
Comparison Of Formulations And Antioxidant Activity Of Transparent Soap From Red And Black Plum (Prunus domestica L.) Yessi Febriani; Vriezka Mierza; Elviza Septimar
Jurnal Matematika Dan Ilmu Pengetahuan Alam LLDikti Wilayah 1 (JUMPA) Vol. 1 No. 2 (2021): September: Mathematics and natural science
Publisher : Lembaga Layanan Pendidikan Tinggi Wilayah I Sumatra Utara (LLDikti I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54076/jumpa.v1i2.45

Abstract

Transparent soap is a type of soap for the face and body to cleanse and protect the skin from free radicals. Plums are fruits that have very high antioxidant capabilities, because they have the content of flavonoids and tannins. This research aims to make transparent soap with the addition of red and black plum juice and compare the antioxidant activity capabilities of soap. This research captures the process of taking cider, phytochemical screening, and soap making. Analysis is pH test, moisture content, foam stability, free alkaline, and antioxidant activity test with DPPH method. The results of the antioxidant activity test are very strong with a value of IC50 < 50 ppm namely red plum juice (30.83 ppm), black plum juice (47.74 ppm), red plum soap (16.52 ppm), black plum soap (12.08 ppm). Soap has a pH of negative blanko (8.5), positive blanko (8.3), red plum (8.6), black plum (8.0). Water content of blanko soap is negative (1.88), blanko positive (2.69), red plum (1.76), black plum (1.83). Negative blanko soap foam stability (50), positive blanko (20), red plum (45), black plum (65), and alkaline free negative blanko soap (0.04), positive blanko (0.08), red plum (0.05), black plum (0.06). Transparent soap meets the quality requirements in accordance with SNI 3532:2016.
Pengaruh fermentasi tepung kulit kopi Oleh Aspergillus oryzae dengan penambahan dua variasi konsentrasi urea dan amonium sulfat terhadap penurunan serat kasar salman salman; Kurniawan Sinaga; Meutia Indriana; Yessi Febriani; Zulfikar Zulfikar
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.475 KB) | DOI: 10.36490/journal-jps.com.v6i1.47

Abstract

The high yield of coffee causes an increase in the amount of coffee husk waste produced, so innovations are needed to process coffee waste so that it can be helpful and not wasted. The study aimed to reduce crude fiber in fermented coffee husks using Aspergillus oryzae to become animal feed. The research was conducted using experimental and descriptive methods: coffee husk flour (Coffea sp.), Aspergillus oryzae, urea, ammonium sulfate, and minerals. Coffee husk flour was fermented in dry media and wet media at room temperature for 24 hours, 48 hours, and 72 hours. After fermentation, test the analysis of the decrease in the amount of crude fiber in the sample using the Wendee method test. The results showed that the fermentation of coffee husk flour (Coffea sp.) using Aspergillus oryzae with the addition of urea, ammonium sulfate, and minerals could reduce the amount of crude fiber. The difference in fermentation media showed that fermentation in wet media gave better crude fiber reduction results than fermentation in dry media. The crude fiber yield of dry media sample N1 is 0.25 grams (25%), and sample N2 is 0.22 grams (22%), while the crude fiber yield of wet media sample N1 is 0.13 grams (13%) and sample N2 is 0.11 grams (11%). Fermentation with Aspergillus oryzae produces ligninase, an enzyme that breaks down lignin which can degrade lignin into simpler compounds.
Formulasi Dan Uji Efektivitas Sediaan Salep Ekstrak Etanol Daun Sintrong (Crassocephalum crepidioides (Benth.) S.Moore) Terhadap Penyembuhan Luka Bakar Pada Marmut Jantan (Cavia porcellus) Muharni Saputri; Yessi Febriani; Olyvia putri Olyvia putri
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.337 KB) | DOI: 10.36490/journal-jps.com.v6i2.52

Abstract

Background; Scar tissue formation due to infectious burns causes delayed maturation of the epidermis. Sintrong contains flavonoids, alkaloids, glycosides, saponins, tannins, and steroids which have anti-inflammatory and antioxidant functions and can protect the body from the harmful effects of free radicals. Preparations with good titration and long exposure times are needed to treat burn problems. This study aims to determine the process of making sintrong leaf ointment (Crassocephalum crepidiodes (Benth.) S.Moore) and the effect of treating burns from sintrong leaf extract in an ointment preparation that has been tested on male guinea pigs (Cavia porcellus). Methods; In this study, test methods were used by means of simplicia preparation, characterization, test phytochemical screening, extraction, formulation and adjustment of ointment preparations to concentrations of 0.5%, 1% and 1.5%, as well as evaluation of ointment tests which included stability tests, sensory tests, homogeneity tests,adhesion, spreadability, pH test, irritation test and efficacy test of ointment preparations. The results obtained from the characteristic examination indicate that the simplicia of the sintrong leaf has fulfilled the requirements of the characteristic test for simplicia. Result; The results of the phytochemical test showed that the positive sintrong leaves contained alkaloids, flavonoids, glycosides, saponins, tannins and triterpenes or steroids. The results of the evaluation of the ethanol extract of sintrong leaf ointment for stable results. The best formulation is formula 3 with a concentration of 1.5% with a wound healing diameter of 0.13 cm on the 21st day
Formulasi sediaan body lotion dari ekstrak etanol buah bit (Beta vulgaris L.) sebagai pelembab kulit dan antioksidan Tri Putri Ananda; Yessi Febriani; Sudewi Sudewi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.51

Abstract

Background; Antioxidants are molecules that can prevent cell damage by free radicals. Beets (Beta vulgaris L.) are known to contain flavonoids which are antioxidants. This study aims to examine the antioxidant activity and skin moisturizing effect without skin irritation in a product formulated as a body lotion from the ethanol extract of beets (Beta vulgaris L.) at a certain concentration. Methods; This research was conducted using an experimental method using beetroot (Beta vulgaris L.) test material obtained by soaking 96% ethanol extract made in body lotion preparations with concentrations of 1.5%, 2%, 2.5% and blank samples. Sample and preparation tests included phytochemical screening, homogeneity test, inoculum pH test, emulsion type test, inoculum stability test, irritation test, water content test and antioxidant activity test. Result; The results showed that beet-based body lotion (Beta vulgaris L.) was a homogeneous preparation with an M/A emulsion and had a pH range immediately after preparation of 6.2 - 6.3 and a pH after cycle test was 6.2 - 6.3. Formula with a concentration of 2.5% (F3) is able to provide moisture in the wet category with a recovery rate of 27.74% lower than similar hand lotions that are applied to wet areas with a recovery rate of 28.18%. The ethanol extract of beets at a concentration of 2.5% (F3) had an IC50 valueof 118.101 µg/mL which indicated a moderate antioxidant class, while the ethanol extract of beets had an IC50 valueof 36.869 µg/mL which was classified as a very strong antioxidant. All body compositions based on ethanol extract of beetroot do not irritate the skin
Sosialisasi Pemakaian Sediaan Obat Salep Mata dan Tetes Mata yang baik pada Masyarakat Siti Muliani Julianty; Eva Sartika Dasopang; Yessi Febriani; Ernawaty Ginting; Syarifah Nadia; Fatia Zahra; Ariyanti Kesuma Wardani
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 2 No 2 (2023): Edisi Juli 2023 - Desember 2023
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v2i2.786

Abstract

Salep mata dan obat mata merupakan salah satu obat steril yang digunakan dalam mengatasi gangguan pada mata. Pemakaian obat mata tanpa menggunakan petunjuk dengan benar dapat menimbulkan bahaya pada mata. Sering terkena polusi udara merupakan salah satu penyebab iritasi pada mata. Masyarakat harus mengetahui tata cara dalam penggunaan dan penyimpanan obat mata. Kurangnya pengetahuan dalam menggunakan dan menyimpan obat mata yang benar dapat memperburuk keadaan mata. Tujuan kegiatan ini adalah menambah wawasan pengatahuan masyarakat terkait cara pemakaian sediaan obat salep mata dan tetes mata yang baik. Kegiatan ini dilakukan dengan cara menjelaskan secara langsung dan pemberian leatfet kepada masyarakat. Sosialisasi cara pemakaian obat sediaan salep mata dan tetes mata memperoleh tanggapan yang baik. Mayoritas masyarakat kurang menyadari cara pemakaian obat yang benar. Hasil dari kegiatan terkait dengan cara pemakaian sediaan obat salep mata dan tetes mata dapat memberikan manfaat yang luas untuk masyarakat dan mendapatkan dampak positif yang maksimal dengan cara penggunaan sediaan yang benar.
Co-Authors alma Handayani Lubis Ariyanti Kesuma Wardani Elviza Septimar Ernawaty Ginting Eva Sartika Dasopang Fatia Zahra Fenny Hasanah Ira Nofriani Kanne Dachi Karolina Sitepu Kurniawan Sinaga Mariani Razali Meutia Indriana Muharni Saputri Nilsya Febrika Zebua, Nilsya Febrika Nurisma Kemalasari Nurmala Sari Olyvia putri Olyvia putri Pravil Mistriyanto Tambunan Rosanna Sembiring Salman salman salman siti muliani julianty Siti Raudah Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sumardi Supran Hidayat Sihotang Syarifah Nadia Tri Putri Ananda Vriezka Mierza Zulfikar Zulfikar