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All Journal Jurnal Pendidikan dan Pembelajaran Berkala Kedokteran ANALITIKA JURNAL DIVERSITA Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences JPI (Jurnal Pendidikan Inklusi)
Istiana Istiana
Universitas Medan Area
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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UJI EFEKTIVITAS BEBERAPA LARVASIDA TERHADAP LARVA NYAMUK Aedes aegypti DARI BANJARMASIN BARAT Istiana, Istiana
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.185

Abstract

Dengue Haemorrhagic Fever (DHF) is a dangerous infectious disease caused by the dengue virus and is transmitted through the bite of the mosquito Aedes aegypti. DHF control depends on controlling mosquitoes and larvae. Currently larvicidal control still uses temefos, although some studies have reported the presence of resistance. Larvicides that WHO recommended as a substitute temefos is permethrin. In addition there are some new larvicides derived from the class of insect growth regulator (IGR) which contain active pyriproksifen and active ingredients methopren. This study aims to determine the effectiveness of larvicides and effective concentration to kill 50% of larvae of Aedes aegypti from the sub Banjarmasin West. This study is an experimental study design with Posttest-Only Control Group Design with permethrin dose group was 0.0015 g / l; 0.0018 g / l; 0.002 g / l; 0.0022 g / l; 0.0025 g / l; and 0.0030 g / l, for pryriproksifen use dose groups of 0.5 ppm, 0.1 ppm, 0.05 ppm, 0.01 ppm, 0.008 ppm, 0.005 ppm, and methopren with dosis0 group g / l, 0, 0063 g / l, 0.0025 g / l, 0.005 g / l, 0.01 g / l, and 0.1 g / l. Each treatment group was exposed to larvae of Aedes aegypti larvae and change shape as well as the deaths were followed for 10 days. The results showed that the effective dose of permethrin kills 50% of larvae (Lethal Concentration / LC50) 24 hours ranged from 24 hour LC50 0.01439 - 0.01829 mg / l, with an average of 0.01671 mg / l and 24-hour LC99 ranged from 0.02856 - 0.03852 mg / l with an average of 0.03196 mg / l. This study showed that the larvae of Aedes aegypti in the district of West Banjarmasin are resistant to permethrin. As for pyriproksifen larvicides effectively killed larvae by 70% after seven days of exposure, and for larvicidal with active methopren killed 50% of larvae on the eighth day. This study shows that larviciding of IGR group can be an alternative in the area that has been declared resistant to abate as in the sub-district of West Banjarmasin. Keywords: effectiveness, permethrin, pyriproksifen, methopren, Aedes aegypti
Perbandingan Efektifitas Rapid Diagnostic Test (Rdt) Dengan Pemeriksaan Mikroskop Pada Penderita Malaria Klinis : Di Kecamatan Jaro Rakhman, M. Aulia; Istiana, Istiana; Al Audhah, Nelly
Jurnal Berkala Kedokteran Vol 9, No 1 (2013): April 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i1.916

Abstract

ABSTRACT: Malaria is a disease caused by genus Plasmodium. Enforcement of the diagnosis malaria is microscopic examination of thick blood droplets and thin blood droplets and examination of Rapid Diagnostic Test (RDT). Gold standard for the diagnosis of malaria is microscopic examination. Rapid Diagnosis Test (RDT) is one alternative diagnostic tool in detecting Plasmodium quickly and doesn’t require special skill. The purpose of this study was to discover the effectiveness of Rapid Diagnostic Test (RDT) compared with microscopic examination in patient with clinical malaria in Jaro Sub-district. This study was a descriptive analytic study using the data of the result of malaria examination means of microscope examination and RDT on January – June 2012, with cross sectional approach. RDT examination result showed 98% sensitivity value, 100% specificity value, 100% positive predictive value and 98% negative predictive value compared with microscopic examination. Statistical test using Mc.Nemar test with 95% level of confidence interval p=0,125 (p>0,05). This show was no difference in the effectiveness of RDT examination and microscopic examination of patients with clinical malaria in Jaro Sub-district.Keywords: effectiveness, Rapid Diagnostic Test (RDT), microscopic examinationABSTRAK: Malaria adalah penyakit yang disebabkan oleh genus Plasmodium. Penegakkan diagnosis malaria adalah dengan pemeriksaan mikroskopis berupa tetesan darah tebal dan tetesan darah tipis serta pemeriksaan Rapid Diagnostik Test (RDT).  Gold standard untuk diagnosis malaria adalah dengan pemeriksaan mikroskopis. Rapid Diagnosis Test (RDT) merupakan salah satu alat diagnostik alternatif dalam mendeteksi Plasmodium secara cepat dan tidak memerlukan keterampilan khusus. Tujuan penelitian ini untuk mengetahui efektifitas Rapid Diagnostic Test (RDT) dibandingkan dengan pemeriksaan mikroskop pada penderita malaria klinis di Kecamatan Jaro. Penelitian ini merupakan penelitian deskriptif analitik menggunakan data hasil pemeriksaan malaria melalui pemeriksaan mikroskop dan RDT selama bulan Januari – Juni 2012 dengan pendekatan cross sectional. Hasil penelitian menunjukkan pemeriksaan RDT memiliki nilai sensitivitas 98%, spesifisitas 100%, nilai duga positif 100% dan nilai duga negatif 98% dibandingkan dengan pemeriksaan mikroskopis. Analisis uji statistik menggunakan uji Mc.Nemar dengan tingkat kepercayaan 95% didapatkan nilai p=0,125 (p>0,05)S. Hal ini menunjukkan tidak terdapat perbedaan efektifitas  pemeriksaan RDT dan mikroskopik pada penderita malaria klinis di Kecamatan Jaro.. Kata-kata kunci: efektifitas, Rapid Diagnostic Test (RDT), pemeriksaan  mikoskopisABSTRACT: Malaria is a disease caused by genus Plasmodium. Enforcement of the diagnosis malaria is microscopic examination of thick blood droplets and thin blood droplets and examination of Rapid Diagnostic Test (RDT). Gold standard for the diagnosis of malaria is microscopic examination. Rapid Diagnosis Test (RDT) is one alternative diagnostic tool in detecting Plasmodium quickly and doesn’t require special skill. The purpose of this study was to discover the effectiveness of Rapid Diagnostic Test (RDT) compared with microscopic examination in patient with clinical malaria in Jaro Sub-district. This study was a descriptive analytic stud
Hubungan Riwayat Malaria Sebelumnya dengan Kejadian Malaria Berdasarkan Hapusan Darah Pendonor di PT Pama Kecamatan Kintap Putera, Wahyu Aditia Husada; Al Audhah, Nelly; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.930

Abstract

ABSTRACT: Malaria is a disease that is caused by the Plasmodium genus and still become a problem around the world due to high mortality and morbidity. Several types of Plasmodium sp can be transmitted through blood transfusion. The aim of this study was to determine the relationship between history of previous malaria exposure with the event of malaria through donor’s blood smear at PT Pama Kintap subdistrict, Tanah Laut district. It was a survey of analytic-deskriptive study that performed on blood donors by using a questionnaire to see a history of previous malaria, and a smear of blood transfusion donors to see the Plasmodium sp in the blood transfusion. Sample of the research used total sampling method and gained 46 samples. The result was 4 (8.7%) had a previous history of malaria, and 2 (4.3%) was found some Plasmodium sp from their transfusion blood smear. Statistical analyisis used Fischer test, showed p value = 0.006 (p <0.05) which means there is a significant relation between a history of previous malaria exposure with the event of malaria through donor’s blood smear at malaria’s endemic region. Keywords: history of malaria, incident of malaria, blood donor ABSTRAK: Malaria adalah penyakit yang disebabkan oleh Plasmodium dan masih menjadi masalah di seluruh dunia karena angka morbiditas dan mortalitas yang tinggi. Beberapa jenis Plasmodium sp dapat ditularkan melalui transfusi darah. Penelitian ini bertujuan untuk mengetahui hubungan riwayat penyakit malaria sebelumnya dengan kejadian malaria berdasarkan hapusan darah pendonor di PT Pama kecamatan Kintap di kabupaten Tanah Laut. Penelitian ini bersifat survey analitic-descriptive yang dilakukan pada pendonor darah dengan menggunakan kuesioner untuk melihat riwayat malaria sebelumnya, dan hapusan darah transfusi pendonor untuk melihat adanya Plasmodium sp. Sampel penelitian menggunakan teknik total sampel dan mendapatkan 46 pendonor. Hasil penelitian menunjukkan bahwa 4 orang (8,7%) memiliki riwayat malaria sebelumnya, dan 2 orang (4,3%) ditemukan plasmodium dalam hapusan darah transfusinya. Analisis statistik menggunakan uji Fischer mendapatkan p value = 0,006 ( p < 0,05) yang menunjukkan ada hubungan yang bermakna antara riwayat malaria sebelumnya dengan kejadian malaria melalui hapusan darah transfusi pendonor. Kata-kata kunci: riwayat malaria, kejadian malaria, donor darah
Studi Interaksi Farmakodinamik Efek Analgesik Kombinasi Perasan Buah Mengkudu (Morinda citrifolia) dengan Parasetamol: Kajian terhadap waktu reaksi nyeri menggunakan metode hot plate pada mencit (Mus musculus) Wirasari, Firda; Bakhriansyah, Mohammad; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.927

Abstract

ABSTRACT: Mengkudu (Morinda citrifolia) has been proven in  possessing the analgesic effect. The similarity of analgesic activity of mengkudu and paracetamol enable the existence of analgesic effect interaction synergistically when they are both combined. The objective of this research is to find out the pharmacodynamic interaction between the juice of mengkudu and paracetamol. The research was an experimental research with posttest-only with control group design. The control group consists of 6 groups, and each group had 5 mice. The 1st group was given aquadest 0.5 ml; the 2nd group was given the juice of mengkudu 0.042 mg/g BB; the 3rd group was given paracetamol 0.065 mg/g BB; while the 4th , 5th, 6th groups were given the combination of mengkudu juice 0.042 mg/g BB and paracetamol with the dosages 0.01625 mg/g BB; 0.0325 mg/g BB; 0.065 mg/g BB, respectively. Treatments were given 10 minutes before mice were painly induced by using hot plate. The average of onset of pain for group I, II, III, IV, V, VI were 5.36; 8.28; 8.02; 9.67; 10.5 and 11.74 seconds, respectively. Statistical anaysis using Kruskal Wallis showed that there was significance difference among groups (p = 0.000) while the very potential effect was in group with paracetamol dosage on 0,065 mg/g BB. Based on this research, it can be concluded that there is sinergycal interaction between the combination of mengkudu juice with paracetamol on mice. Keywords : analgesic effect, mengkudu, paracetamol, onset of pain, synergycal interaction ABSTRAK: Mengkudu (Morinda citrifolia) telah terbukti memiliki efek analgesik. Kesamaan aktivitas analgesik buah mengkudu dan parasetamol memungkinkan adanya interaksi efek analgesik yang sinergis ketika keduanya dikombinasikan. Tujuan penelitian ini adalah untuk mengetahui interaksi farmakodinamik efek analgesik kombinasi perasan buah mengkudu dengan parasetamol. Penelitian ini bersifat eksperimental dengan pendekatan posttest-only with control group design, terdiri dari 6 kelompok. Setiap kelompok memiliki 5 ekor mencit. Kelompok I diberikan aquadest 0,5ml, kelompok II diberikan perasan buah mengkudu dengan dosis 0,042 mg/g BB, kelompok III diberikan parasetamol 0,065 mg/g BB sedangkan, kelompok IV, V, VI diberikan kombinasi perasan buah mengkudu 0,042 mg/g BB dan parasetamol dengan dosis masing-masing: 0,01625 mg/g BB; 0,0325 mg/g BB; 0,065 mg/g BB, diberikan 10 menit sebelum dilakukan induksi nyeri di atas hot plate. Rerata waktu reaksi nyeri mencit pada kelompok  I, II, III, IV, V, dan VI berturut-turut adalah 5,36; 8,28; 8,02; 9,67; 10,5 dan 11,74 detik. Hasil analisis statistik Kruskal-Wallis menunjukkan bahwa terdapat perbedaan yang bermakna antara berbagai kelompok dengan nilai p = 0,000, dengan dosis kelompok kombinasi yang paling potensial memberikan efek analgesik adalah kelompok dengan dosis parasetamol 0,065 mg/g BB. Berdasarkan penelitian ini dapat disimpulkan bahwa terdapat interaksi yang sinergis pada kombinasi perasan buah mengkudu dengan parasetamol pada mencit. Kata-kata kunci: efek analgesik, buah mengkudu, parasetamol, waktu reaksi, interaksi.
NILAI DIAGNOSTIK SKOR KLINIS DIBANDINGKAN DENGAN BIOPSI PATOLOGI ANATOMI DALAM MENDIAGNOSIS PASIEN KARSINOMA NASOFARING Rahmayanti, Dini Desviana; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.188

Abstract

Nasopharyngeal malignancy is the most commonly found among head and neck malignancies. Generally, nasopharyngeal cancer, has a good prognosis if it is detected as soon as possible. It is very important to diagnose it earlier because survival rate can be longer if therapy is given early. This study aims to determine the diagnostic value of clinical scores compared with histopathology biopsy to diagnose nasopharyngeal carcinoma in patients of RSUD Ulin Banjarmasin in the period 2012-2014. Subjects of this study were patients of RSUD Ulin Banjarmasin Hospital which is suspected nasopharyngeal carcinoma, who have examined the clinical symptoms by history and physical examination, had been registered in the medical record, and had been examined with histopathology biopsy. Data of clinical examination and histopathology biopsy from each sampel were collected for clinical symptom scores were analyzed according to get sensitivity value, specifity value, positif predictive value, and negative predictive value.Total subject of this research was 30. In this study, a minimum clinical score to lead to a nasopharyngeal malignancy that if found clinical score of 4, with a sensitivity, specifity, positive predictive value , and negative predictive value of 75%, 83.33%, 94.74%, 45.45% respectively. Clinical characteristics have high sensitivity and specifity to diagnose nasopharyngeal carcinoma. Keywords: diagnostic value, clinical scores, nasopharyngeal carcinoma
Efektifitas Pyriproxyfen terhadap Larva Aedes aegypti yang Diambil dari Wilayah Banjarmasin Timur Akbar, Ali; Istiana, Istiana; Al Audhah, Nelly
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.928

Abstract

ABSTRACT: Dengue Haemorraghic Fever disease (DHF) is dangerous contagious disease which is caused by dengue virus which is brought by Aedes aegypti mosquito. Controling DHF depends on the control of the mosquito and its larvae. One of alternative larvacide that can control Aedes aegypti larvae is larvacide with active ingredient pyriproxyfen as Insecth Growth Regulator (IGR) which does not influece the hygiene of water, safety and does not increase the resistancy. The purpose of the study is to study and calculate efficacy of an IGR pyriproxyfen against Aedes aegypti larvae which was only collected from East Banjarmasin. The research is an experimental research that used seven kind dozes of IGR: follows 0,1 ppm, 0,05 ppm, 0,01 ppm, 0,008 ppm, 0,005 ppm, 0,003 ppm, and control. Each doze used four replications. The research results showed that IGR was effective to kill more than 70% larvae after seven days. The results of probit analysis were 0,001 ppm ana 0,065 ppm to kill 50% and 90% larvae. Keywords: Dengue Haemorraghic Fever, pyriproxyfen, Aedes aegypti ABSTRAK: Penyakit Demam Berdarah Dengue (DBD) adalah penyakit menular berbahaya yang disebabkan oleh virus dengue yang dibawa oleh nyamuk Aedes aegypti. Pengendalian DBD bergantung pada pengendalian nyamuk dan larvanya. Salah satu larvasida alternatif yang dapat digunakan untuk mengendalikan larva nyamuk Aedes aegypti adalah larvasida yang berbahan aktif pyriproxyfen dan berasal dari golongan Insect Growth Regulator (IGR) yang tidak mempengaruhi kebersihan air, aman, dan tidak meningkatkan resistensi. Penelitian ini bertujuan untuk mengetahui dan menghitung efikasi IGR berbahan aktif pyriproxyfen terhadap larva Aedes aegypti yang berasal dari Kecamatan Banjarmasin Timur. Penelitian ini merupakan penelitian eksperimental yang menggunakan tujuh macam dosis 0,1 ppm, 0,05 ppm, 0,01 ppm, 0,008 ppm, 0,005 ppm, 0,003 ppm, dan kontrol. Setiap dosis menggunakan empat kali pengulangan. Hasil penelitian menunjukan bahwa IGR efektif untuk membunuh 70% larva uji setelah tujuh hari pemaparan. Berdasarkan analisis probit dosis yang diperlukan untuk membunuh 50% (LC50) dan 90%(LC90) larva uji adalah berturut-turut sebesar 0,001 ppm dan 0,065 ppm. Kata kunci : Demam Berdarah Dengue,  pyriproxyfen, Aedes aegypti
HUBUNGAN REAKSI LIMFOSIT DENGAN DERAJAT KEGANASAN KANKER SERVIKS DI RSUD ULIN BANJARMASIN PERIODE JANUARI-DESEMBER 2013 Hanafi, Ahmad Marzuki Rifki; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.184

Abstract

Cervix cancer is a malignancy in women at most 3rd in the world, which occurs in the cervix uteri. Etiologic factor of cervix cancer is infection with human papilloma virus (HPV). Lymphocyte very important role in eradicating cancer cells. However, cervix cancer mortality rates remain high, especially in poor differentiated grade. This may be related to the level of mixed lymphocyte reaction and depending on the status of the tumor grade. This study aimed to determine the correlation between lymphocyte reaction with tumor grade in patients with cervix cancer in RSUD Ulin Banjarmasin period from January to December 2013. The study design was observational analytic study with cross-sectional approach. The data were taken in the form of primary data in the form of checks degrees lymphocytes with a microscope. The population is all women who underwent histopathological examination in RSUD Ulin period from January to December 2013. The sample was taken by purposive sampling as many as 56 people who had met the inclusion criteria. The results showed that the incidence of cervix cancer well-differentiated at most that 25 cases (44%) and lymphocyte reaction that many are mild lymphocyte reaction as much as 33 cases (59%). Somersd test analysis in the study obtained value (aprox sig. = 0.761). These results indicate that there is no significant correlation between lymphocyte reaction with tumor grade cervix cancer in RSUD Ulin period from January to December 2013. Keywords: cervix cancer, tumor grade, lymphocyte reaction
HUBUNGAN ANTARA KEPEMIMPINAN WANITA DENGAN DISIPLIN KERJA Wulan, Retno; Istiana, Istiana
ANALITIKA Vol 6, No 1 (2014): ANALITIKA JUNI
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.718 KB)

Abstract

Penelitian ini bertujuan untuk mengetahui hubungan antara kepemimpinan wanita dengan disiplinkerja.Penelitian ini menggunakan metode kuantitatif dengan prosedur survey. Populasi penelitian adalah seluruh karyawan PT. PLN (Persero) Area ‘X’ yang berjumlah 30 orang yang dipimpinolehseorangwanita.Pengambilansampelmenggunakantekniktotal samplingyang berarti adalahseluruhkaryawan PT. PLN Persero Area ‘X’ sejumlah 30 orang berpartisipasi sebagai subyek penelitian. Data penelitian dikumpulkan dengan menggunakan skala psikologis, yaitu skala persepsi terhadap kepemimpinan wanita dan skala disiplin kerja yang dikembangkan oleh peneliti berdasarkan teori yang relevan. Data yang terkumpul dianalisa dengan menggunakan uji Pearson product moment. Hasil analisa data menunjukkan adanya hubungan positifyang signifikan antara persepsi terhadap kepemimpinan wanita dengan disiplinkerja. Hasil lainnya menunjukkan bahwa subyek penelitan  memiliki persepsi yang negatif terhadap kepemimpinan wanita dan memiliki tingkat kedisiplinan kerja yang tergolong sedang.
PERBEDAAN KEJADIAN DISFUNGSI SEKSUAL PADA WANITA DENGAN DIABETES MELITUS DAN TANPA DIABETES MELITUS Amelia, Helna; Khatimah, Husnul; Istiana, Istiana
Berkala Kedokteran Vol 12, No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i2.1861

Abstract

Abstract: Sexual dysfunction in woman with diabetes mellitus has received less attention from the doctors. The study about sexual dysfunction in female is relatively less than sexual dysfunction in male. The aim of this study was to analyze the difference of sexual dysfunction in diabetes and non-diabetes female at Ulin and Dr. H. Moch. Ansari Saleh Hospitals Banjarmasin. This study was an observational analytic study with case control approach. Diabetes and non-diabetes female that came to the subspecialist polyclinic in Ulin hospital and to the internal medicine polyclinic in Dr. H. Moch. Ansari Saleh hospital period July-September 2015 that meet to the inclusion criteria were included as sample of this study. Female sexual dysfunction was assessed using the Female Sexual Function Index (FSFI) questionnaire. From 30 diabetes females, there were 19 females (63,3%) had sexual dysfunction and from 30 non-diabetes females there were 14 females (46,7%) had sexual dysfunction. The data analysis using chi-square was resulted p=0,299 that means there was no significant difference. It was concluded that there was no significant difference of sexual dysfunction in diabetes and non-diabetes female. Keywords:sexual dysfunction, female, diabetes mellitus Abstrak: Disfungsi seksual pada wanita dengan diabetes melitus (DM) belum banyak mendapat perhatian dari dokter. Penelitian tentang disfungsi seksual pada wanita juga relatif sedikit jika dibandingkan dengan disfungsi seksual pada laki-laki. Penelitian ini bertujuan untuk menganalisis perbedaan kejadian disfungsi seksual pada wanita dengan DM dan tanpa DM di RSUD Ulin dan RSUD Dr. H. Moch. Ansari Saleh Banjarmasin. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan case control.Pasien wanita DM dan tanpa DM yang datang ke poliklinik subspesialis RSUD Ulin dan poliklinik penyakit dalam RSUD Dr. H. Moch. Ansari Saleh Banjarmasin periode Juli-September 2015 yang memenuhi kriteria inklusi menjadi sampel pada penelitian ini. Disfungsi seksual wanita dinilai dengan menggunakan kuesioner the Female Sexual Function Index (FSFI). Dari 30 wanita DM yang menjadi subjek penelitian, terdapat 19 orang (63,3%) yang mengalami disfungsi seksual dan dari 30 wanita tanpa DM yang menjadi subjek penelitian, terdapat 14 orang (46,7%) mengalami disfungsi seksual. Analisis data dengan menggunakan uji chi-square didapatkan nilai p=0,299 yang berarti tidak terdapat perbedaan yang bermakna.  Berdasarkan penelitian yang dilakukan dapat diambil kesimpulan bahwa tidak terdapat perbedaan yang bermakna antara kejadian disfungsi seksual pada wanita DM dan tanpa DM. Kata-kata kunci: lingkar pinggang, obesitas sentral, diabetes melitus, disfungsi ereksi
EFEK KOMBINASI PARASETAMOL DAN KODEIN SEBAGAI ANALGESIA PREEMPTIF PADA PASIEN DENGAN ORIF EKSTREMITAS BAWAH Sahurrahmanisa, Sahurrahmanisa; Sikumbang, Kenanga Marwan; Istiana, Istiana
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v13i1.3445

Abstract

Abstract: Postoperative pain is a complex pain response which often occurred in post-operative patient. Effective pain management is conducted by giving preemptive analgesia, preventive analgesia and multimodal. The purpose of this study was to analyze the effect combination of paracetamol 325 mg and codeine 10 mg in a patient with ORIF inferior extremity. This was an observational analytic study with a cross sectional method and 32 respondents were included by consecutive sampling method. The result of this study, in group with the combination of paracetamol and codeine there are 4 respondents (25.0%) of mild pain, 12 respondents (75.0%) of moderate pain, and there’s none had severe pain, and the group without combination therapy there’s no mild pain, 7 respondents (43.8%) of moderate pain, and 9 respondents (56.2%) of severe pain. The statistic analyses with Kolmogorov Smirnov p-value <0.05, it can be concluded that in this study a combination of paracetamol and codeine are effective as a preemptive analgesia. Keywords: postoperative pain, preemptive analgesia, visual analog scale (VAS), paracetamol, codeine Abstrak: Nyeri pasca bedah merupakan respon nyeri yang sering dirasakan pasien setelah pembedahan dengan respon yang kompleks. Penanganan nyeri yang efektif dilakukan dengan pemberian analgesia preemptif, analgesia preventif, dan analgesia multimodal. Tujuan penelitian ini untuk menganalisi efek kombinasi parasetamol 325 mg dan kodein 10 mg sebagai analgesia preemptif pada pasien dengan ORIF ekstremitas bawah. Penelitian ini menggunakan rancangan observasional analitik cross sectional dengan teknik consecutive sampling didapatkan 32 sampel. Hasil penelitian, pada kelompok yang diberikan kombinasi parasetamol dan kodein sebanyak 4(25.0%) nyeri ringan, 12 (75.0%) nyeri sedang dan tidak didapatkan nyeri berat, sedangkan pada kelompok yang tidak diberikan kombinasi parasetamol dan kodein tidak ditemukan nyeri ringan, sebanyak 7 (43.8%) nyeri sedang dan 9 (56.2%) nyeri berat. Analisa statistik menggunakan Komogorov Smirnov didapatkan perbedaan yang signifikan antara kedua kelompok dengan nilai p value < 0,05 sehingga dapat disimpulkan pada penelitian ini kombinasi parasetamol dan kodein dapat digunakan sebagai analgesia preemptif. Kata-kata kunci: nyeri paska bedah, analgesia preemptif, visual analog scale (VAS) , parasetamol, kodein.
Co-Authors Ahmad Husairi Ahmad Marzuki Rifki Hanafi, Ahmad Marzuki Rifki Ainnayyah, Refiana Ali Akbar Alim, Linawati Amelia, Helna Asri, Jannah Safira Azizaturridha, Aulia Barra Gerry Prakoso, Barra Gerry Dini Desviana Rahmayanti, Dini Desviana Farida Heriyani Firda Wirasari, Firda Henny Sanulita Herviani, Vivi Kurnia Husnul Khatimah Ika Kustiyah Oktaviyanti Kenanga Marwan Sikumbang, Kenanga Marwan Lesiana, Rina Lisda Hayatie, Lisda M. Aulia Rakhman, M. Aulia Maulida, Rohma Isni Mohammad Bakhriansyah Muhammad Sahal Imaduddin, Muhammad Sahal Muthmainah, Noor Nadila, Isfarani Nelly Al Audhah Ningtyas, Amelia Astian Nurrachaman, Nurrachaman Patriantoro, Patriantoro Rabidhamadi, Herry Syawali Ramadhan, Lingga Fajar Retno Wulan Sahurrahmanisa, Sahurrahmanisa Santana, Indah P Sasongko, Tri Budi Sumarjan Sumarjan, Sumarjan Susianto, Oky Ulfadila, Lulu Hasna Wahyu Aditia Husada Putera, Wahyu Aditia Husada Wahyuni, Nini Sri Wydiamala, Erida