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Faktor-Faktor Risiko Yang Berhubungan Dengan Kejadian Kanker Prostat di Poliklinik Bedah Urologi RSUP H. Adam Malik Medan Yolanda Eliza Putri Lubis
PRIMER (Prima Medical Journal) Vol. 3 No. 2 (2018): Edisi Oktober
Publisher : Universitas Prima Indonesia

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Abstract

Latar Belakang: Penyakit kanker merupakan salah satu penyebab kematian utama di seluruh dunia. Seiring dengan perjalanan usia, khususnya bagi pria usia lanjut harus meningkatkan kewaspadaan pada kondisi kesehatan tubuhnya. Kanker prostat umumnya terjadi pada pria di usia 50 tahun ke atas, tetapi sekarang ada juga yang berusia dibawah 50 tahun terkena kanker prostat, hal ini disebabkan oleh gaya hidup pria yang kebanyakan sudah merokok dan minum alkohol dari usia sangat muda. Faktor-faktor risiko kanker prostat cukup bervariasi, meliputi riwayat keluarga, obesitas, kebiasaan merokok, hubungan seksualm perilaku seks menyimpang dan konsumsi alkohol. Berdasarkan hal tersebut peneliti tertarik untuk meneliti faktor risiko kanker prostat di poliklinik bedah urologi RSUP H.Adam Malik, Medan Metode: Jenis penelitian yang dilakukan adalah survey analitik dengan menggunakan pendekatan retrospektif. Lokasi penelitian adalah di Poliklinik Bedah Urologi RSUP H.Adam Malik, Medan., dengan populasi kasus adalah penderita kanker prostat yang didiagnosis secara klinis, sebanyak 42 orang, populasi kontrol adalah yang tidak terdiagnosis Kanker Prostat atau kanker lainnya Hasil: Hasil analisis bivariat menunjukkan bahwa faktor-faktor yang berpengaruh terhadap kanker prostat meliputi riwayat keluarga (p=0,024, p<0,05) , kebiasaan merokok (p=0,041, p<0,05) dan riwayat penyakit sebelumnya (p=0,020, p<0,05). Faktor-faktor yang tidak berpengaruh terhadap kanker prostat meliputi obesitas (p=0,612,p>0,05), kebiasaan merokok (p=0,739, p>0,05), riwayat hubungan seksual (p=0,795, p>0,05) dan riwayat perilaku seks menyimpang (p=1,000, p>0,05). Kesimpulan: Dari hasil penelitian dapat disimpulkan bahwa terdapat hubungan antara riwayat keluarga, kebiasaan mengkonsumsi alkohol dan riwayat penyakit sebelumnya terhadap kejadian penyakit kanker prostat di poliklinik bedah urologi RSUP H.Adam Malik, Medan.
UJI EFEKTIVITAS EKSTRAK RIMPANG KUNYIT TERHADAP BAKTERI BACILLUS CEREUS DENGAN PEMBANDING CIPROFLOXACIN Risyad Rizki Maulidi; Novita Helshinta Dewi Pangaribuan; Frisdayanti Br Ginting; Princessa Fath Sheridan; Yolanda Eliza Putri Lubis
Biospecies Vol. 13 No. 1 (2020): Biospecies Vol. 13 No. 1, January 2020
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.703 KB) | DOI: 10.22437/biospecies.v13i1.8389

Abstract

This research aims to find out effectiveness test of turmeric rhizome in concentration of 25%, 50%, 75% and 100% toward Bacillus cereus bacterial and Ciprofloxacin the same concentration as the comparison. Bacillus cereus Bacteria is a gram-positive rod-shaped bacteria and it is dangerous for humans. This research was conducted with an experimental method with post-test only design and sampling using purposive sampling method. The effectiveness test of turmeric rhizome extract toward Bacillus cereus bacteria was carried out by diffusion using disc paper by calculating the diameter of the bacterial inhibition zone against disc paper that had been moistened with turmeric rhizome extract or Ciprofloxacin solution. The results obtained in this research were carried out with the Post Hoc test, the test was found that there were significant differences from each treatment given with a 95% confidence index. In bacteria treated with 25% ciprofloxacin toward Bacillus cereus, the effectiveness was above 50% turmeric rhizome extract and under 75% turmeric extract. Turmeric extract of 75% 10.6 mm had bacterial effect as Ciprofloxacin 25% of 10.1 mm toward the growth of Bacillus cereus bacterial.
- Uji Efektivitas Ekstrak Bunga Pepaya (Carrica papaya L.) Terhadap Kadar Gula Darah Mencit (Mus musculus L.) Jantan Yang Diinduksi Sukrosa: Uji Efetivitas Ekstrak Bunga Pepaya (Carrica Papaya L.) Terhadap Kadar Gula Darah Mencit (Mus Musculus L.) Jantan Yang Diinduksi Sukrosa Febri Sri Marpaung; Ester Juanita br. Tampubolon; Muhammad Insan Andika; Yolanda Eliza Putri Lubis; Maya Sari Mutia
Biospecies Vol. 14 No. 1 (2021): Biospecies, January 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11175

Abstract

The papaya (Carica papaya L) flower contain flavonoids, tannins, and triterpenoid steroids which function as antidiabetic. This study was conducted to determine the antidiabetic effect of papaya (Carica papaya L) flower extract on sucrose-induced male mice. In this study, mice were made diabetic by inducing them with sucrose at a dose of 160 mg/kg BW. A total of 25 mice were grouped homogeneously into 5 groups, consisting of a negative control group (CMC 0.5%), a positive control group (no administration), a group with a dose of 200 mg/kg BW, a group with a dose of 400 mg/Kg. BW, and the group with a dose of 500 mg/Kg BW. Measurement of blood sugar levels of mice was carried out before administration of sucrose, after administration of sucrose and after administration of papaya flower extract. The results showed that the three doses had an antidiabetic effect, and the administration of papaya flower extract at a dose of 200 mg/Kg BW showed a better effect than the negative control.
- Uji Efektivitas Ekstrak Etanol Kulit Jeruk Sunkist (Citrus sinensis (L.) Osbeck) Terhadap Kadar Gula Darah Tikus Wistar (Rattus norvegicus) dengan Hiperkolesterolemia yang di Induksi Streptozotocin. : UJI EFEKTIVITAS EKSTRAK ETANOL KULIT JERUK SUNKIST (Citrus sinensis (L.) Osbeck) TERHADAP KADAR GULA DARAH TIKUS WISTAR (Rattus norvegicus) DENGAN HIPERKOLESTEROLEMIA YANG DI INDUKSI STREPTOZOTOCIN Sania Angelisa F Depari; Daffa Jihan Azmi Rambe; Rifki Meilando; Cut Lisya; Maya Sari Mutia; Yolanda Eliza Putri Lubis
Biospecies Vol. 14 No. 1 (2021): Biospecies, January 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11250

Abstract

The Condition of high blood sugar levels in people with diabetets appears to trigger an increase in LDL and decrease HDL level where in people with diabetes the energy obtained by the body comes from the decomposition of fat and protein metabolism.‚ÄĚSunkist orange peel (Citrus sinensis (L.) Osbeck) is reported to have antidiabetic, anti-hypercholesterolemia, anti-inflammatory and antioxidant activities. This study aims to find out the effectiveness of Sunkist orange peel ethanol extract (Citrus sinensis (L.) Osbeck) on blood sugar levels at doses of 500, 750 and 1000 mg/kgBB. This study used the True Experimental Pre-Test and Post-Test Control Group as research design where sunkist orange peel was extracted by maceration method and was given orally for 14 days to streptozotocin induced wistar rat with hypercholesterolemia. Statistical test results showed that ethanol extract of Sunkist orange peel was able to lower blood sugar levels and cholesterol levels of h streptozotocin induced wistar rat with hypercholesterolemia (p<0.05). The most effective dose of Sunkist orange peel ethanol extract in lowering blood sugar levels and cholesterol levels of streptozotocin induced wistar rat with hypercholesterolemia is 1000mg/kgBB.