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All Journal E-Jurnal Medika Udayana Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Ida Bagus Ngurah
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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EFEKTIFITAS EKSTRAK ETANOL BIJI BESERTA ARIL BUAH DELIMA (Punica granatum l.) MENGHAMBAT PERTUMBUHAN BAKTERI Staphylococcus epidermidis SECARA IN VITRO Ida Bagus Budha Dharma Kusuma; Ida Bagus Ngurah; , Bagus Komang Satriyasa
E-Jurnal Medika Udayana Vol 9 No 6 (2020): Vol 9 No 06(2020): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.818 KB) | DOI: 10.24843/MU.2020.V09.i6.P09

Abstract

ABSTRAKInfeksi nosokomial telah mengalami peningkatan seiring waktu dan bakteri Staphylococcus epidermidis merupakan salah satu bakteri yang sering menyebabkan infeksi nosokomial tersebut.Tanaman delima dipercaya memiliki aktivitas antimikroba dan di Bali tanaman ini merupakantanaman hias di pekarangan. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak etanol bijibeserta aril buah delima (Punica granatum L.) menghambat pertumbuhan bakteri Staphylococcusepidermidis secara in vitro. Penelitian ini merupakan penelitian eksperimental murni denganrancangan post test only control group design. Sampel dibagi menjadi 2 kelompok yakni kontrol danperlakuan yang dibagi atas empat kelompok berdasarkan konsentrasi. Sampel bakteri Staphylococcusepidermidis didapat dari Lab. Mikrobiologi FK UNUD. Penelitian ini menunjukkan bahwa ekstraketanol biji beserta aril buah delima memiliki potensi sebagai penghambat pertumbuhan bakteri S.epidermidis dengan konsentrasi hambat minimum adalah konsentrasi 25% dan zona hambat terbesardihasilkan pada konsentrasi ekstrak 100%. Kata Kunci: Antimikroba, Zona Hambat, Staphylococcus epidermidis, buah delima
UMBI UBI JALAR UNGU BALI (Ipomoea batatas) DI TRANSAMINASE SERUM, MALONDIALDEHIDE HEPAR DAN ALKOHOL KRONIS I Wayan Putu Sutirta-Yasa; I Made Jawi; Ida Bagus Ngurah; Anak Agung Ngurah Subawa
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 17, No 3 (2011)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v17i3.1170

Abstract

Oxidative stress as a consequence of chronic alcoholic intake causes lesions of liver tissue. The objective of this study was to identifythe antioxidant effect of ethanol extract derived from Balinese purple sweet potato on the liver tissue in mice after chronic consumptionof alcohol. Subjects of this study were 32 adults male Swiss mice (12–14 weeks) divided into 4 groups with control group post-testonly design. Post-treatment of blood and liver samples were collected from each group of 8 mice. The MDA liver was quantified withthiobarbituric acid reactive substances (TBARS) method. Samples were collected from control group of 8 mice without sweet potatoextract and alcohol, 8 mice with 1 mg extract of Balinese purple sweet potato, 8 mice with 0.8 gram alcohol, and 8 mice with combineof alcohol and extract of Balinese purple sweet potato, each treatment was carried out every day for 4 weeks. The results showed asignificant increase of serum SGOT, SGPT and liver MDA level, after chronic consumption of alcohol (p = 0.00). The decrease of serumSGOT, SGPT and liver level MDA was significant in the group with extract of Balinese purple sweet potato (p = 0.00). The researchersconcluded that the extract of Balinese purple sweet potato had an antioxidant effect in mice which consumed alcohol chronically. Basedon this study it is concluded that extract of Balinese purple sweet potato has a protective effect on the liver cell in mice which consumedalcohol chronically.
Co-Authors Anak Agung Ngurah Subawa Bagus Komang Satriyasa I Made Jawi I Wayan Putu Sutirta Yasa Ida Bagus Budha Dharma Kusuma