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All Journal Medical Journal of Indonesia Makara Journal of Health Research
Purnawan Junadi
Departemen Administrasi Kebijakan Kesehatan Fakultas Kesehatan Masyarakat Universitas Indonesia
Medicine & Pharmacology

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The Sensitivity and Specificity of a new Scoring System Using High Resolution Computed Tomography to Diagnose Lung Cancer Abdullah, Arman A.; Bujang, Nurlela; Badril, Cholid; Hamdani, Chairil; Junadi, Purnawan; Jusuf, Anwar; Waspadji, Sarwono
Medical Journal of Indonesia Vol 18, No 3 (2009): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (549.769 KB) | DOI: 10.13181/mji.v18i3.360

Abstract

Aim To find a non-invasive diagnostic method for lung cancer with the results almost as accurate as histopathological examinations using HRCT scoring system.Method This study was conducted from December 2006 until March 2008. A total of 55 persons, comprised of 40 male and 15 female patients suspected of having lung cancer, underwent high resolution computed tomography with and without contrast as well as CT-guided transthoracic needle aspiration to obtain cytology specimens.Results Histopathological examinations revealed the existence of lung cancer in 43 patients (78%) and benign lesions in 12 patients (22%). A scoring system was then made based on the similarities of findings from CT and histopathologic examinations. In the the age group of 49 years and above, tumor volume of more than 68 cm3, HU of more than 21, spicula positive, angiogram positive and lymph node positive had a value of respectively 20, 19, 10, 24, 18, and 17 (total score 108).Conclusion This new method to diagnose lung cancer is constantly as accurate as histological findings with a sensitivity of 97.7% and a specificity of 83,3% and a cut-off score of 35. According to this system, a score of less than 35 indicates that the lesions were benign while a score higher than 35 is suggestive malignant. (Med J Indones2009;18:179-86)Key word: High resolution CT; Lung cancer; Scoring
Socio-Economics of Childhood Pulmonary Tuberculosis with Adult Tuberculosis Household Contacts in Daerah Istimewa Yogyakarta Province Asyary, Al; Junadi, Purnawan; Purwantyastuti, Purwantyastuti; Eryando, Tris
Makara Journal of Health Research Vol. 21, No. 3
Publisher : UI Scholars Hub

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Background: Since the tuberculosis (TB) disease in children constitutes a global health problem that has long been neglected, this study sought to predict socioeconomic factors as public-health determinants that could protect children who were exposed to TB in their household. Method: A case-control study of 132 children (under 14 years old) who shared their household with adults suffering from pulmonary TB was conducted in the Province of Daerah Istimewa Yogyakarta. This study consisted of an interview and anthropometry measurement for the controls screening test, while the cases were monitored by pediatricians with a scoring system childhood TB diagnosis from the secondary hospital database. A multiple logistic regression was used to analyze the results. Results: A healthy housing condition, predicted by a naturally illuminated luminary bedroom prevented the incidence of the childhood TB disease (p = 0.043) even if exposed to adult TB in their environment (p = 0.775). Conclusions: Healthy housing factors with good sunlight protected children especially at the early stage, when there were active pulmonary TB adult household contacts. Ventilation and morning sunlight facilitated air circulation, vitality and the body’s immune system towards TB protection.
Co-Authors Al Asyary Anwar Jusuf Arman A. Abdullah Chairil Hamdani Cholid Badril Nurlela Bujang Purwantyastuti Purwantyastuti Sarwono Waspadji Tris Eryando