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Efektivitas Pemberian Ekstrak Daun Jati Belanda (Guazuma Ulmifolia Lam) terhadap Kadar CRP pada Tikus Wistar Model Kontusio Pulmonum Nadhif, Aufa Muhammad; Kamaluddin, M. T.; Theodorus, Theodorus
Sriwijaya Journal of Medicine Vol. 3 No. 1 (2020): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Guazuma ulmifolia Lam is a plant with high flavonoid and phenol content. Both of these substances can provide antioxidant effects that are good for the treatment of pulmonary contusions. The aim of the study was to determine the efficacy of Guazuma ulmifolia Lam leaves extract on CRP levels in wistar rats in pulmonary contusion models. In vivo study, pre-post test only has been done in Animal House Faculty of Medicine Sriwijaya University in the period from November to December 2019. There were 25 male Wistar strain rats and divided into five groups, each group consisting of five mice. Mice are induced pulmonary contusions by dropping a load from a certain height. after that, rat blood was taken to be examined for pre-treatment CRP levels. Rats were treated according to the group for 48 hours, then their blood was taken to be examined for post-treatment CRP levels with ELISA. Data was analyzed using SPSS version 25. The rats weight and CRP levels are homogen. Guazuma ulmifolia Lam leaves extract showed significant results in reducing CRP levels in all groups compared with the control group.. The administration of the Guazuma ulmifolia Lam leaves extract (Guazuma ulmifolia Lamk) in rats with pulmonary contusions can reduce serum CRP levels.
Water quality and water borne diseases in lowland ecosystem of Banyuasin, South Sumatra, Indonesia Dianita Ekawati; Tan Malaka; Robiyanto H. Susanto; M. T. Kamaluddin; Dwi Setyawan
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 1, No 1 (2011): Life Sciences
Publisher : Syiah Kuala University

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Abstract

Water quality and quantity is always an important issue in lowland ecosystem of Banyuasin. Low domestic water supply sanitation is considered as having an important contribution on the high frequency of waterborne diseases in the area. The study aims at recording water borne diseases and the water quality in the lowland area of Banyuasin District. This field research was conducted using a cross-sectional method. Total samples were 210 households in Telang which were observed during July through August 2011. Six water samples were measured for their physical and chemical properties, in addition to 1 water sample for bacteriological test. All respondents used river water for sanitary purposes and 41.4% of them also have dug wells. Those who used river water for sanitation, 68.5 % also consumed purified water for drinking purpose. All water samples are acidic (pH 5,68-6,19) and contain high Iron  (1-26,269 Mg/L). Water has yellowish color.  The major disease are diarrhea and skin diseases. In the lowland area with the estuarine ecosystem water quality and scarcity are serious problems. This in turn causes the high prevalent of waterborne diseases such as diarea. Low level of education and socio-economic status make it difficult for the local people to overcome these problems. Outside intervention especially government so as to improve the condition is needed