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Pitarah Manusia Nusa Tenggara Timur Berdasarkan Ceritera Kromosom Y Meti OFI Tefu; Ferry Fredy Karwur
Scientiae Educatia: Jurnal Pendidikan Sains Vol 6, No 2 (2017): December (2017)
Publisher : Tadris Biologi Fakultas Ilmu Tarbiyah dan Keguruan IAIN SYEKH NURJATI CIREBON

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (855.938 KB) | DOI: 10.24235/sc.educatia.v6i2.1622

Abstract

STUDY OF HUMAN ANCESTORS NUSA TENGGARA TIMUR INDONESIA BASED ON Y CHROMOSOME.Genetic studies conducted in NTT region focused on four islands namely Flores, Sumba, Alor, and Timor. The islands of NTT are a transition zone between Papuan and Austronesian speakers. Genetically there is also an intensive mixing. The dominant genetic of tribes in Alor island is Papua / Melanesia, but on the other islands there is almost uniform mixing. In the western part of Sumba Island there is a majority area of the Papuan/ Melanesian genetic type, while the tribes in eastern Sumba, Sabu and Rote are Austronesian. Genetic mixing is also seen on Timor Island. West Timor is the more dominantly Austronesian type, while central and eastern Timor are a mixture of Papua/ Melanesia with Austronesian. On such Flores islands, the tribes in the eastern and central regions have the Papua/ Melanesian type, while the western part is almost entirely of Austronesian type. The tribes on Solor, Lembata and Adonara Islands also have mixed types between Austronesia and Papua/ Melanesia. Based on paternal lineage, the blood flowing in NTT people consists of seven line ages of East Asia, Taiwan, Southeast Asia, Arab, Japan, Europe and Papua/ Melanesia, characterized by the detection of thirty-two Y-DNA markers: C-M130/ RPS4Y, F-P14/F-M89 (East Asia), NO-M214, O-M175, O-M119, O-M95, O-P203, O-M110, O-M122, O-M134, O-P201, O-JST3002611 (Taiwan), K-M526, K-P397, K-P405, K-P79, K-P336, P-P295, Q-M242, Q-P36 (Southeast Asia), J-M172 (Arab), C-P343, D-M116 (Japan), E-P1 (Europe),C-M38, C-M208, C-P355, M-P256, M-M4, M-P34, S-M230, S-M254, S-P377 (Melanesia).Studi genetik yang dilakukan di daerah NTT difokuskan pada empat pulau yakni Flores, Sumba, Alor, dan Timor. Pulau-pulau di NTT menjadi zona transisi antara penutur Papua dan Austronesia. Secara genetika juga terjadi pembauran yang intensif. Suku di pulau Alor, genetiknya dominan Papua/ Melanesia, namun di pulau-pulau lain terjadi pembauran hampir merata. Di Pulau Sumba bagian barat ada kawasan yang genetikanya mayoritas bertipe Papua/ Melanesia, sedangkan suku di Sumba bagian timur, Sabu dan Rote bertipe Austronesia. Pembauran genetika juga terlihat di Pulau Timor. Timor barat lebih dominan bertipe Austronesia sedangkan Timor bagian tengah dan timur merupakan campuran Papua/ Melanesia dengan Austronesia. Di pulau florespun demikian, yakni suku-suku di bagian timur dan tengah memiliki tipe Papua/ Melanesia, sedangkan bagian barat hampir seluruhnya memiliki tipe Austronesia. Suku-suku di pulau Solor, Lembata dan Adonara juga memiliki tipe campuran antara Austronesia dan Papua/ Melanesia. Berdasarkan garis keturunan ayah, darah yang mengalir dalam orang NTT terdiri atas tujuh garis keturunan yaitu Asia Timur, Taiwan, Asia Tenggara, Arab, Jepang, Eropa dan Papua/ Melanesia, yang ditandai dengan terdeteksinya tiga puluh tiga penanda Y-DNA yakni: C-M130/ RPS4Y, F-P14/F-M89 (Asia Timur), NO-M214, O-M175, O-M119, O-M95, O-P203, O-M110, O-M122, O-M134, O-P201, O-JST3002611 (Taiwan), K-M526, K-P397, K-P405, K-P79, K-P336, P-P295, Q-M242, Q-P36 (Asa Tenggara), J-M172 (Arab), C-P343, D-M116 (Jepang), E-P1 (Eropa),C-M38, C-M208, C-P355, M-P256, M-M4, M-P34, S-M230, S-M254, S-P377. (Melanesia) 
Efek Beta Karoten dan Agregasi Klorofil Pada Fotostabilitas Klorofil a dalam Pelarut Aseton Costa, Junet. F. da; Karwur, Ferry F; Limantara, Leenawaty
Jurnal Natur Indonesia Vol 11, No 2 (2009)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.132 KB) | DOI: 10.31258/jnat.11.2.115-123

Abstract

Chlorophyll as photosynthetic pigment has many benefits to human such as antioxidant, antibacterial, color additive,immunity, and photosensitizer. Concerning to these applications, chlorophyll a will react with oxygen and light andreduce its effectiveness. It is then important to understand the stability of chlorophyll a on oxygen and light.Stability of chlorophyll a in the presence of beta-carotene (1:1) in acetone was studied for various waterconcentrations. Each solution was exposed to red light (ë e” 630 nm) for 0.5; 1.0; 2.5; 5.0; 10; 20; 30; 40; 50; and 60minutes and their spectrum were analysed. When water was added (8.33; 16.67; 25; 33.33; 41.67; 50; 58.33; 66.67;75; and 83.33 percent) to the acetone solution of chlorophyll a, the chlorophylls aggregate, and in the presence ofbeta-carotene, the chlorophyll more stable. The water shifts the chlorophyll a spectrum toward red duringillumination with or without the presence of carotene. The formation of oligomeric chlorophyll a aggregate occurswithin 10-20 minutes after the water was applied. This strategy of aggregating the chlorophylls to dissipateexcess energy captured from light does not support the photostability of chlorophyll as much as beta-carotene.Surprisingly, when beta carotene was mixed with 66.7% and 75.0% of water, the chlorophyll a degraded 5.56% and9.71% respectively. In conclusion, the aggregate form of chlorophyll a and the presence of beta-carotene increasephotostability of chlorophyll a in acetone solution.
Analisis Komposisi dan Kandungan Karotenoid Total dan Vitamin A Fraksi Cair dan Padat Minyak Sawit Kasar (CPO) Menggunakan KCKT Detektor PDA Syahputra, M. Rio; Karwur, Ferry F; Limantara, Leenawaty
Jurnal Natur Indonesia Vol 10, No 2 (2008)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (684.953 KB) | DOI: 10.31258/jnat.10.2.89-97

Abstract

This study was carried out on two phases of Crude Palm Oil (CPO) to determine the total and composition ofcarotenoid and vitamin A content. Total of carotenoid was analyzed using spectrophotometer UV-Vis, and then theresult was calculated by Gross (1991) equation. The vitamin A content was calculated by NAS-NRC equation (1974).The type and composition of both phases of CPO were determined by Choo’s method (1994) by using HPLC withPhoto Diode Array (PDA) detector. The sample was prepared in two methods, with and without saponification. Theresult shows that total carotenoids in liquid and solid phase of CPO are 536 ± 13.2 g/g (liquid), 352 ± 17.7 μg/g(solid) and the vitamin A were 89.4 ± 2.2 RE (liquid), 58.7 ± 3.0 RE (solid), respectively. The carotenoid compositionsof both phases of CPO were dominated by - and -carotenes. The result shows that - and -carotenes preparedby saponification method in liquid phase are 29.03% and 60.88%, and without saponification (direct method) are28.14% and 59.44%. The result for solid phase shows that - and -carotenes by saponification are 25.89% and60.81%, and without saponification (direct method) are 30.00% and 56.92%. The research also shows the advantagesof using HPLC with PDA detector for identification and analysis of type and carotenoid composition.
Perkembangan Sensitizer pada Terapi Fotodinamika Tumor dan Kanker Hingga Penuntunan Nanopartikel (Nanoparticulate Targeting) Dengan Antibodi Monoklonal INDRAWATI, RENNY; KARWUR, FERRY F; LIMANTARA, LEENAWATY
Indonesian Journal of Cancer Vol 4, No 3 (2010): Jul - Sep 2010
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

World Health Organization (WHO) estimates both the number of patients and mortality rates due to cancer will continue to rise. Various researches were conducted in order to prevent and handle the cases of tumors and cancers, including the application of photosynthetic pigment molecules known as photodynamic therapy (PDT). Chlorophylls, the main pigment in photosynthesis, have an ability to capture light energy and control series of photobiology and photochemical processes1. In PDT, chlorophyll or its derivatives compounds act as the sensitizer which have energy excitation by light radiation (visible or near infra red), and generate some reactive oxygen species which triggers the death of cancer cells selectively (through apoptosis and / or necrosis pathway)2. Sensitizer compounds have been progressing from the first to third generation. The development of the third generation sensitizer was influenced by the advances of nanotechnology which lead to the improvement of PDT efficacy. The structure and size of nanoparticles can increase light absorption, and make the sensitizer accumulate in cancer tissues more specifically 3-4. Furthermore, nanoparticulatte targeting also interested to be studied because by conjugate functional groups, i.e. monoclonal antibody, on the sensitizer, it can improve the selectivity of therapy in targeting tumor and cancer tissues.
THE RELATIONSHIP BETWEEN OF HYPERURICEMIA WITH HYPERGLYCEMIA IN JAVANESE MEN Karwur, Ferry Fredy; Pujiastuti, Dwi Rahayu
Jurnal Ilmu Kesehatan Masyarakat Vol 8, No 3 (2017): Jurnal Ilmu Kesehatan Masyarakat
Publisher : Faculty of Public Health Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (647.3 KB)

Abstract

Background: The prevalence of degenerative diseases, especially metabolic diseases in Indonesia in the last 10 years is increasing. Studies of the linkage between hyperuricemia and hyperglycemia have been reported in a clinical context and very limited in a populative context. This study was aimed at analyzing the prevalence of hyperuricemia in Javanese men, by analyzing the relationship between uric acid, Fasting Plasma Glucose, and other anthropometric factors that affect Javanese older males in Central Java, Indonesia. Methods: The study was conducted by cross-sectional study of men from the general population in Ngebung village (Sragen, Central Java) aged ≥ 50. The sample size of 108 people came from the total population of men aged ≥ 50 of 359 people ( 30%) in the village (Total number of male population in the village is 1133). Measurements include blood uric acid levels, fasting blood glucose, anthropometry (height, weight, waist circumference, and hip). The data were analyzed using Kruskal-Wallis, Spearman, and Binary Logistic Regression statistics. Results: The results showed that the prevalence of hypouricemia reached 2.8%, normal 46.3%, and hyperuricemia 50.9%. Meanwhile, the prevalence of hypoglycemia was 3.7%, normoglycemia 49.1%, and hyperglycemia 47.2%. The concentration of uric acid had a positive correlation with BMI (r=0.204, p < 0.05), FPG (r=0.184, p ≥ 0.05), and WHR (r=0.107, p > 0.05), but the age variable had a negative correlation (r=-0.016, p > 0.05). After adjusting the age, WHR, and BMI variables, odds ratio showed that hyperuricemia people were 0.29 likely to suffer from hyperglycemia (confidence interval [CI] 95%, 0.12–0.69, p < 0.05). Conclusions: Therefore, it could be concluded that the older men in that village had a high average of uric acid concentration (50.9% respondents ≥ 7 mg/dL) and hyperuricemia had a positive correlation with hyperglycemia.Keywords: Relationship, hyperuricemia, hyperglycemia, Javanese DOI: 10.26553/jikm.2017.8.3.160-168 
KOMPARASI MORFOLOGI BEBERAPA KOLONI JAMUR AKAR PUTIH (Rigidoporus microporus) DARI PERKEBUNAN KARET DI JAWA TENGAH DAN SUMATERA SELATAN Im Toy, Binerd Anthon; Langkuin, Jerry F.; Karwur, Ferry F.; Setyawan, Budi; Berlian, Intan; Rondonuwu, Ferdy S.; Martosupono, Martanto; da Costa, Junet F.
Jurnal Penelitian Karet JPK : Volume 36, Nomor 2, Tahun 2018
Publisher : Pusat Penelitian Karet - PT. Riset Perkebunan Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22302/ppk.jpk.v36i2.562

Abstract

Rigidoporus microporus adalah jamur yang menyebabkan penyakit jamur akar putih (JAP) pada tanaman karet. Tingkat keparahan penyakit yang ditimbulkan oleh JAP berbeda antar wilayah. Penelitian ini bertujuan untuk mengetahui komparasi morfologi beberapa koloni jamur akar putih  dari perkebunan karet di Jawa Tengah dan Sumatera Selatan. Sampel dikoleksi langsung dari perkebunan Merbuh dan Blimbing di Jawa Tengah dan Balai Penelitian Karet Sembawa di Sumatera Selatan. Penelitian dilakukan pada bulan November 2016-April 2017 di Laboratorium Carotenoid Antioxidant Research Center (CARC)  Universitas Kristen Satya Wacana, Salatiga. Hasil yang diperoleh menunjukkan bahwa kecepatan pertumbuhan ke-17 isolat berdasar penambahan diameter koloni hingga mencapai tepi petri bervariasi yaitu 4 hari (MB8), 6 hari (MM6), 7 hari (MK2, MK3, SS1), 8 hari (MK1, MM5, MM7, SS2, SS3), 9 hari (BW1, SS5), 10 hari (MK4, BW4, SS4), 11 hari (BW2), dan 13 hari (BB3). Morfologi koloni dan hifa JAP baik dari Jawa Tengah maupun Sumatera Selatan hampir sama, yakni koloni berbentuk bulat, filamentous, elevasi ada yang rata (flat) dan ada yang sedikit timbul (raised), serta berwarna putih hingga putih gading. Hifa JAP memiliki septa, hialin, bercabang, dan tidak ada clamp connection.
Konsumsi, Status Gizi, Dan Profil Kimiawi-Klinis Mahasiswa UKSW Etnis Dayak Ngaju Karwur, Ferry Fredy; Agustina, Venti; Desi, Desi; Leviano, Leviano
Jurnal Keperawatan Muhammadiyah Vol 5, No 1 (2020): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jkm.v5i1.4241

Abstract

Background: Nutrition issues in students mostly happen is a life changes phase that affected by lifestyle, so it could affected the behavior that tend to be unhealthy such as smoking, alcohol consumption, hyper-consumption, lack of physical activities and sleepless. This Unhealthy lifestyle potentially caused disease such as metabolic disorders. Therefore this research aim to find out the consumptions, nutritional status and chemical clinical profile and it correlation between nutritional status, anthropometry with chemical/clinical variable in UKSW students with Dayak ngaju ethnic background. This research used cross sectional observational design. Method: The number of respondents were 30 dayak ngaju ethnic students who lived in Salatiga. Data collection techniques using anthropometry measurements, chemical/clinical examination. Food frequency and food recall. Results: The result of anthropometry measurement and metabolic the 30 students showed, underweight 1 respondent (3,3 %), overweight 4 respondent (13,3%) low diastolic pressure (33,3 %), uric acid levels of 30 students is normal (100 %). 3 students with high cholesterol levels (10 %) and 6 students with high momentary glucose levels (20 %). Students nutritional intake using food recall 24 hours showed average energy consumption ±1527.44 kcal, protein ±51.09 gr, Fat ±46.27 gr, carbohydrate ±238.63 gr. Fulfillment of nutrient intake by category adequacy mostly fit in either category, but there were respondents who fall into the category of medium and light the deficit of protein (10%; 0% of respondents), carbohydrate (3.3%; 3.3% of respondents). The Pearson correlation test shows that there is a correlation between cholesterol and supraliaca with a p-value of 0.002 (p≤0.05).
ANALISIS PERTUMBUHAN DAN PERKEMBANGAN BUAH PALA (Myristica fragrans) MENGGUNAKAN FUNGSI BOLTZMANN Dalengkade, Mario Nikolaus; Karwur, Ferry Fredy
BAREKENG: Jurnal Ilmu Matematika dan Terapan Vol 14 No 4 (2020): BAREKENG: Jurnal Ilmu Matematika dan Terapan
Publisher : MATHEMATIC DEPARTMENT, FACULTY OF MATHEMATICS AND NATURAL SCIENCES, UNIVERSITY OF PATTIMURA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/barekengvol14iss4pp619-626

Abstract

Buah yang berasal dari Myristica fragrans merupakan sumber minyak atsiri dengan nilai ekonomi tinggi. Penelitian mengenai buah M. fragrans selama ini hanya memfokuskan pada indentifikasi senyawa bioaktif, penerapannya, dan yield-nya. Tapi penyelidikan mengenai perubahan fisik yakni diameter buah belum adanya pengkajian. Sehingga dalam penelitian ini memfokuskan pada perubahan diameter buah menggunakan fungsi Boltzmann , dan penggunaan fungsi yang dimaksud menunjukan luaran berupa garfik sigmoid semilogaritma. Dari grafik tersebut mencirikan tiga fase perubahan kumulatif diameter. Fase pertama terjadi selama tiga minggu, fase ke dua delapan minggu, dan fase ketiga yakni dua minggu. Disamping itu interpretasi mampu menjelaskan sebab akibat perubahan diameter tersebut.
Pemisahan dan Identifikasi Isomer Tokotrienol dari Tokotrienol Rich Fraction (TRF) Lodu, Widiyasri; karwur, ferry fredy
Proceeding Biology Education Conference: Biology, Science, Enviromental, and Learning Vol 14, No 1 (2017): Proceeding Biology Education Conference
Publisher : Universitas Sebelas Maret

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Abstract

Palm oil is the largest agricultural product produced by Indonesia. Palm oil contains a large group of vitaminE which are tocopherol and tocotrienol which have been widely reported their efficacy in inhibiting the growthand development of diseases such as antioxidants, anti-cancer, cholesterol inhibitors, prevent premature aging,and cardioprotective effects. This study aims to segregate and identify the intensity of each isomer ofTocotrienol Rich Fraction (TRF). Segregation and identification are done through using columnchromatography, UV-visible spectrophotometer, and HPLC. The spectral pattern of TRF shows the presenceof tocotrienol isomers at wavelengths of 292-298 nm. Five spectra patterns identified with the highest intensitywere demonstrated by the γ-tocotrienol isomers at 10.86 min, δ-tocotrienol at the minute of 9.36, α-tocotrienolat the minute of 12:42, α-tocopherol at 21.11 and α-T1 at 17.35 with 0 intensity.
Aktivitas olahraga bulu tangkis dan respon perubahan asam urat darah usia produktif Angkit Kinasih; Ronaldo Lomi Djara; Ferry Fredy Karwur
Jurnal Keolahragaan Vol 9, No 2: September 2021
Publisher : Program Studi Ilmu Keolahragaan Program Pascasarjana Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jk.v9i2.43271

Abstract

Penelitian ini bertujuan untuk mengetahui ada tidaknya respon perubahan pada kadar asam urat akibat aktivitas olahraga bulu tangkis.  Desain penelitian ini adalah quasi eksperimen. Sampel yang digunakan sebanyak delapan responden dengan kriteria tertentu. Perlakukan aktivitas fisik dilakukan dua kali pada hari yang berbeda dengan 4 kali pengukuran kadar asam urat. Metode penelitian yang digunakan adalah repeated measure analysis. Ketika subyek diukur berulang kali dengan jumlah yang sedikit per percobaan maka repeated measures analysis dapat digunakan. Hasil penelitian menunjukkan bahwa perlakukan olahraga bulu tangkis memberikan respon perubahan yang signifikan terhadap perubahan kadar asam urat dengan nilai probabilitas sebesar 0,038. Hasil ini diperoleh dengan menggunakan uji Greenhouse-Geisser dimana asumsi normalitas dan homogenitas telah terpenuhi. Pada hasil uji marginal menggunakan pairwise comparisons, terdapat perbedaan yang signifikan pada rata-rata kadar asam urat 15 menit setelah olahraga dan jam 09.00 hari berikutnya, dimana terjadi penurunan sebesar 1,169 mg/dl. Olahraga bulu tangkis dapat menurunkan kadar asam urat yang ditandai dengan adanya penurunan sebesar 0,15 mg/dl pada jam 09.00 hari berikutnya dibandingkan dengan sebelum olahraga. Secara marginal, penurunan ini tidak signifikan secara statistik, namun olahraga bulu tangkis yang rutin dapat menjadi salah satu pilihan aktifitas fisik bagi yang ingin menurunkan kadar asam urat.The sports activity of badminton and responses to changes in blood uric acid at productive ageAbstractThis study aims to determine whether there was a response to changes in uric acid levels due to the physical activity of badminton. The design of this study is a quasi-experimental. The sample used in this study was eight respondents with certain criteria. Treat physical activity twice on different days with 4 measurements of uric acid levels. The method of this study is repeated measure analysis. When subjects are measured repeatedly, requiring fewer subjects per experiment, then repeated measures analysis can be used. The results showed that the treatment of badminton had a significant effect on changes in uric acid levels with a probability value of 0,038. These results were obtained by using the Greenhouse-Geisser test where the assumptions of normality and homogeneity were satisfied. From the marginal test results using pairwise comparisons, there was a significant difference in the average uric acid levels at 15 minutes after exercise and 9 hours the following day, where there was a decrease of 1.169 mg/dl. Badminton can reduce uric acid levels, which is indicated by a decrease of 0.15 mg/dl at 09.00 the next day compared to before exercise. Marginally, this decrease is not statistically significant, but regular badminton can be an option for physical activity for those who want to reduce uric acid levels.