Cholis Abrori, Cholis
Department Of Pharmacology, Faculty Of Medicine, University Of Jember, Indonesia

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The Density of Dermatophagoides sp. in Households and its Correlation with the Score for Allergic Rhinitis in Jember, East Java Sulistyaningsih, Erma; Laili, Elisa Fadia; Abrori, Cholis
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1: January 2021
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.7925

Abstract

The prevalence of allergic rhinitis (AR) in Indonesia is an estimated 24.3% and increasing each year. The majority cause of AR is house dust mites (HDMs) allergens, especially Dermatophagoides sp. The screening tool to estimate the prevalence and diagnose AF in a population setting is the Score for Allergic Rhinitis (SFAR) questionnaire. This study aimed to investigate the correlation between the density of Dermatophagoides sp. in households and the SFAR in Jember, East Java. The study enrolled 30 housewives as respondents, which were selected by stratified random sampling. Respondents were interviewed using the SFAR questionnaire. The dust sample from each house of the respondent was collected, the HDMs either Dermatophagoides sp. or others were identified and the density of Dermatophagoides sp. was calculated. Data were analyzed using the Pearson Test. Dermatophagoides sp. were found in 21 out of 30 samples and 11 out of 30 respondents had an SFAR of ≥ 7. The Pearson analysis showed the value of p = 0.555 and r = 0.136. Dermatophagoides sp. was the majority of species of HDMs, but there was no significant correlation between the density of Dermatophagoides sp. in households and the SFAR among housewives  in Jember.
The Density of Dermatophagoides sp. in Households and its Correlation with the Score for Allergic Rhinitis in Jember, East Java Sulistyaningsih, Erma; Laili, Elisa Fadia; Abrori, Cholis
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1 (2021): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.7925

Abstract

The prevalence of allergic rhinitis (AR) in Indonesia is an estimated 24.3% and increasing each year. The majority cause of AR is house dust mites (HDMs) allergens, especially Dermatophagoides sp. The screening tool to estimate the prevalence and diagnose AF in a population setting is the Score for Allergic Rhinitis (SFAR) questionnaire. This study aimed to investigate the correlation between the density of Dermatophagoides sp. in households and the SFAR in Jember, East Java. The study enrolled 30 housewives as respondents, which were selected by stratified random sampling. Respondents were interviewed using the SFAR questionnaire. The dust sample from each house of the respondent was collected, the HDMs either Dermatophagoides sp. or others were identified and the density of Dermatophagoides sp. was calculated. Data were analyzed using the Pearson Test. Dermatophagoides sp. were found in 21 out of 30 samples and 11 out of 30 respondents had an SFAR of ≥ 7. The Pearson analysis showed the value of p = 0.555 and r = 0.136. Dermatophagoides sp. was the majority of species of HDMs, but there was no significant correlation between the density of Dermatophagoides sp. in households and the SFAR among housewives  in Jember.
Perbandingan Peningkatan Kadar Malondialdehid (MDA) Serum setelah Olahraga Pagi dan Malam Hari pada Orang Tidak Terlatih Mushab Mushab; Hairrudin Hairrudin; Cholis Abrori
Jurnal Kesehatan Andalas Vol 9, No 2 (2020): Online June 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i2.1312

Abstract

Olahraga mampu meningkatkan kadar radikal bebas dalam tubuh melalui beberapa mekanisme yaitu peningkatan aktivitas mitokondria, NADPH, dan XO serta inflamasi pada sel otot rangka yang mengakibatkan stimulasi aktivitas fagosit. Olahraga yang dilakukan pada malam hari memiliki beberapa mekanisme tambahan sehingga berpotensi menyebabkan peningkatan kadar radikal bebas lebih tinggi, yaitu faktor pencetus radikal bebas yang meningkat pada malam hari. Salah satu indikator untuk mengetahui kadar radikal bebas dalam tubuh yaitu malondialdehid (MDA). Tujuan: Menentukan perbandingan antara peningkatan kadar MDA serum setelah olahraga pada dan malam hari pada orang tidak terlatih. Penelitian ini merupakan uji klinis dengan pre dan post-test group design. Metode: Sampel berjumlah  20 mahasiswa Fakultas Kedokteran Universitas Jember yang tidak terlatih, masing-masing berperan ganda sebagai kelompok pagi (Kp) dan kelompok malam (Km) sehingga jumlah total sampel sebesar 40. Olahraga yang dilakukan berupa sepeda statis dengan intensitas 70-80% dari heart rate maksimal. Setelah satu minggu dilakukan croosing-over, yaitu sampel Kp dijadikan Km begitu pula sebaliknya. Pengukuran kadar MDA dilakukan sebelum dan setelah olahraga menggunakan metode TBARS. Peningkatan kadar MDA merupakan selisih dari kadar MDA setelah dan sebelum olahraga. Hasil: Peningkatan kadar MDA setelah olahraga pada pagi dan malam hari adalah 0,29±0,87 nmol/mL dan 1,13±1,2 nmol/mL. Hasil uji statistik menunjukkan ada perbedaan yang signifikan p=0,021 (p<0,05). Simpulan: Peningkatan kadar MDA setelah olahraga pada malam hari lebih tinggi dibandingkan dengan peningkatan kadar MDA setelah olahraga pada pagi hari pada orang yang tidak terlatih.Kata kunci: malondialdehid, olahraga, radikal bebas, TBARS
Pengaruh Minuman Kopi Minim Kafein terhadap VO2max dan Pemulihan Denyut Nadi setelah Melakukan Treadmill (The Effect of Decaffeinated Coffee Drink on VO2max and Pulse Recovery Rate after Treadmill Test) Chikita R Hanifati; Cholis Abrori; M Ihwan Narwanto
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Coffee can be classified as a psicostimulant agent cause awakening, due to its content, such as caffeine. For intolerant person caffeine can be harmful, so nowadays created decaffeinated coffee. The purpose of this study was to determine the effect of decaffeinated coffee drink consumption on VO2max and pulse recovery rate after treadmill test. This was a quasi experimental study with Randomized Clinical Trial (RCT) methods. There were 20 volunteers, divided into two groups that swapping roles after 4 days washing out. The control group was given an instant coffee drink while the treatment group was given a decaffeinated coffee drink. All volunteers were asked to perform Modified Bruce Treadmill Test procedure until exhausted then VO2max were examined. The results showed the average value of VO2max in treatment group was +45,22 ml/kg/min and in control group +46,96 ml/kg/min from the previous study the value of VO2max using placebo was 25,98 ml/kg/min. Duration of pulse recovery rate in treatment group was 52 minutes faster than control group, 57 minutes. Analyses by T-test obtained p=0,23 mean there was no significant difference. In conclusion, decaffeinated coffee drinks could increased VO2max as the instant coffee did, but it still could accelerate pulse recovery rate. Keywords: Modified Bruce Treadmill, pulse recovery rate, VO2max, decaffeinated coffee
Pengaruh Minuman Kopi terhadap VO2max dan Pemulihan Denyut Nadi pasca Melakukan Treadmill (The Influence of a Coffee Drinks to VO2max and Pulse Recovery after Doing Treadmill) Natasha Amelia; Cholis Abrori; M Ihwan Narwanto
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Coffee can be classified as a psicostimulant which cause person stay awake. Coffee contains any ingredients such as caffeine.Caffeine could improve the performance of athletes. VO2max is a highest ratio of oxygen consumed during intense physical activity. The purpose of this study was to determine the effect of caffeine consumption on VO2max and exercise recovery pulse. The study used experimental research with Randomized Clinical Trial (RCT) methods. There were 20 volunteers, who were divided into two groups. The control group was given a drink that contains no caffeine while the treatment group was given a drink containing caffeine. Then all volunteers were asked to perform Modified Bruce Treadmill Test procedure until exhaustion occurred then VO2max.The next 4 days were washing out period where the control and treatment groups swap the roles. The results showed the average value of VO2max in the treatment group was 30.69 ml/ kg/min higher than in the control group 25.98 ml/ kg/min, but the duration of pulse recovery in the treatment group was 127 minutes slower than the control group, 121 minutes, indicating to its effects as a stimulant. In conclusion, administration of caffeine increased VO2max, but delayed time of pulse recovery.   Keywords: Modified Bruce Treadmill Test, pulse recovery, caffeine,VO2max
Kadar Puncak (Cmax), Waktu Puncak (Tmax), Waktu Paruh (T½) dan Bersihan Teobromin pada Sukarelawan Sehat setelah Pemberian Dark Chocolate Bar Per Oral Nyoman Defriyana Suwandi; Cholis Abrori; Muhammad Hasan
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7620

Abstract

Dark chocolate contains two derivates of metilxantin, I.e. caffeine (1,3,7-trimetilxantin) and theobromine (3,7 dimetilxantin). Theobromine can be found in plasma. Theobromine concentration in plasma determined not only by drug dosage but also by pharmacokinetic parameters. This research aimed to determine pharmacokinetic parameters by using HPLC (High Performace Liquid Chromatography) method. This study used Quasi Experimental Design by using 16 plasma samples collected at the 0, 1.5, 3, 6, 10, 24 hours. The pharmacokinetic parameter calculations were obtained from the polynomial curve and linear curve of drug concentration in plasma by time. The maximum concentration (Cmax) theobromine on plasma after consumption of dark chocolate bar per oral was 4.173 mg/L. The maximum time (Tmax) was at the 2.501 hours. The half time (t½) theobromine was 4.880 hours. Theobromine clearance in plasma was 14.2 ml/kg/hour. The study has reported pharmacokinetic parameters of theobromine in plasma after eating dark chocolate bars orally. Keywords: Chocolate, half-time, maximum concentration, maximum time, theobromine
Pengaruh Pemberian Natrium Bikarbonat terhadap Kelelahan dan Nyeri Otot setelah Melakukan Treadmill Fath Arina Fahma; Cholis Abrori; Hairrudin Hairrudin
Pustaka Kesehatan Vol 7 No 1 (2019): Volume 7 No. 1, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i1.17590

Abstract

Treadmill is a physical exercise that caused a metabolic transition from aerobic into anaerobic. The aim of this study was to determine the effect of sodium bicarbonate to reduce fatigue and muscle pain after treadmill. This study used a time-series design with 20 selected samples from undergraduate student population of the Faculty of Medicine, Jember University. Samples consumed 100mg/kgBW NaCl (placebo) and NaHCO3 300mg/kgBW then perform a treadmil protocol until it reached maximum muscle fatigue. The results showed that the average treadmill of the treatment group (778,1±121,21 seconds) was longer than control group (717,7±93,02 seconds). The intensity of acute pain as measured by VAS (Visual Analog Scale) treatment group was lower (44,7±22,47 units) than control (55,4±19,97 units). So this study inferred that NaHCO3 can reduce fatigue and acute pain intensity after treadmill.
Efektivitas Analgesik Kombinasi Parasetamol dan Ekstrak Kasar Nanas terhadap Refleks Geliat Mencit yang Diinduksi Asam Asetat (The Analgesics Effectivity of Combination of Paracetamol and Pineapple Crude Extract on Writhing Reflex in Mice Induced by Ace Fauqi Amalia; Cholis Abrori; Ika Rahmawati Sutejo
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Bromelain is a proteolytic enzyme which can be found in pineapple. The proteolytic activity of bromelain commonly used as an anti-inflammatory agent and antioedema, antithrombotic, and fibrinolytic agent. This study aimed at determining the combination effectivity of paracetamol and bromelain, pineapple crude extract’s protein, on pain response in mice and its interaction. This research used true experimental design with posttest only control group. Data analysis using Kruskal-Wallis test and application CompuSyn. The mice induced by acetic acid as the pain’s trigger and writhing reflex calculated every 5 minutes for 1 hour. The results of this study were expressed by pain protection persentage of paracetamol, crude extract of pineapple, a combination dose of paracetamol and crude extract of pineapple ½:½ and 1:1 was 52.23 ± 3.94%; 51.28 ± 6.71%; 77.88 ± 4.02%; and 71.24 ± 10.54%. The results of the CompuSyn dose combination analysis showed a synergistic effect that is seen from the CI value. In conclusion, analgesic effectivity combination of paracetamol and pineapple crude extract more effective than single dose usage and showed a synergistic effect. Keywords: analgesic, bromelain, pain, paracetamol, pineapple
Pengaruh Pemberian Jus Semangka terhadap Kelelahan Otot dan Delayed Onset Muscle Soreness setelah Latihan Beban (The effect of Watermelon Juice on Muscle Fatigue and Delayed Onset Muscle Soreness after Weight Training) Prayoga Adinawer Sirait; Cholis Abrori; Enny Suswati
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The main problem that is often faced by athlete is fatigue. It can decrease maximum muscle strength. To overcome this problem, many athletes use ergogenic aids such as watermelon. The purpose of this study was to determine the effect of watermelon juice on reduction of muscle fatigue and delayed onset muscle soreness (DOMS) after weight training. Muscle fatigue was measured by maximum repetition done by the subjects in the last set and DOMS was measured by post-training muscle soreness intensity. By using a randomized crossover design, 20 subjects were recruited then divided into 2 groups, a treatment group and a control group. The subjects were asked to do a training protocol to induce muscle fatigue and DOMS. As much as 500 ml watermelon juice was consumed in 1 of 2 training sessions and a placebo was consumed in the other. The number of repetitions showed a significant increase on treatment group than control group (p<0,05). Passive muscle soreness intensity and active muscle soreness intensity showed a significant decrease on 24 hours and 48 hours post-training after administration of watermelon juice (p=0,000). We conclude that there was an effect of watermelon juice on muscle fatigue and DOMS after weight training.   Keywords: weight training, muscle fatigue, DOMS, watermelon, citrulline
Pengaruh Pemberian Teh Hitam terhadap VO2max dan Pemulihan Denyut Nadi Pasca Melakukan Latihan Treadmill (The Effect of Black Tea on VO2max and Heart Rate Recovery Time after Treadmill Exercise) Yedi Murdanu; Cholis Abrori; Muhamad Hasan
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

In sports, caffeine is oftenly consumed as a stimulant in intense exercise. Caffeine consists in black tea with the content is about one third to eighth compared to black coffee, The aim of this research was to find out the effect of black tea to VO2max and heart rate recovery time after treadmill exercise. There were 2 groups. Control group which consumed placebo and treatment group which consumed black tea. Both group performed Bruce Treadmill Test Protocol. The results showed that the mean value of VO2max were 32,525 for control group and 38,442 for treatment group. Data analysis using T-paired test showed that treatment group had significantly higher VO2max value than control group (p=0,0001). Heart rate change data showed that heart rate frequency in treatment group from every fixed time was higher than the control group The heart rate recovery time was 59 minutes for control group and 66 minutes for treatment group. In conclusion, consumption of black tea before exercise would increase VO2max value and extend the heart rate recovery time.   Keywords: Black tea, VO2max, heart rate recovery, Bruce treadmill test protocol