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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Legalite: Jurnal Perundang Undangan dan Hukum Pidana Islam
Salinah Salinah
Unknown Affiliation
Religion Biochemistry, Genetics & Molecular Biology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health

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Peranan miRNA-200 dalam tahapan metastasis kanker Salinah Salinah; Puspita Eka Wuyung
JURNAL KEDOKTERAN DAN KESEHATAN Vol 6, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.v6i1.7238

Abstract

MikroRNA merupakan bagian dari keluarga besar non-coding RNA yang secara negatif meregulasi ekspresi gen pengkode protein paska transkripsi melalui pasangan basa antara 5’ seed region miRNA dengan 3’ untranslated region dari mRNA. Berbagai studi telah menunjukkan adanya peran penting miRNA pada perkembangan kanker. Keluarga miR-200 termasuk mikroRNA yang berperan dalam inisiasi hingga tahap metastasis kanker. miR-200 terdiri dari 5 anggota yaitu miR-200a, -200b, -200c, -141, dan -429. Keluarga miR-200 berperan pada tiap tahapan metastasis yaitu mulai dari pertumbuhan tumor, angiogenesis, invasi ke jaringan sekitar, transisi dari epitelial ke mesenkimal, migrasi sel tumor, intravasasi sel tumor, kemampuan survival sel tumor di dalam  sirkulasi, dan ekstravasasi sel tumor serta kolonisasinya.
PENERAPAN ASAS OPORTUNITAS DALAM HUKUM PIDANA DI INDONESIA DITINJAU DARI HUKUM ISLAM Salinah salinah
Legalite : Jurnal Perundang Undangan dan Hukum Pidana Islam Vol 1 No 1 (2016): Volume I No. 01 Tahun 2016
Publisher : IAIN Langsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32505/legalite.v1i1.292

Abstract

Law enforced one of them is to meet the sense of justice. Everyone is equal before the law. In the criminal procedure law we recognize several principles which one of them is the principle of opportunity. The principle of self-participation is not actually mentioned in the Criminal Procedure Code but is implied. Whereas if we look back at previous criminal cases, the principle of opportunism is real applied to some people who are considered influential in this country. Whereas whoever he is he does not have impunity, just like ordinary people. However, there are other considerations in enacting this principle. Which of these considerations is the Attorney-General's authority. Furthermore, if we look from the view of Islamic law, we clearly know that whoever it is, it is equal before God and His law.
Co-Authors Puspita Eka Wuyung