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All Journal Jurnal Gizi Klinik Indonesia Nutri-Sains: Jurnal Gizi, Pangan dan Aplikasinya Jurnal Dunia Gizi
Clara Meliyanti Kusharto
Departemen Gizi Masyarakat, Fakultas Ekologi Manusia (FEMA), Institut Pertanian Bogor, Bogor 16680
Health Professions Public Health

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Kromium serum dan asupan mikromineral pada penyandang diabetes tipe 2 Sutiari, Ni Ketut; Rimbawan, Rimbawan; Kusharto, Clara Meliyanti; Ascobat, Purwantyastuti; Effendi, Adi Teruna
Jurnal Gizi Klinik Indonesia Vol 13, No 4 (2017): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.01 KB) | DOI: 10.22146/ijcn.18883

Abstract

Background: Status of minerals such as zinc, magnesium, and chromium among diabetic patients are considered lower than non-diabetic peoples, both in the serum and intake. Some reviews show that those minerals contribute to carbohydrate metabolism among diabetic patients.Objective: This study aims to explore intake of zinc, magnesium, and chromium among DMT2 in Denpasar.Method: This is a cross-sectional analytic study. The population was all (70) DMT2 patients registered at Chronic Disease Service (Prolanis) at two Primary Health Care (PHC) Denpasar Utara III PHC and Denpasar Timur I PHC. The sample for the study was DMT2 patients and non-diabetic people age 50-70 years reside in Denpasar city. DMT2 patients were randomly selected with simple random technique, while non-diabetic peoples were non-randomly selected. The level of serum chromium was measured by AAS method, whereas microminerals intake were collected by a recall and SQ-FFQ method. Data was analyzed descriptively and differences were tested with two independent t-test at 95% confidence level.Results: The mean of serum chromium DMT2 and non-diabetic were 0.044 mg/L and 0.094 mg/L respectively. The mean±SEM magnesium (DMT2 316.1±22.4 mg/day; non-diabetic 211.0±33.5 mg/day), zinc intake was (DMT2 8.4±0.7 mg/day; non-diabetic 6.2±0.8 mg/day), and chromium (DMT2 10.8±1.3 µg/day; non-diabetic 8.7±0.9µg/day). A significant difference was found between magnesium intake (p=0.01).Conclusion: The study showed that zinc, magnesium and chromium intake is appeared higher among DMT2 patients compare to non-diabetic in Denpasar region.
PENGEMBANGAN CRACKERS SUMBER PROTEIN DAN MINERAL DENGAN PENAMBAHAN TEPUNG DAUN KELOR (Moringa oleifera) DAN TEPUNG BADAN-KEPALA IKAN LELE DUMBO (Clarias gariepinus) kustiani, Ai; Kusharto, Clara Meliyanti; Damayanthi, Evy
Nutri-Sains: Jurnal Gizi, Pangan dan Aplikasinya Vol 1, No 1 (2017)
Publisher : Universitas Islam Negeri Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/ns.2017.1.1.1912

Abstract

Kelor is one of the vegetables with high nutrients contents but haven’t been widely utilized. Adding kelor leaves flour to the crackers made with catfish flour to increase protein and minerals is one way to maximize the potential of its nutrient content. This research purposed to develop the formulation of crackers by adding kelor leaves flour and catfish dumbo flour as a food source of protein and minerals. Kelor leaves flour obtained from this research contains protein, calcium, iron, and zinc respectively for 23.25%, 640.5 mg/100g, 30.6 mg/100g, and 6.65 mg/100g. The best formula chosen from organoleptic was is crackers with the addition 10% catfish dumbo flour and 2.5 g kelor leaves flour. The crackers contain 11.50% protein, 30.73 mg/100g calcium, 8.56 mg/100g iron, and 609.70 mg/100g zinc respectively. Selected crackers contain more than 20% protein and more than 15% of iron and zinc standart for 2-5 years old children group based on nutrition label reference (ALG, for Indonesian), so it can be claimed as a food source of protein, iron and zinc. 
Pengaruh Minyak Ikan Lele terhadap Kerusakan Sel Saraf, Sel Hepatosit, dan Sel Ginjal Tikus Sprague Dawley Firmansyah, Hardi; Kusharto, Clara Meliyanti; Roosita, Katrin; Handharyani, Ekowati; Rosmiati, Risti
Jurnal Dunia Gizi Vol 4, No 1 (2021): Edisi Juni
Publisher : Study Program of Nutrition, Public Health Faculty, Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdg.v4i1.4749

Abstract

Pendahuluan; Minyak ikan lele (Clarias gariepinus) mengandung omega 3 dan omega 6 yang dapat menurunkan kadar trigliserida dalam darah dan memberikan efek positif terhadap jaringan hati. Tujuan; untuk menganalisis pengaruh pemberian minyak ikan lele terhadap jumlah sel saraf, sel hapatosit dan sel ginjal yang rusak pada tikus galur Sprague Dawley yang diberi pakan hiperkolesterolemia. Bahan dan Metode; Desain penelitian ini Randomized Control trial (RCT) pada hewan coba tikus galur Sprague Dawley dengan empat perlakuan yaitu A1 (kontrol), A2 (minyak ikan lele), A3 (minyak ikan lele + omega 3) dan A4 (minyak ikan lele+omega 3+vitamin E). Sel-sel yang mengalami abnormalitas dihitung di bawah mikroskop cahaya (pembesaran 20x40) untuk kemudian dianalisis univariat (rata-rata±standar deviasi) serta analisis bivariat (one-way ANOVA). Hasil; Rata-rata jumlah sel yang mengalami kerusakan pada sel saraf di hipokampus pada kelompok tikus kontrol (A1) tidak berbeda signifikan dibandingkan semua kelompok tikus yang diberikan minyak ikan lele (A2, A3, A4) (p0,05). Hasil serupa juga ditunjukkan pada rara-rata jumlah sel hepatosit dan sel ginjal yang rusak. Kesimpulan; Pemberian minyak ikan lele dengan komposisi berbeda tidak memberikan perbedaan signifikan pada kerusakan sel saraf, sel hepatosit, dan sel ginjal tikus galur Sprague Dawley.
Co-Authors Adi Teruna Effendi Ai Kustiani Ascobat, Purwantyastuti Ekowati Handharyani Evy Damayanthi Hardi Firmansyah Katrin Roosita Ni Ketut Sutiari Rimbawan , Risti Rosmiati