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M. Hanafi
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Social Sciences

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PENGEMBANGAN KURIKULUM PERGURUAN TINGGI AGAMA ISLAM M. Hanafi
Islamuna: Jurnal Studi Islam Vol. 1 No. 2 (2014)
Publisher : Madura State Islamic Institute (Institut Agama Islam Negeri (IAIN) Madura)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19105/islamuna.v1i2.572

Abstract

Pengembangan kurikulum Pendidikan Agama Islam adalah suatu proses kegiatan penyusunan, pelaksanaan, penilaian dan penyempurnaan kurikulum pendidikan agama Islam. Ada empat asas dalam pengembangan kurikulum yaitu asas filosofis, sosiologis, organisatoris dan psikologis. Selain itu, terdapat empat pendekatan dalam pengembangan kurikulum di antaranya, yaitu pendekatan subjek akademik, pendekatan humanistic, pendekatan teknologi, dan pendekatan rekonstruksi social. Untuk mening-katkan mutu PTAI, maka kurikulum yang diterapkan perlu terus dikembangkan dengan memperhatikan asas-asas pengembangan kurikulum di atas. Pengembangan kurikulum PTAI harus berbasis kompetensi, agar lulusannya memiliki kompetensi handal sesuai bidang garapannya.
ISOLATION AND ANTIBACTERIAL TEST OF GARLIC OIL A. T. Karossi; M. Hanafi; L. Sutedja
Jurnal Kimia Terapan Indonesia Vol 3, No 2 (1993)
Publisher : Research Center for Chemistry - LIPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3252.499 KB) | DOI: 10.14203/jkti.v3i2.271

Abstract

Garlic oil is known to have medicinal effect on hypertension, heart desease, anemia and various infections. The active principles are reported to be allicin, diallil disulfide, allilpropyl disulfide, scorduun, selenium and germanium in addition to the presence of anticoagulant, anuhaemolytic and arulthrombotic agents. The methods applied for isolation and other conditions during the isolation affect the yield or the compositions of the oil, for instance with steam distillation the allicin will decompose whereas extraction at room temperature will yield oil with allicin as the main component. In the present study isolation was conducted by extraction with ethylacetate or ethanol and the oil obtained was tested for their antibacterial capacity. Tests against Staphylococcus aureus, Bacillus cereus and Escherichia coli indicated that the isolated oil were active. On the other hand, commercial garlic extract (KGE) and garlic oil capsule (GOC) gave negative test. This may have been due to either insufficient concentration. of the biologically active component present in the commercial drugs or different method of extraction process. investigation with thin layer chromatography (TLC) of the drugs On silica gel plate ustngn-hexane and ethyl acetate as eluents showed six components in the GOC and none in KGE whereas for the isolated oil 13 components were identified with iodine vapour. Although the oils indicated antibacterial activity, it is somehow less active compared with oxytetracycline which is used as reference.
ANTICANCER ACTIVITIES OF SECONDARY METABOLITES PRODUCED BY TAXUS ENDOPHYTIC FUNGUS PHOMOPSIS CHIMONANTHI A. Desak Gede Sri; J. p. Raymond; Harmastmi Harmastini; L.B. S. Kardono,; M. Hanafi; E. Meiyanto
Jurnal Kimia Terapan Indonesia Vol 13, No 1 (2011)
Publisher : Research Center for Chemistry - LIPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3233.791 KB) | DOI: 10.14203/jkti.v13i1.125

Abstract

Secondary metabolite by the Taxus endophytic fungus strain Tse3 culture obtained from the West Java Forest has been produced. Production of secondary metabolite had done by aerobic fermentation for 7 days, 3(fC, 120 rpm in PDB (potato dextrose broth) media. The broth of fermentation was extracted by ethyl acetate. Various concentrations of the ethyl acetate extract in (0- 800) mcg/mL were prepared and test against T47D cancer cell line. Cytotoxic test has be done by MTTmethod. ICso value of ethyl acetate extract was 3 mcg/mL. The result of fungus identification by morphology and molecular 18S rRNA was Phomopsis chimonanthi.Key words: Phomopsis chimonanthi, fermentation, isolation, cytotoxicity, identification, taxus
ISOlASI DAN ELUSIDASI SENYAWA KIMIA DARI KULIT POHON Garcinia tetrandra PIERRE Soleh Kosela; leonardus B. Kardono; M. Hanafi
Jurnal Kimia Terapan Indonesia Vol 10, No 1-2 (2000)
Publisher : Research Center for Chemistry - LIPI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3414.945 KB) | DOI: 10.14203/jkti.v10i1-2.178

Abstract

A preliiminary study was carried out to isolate theconstituents of the stem bark of Garcinia tetran dra Pierre(Guttiferae). Several species of this family had been known asmedicinal herb, some other contain bioactive constituents andnovel compounds. The isolation were carried out by macerationin n-hexane where crude extract was purified usingchromatographic technique on SIG60 coloumn and n- hexane ethylacetate as eluents by gradient. Two pure compunds werefound and their molecular structures were determined on thebasis of combined spectroscopic methods UV, IR, 1H-NMR, l3C-NmR and MS and comparison with literature. The compouridhad been identified as xanton, 15-hydroxy-20, 21, 22, 23-tetramethyl-3H,11H-dipyrano (3, 2-a ; 2'. 3'-i) xanten-17-one(A), known as Thwaitesixanton and a triterpene as Hopenol - a(Hop-(22) (29)-en 3-0 ol) (B).
Co-Authors A. Desak Gede Sri A. T. Karossi E. Meiyanto Harmastmi Harmastini J. p. Raymond L. Sutedja L.B. S. Kardono, leonardus B. Kardono Soleh Kosela