Gustina Lubis
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Serum Zinc Level at Term Pregnancy and Newborn Anthropometry Seriana, Irma; Yusrawati, Yusrawati; Lubis, Gustina
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.719 KB) | DOI: 10.32771/inajog.v3i4.53

Abstract

Objective: To determine the relationship between serum zinc level at term pregnancy and newborn anthropometry. Methods: This study is an observational study with cross-sectional design. Serum zinc level at term pregnancy was measured and then anthropometric measurement was done to the newborn, including birth weight, birth length and head circumference at birth. The data were statistically analyzed using regression correlation test. Results: Mean serum zinc level at term pregnancy is 36.01 μg/dl (SD=18.34 μg/dl), the average birth weight is 3158 gr (SD=480.4 gr), the average birth length is 48.42 cm (SD=1.75 cm) and the average head circumference at birth is 33.13 cm (SD=1.14 cm). There was no statistically significant relationship between serum zinc levels at term pregnancy and birth weight (p-value=0.152). Meanwhile, there are statistically significant relationships between serum zinc level at term pregnancy with birth length and head circumference with pvalue 0.026 and 0.012, respectively. Conclusion: Serum zinc level at term pregnancy is correlated with birth length and head circumference, but is not correlated with birth weight. [Indones J Obstet Gynecol 2015; 3-4: 190-195] Keywords: birth length, birth weight, head circumference at birth, serum zinc level, term pregnancy
The Effect of Pediococcus pentosaceus on Stool Frequency, TNF-α Level, Gut Microflora Balance in Diarrhea-induced Mice Yuliawati, Yuliawati; Jurnalis, Yusri Dianne; Purwati, Endang; Lubis, Gustina
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 2, August 2012
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.24871/132201297-102

Abstract

Background: Enteropathogenic Escherichia coli (EPEC) are pathogenic microorganisms causing inflammation and imbalanced gut microflora that may result in diarrhea. Pediococcus pentosaceus (P. pentosaceus) isolated from “dadih” (milk curd) are used as probiotics containing lactic acid bacteria (LAB), which are useful to improve the balance of intestinal microflora and inhibit the growth of pathogenic microorganisms. This study was aimed to recognize the effect of P. pentosaceus supplementation on stool frequency, tumor necrosis factor-α (TNF-α) and gut microflora balance in experimental mice with EPEC-induced diarrhea. Method: The study was conducted in 60 white mice (Mus muscullus) at Biomedical Laboratory, Biotechnology/Production and Animal Husbandry Technology Institute, University of Andalas, Padang in April 2012. The frequency of stool, TNF-α level and microflora balance of the mice were measured before and after the EPEC-induced diarrhea and following the administration of antibiotics. Statistical analysis was performed using ANOVA and Duncan test. Results: The highest mean stool frequency was found in positive control group, i.e. 55 times, which was reduced significantly after 12-hour P. pentosaceus supplementation in a dose of 2 x 108 cfu/g into 18 times. The mean TNF-α level in positive control group was 128.17 pg/mL that lowered significantly to 48.0 pg/mL. The highest mean total number of LAB was 97.0 x 107 cfu/g, which was significantly different from positive control group of 7 x 107 cfu/g. Conclusion: P. pentosaceus supplementation in a dose of 2 x 108 cfu/g may reduce the stool frequency, lower TNF-α and improve the gut microflora balance following 12-hour supplementation in diarrhea-induced mice. Keywords: Pediococcus pentosaceus, TNF-α, diarrhea, EPEC, gut microflora
Serum Zinc Level at Term Pregnancy and Newborn Anthropometry Seriana, Irma; Yusrawati, Yusrawati; Lubis, Gustina
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.719 KB) | DOI: 10.32771/inajog.v3i4.53

Abstract

Objective: To determine the relationship between serum zinc level at term pregnancy and newborn anthropometry. Methods: This study is an observational study with cross-sectional design. Serum zinc level at term pregnancy was measured and then anthropometric measurement was done to the newborn, including birth weight, birth length and head circumference at birth. The data were statistically analyzed using regression correlation test. Results: Mean serum zinc level at term pregnancy is 36.01 μg/dl (SD=18.34 μg/dl), the average birth weight is 3158 gr (SD=480.4 gr), the average birth length is 48.42 cm (SD=1.75 cm) and the average head circumference at birth is 33.13 cm (SD=1.14 cm). There was no statistically significant relationship between serum zinc levels at term pregnancy and birth weight (p-value=0.152). Meanwhile, there are statistically significant relationships between serum zinc level at term pregnancy with birth length and head circumference with pvalue 0.026 and 0.012, respectively. Conclusion: Serum zinc level at term pregnancy is correlated with birth length and head circumference, but is not correlated with birth weight. [Indones J Obstet Gynecol 2015; 3-4: 190-195] Keywords: birth length, birth weight, head circumference at birth, serum zinc level, term pregnancy
Hubungan Pola Makan dengan Status Gizi Anak Usia 3-5 tahun di Wilayah Kerja Puskesmas Nanggalo Padang 2014 Gustiva Sari; Gustina Lubis; Edison Edison
Jurnal Kesehatan Andalas Vol 5, No 2 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i2.528

Abstract

AbstrakStatus gizi yang buruk merupakan salah satu penyebab kematian pada anak. Jumlah anak dengan status gizi kurang dari tahun 2011 ke tahun 2012 di wilayah kerja Puskesmas Nanggalo mengalami peningkatan. Tujuan penelitian ini adalah menentukan hubungan pola makan dengan status gizi pada anak usia 3-5 tahun di wilayah kerja Puskesmas Nanggalo. Desain penelitian ini adalah cross sectional study dengan pola makan sebagai variabel independen dan status gizi sebagai variabel dependen. Populasi penelitian ini adalah semua anak usia 3-5 tahun yang berdomisili di wilayah kerja Puskesmas Nanggalo. Pengambilan subjek menggunakan teknik simple random sampling yang dibuat secara proporsional. Analisis data menggunakan uji Fisher. Hasil penelitian yang didapatkan 68% anak dengan pola makan yang baik mempunyai status gizi normal, dan 11% anak dengan pola makan tidak baik mengalami kekurusan. Hasil uji statistik menunjukkan pola makan mempunyai hubungan dengan status gizi (p=0,000). Dapat disimpulkan bahwa terdapat hubungan yang antara pola makan dengan status gizi. Penerapan pola makan yang baik pada anak maka status gizi anak akan menjadi baik.Kata kunci: pola makan, status gizi, anak usia 3-5 tahun AbstractMalnutrition is one of the cause of childhood deaths. The year of 2011 until 2012, the cases of children with malnutrition in area of Nanggalo Health Center was increased. The objective of this study was to determine the correlation  diet on nutritional status in children aged 3-5 years old in area of Nanggalo Health Center. This research used cross-sectional study, the diet as the independent variable and nutritional status as the dependent variable. The population was all of children aged 3-5 years in area of Nanggalo Health Center. Subjects was taken by using simple random sampling technique with proportionally. The data analysis was Fisher test. The results of the study found 68% of children with a good diet have normal nutritional status, and 11% of children with a bad diet have a stunting. The Statistic results showed that diet has a relationship on nutritional status (p = 0.000). Keywords: diet, nutritional status, children aged 3-5 year old
Hubungan Pemberian Makanan Pendamping Asi (MP-ASI) dengan Status Gizi Anak Usia 1-3 Tahun di Kota Padang Tahun 2012 Mahaputri Ulva Lestari; Gustina Lubis; Dian Pertiwi
Jurnal Kesehatan Andalas Vol 3, No 2 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i2.83

Abstract

AbstrakMakanan pendamping ASI (MP-ASI) adalah makanan padat yang mengandung nutrien lengkap yang diberikan kepada bayi mulai usia 6 bulan disamping ASI eksklusif untuk mencapai tumbuh kembang yang optimal. Tujuan penelitian adalah untuk mengetahui hubungan antara usia pemberian MP-ASI dan jenis MP-ASI dengan status gizi. Penelitian ini merupakan studi cross sectional yang dilaksanakan pada bulan Mei-November 2012 pada anak usia 1-3 tahun yang berdomisili di Kota Padang. Pengumpulan data karakteristik responden, usia pemberian MP-ASI, dan jenis MP-ASI dilakukan dengan wawancara terpimpin. Pengukuran status gizi dilakukan berdasarkan BB/TB Z-score. Analisis statistik yang digunakan adalah uji chi square. Hasil penelitian menunjukan dari 200 anak, 51% anak diberi diberi MP-ASI sesuai jadwal dengan jenis MP-ASI buatan pabrik. Status gizi kurang, lebih banyak didapatkan pada anak yang diberi MP-ASI dini (33%). Tidak ditemukan anak dengan status gizi buruk.Terdapat hubungan antara usia pemberian MP-ASI dengan status gizi p= 0,001 (P < 0,05) dan tidak ada hubungan antara jenis MP-ASI dengan status gizi p= 0,456 (p > 0,05).Kata kunci: MP-ASI, Status gizi, Anak usia 1-3 tahunAbstractComplementary feeding is a solid and nutrient dense foods that contain complete given to infants from 6 months of age are exclusively breastfed in addition to achieve optimal growth and development. The research objective was to determine the relationship between the age of complementary feeding and provision of complementary feeding types with nutritional status. This study is a cross-sectional study that was conducted in May-November 2012 on children aged 1-3 years who live in Padang. The characteristics of the respondents, aged giving complementary feeding, and the type of complementary feeding by the guided interview. Measurement of nutritional status is based on weight / height Z-score.The statistical analysis used was chi square test. The results showed that of 200 children, 51% children were given complementary feeding schedule. The type was given is complementary feeding of factory. Nutritional status is much less than was found in children who were given complementary feeding early (33%). There are no children with poor nutritional status. There is a significant association between age of Complementary feeding with nutritional status p = 0.001 (P < 0.05) and there was no significant association between the type of Complementary feeding with nutritional status p = 0.456 (p >0.05).Keywords:Complementary feeding, nutritional status, children aged 1-3 years
Hubungan Pemberian ASI Eksklusif dengan Angka Kejadian Diare Akut pada Bayi Usia 0-1 Tahun di Puskesmas Kuranji Kota Padang Eka Putri Rahmadhani; Gustina Lubis; Edison Edison
Jurnal Kesehatan Andalas Vol 2, No 2 (2013)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v2i2.120

Abstract

AbstrakPemberian ASI eksklusif merupakan salah satu upaya untuk mencapai tumbuh kembang optimal dan terlindungi dari penyakit seperti diare. Tujuan penelitian ini adalah untuk mengetahui hubungan pemberian ASI eksklusif dengan angka kejadian diare akut pada bayi usia 0-1 tahun di Puskesmas Kuranji Kota Padang. Penelitian ini dilaksanakan secara observasional dengan pendekatan cross sectional. Sampel penelitian ini adalah bayi usia 0-1 tahun yang berkunjung ke posyandu di wilayah kerja Puskesmas Kuranji Kota Padang dengan menggunakan simple random sampling. Jumlah bayi dengan kelompok usia 0-5 bulan 29 hari sebanyak 69 orang (51,1%) dan usia 6-12 bulan sebanyak 66 orang (48,9%). Dari hasil penelitian didapatkan bayi usia 0-5 bulan 29 hari yang masih mendapat ASI saja sebanyak 41 bayi (30,4%) dan yang sudah mendapat campuran lain selain ASI sebanyak 28 bayi (20,7%). Jumlah bayi usia 6-12 bulan dengan ASI eksklusif sebanyak 34 bayi (25,2%) dan 32 bayi lainnya (23,7%) non ASI eksklusif. Sebanyak 57 bayi (42,2%) pernah diare dan 78 bayi lainnya (57,8%) tidak pernah. Analisis chi square mendapatkan p=0,001 dan hasil ini signifikan (p<0,5). Pemberian ASI eksklusif selama 6 bulan harus ditingkatkan karena mempunyai hubungan dengan angka kejadian diare akut.Kata kunci: Bayi, ASI Exclusif, diareAbstractExclusive breastfeeding is an effort to achieve optimal growth and development and can be protected from diarrhea. The purpose of this study was to determine the relationship of exclusive breastfeeding with the incidence of acute diarrhea in infants aged 0-1 years in the Kuranji Public Health Center Padang. This study conducted a cross sectional observational study. The sample was a baby aged 0-1 years who visited posyandu in the Kuranji Public Health Center working area using simple random sampling. The result showed 41 infants (30.4%) aged 0-5 months 29 days which is still breastfed only and other than breast milk were 28 infants (20.7%). Number of 6-12 months infants are exclusively breastfed as many as 34 babies (25.2%) while the other 32 babies (23.7%) were not exclusively breastfed. A total of 57 infants (42.2%) had suffered from diarrhea and the other 78 infants (57.8%) had never. Chi square analysis got p = 0.001 and the results are significant (p <0.5). Exclusive breastfeeding for 6 months should be improved because it has relation with diarrhea.Keywords:Baby, Exclusive breastfeeding, diarrhea
Pengaruh Pemberian Amylase Resistant Starch Terhadap Durasi Diare dan Kadar Secretory Immunoglobulin A pada Anak dengan Diare Akut Trisna Resti Yanti; Yusri Dianne Jurnalis; Fadil Oenzil; Gustina Lubis
Sari Pediatri Vol 19, No 4 (2017)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (100.628 KB) | DOI: 10.14238/sp19.4.2017.226-30

Abstract

Latar belakang. Cairan rehidrasi oral (CRO) merupakan terapi utama dalam tata laksana diare. Berbagai upaya dilakukan untuk penyempurnaan CRO agar menjadi lebih efektif dengan penambahan probiotik, prebiotik, zink, dan protein polimer. Amylase resistant starch adalah polisakarida yang tidak dapat dihidrolisis oleh enzim α-amilase dan berperan sebagai prebiotik. Tujuan. Mengetahui pengaruh pemberian amylase resistant starch terhadap durasi diare dan kadar secretory immunoglobulin A (sIgA) pada anak dengan diare akut Metode. Studi eksperimental tidak tersamar pre and post-test group design dilakukan pada 24 anak diare akut dehidrasi sedang berumur 6 - 60 bulan yang dirawat di RSUP dr. M. Djamil dan RSUD Rasidin Padang pada bulan Maret 2016 - Juni 2017. Subjek dibagi dalam 2 kelompok, yaitu kelompok kontrol dan intervensi yang diberikan amylase resistant starch. Uji statistik digunakan t test dan Mann-Whitney test.Hasil. Kelompok intervensi memiliki durasi diare yang lebih pendek (72,67±19,04) jam dibandingkan dengan kontrol (85,08±11,05) jam. Perubahan kadar sIgA lebih tinggi pada kelompok intervensi (8,13 ng/ml) dibandingkan dengan kelompok kontrol (4,27 ng/ml).Kesimpulan. Pemberian amylase resistant starch pada anak dengan diare akut akan memperpendek durasi diare meningkatan kadar secretory immunoglobulin A. 
Perbedaan Kadar Lisozim dalam Air Susu Ibu (ASI) pada Bayi Sehat dan Bayi Sakit yang Mendapat ASI Eksklusif Irwandi Irwandi; Gustina Lubis; Nur Indrawati Lipoeto
Sari Pediatri Vol 19, No 5 (2018)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp19.5.2018.273-8

Abstract

Latar belakang. Air susu ibu (ASI) sangat diperlukan selama masa pertumbuhan dan perkembangan bayi untuk meningkatkan daya tahan tubuh karena mengandung anti mikroba seperti lisozim. Air Susu Ibu mengandung 300 kali lebih banyak lisozim dibandingkan susu sapi. Lisozim berperan sebagai sistem imunitas alami yang dapat melindungi bayi dari berbagai macam infeksi.Tujuan. Mengetahui perbedaan kadar lisozim dalam ASI pada bayi sehat dan bayi sakit yang mendapat ASI eksklusif.Metode. Penelitian ini menggunakan desain potong lintang komparatif, dilakukan pada September-November 2016 di beberapa Puskesmas di kota Padang dan RSUP Dr M Djamil Padang.Hasil. Lisozim lebih tinggi dalam ASI di kelompok bayi sakit dibandingkan ASI di kelompok bayi sehat, tetapi perbedaannya tidak bermakna (p 0,183). Lisozim lebih tinggi dalam ASI di kelompok bayi yang menderita infeksi saluran nafas dibandingkan dengan bayi yang menderita infeksi saluran cerna. Kesimpulan. Terdapat perbedaan kadar lisozim dalam ASI pada bayi sehat dan bayi sakit yang mendapat ASI eksklusif, tetapi secara statistik perbedaannya tidak bermakna.
Relationship between serum ferritin and zinc levels in patients with major thalassemia Hervita Yeni; Finny Fitry Yani; Amirah Zatil Izzah; Gustina Lubis
Paediatrica Indonesiana Vol 59 No 3 (2019): May 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.731 KB) | DOI: 10.14238/pi59.3.2019.144-9

Abstract

Background In thalassemia patients, reduced zinc absorption results from increased serum iron due to repeated blood transfusions, increased iron absorption due to ineffective erythropoiesis, and competitive inhibition between iron and zinc in binding to transferrin, a means of transporting both types of minerals in the blood. Few studies have been done to examine zinc levels in thalassemia patients and its relationship with ferritin. Objective To compare serum zinc in thalassemia patients and healthy controls and to assess for a possible correlation between serum ferritin and zinc in thalassemia patients. Methods This cross-sectional study in 68 subjects was done from October 2016 to August 2017. Serum ferritin measured by chemiluminescence immunoassay and serum zinc by inductively coupled plasma mass spectrometry (ICP-MS). Wilcoxon test was used to analyze for differences between serum zinc in thalassemia patients and controls. Spearman’s correlation test was used to analyze for a possible correlation between ferritin and serum zinc in thalassemia patients. Results There were 34 patients with thalassemia and 34 healthy control subjects. The median serum zinc was 119.34 µg/dL (IQR=71.27) in the thalassemia group and 120.08 µg/dL (IQR=26.28) in the control group (P=0.36). There was no significant correlation between serum ferritin and zinc in thalassemic children (r=-0.023; P=0.895). Conclusion There is no significant difference in serum zinc levels between thalassemic children and healthy controls. There is no significant correlation between serum ferritin and zinc in thalassemic children.
The Effect of Pediococcus pentosaceus on Stool Frequency, TNF-α Level, Gut Microflora Balance in Diarrhea-induced Mice Yuliawati Yuliawati; Yusri Dianne Jurnalis; Endang Purwati; Gustina Lubis
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 2, August 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (717.058 KB) | DOI: 10.24871/132201297-102

Abstract

Background: Enteropathogenic Escherichia coli (EPEC) are pathogenic microorganisms causing inflammation and imbalanced gut microflora that may result in diarrhea. Pediococcus pentosaceus (P. pentosaceus) isolated from “dadih” (milk curd) are used as probiotics containing lactic acid bacteria (LAB), which are useful to improve the balance of intestinal microflora and inhibit the growth of pathogenic microorganisms. This study was aimed to recognize the effect of P. pentosaceus supplementation on stool frequency, tumor necrosis factor-α (TNF-α) and gut microflora balance in experimental mice with EPEC-induced diarrhea. Method: The study was conducted in 60 white mice (Mus muscullus) at Biomedical Laboratory, Biotechnology/Production and Animal Husbandry Technology Institute, University of Andalas, Padang in April 2012. The frequency of stool, TNF-α level and microflora balance of the mice were measured before and after the EPEC-induced diarrhea and following the administration of antibiotics. Statistical analysis was performed using ANOVA and Duncan test. Results: The highest mean stool frequency was found in positive control group, i.e. 55 times, which was reduced significantly after 12-hour P. pentosaceus supplementation in a dose of 2 x 108 cfu/g into 18 times. The mean TNF-α level in positive control group was 128.17 pg/mL that lowered significantly to 48.0 pg/mL. The highest mean total number of LAB was 97.0 x 107 cfu/g, which was significantly different from positive control group of 7 x 107 cfu/g. Conclusion: P. pentosaceus supplementation in a dose of 2 x 108 cfu/g may reduce the stool frequency, lower TNF-α and improve the gut microflora balance following 12-hour supplementation in diarrhea-induced mice. Keywords: Pediococcus pentosaceus, TNF-α, diarrhea, EPEC, gut microflora