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CATHETER DURATION AND THE RISK OF SEPSIS IN PREMATURE BABIES WITH UMBILICAL VEIN CATHETERS Hartojo, Hartojo; Utomo, Martono Tri
Indonesian Journal of Tropical and Infectious Disease Vol 3, No 1 (2012)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.254 KB)

Abstract

Umbilical catheters are frequently required in the management of severely ill premature babies. The risk of complications may increase with duration of UVC use. Objective: To determine whether the risk of central line-associated bloodstream infections (CLA-BSIs) and sepsis remained constant over the duration of umbilical vein catheters (UVCs) in high-risk premature neonates.Methods:retrospective analysis. The data were collected from the medical record of high risk premature neonates who had a UVC placed in neonatal care unit of Husada Utama Hospital between April 1st 2008 to April 30th 2011 with purposive sampling. Catheter duration was observed before and after 14 days on placement. Blood and UVC culture was performed to establish the risk of CLA-BSIs and sepsis. Chi-square and logistic regression analysis were performed in the laboratorium data. Result: A total 44 high risk premature babies with UVCs were enrolled (sepsis group: n = 23 and non sepsis group: n = 21). Baseline demographics were similar between the groups. 15 babies in sepsis group have UVCs duration > 14 days, and 8 babies have UVCs < 14 days (p = 0.533). Days of UVC < 14 days show UVCs culture performance in 11 babies with positive evidence, blood culture performance shows negative in 21 babies (p = 0.516). Days of UVC >14 days show blood culture performance in 11 babies with positive evidence, UVCs culture performance is negative in 18 babies (p = 0.456). Burkholderia cepacia and Klebsiella pneumonia mostly appeared in blood culture performance. 25% of UVC culture performance shows Pseudomonas aeroginosa. Conclusions: The catheter duration have no significant differencein risk of sepsis in premature babies with Umbilical Vein Catheters.
DETERMINAN “PICKY EATER” (PILIH-PILIH MAKANAN) PADA ANAK USIA 1- 3 TAHUN (Studi di Wilayah Kerja Puskesmas Jabon Sidoarjo) Kusumawardhani, Niken; Rachmat Hargono, Windhu Purnomo; Martono Tri Utomo Sri Andari, Siti Nurul Hidayat
HOSPITAL MAJAPAHIT (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT) Vol 5, No 2 (2013): HOSPITAL MAJAPAHIT VOL 5 NO 2
Publisher : HOSPITAL MAJAPAHIT (JURNAL ILMIAH KESEHATAN POLITEKNIK KESEHATAN MAJAPAHIT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.10475/hm.v5i2.459

Abstract

Picky eater is one of the important issues in child growth that have to be concerned by parents and health practitioners, due to the negative effect of imbalance increasing of weight, important nutrition defeciency, also lack of variation of food consumptions. If this issue does not immediately treated it can cause a long term effect of an unhealthy or slow development and growth in children. Sample of population used in this research are all children aged 1-3 years old in Posyandu of Puskesmas Jabon in March until May 2013. The type of this study was an analytic with case control design study. The total of sample was 106 children devided in case (n=53) and control groups (n=53) and using Multiple Logistic Regression Test. The outcome of this research are showing all illness that have been suffered by all children in last 3 months, lack of interaction between mother and children, parents selective food behavior, not given enough exclusive breastfed for 6 months, given weaning food less than or more than 6 months, children is raised by people other than parents, socio-cultural dietetic view, unmatching frequencies between consumption and age, improper mealtimes, and improper feeding techniques are all crucial in affeting selective eating disorder in children aged 1-3 years in area of work of Puskesmas Jabon Sidoarjo in 2013.Key words: Picky eater disorder
ANALISIS FAKTOR RISIKO DAN LUARAN DARI PENGGUNAAN TERAPI ANTIBIOTIK EMPIRIK JANGKA PANJANG PADA BAYI DENGAN BERAT LAHIR SANGAT RENDAH DALAM KONDISI SEPSIS Reza, Muhammad; Sampurna, Mahendra Tri Arif; Handayani, Kartika Darma; Angelika, Dina; Utomo, Martono Tri; Etika, Risa; Harianto, Agus
Majalah Kesehatan FKUB Vol 6, No 4 (2019): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (682.154 KB) | DOI: 10.21776/ub.majalahkesehatan.2019.006.04.4

Abstract

Terapi antibiotik berkepanjangan pada neonatus menyebabkan beberapa konsekuensi negatif meliputi resistensi antibiotik, sepsis awitan lambat, enterocolitis nekrotikan (EKN), lama rawat lebih panjang, dan peningkatan mortalitas. Semua faktor tersebut mempengaruhi efisiensi biaya pelayanan rumah sakit di era Jaminan Kesehatan Nasional. Penelitian ini bertujuan untuk menganalisis faktor risiko dan luaran dari terapi antibiotik berkepanjangan pada bayi berat lahir sangat rendah (BBLSR) dengan sepsis. Desain penelitian adalah studi retrospektif pada BBLSR dengan sepsis di Neonatal Intensive Care Unit (NICU), RSUD Dr. Soetomo, Surabaya sejak Januari-Desember 2017 dilakukan dengan membandingkan luaran antara kelompok I yang mendapat terapi antibiotik empirik kurang dari sama dengan 2 minggu dengan kelompok II yang mendapat terapi antibiotik empirik lebih dari 2 minggu empirik. Dari 87 bayi yang termasuk ke dalam studi, 37 bayi termasuk dalam kelompok I dan 50 bayi dalam kelompok II. Rerata durasi terapi antibiotik pada kelompok I dan kelompok II adalah 9,2±2,5 dan 17,9±3,2 hari, dengan lama rawat inap 19,7±8,5 dan 27,2±13,1 hari. Analisis faktor risiko menunjukkan bahwa BBLSR terutama 1000 gram (p < 0,001), ventilasi mekanik invasif (p < 0,001), ventilasi mekanik non-invasif (p < 0,001), korioamnionitis (p = 0,003), penyakit maternal (p = 0,004), kehamilan multipel (p = 0,03) merupakan faktor risiko mendapatkan terapi antibiotik empirik berkepanjangan. Luaran dari terapi antibiotik empirik berkepanjangan adalah 41 (47%) bayi mengalami sepsis awitan lambat,  15 (17%) bayi dengan EKN, dan 11 (12%) bayi meninggal. Mortalitas bayi dengan sepsis awitan lambat (p < 0,001) dan EKN (p = 0,02) lebih tinggi pada kelompok II dibandingkan kelompok I. Kesimpulannya, terapi antibiotik empirik berkepanjangan meningkatkan angka kejadian sepsis awitan lambat, enterocolitis nekrotikan, lama rawat, dan mortalitas BBLSR di NICU yang berdampak meningkatkan biaya pelayanan rumah sakit.  
Risk Factors of Rebound Hyperbilirubinemia in Post Phototherapy Hyperbilirubinemia Infants Alexander Leonard Caesar Josediputra; Martono Tri Utomo; Risa Etika
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16774

Abstract

Background: Post phototherapy rebound hyperbilirubinemia is a cause for readmission in some infants.However, this phenomenon data of rebound hyperbilirubinemia is lacking from Indonesia. Our study aimsto describe the risk factor of post phototherapy rebound hyperbilirubinemia in the infant.Method: Cross-sectional study of all infants with indirect hyperbilirubinemia who were treated phototherapyaccording to standard guidelines in neonate intermediate unit Dr. Soetomo hospital for 6 months from June2017 until December 2017. Bilirubin was measured 24 hours after phototherapy. Bilirubin rebound isconsidered as increasing total serum bilirubin that needs reinstitution of phototherapy.Result: A total of 53 (44.9%) infants developed rebound hyperbilirubinemia. We revealed the following riskfactor for rebound hyperbilirubinemia was the onset of jaundice on < 3 days, (10 babies, p <0.05). Otherresults are 30 (56.6%) female infants, 39 (73%) birth weight < 2500 g, 36 (67%) infants with a history ofcesarean section, and 38 (71%) preterm infants but there are not statistically significant.Conclusion: Post phototherapy rebound hyperbilirubinemia should be considered in the onset of jaundice< 3 days.
Galactooligosaccharide (GOS) Fortified Formula Feeding in Premature Infants Martono Tri Utomo; Muhammad Reza; Risa Etika; Talitha Y. Aden; Iwan S. Handoko; Ruth A. Alexander
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17587

Abstract

Background: Nutritional problems are one of the serious problems in low birth weight or preterm infants. This causes medical and nutrition management of premature infants to be more individual. Objective: To evaluate the outcome of the premature infants with Galactooligosaccharides (GOS) fortified formula feedingMethods: This was prospective, open label cohort study that conducted during March- December 2019 in Neonatology Unit at the one of the main referral hospitals in East Java, Indonesia. The population of the study was very low birth weight infants (1,000 g - ≤1,500g) who needed formula feeding. Weight, body length, head circumference, fecal models and the incidence of diarrhea, colic, regurgitation, and vomiting was observed. Patients were observed for 28 days or adjusted according to length of stay.Results: Totally, 20 infants were included. Mean birth weight was 1236.2±148.5 grams. Mean total volume Galactooligosaccharides fortified formula at the start of recruitment was 209.4±46.1 ml and at the end of observation was 267.9±41.2 ml. There were change in amount and consistency of feces before and after intervention. No patient experienced adverse events (diarrhea, colic, regurgitation or vomiting) while consuming Galactooligosaccharides fortified formula. Conclusion: Galactooligosaccharides fortified formula in premature infant formula did not have a detrimental effect on premature infants and did not cause intolerance
Echocardiographic Study in Preterm Infant with Hemodynamic Significant Patent Ductus Arteriosus Sunny Mariana Samosir; Martono Tri Utomo; Mahrus A. Rahman; Risa Etika; Dina Angelika; Kartika Darma Handayani; Agus Harianto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17650

Abstract

Background: Potential complications of hemodynamic significant patent ductus arteriosus (hsPDA) after birth include heart failure, need for respiratory support, renal disfunction, intraventricular hemorrhage, as well as long term altered growth and development. Nevertheless, clinical signs of patent ductus arteriosus (PDA) are not sensitive and specific enough. Therefore, echocardiography still remains the preferred method to evaluate the ductal patency in preterm infant. The present study aimed to evaluate the echocardiography characteristic in preterm infant with hsPDA.Methods: A cross-sectional study was conducted on preterm infants aged 3-7 days with 24-336/7 weeks of gestation. Data taken were demographic, clinical and echocardiography. Diagnosis of hsPDA was carried out by echocardiography; defined as >1.5mm diameter of ductus and >1.4 left pulmonal artery and aorta (La/Ao) ratio. The statistical analysis was undertaken using SPSS 21.0.Results: There were 11 out of 52 preterm infants diagnosed hsPDA. Mean birth weight was 1213±293 gram; Mean gestational age was 30.72±2.01 weeks. In hsPDA group, mean ductus diameter was 2.84±0.93 mm, mean La/Ao ratio was 1.56±0.26, and mean ejection fraction (EF) was 71.55±5.72%.Conclusion: Echocardiographic evaluation is important for addressing hsPDA in preterm infants.
THE CORRELATION BETWEEN APGAR SCORE AND GESTATIONAL AGE WITH NEONATAL SEPSIS AND ASSOCIATED MORTALITY Nabila Annisa Harum; Martono Tri Utomo; Aditiawarman -; Prastiya Indra Gunawan
JURNAL WIDYA MEDIKA Vol 7, No 2 (2021): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v7i2.3388

Abstract

Background: Neonatal sepsis is increasingly recognized as an important global health problem that challenges neonatal survival. In 2018, sepsis caused approximately 15% of all neonatal deaths worldwide. Recent data regarding preterm birth and low Apgar score as risk factors for neonatal sepsis-related death have not been reported in Indonesia. Methods: This was a case-control study conducted in Dr.Soetomo General Hospital. A case group was obtained from medical records by a total sampling of all neonates diagnosed with neonatal sepsis in 2019, and a control group of non-neonatal sepsis cases was taken by random sampling. Chi-square test and logistic regression were used to analyze the data. Results: Statistical analysis showed a significant correlation between one and five-minute Apgar score
Ence Of ESBL Bacteria In Baby Box Handle At Dr. Soetomo Hospital Manik Retno Wahyunitisari; Martono Tri Utomo; Nicholas Fernando Purnomo
JURNAL WIDYA MEDIKA Vol 6, No 2 (2020): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v6i2.2789

Abstract

Health Associated Infection (HAI) in neonates can increase neonatal infection risk, which is a fairly frequent cause of neonatal death. Microorganisms that are quite often found to contaminate include gram-negative bacteria such as Escherichia coli and Klebsiella pneumoniae. Gram-negative bacteria are also quite often found to have resistance to antibiotic therapy that is usually given, especially actlactam, and will increase the degree of disease to mortality, this bacterium is called ESBL. The study was conducted to determine the level of ESBL bacterial contamination in health facilities at Dr. Soetomo general hospital. Swabs are taken and biochemical tests were done to identify pathogen species. These isolates were also tested for ESBL production by the double-disc synergy test (DDST). There were 30 samples that contaminate the handle of the baby box, 2 of which (6.67%) tested positive for ESBL. With good hand hygiene, the use of disinfectants in medical devices, floors, walls, and doors, maintenance and replacement of tap water filters, and regular monitoring can reduce the number of bacterial contamination.
CATHETER DURATION AND THE RISK OF SEPSIS IN PREMATURE BABIES WITH UMBILICAL VEIN CATHETERS Hartojo Hartojo; Martono Tri Utomo
Indonesian Journal of Tropical and Infectious Disease Vol. 3 No. 1 (2012)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.254 KB) | DOI: 10.20473/ijtid.v3i1.194

Abstract

Umbilical catheters are frequently required in the management of severely ill premature babies. The risk of complications may increase with duration of UVC use. Objective: To determine whether the risk of central line-associated bloodstream infections (CLA-BSIs) and sepsis remained constant over the duration of umbilical vein catheters (UVCs) in high-risk premature neonates.Methods:retrospective analysis. The data were collected from the medical record of high risk premature neonates who had a UVC placed in neonatal care unit of Husada Utama Hospital between April 1st 2008 to April 30th 2011 with purposive sampling. Catheter duration was observed before and after 14 days on placement. Blood and UVC culture was performed to establish the risk of CLA-BSIs and sepsis. Chi-square and logistic regression analysis were performed in the laboratorium data. Result: A total 44 high risk premature babies with UVCs were enrolled (sepsis group: n = 23 and non sepsis group: n = 21). Baseline demographics were similar between the groups. 15 babies in sepsis group have UVCs duration > 14 days, and 8 babies have UVCs < 14 days (p = 0.533). Days of UVC < 14 days show UVCs culture performance in 11 babies with positive evidence, blood culture performance shows negative in 21 babies (p = 0.516). Days of UVC >14 days show blood culture performance in 11 babies with positive evidence, UVCs culture performance is negative in 18 babies (p = 0.456). Burkholderia cepacia and Klebsiella pneumonia mostly appeared in blood culture performance. 25% of UVC culture performance shows Pseudomonas aeroginosa. Conclusions: The catheter duration have no significant differencein risk of sepsis in premature babies with Umbilical Vein Catheters.
Neonatal Sepsis in Low Birth Weight Infants in Dr. Soetomo General Hospital Martono Tri Utomo
Indonesian Journal of Tropical and Infectious Disease Vol. 1 No. 2 (2010)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.539 KB) | DOI: 10.20473/ijtid.v1i2.2172

Abstract

Infections of the newborn are a significant cause of mortality. Preterm infant have a high risk sepsis.. The incidence of neonatal  sepsis is 1 to 10 cases per 1000 live births and 1 per 250 live premature births. To describe the characteristics of neonatal sepsis in the low birth weight infant in the neonatal intensive care unit Dr. Soetomo Hospital. Retrospective analysis. The data were collected from the medical record of low birth weight infants who were diagnosed as sepsis in neonatal care unit of Dr. Soetomo Hospital between January 2010 to June 2010 with purposive sampling. Descriptive analysis of risk factor of sepsis and blood culture of the patient was calculated. Chi-square analysis was performed in the laboratorium data. Characteristics sample: male vs female 61% vs 39%, outcome of sepsis in LBW was death 69%, alive 25%, risk of infection: turbid amniotic fluid 21%, asphyxia 33%. Laboratorium data leucopenia and thrombocytopenia (P < 0.05). Blood culture: Klebsiella pnemoniae. The incidence and mortality of neonatal sepsis in LBW infants was still high. Asphyxia, turbid amniotic fluid, leucopenia and thrombocytopenia were associated with sepsis. pneumoniae was the most common organisms in the LBW sepsis infants.