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All Journal Majalah Obstetri dan Ginekologi
Indwiani Astuti
Department of Pharmacotherapy, Molecular Biology, Faculty of Medicine Gadjah Mada University
Health Professions Medicine & Pharmacology

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Higher IL-1beta level in the follicular liquid of endometriosis compared with non-endometriosis patients Cahyono Hadi; Djaswadi Dasuki; Ahmad Hamim Sadewa; Indwiani Astuti; Awal Prasetyo
Majalah Obstetri dan Ginekologi Vol. 28 No. 2 (2020): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V28I22020.59-66

Abstract

Objective: To ascertain the IL-1b level in the follicular liquid of endometriosis sufferers compared with that of non-endometriosis sufferers.Materials and Methods: The ELISA method, for detecting the IL-1b, is taken from follicular fluid of endometriosis as well as non-endometriosis patients that diagnosed according to the ASRM criteria.Results: The 54 subjects were dominantly endometriosis <34 year old (88.9%).  The IL-1b levels of endometriosis patients and non-endometriosis patients were 82.86 ± 30.15 and 56.05 ± 23.27 respectively (p=0.01). The ROC value of IL-1b was found at a cut-off point of 26 (with the IL-1b cut-off point of 65.16). The discriminating value of AUC (area under curve) was 59.3%.Conclusion: It was concluded that the IL-1b level in endometriosis is higher than that in non- endometriosis.
Co-Authors Ahmad Hamim Sadewa Awal Prasetyo Cahyono Hadi Djaswadi Dasuki