Article Per Year (5 Year)
p-Index From 2018 - 2023
0.23
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Sriwijaya
Keisha Devita Primananda
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
C-KIT EXPRESSION IN VARIOUS DEGREES OF HISTOPATHOLOGY DIFFERENTIATION OF RETINOBLASTOMA IN MOHAMMAD HOESIN HOSPITAL PALEMBANG Rusdianto Rusdianto; Keisha Devita Primananda
Majalah Kedokteran Sriwijaya Vol 52, No 2 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i2.11978

Abstract

Retinoblastoma is a malignant intraocular neoplasm in pediatric which composed of embyonic tumour cells from retinoblasts of neuroepithelial origin with a relative incidence of 3% of all pediatric tumours. Histopathology examination can confirmed the diagnosis of retinoblastoma. Immunohistochemical staining with C-kit antibody can be used to identify the expression of C-kit in paraffin block of retinoblastoma sample.This study was conducted to identify C-kit expresion in various degrees of histopathology differentiation’s retinoblastoma in Mohammad Hoesin Hospital Palembang.. A descriptive study used on the paraffin blocks of 19 cases retinoblastoma in RSUP dr. Mohammad Hoesin from January 2012- July 2017. The degree of histopathologic differentiation and invasion of retinoblastoma was investigated by Hematoksilin-Eosin stain, and the C-kit expression stained by immunohistochemistry using antibody C-kit ready to use. Data was being presented in tabular form to identify C-kit expression. Retinoblastoma which expressed C-kit in this study are 63,16% among all sample. C-kit expressions were detected in 25% well differentiated, 50 % moderately differentiated, and 25% poorly differentiated of histopathological differentiation degree, also in 50% sample with optic nerve invasion and 58,33% in scleral invasion. C-kit expression was negative in 36,84% sample. In this study, C-kit expression was found more than half in retinoblastoma sample.
Co-Authors Rusdianto Rusdianto