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All Journal Nusantara Medical Science Journal Paediatrica Indonesiana International Journal of Health Science & Medical Research IJRETINA - International Journal of Retina
Ema Alasiry
Department Of Pediatric, Faculty Of Medicine, Hasanuddin University
Dentistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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THE ROLE OF HYPERLACTATEMIA STATUS AS A PROGNOSTIC PARAMETER IN CRITICALLY ILL NENONATES A Dwi Bahagia; Ema Alasiry; Djauharia A.M; Hanna Kurniawati
Nusantara Medical Science Journal Volume I No. 1 Januari-Maret 2016
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v0i1.2206

Abstract

ABSTRACT   Introduction:  Hypoxia and hypoperfussion is often found in neonates in an intensive care unit, however the clinical manifestations can only be found after cellular hypoxia and tissue perfussion disorder occur. Objective:  The study aims to find the ability of hyperlactatemia  status as a prognostic parameter  for infants in Neonatal Intensive Care Unit Level IIIA. Methods : The research was a cohort prospective study using bivariat and multivariat analysis in NICU of Dr. Wahidin Sudirohusodo Hospital from June 2012 to April 2013. The analysis of the lactate level on samples that met the inclusion and exclusion criterias was done immediately after the neonates get into the NICU level IIIA. The capliary lactate level was measured using hand held analyser. The samples were distributed into groups of hyperlactatemia and without hyperlactatemia followed by outcome observation (death or good recovery). The number of subjects were 102 patients consisted of  69 males and 33  females.  Results : The study showed the incidence of hyperlactatemia at NICU leve IIIA was 53,9%. Hyperlactatemia ((p=0.000; IK95% 4.11-56.75.00; AOR 15.28) and chronological age <24 hours (p=0.014; IK95% 1.5037.04; AOR 7.47) was significant in determining the patient’s outcome. Conclusions: The study found that hyperlactatemia status and cronological age less than 24 hours were prognostic factors for patient’s outcome related to elevated mortality risk.   Keywords: Hyperlactatemia, NICU, Critically ill infants
Nasopharyngeal colonization at birth and the development of early-onset neonatal sepsis Andi Dwi Bahagia Febriani; Nilam Sartika Putri; Ema Alasiry; Dasril Daud
Paediatrica Indonesiana Vol 60 No 6 (2020): November 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi60.6.2020.287-92

Abstract

Background Neonatal sepsis is one of the major causes of morbidity and mortality in neonates. Exposure to maternal bacteria during pregnancy or delivery allows for colonization of the normal upper airway. Such bacteria become the major ecological species in the infant. If the colonizing bacteria invade the bloodstream, early-onset neonatal sepsis (EONS) could occur. Objective To evaluate for an association between colonization of the newborn nasopharynx and EONS, as well as for agreement between nasopharyngeal swab culture and blood culture isolate results. Methods This prospective cohort study was conducted in Dr. Wahidin Sudirohusodo General Hospital and Ibnu Sina Hospital, Makassar, South Sulawesi. Nasopharyngeal swab culture was taken within 2 hours of life from newborns who met the inclusion criteria, then they were followed up for signs of EONS. Blood culture was taken from subject with EONS. Results Of the 100 newborns, 69 (69%) had nasopharyngeal bacterial colonization, of whom 5.8% (4/69) experienced EONS. Of the remaining 31 (31%) without colonization, 9.7% (3/31) experienced EONS. There was no significant difference in frequency of EONS between newborns with and without nasopharyngeal colonization. Although Gram-negative bacteria were predominant among colonized newborns, there was no significant difference to numbers of Gram-positive bacteria as a causative agent of EONS. Only one patient with EONS had the same bacterial species in both the nasopharynx and blood culture isolate. Conclusion Newborn nasopharyngeal colonization at birth is not associated with EONS.
ANALYSIS OF MALONDIALDEHYDE LEVELS IN CHILDREN WITH BETA THALASSEMIA: A CROSS-SECTIONAL STUDY Syarifah Raehana Mardiah Alaydrus; Nadirah Rasyid Ridha; Ema Alasiry; Amiruddin L; Hadia Angriani; Kwari Januar Satriono
International Journal of Health Science & Medical Research Vol 2, No 2 (2023): August 2023
Publisher : UNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/ijhsmr.v2i2.18810

Abstract

AbstractBeta thalassemia is an autosomal recessive genetic condition affecting people worldwide, including in Indonesia. Malondialdehyde levels, a peroxidation product, can be used to see if there is an iron buildup in the body due to lifelong transfusions. This research is a novelty because it analyzes malondialdehyde levels in children with beta-thalassemia: a cross-section study. The study aims to analyze malondialdehyde levels in children with beta-thalassemia. Methods in this study, a cross-sectional investigation was carried out at Dr. Hospital Wahidin Sudirohusodo, Makassar. The study was carried out between April and August of 2022. The study sample consisted of participants diagnosed with beta-thalassemia and non-thalassemia (controls) eligible to participate. Patients with and without beta-thalassemia had their malondialdehyde levels measured. The study results showed that the 60 children, aged six months until 18 years, were separated into two groups, 30 of whom had beta-thalassemia and another 30 who did not. With a significant P-value of 0.000, it was determined that beta-thalassemia children had more substantial amounts of malondialdehyde than children without the condition. Children with beta-thalassemia major had significantly higher malondialdehyde levels than those with beta-thalassemia HbE (P-value = 0.000). The conclusion was that malondialdehyde levels were more significant in beta-thalassemia kids than non-thalassemia kids. Malondialdehyde values are more effective in kids with beta-thalassemia major than those with beta-HbE thalassemia.Keywords: Malondialdehyde; Beta thalassemia; Transfusion; Children.
The RELIABILITY AND ACCURACY OF EPICAM M AND RETCAM SHUTTLE COMPARED TO INDIRECT OPHTHALMOSCOPE IN DETECTION OF RETINOPATHY OF PREMATURITY Meiliaty Ariesta Angky; Marliyanti N Akib; Noor Syamsu; Andi Muhammad Ichsan; Habibah S Muhiddin; Ema Alasiry
International Journal of Retina Vol 6 No 2 (2023): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2023.vol006.iss002.233

Abstract

Introduction: In this study, we reported the performance of 2 retinal camera types on premature infants in Retinopathy of Prematurity (ROP) screening. Methods: Premature infants went through : (1) examination by a pediatric ophthalmologist using indirect ophthalmoscopy as a standard of reference; (2) digital imaging by a photographer using EpiCam M and RetCam shuttle. After a month, images were interpreted randomly and single-blinded by the same pediatric ophthalmologist (grader). Result: A total of 44 eyes from 22 premature infants were included in this study (ROP 11 subjects and non-ROP 11 subjects). Detection of ROP with EpiCam M had a moderate agreement (Kappa 0.502, p 0.009) and very good agreement with RetCam shuttle (Kappa 0.862, p <0.0001). Sensitivity, specificity, and accuracy of EpiCam M in detection of ROP were 80.95%, 69.56%, and 75%; RetCam shuttle 85.71%, 100%, and 93.18% respectively. Conclusion: Both EpiCam M and RetCam shuttle displayed significant agreement with indirect ophthalmoscope in detecting ROP. EpiCam M can potentially be allowed to be a viable low-cost alternative device for ROP screening in low resource environments but should be noted that EpiCam M has a high false positive rate which affects its specificity and accuracy rate. Some issues also need to be considered if using epiCam M in telemedicine includes frequent glare and longer duration of documentation
Co-Authors A Dwi Bahagia Amiruddin L Andi Dwi Bahagia Febriani Andi Muhammad Ichsan Dasril Daud Djauharia A.M Habibah S Muhiddin Hadia Angriani Hanna Kurniawati Kwari Januar Satriono Marliyanti N Akib Meiliaty Ariesta Angky Nadirah Rasyid Ridha Nilam Sartika Putri Noor Syamsu Syarifah Raehana Mardiah Alaydrus