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All Journal Jurnal Radioisotop dan Radiofarmaka Medical Journal of Indonesia Jurnal Sains dan Teknologi Farmasi Publikauma : Jurnal Administrasi Publik Universitas Medan Area The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy
Abdul Muthalib
Universitas Medan Area
Computer Science & IT Education Health Professions Medicine & Pharmacology Social Sciences

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Periosteal osteosarcoma: A case report Hutagalung, Errol U.; Librianto, Didik; Gumay, Saukani; Muthalib, Abdul; Budiatmoko, Bambang
Medical Journal of Indonesia Vol 12, No 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (139.892 KB) | DOI: 10.13181/mji.v12i3.104

Abstract

Periosteal osteosarcoma is a rare type of malignant bone neoplasm, with predominantly cartilaginous component and arising on the bone surface. Reports of the case in the literature were rare. Last case was reported by Mayo Clinic in 1999. We report a case of periosteal osteosarcoma in a 17-year-old male, who was treated surgically with a limb salvage procedure, neoadjuvant and adjuvant chemotherapy were also given to the patient. There was no local recurrence and lung metastases up to 14 months after surgery. (Med J Indones 2003; 12: 166-70) Keywords: osteosarcoma, periosteal osteosarcoma, limb salvage
Ewing sarcoma of the left big toe with trans-articular skip lesion Kamal, Ahmad F.; Nagieb, Muhammad; Hutagalung, Errol U.; Budiatmoko, Bambang; Gumay, Saukani; Muthalib, Abdul
Medical Journal of Indonesia Vol 18, No 2 (2009): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3568.325 KB) | DOI: 10.13181/mji.v18i2.346

Abstract

We report the case of the patient who had Ewing Sarcoma in whom radiological and hystopathological appearances revealed a tumor mass in the left big toe along with trans-artikular skip lesion on the left diaphysis of tibia. In Cipto Mangunkusomo Hospital since 1995 until 2004 we have found 20 Ewing sarcoma cases, but only one skip lesion Ewing sarcoma was found. The diagnosis of transarticular skip lesion in association of Ewing sarcoma was confirmed in clinicopathological conferrence. The initial evaluation of all patients included the recording of the medical history, physical examination, and hematological studies. Radiographs of the chest and the site of the primary tumor were made routinely. Systemic staging was performed with use of total-body bone scan. Ray amputation of left big toe and open biopsy from mass of mid-shaft of tibia had been done to confirm the diagnosis. The patient underwent induction chemotherapy and above knee amputation. Ten months after diagnosis, he died because of advanced-distant metastasis. (Med J Indones 2008; 18: 139-44)Key words: Ewing sarcoma, trans-articular skip lesion
The first report of myeloma with IgD κ and free κ in Indonesia Wirawan, Riadi; Utami, Lidya; Muthalib, Abdul
Medical Journal of Indonesia Vol 20, No 3 (2011): August
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1533.474 KB) | DOI: 10.13181/mji.v20i3.451

Abstract

IgD κ myeloma is a rare plasma cell neoplasm case and has never been reported before in Indonesia. In normal condition, IgD level in blood is very low, therefore increase of IgD level in myeloma could be missed by serum protein electrophoresis. A case of a 59 years old female with severe bone pain is reported. In radiology evaluation, there were thoracal compression fracture and thoracal foramen narrowing. For this patient, the myeloma diagnosis was based on WHO criteria, the stage IIIb was based on Durie and Salmon criteria, and bad prognosis with prognostic index stage III diagnosis was based on International Prognostic Index from International Myeloma Working Group, respectively. In serum protein electrophoresis we found a very small monoclonal spike and in immunofi xation there were monoclonal IgD κ and free light chain κ. (Med J Indones 2011; 20:217-21)Keywords: immunofixation, myeloma IgD κ, protein electrophoresis
Pengaruh Budaya Organisasi Terhadap Kinerja Sales di PT. Sumatera Berlian Motors Saputra, Ridho Eko; Muthalib, Abdul
Publikauma : Jurnal Administrasi Publik Universitas Medan Area Vol 4, No 1 (2016): PUBLIKAUMA JUNI
Publisher : Publikauma : Jurnal Administrasi Publik Universitas Medan Area

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Abstract

Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh budaya organisasi terhadap kinerja team sales di PT. Sumatera Berlian Motors. Jumlah populasi pada penelitian ini adalah 53 responden, dan dengan menggunakan metode sampling jenuh maka jumlah sampel adalah 53 responden. Teknik pengumpulan data pada penilitian ini adalah dengan menggunakan kuesioner yang terdiri atas 29 butir soal untuk variabel budaya organisasi dan 27 butir soal untuk variabel kinerja karyawan dengan teknik cronbach alpha diperoleh nilai reliabilitas sebesar 0,864 untuk variabel budaya organisasi dan 0,800 untuk variabel kinerja karyawan. Sedangkan pengujian hipotesis menggunakan uji-t. Berdasarkan hasil perhitungan diperoleh persamaan regresi linier sederhana yaitu Y = 38,461 + 0.489X. Hasil uji determinasi dari nilai R2 adalah 0,213. Uji-t diperoleh thitung = 3,713. Dengan demikian dapat ditarik kesimpulan bahwa terdapat pengaruh positif dan signifikan antara budaya organisasi terhadap kinerja karyawan
Evaluasi Kinerja Pegawai Dalam Pelayanan Bea Balik Nama Kendaraan Bermotor di Kantor Samsat UPT Pangkalan Brandan Nasution, Faisal Reza; Muthalib, Abdul
Publikauma : Jurnal Administrasi Publik Universitas Medan Area Vol 3, No 1 (2015): PUBLIKAUMA JUNI
Publisher : Publikauma : Jurnal Administrasi Publik Universitas Medan Area

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Abstract

Dari latar belakang diatas maka penulis membuat rumusan permasalahan, Bagaimana kinerja pegawai dalam pelayanan Bea Balik Nama Kendaraan Bermotor di kantor Samsat UPT Pangkalan Brandan dan apa saja hambatan dalam pelayanan Bea Balik Nama Kendaraan Bermotor di kantor Samsat UPT Pangkalan Brandan. Berdasarkan rumusan masalah tersebut, maka dapat diketahui salah satu usaha pegawai kantor Samsat UPT Pangkalan Brandan melakukan himbauan  kepada masyarakat melalui media massa, sedangkan hambatan yang dihadapi adalah kurangnya jumlah pegawai yang ada di Kantor Samsat UPT Pangkalan Brandan yang menyebabkan kurang cepat pelayanan dan urusan BBN-KB. Dengan demikian dapat disimpulkan Evaluasi kinerja pegawai kantor Samsat UPT Pangkalan Brandan sudah cukup maksimal dan baik.
Pengaruh Kualitas Pelayanan Terhadap Kepuasan Nasabah PT. Pegadaian (Persero) Cabang Madala Medan Sukamma, Lia Effi; Muthalib, Abdul
Publikauma : Jurnal Administrasi Publik Universitas Medan Area Vol 2, No 1 (2014): PUBLIKAUMA JUNI
Publisher : Publikauma : Jurnal Administrasi Publik Universitas Medan Area

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Abstract

Penelitian ini merupakan jenis penelitian kuantitatif dengan menggunakan analisis produk moment dan selanJutnya diuji melalui uji t serta uji determinasi. Didalam pemberian kredit atau masalah gadai, apabila telah sampai pada waktu pelunasan hutang dan penebusan barang jaminan, tetapi penggadai tidak dapat membayar hutangnya, maka barang jaminan  dilelang dan nasabah masih berhak menerima sisa penjualannya, tetapi jika tidak cukup untuk pembayaran hutang, maka yang berhutang wajib membayar kekuranganny. Hasil penelitian menunjukkkan bahwa terdapat hubungan yang signifikan antara kualitas pelayanan terhadap kepuasan nasabah, Hal ini dibuktikan dengan harga rxy=0,58 berada pada interval antara 0,40-0,599 dimana hubungan yang terjadi sedang. Selanjutnya dengan menggunakan uji t dengan uji 2 pihak dk=28 dan α = 5% maka diperoleh t tabel dengan nilai 2,048, maka t hitung > t tabel (3,393>2,048). Jika ditarik kesimpulan maka terdapat hubungan kualitas pelayanan dengan kepuasan nasabah pada PT. Pegadaian
Uji Kemurnian Dan Stabilitas Radiokimia 153SmCl3 dengan Ligan EDTMP (Ethylene Diamine Tetramethylene Phosphanate) yang Berasal dari Tulang Sapi Fitria, Najmiatul; Djamal, Rusdi; Muthalib, Abdul
Jurnal Sains dan Teknologi Farmasi Vol 17 No 2 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

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Abstract

Purity and stability evaluation post-production of labelled compound 153SmCl3 with EDTMP have been studied. Purity evaluation of 153SmCl3 and 153Sm-EDTMP were conducted using thin layer chromatographic principle on Whatman No.1. Stability evaluation of 153SmCl3 and 153Sm-EDTMP were conducted using visual observation on color and pH changes. Table showes that purity of 153Sm-EDTMP was ± 98- 99 %. It means ± 1-2 % rest was free 153Sm+3 which is left on drop point chromatographic paper. Table also describes t-student analyses that t (-0.545) < t table (2.306). It means storage time did not affect the purity of 153Sm-EDTMP.
Prevalence and Distribution of Anemia Risk Factor in Patient with Chronic Hepatitis C who Has Combination therapy of Interferon Alpha and Ribavirin Akbar, Femmy Nurul; Albar, Zuljasri; Muthalib, Abdul; Lesmana, Laurentius; Akbar, Nurul
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 7, ISSUE 1, April 2006
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.24871/7120066-10

Abstract

Background: Interferon alfa and ribavirin combination therapy is one of effective standard therapy for chronic hepatitis C (CHC.) However, anemia is a common side effect of this therapy that patients have to reduce or discontinue ribavirin therapy. But ribavirin dose reduction or discontinuation can reduce the effectivity of the therapy. Hence, it is important to know the prevalence of anemia and to determine the factors associated with anemia. Objective: To know the prevalence of anemia and some risk factors associated with anemia caused by the combination therapy in chronic hepatitis C. Method: Sixty one of CHC patients who received combination therapy were included in this study. The study used cross sectional design and data were obtained by measured complete blood count on 8th week of therapy. Result: Subjects 47 (77%) were males, 14 (23%) were females with mean age 38.9 years. Subjects had genotype 1 and 4 were 23 (71.9%) and 44 (72.1%) subjects received 1,000 mg ribavirin. Prevalence of anemia was found to be 52.5%. On multivariate analysis, only pretreatment hemoglobin concentration < 14 g/dl was found to be the risk factor of anemia. Conclusion: Prevalence of anemia was 52.5%. Pretreatment hemoglobin concentration < 14 g/dl was only found to be the risk factors of anemia. Although age > 50 years or female were not found to be the risk factor of anemia but patient with these risk factors should be carefully monitored. Intervention to prevent anemia should be considered to these patients. Eight subjects from 32 anemia patients had ribavirin dose reduction, and no patient had discontinuation treatment on 8th week of therapy.   Keywords: chronic hepatitis C, IFN-alfa- RIB combination therapy, risk factors of anemia
PENGARUH PENCUCIAN LARUTAN NaOCI DAN PENAMBAHAN KOLOM KEDUA ALUMINA TERHADAP YIELD DAN LOLOSAN 99Mo DARI GENERATOR 99Mo/99M Tc BERBASIS PZC Gunawan, Adang Hardi; Muthalib, Abdul; Lubis, Hotman; Awaludin, Rohadi; Sulaiman, Sulaiman
Jurnal Radioisotop dan Radiofarmaka Vol 13, No 1 (2010): Jurnal PRR 2010
Publisher : Jurnal Radioisotop dan Radiofarmaka

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Abstract

ABSTRAKPENGARUH PENCUCIAN LARUTAN NaOCI DAN PENAMBAHAN KOLOM KEDUA ALVMINA TEIUIAD~P YIELD DAN LOLOSAN 99Mo DARI G~)NE~~}!OR 99Mo/99mT~BEI~BASIS PZc. Alumina  merupakan salah satu bahan utama dalam generator 99Mo/99mTc yang berfungsi sebagai zat pengadsorpsi molibdenum. Keterbatasan daya serap alumina terhadap molibdenum menyebabkan senyawa ini tidak dapat digunakan sebagai pengisi kolom untuk generator 99Mo99"'Tc yang menggunakan 99Mo  hasil aktivasi neutron. Dengan diketemukannya senyawa bani sebagai zat pengadsorpsi molybdenum yaitu  PZC (poly zirconium compound), telah memberikan harapan banu untuk dapat dilakukannya pembuatan generator 99Mo/ 99"'Tc. Pene litian pembuatan generator 99M0;99"'Tc d engan mengguna k'an senyawa PZC seb,igai adsorbent merupakan bentuk kerjasama antara PRR-BA TAN dengan JAERI dan Kaken Co. Jep1'ng. Dalam penelitian ini telah dilakukan percobaan pembuatan generator 99Mo;9'J"'Tc dengan melihat .. 99 99 pen aruh penambahan pencuclan menggunakan larutan NaOCI terhadap Yield dan lolosan Mo ( Mo bredkthrough) dalam larutan ()9"'Tc hasil elusi. Parameter lainnya yang digunakan untuk mengurangi lolosan ()9M~ dalam 99"'Tc hasil elusi adalah penambahan kolom alumina yang ditempatkan setelah kolom 99Mo_PZc. Hasll penentuan kapasitas serap senyawa PZC terhaclap molibdenum diperoleh dengan melihat aktivitas ()9M4Jsetelah pemanasan 3 jam campuran PZC dan molibdenum dan diperoleh hasil setiap gram PZC mampu 9m9eMn;dyJe;r9a'Jp"'T8c0d-e9n5gan% mlargutadnari pe2n6c8ucmi g samlionlibddiepneuromleh ya<ng50di%reaksdiaknan.yieldHasmilenpinegnkeanttuanmenyjiaedldi e>lus8i0 %genseertaetloarh penqucian dilakukan dengan menggunakan larutan NaOCI 0,5% atau 1%. Penggunaan larutan pencuci NIa~Cld 0,5 % .d.an peIkngguInaa1n99Mkolom alumina sebagai kolom kedua mampu menjaga kestabilan yield hasil J e us an memll1l111a 'an oosan 0 pac a 99"'Tc IlaSI'1 e Ius!.. •. 99 99'J1 Kat» kunCl: alul11111 a, generator PZc, Mo, 'Tc, NaOCI AB~TRACT EFFECT OF NaOCI SOLUTION TREATMENT AND SECOND COLUMN OF ALUMINA ON ITHE YIELD AND BREAKTHROUGH OF Mo-99 FROM Mo-99/Tc-99m GENERATOR BASED ON PZC. Alumina is one of main material in 99Mo;')9"'Tc generator as molybdenum adsorbent. Limitation of alumina adsorption capacity to molybdenum cause this material cannot be applied as column filler for genq.r,ator 9()Mo /')"'T c uSI.ng 99I~V 'I0 from neutron actI.v.ation. TIle I..I1ventlon 0 f a new compoun d as molybdenum adsorbent, PZC (poly zirconium compound), shows that the materials is a promising db' 99 ;99"'T f ( . d' d I b J a sqr ent tor generator Mo c rom n,y) IITa late 1110y clenum. T Ile researc I1' ot generator ()()M~;99"'Tc by using adsorbent PZC is a cooperation between PRR-BA TAN with JAERI and Kaken Co. Japan. In this research, the effects of addition of NaOCI solution to elution yield and 99Mo brea~through have been done. The other parameter used in this experiment to minimize 99Mo breakthrough in 9V"'Tc is addition of second column alumina placed after 99Mo_PZC column. Adsorption capacity of PZC material to molybdenum determined by heating 99Mo solution with PZC up to 3 hours and the result indicated I gram PZC adsorbed 80-95% 99Mo from the reacted 268 mg molybdenum. YielUI percentage of the 99Mo;9'J"'Tc generator without rinsed by saline solution obtained < 50 % and the yielCl increased > 80% after the column washing by using NaOCI 0,5% or I% solutions. Usage of both NadCl 0,5% solution and alumina column as second column can prevent of yield stability and minimized 9() I 99111'" Mf breakthrough at Tc ettluent. • 9<) 99m Ke~vords: Alul11l11a, PZC generator, Mo, Tc , NaOCI.
UJI PRODUKSI Mo-99 HASIL FISI DENGAN BAHAN SASARAN FOIL LEU BUATAN P2TBDU-BATAN Lubis, Hotman; Muthalib, Abdul; Gunawan, Adang H.; Sriyono, Sriyono; Sucipto, Edi; Hambali, Hambali
Jurnal Radioisotop dan Radiofarmaka Vol 8 (2005): JURNAL PRR 2005
Publisher : Jurnal Radioisotop dan Radiofarmaka

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Abstract

UJI PRODUKSI Mo-99 HASIL FISI DENGAN BAHAN SASARAN FOIL LEU BUATAN P2TBDU-BATAN. Selama ini telah dilaksanakan beberapa kali produksi Mo-99 dengan menggunakan bahan sasaran foil LEU buatan Argonne National Laboratory (ANL). Dalam produksi Mo-99 dengan proses Cintichem yang dimodifikasibahan sasaran foil LEU sangat menentukan. Telah dilakukan uji produksi Mo-99 hasil fisi dengan bahan sasaran foil LEU (LEU, < 20% U-235) buatan P2TBDU-BATAN dengan proses Cintichem yang dimodifikasi, meliputi pelarutan foil LEU menggunakan HNO3 9,5N, penarikan gas iodium, proses pemisahan dengan pengendapan α-Benzoin Oxime dan pemurnian Mo-99 melalui kolom kromatografi. Foil LEU larut dengan sempurna selama 30 menit dan penarikan gas iodium dilakukan dengan pendinginan nitrogen cair. Setelah melalui tahap pemisahan (pengendapan) dan pemurnian kolom I dan kolom II radionuklida pengotor masih besar dan aktivitas pengotor pemancar α melebihi persyaratan standard internasional yang ditetapkan yaitu sebesar 7.716E-7 µCi/mCi Mo-99. Kata kunci: produksi Mo-99 HF, Sasaran Foil LEU P2TBDU PRODUCTION TEST OF Mo-99 FISSION PRODUCT USING LEU TARGET FOIL MADE IN P2TBDU – BATAN. Production of Mo-99 fission product using LEU target foil of Argonne National Laboratory (ANL) has been performed several times recently in BATAN. In the production of Mo-99 using modified Cinthichem method, the LEU target foil was very critical. This paper reported production test on Mo-99 fission product using LEU target foil ( LEU < 20% U-235) made by P2TBDU – BATAN using modified Cintichem method. The process included dissolving of LEU foil with 9.5 N HNO3, suctioning of iodine gas, separation process using precipitation with α–benzoin oxime, and purification by column chromatography. The LEU foil was completely dissolved after 30 minutes and gas suction was performed by cooling with liquid nitrogen. After separation and two purification steps, the radionuclide impurities were remained high and activity of αimpurities exceeded international standard requirements, i.e. 7.716E-7 µCi/mCi Mo-99. Key words: Production of Mo-99 FP, Target foil LEU P2TBDU
Co-Authors A.A. Ketut Agung Cahyawan W Abidin Abidin Adang H. Gunawan Adang Hardi Gunawan Ahmad F. Kamal Anung Pujianto Bambang Budiatmoko Didik Librianto Edi Sucipto Eki Mustofa Hamdani Endang Sarmini Errol U. Hutagalung Evi Sovilawati Faisal Reza Nasution, Faisal Reza Femmy Nurul Akbar Hambali Hambali Herlan Setiawan Herlina Herlina Hotman Lubis Indra Saptiama Laurentius Lesmana Lia Effi Sukamma, Lia Effi Lidya Utami Marlina Marlina Muhammad Nagieb Najmiatul Fitria Nurul Akbar Ratna Dini Haryuni Riadi Wirawan Ridho Eko Saputra, Ridho Eko Rohadi Awaludin Rukiah Rukiah Rusdi Djamal SANTI NURBAITI Saukani Gumay Sri Aguswarini Lestiawati Sri Aguswarini Lestyawati Sri Bagiawati Sriyono Sriyono Sulaiman Sulaiman Wira Y. Rahman Zuljasri Albar