Christina Hari Nawangsih Prihharsanti
Departement Of Radiology, Faculty Of Medicine, Universitas Diponegoro, Semarang

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Radiotherapy for Recurrent Keloid: A Case Report Christina Hari Nawangsih Prihharsanti; Muhamad Rizqi Setyarto; Dion Firli Bramantyo
Journal of Biomedicine and Translational Research Vol 6, No 3 (2020): December2020
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v6i3.8473

Abstract

Background: Keloid is a benign growth of connective tissue. There are several risk factors that play a role in keloid growth. Excision surgery is one of the modalities in the treatment of keloids. However, excision surgery alone has a recurrence rate of 45-100%.Case: Male, 37 years old, with complaints arising from a keloid lesions in the left earlobe since three years ago with a history of previous injuries. The lesions is then operated on but always grows back postoperatively. The number of surgeries that have been carried out three times with further treatment in the form of corticosteroid injection. However, keloid still recurrence. Finally it was decided to undergo treatment with surgery followed by radiotherapy within a period of no more than 24 hours postoperatively. Follow-up after six months gave good results without recurrence.Discussion: Keloid has a high recurrence rate after excision surgery. Surgery followed by radiotherapy has a low recurrence rate compared to surgery or surgery followed by administration of corticosteroid injections. Radiotherapy as adjuvant therapy for postoperative keloid excision has the role of sterilizing the connective tissue stem cell active fibroblasts and acute inflammatory cells that grow in the early postoperative period. A study states that administration of postoperative radiation with electrons in keloids in the earlobe at a dose of 15 Gy in three fractions gives a low recurrence rate and a low risk of side effects in the surrounding soft tissue. 
The Correlation Between Cobb’s Angle and Pedicle Rotation in Adolescent Idiopathic Scoliosis After Surgical Treatment Danu Purnama Aji; Hermina Sukmaningtyas; Agus Priambodo; Christina Hari Nawangsih
Diponegoro International Medical Journal Vol 2, No 1 (2021): July
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v2i1.9531

Abstract

Background: Adolescent Idiopathic Scoliosis (AIS) is a 3-dimensional deformity that involves not only curve in the coronal and sagittal planes but also rotation of vertebrae based on pedicle rotation. The Cobb’s angle is  the gold standard for measuring the lateral curve that could show severity of the spine deformity. The Cobb’s method only evaluate the lateral curve,and the method to determine the pedicle rotation can be used the Nash and Moe’s method.The higher pedicle rotation grade had higher Cobb’s angle. Surgical treatment for scoliosis is indicated for the curve exceeding 40o. Posterior spinal fusion is the most commonly used technique in scoliosis surgery.Objective: To identify the correlation between the Cobb’s Angle and pedicle rotation in AIS after surgical treatment.Methods: The research design used in this study was Cross Sectional. The sample size of this study were 22 subjects using purposive sampling, the independent variable of this study was Cobb’s angle while the dependent variable was pedicle rotation. Spearman’s rank correlation was used to analyze the correlation between variable.Results: The spearman’s rank correlation revealed a significant correlation between the Cobb’s Angle and pedicle rotation in AIS after surgical treatment with the  p 0,005 and r 0,462.Conclusion: This study demonstrates there is a significant correlation between Cobb’s angle and pedicle rotation in AIS after surgical treatment with medium strength. 
THE INCIDENCE OF RADIATION PNEUMONITIS IN BREAST CANCER PATIENTS WHO RECEIVED RADIOTHERAPY USING 3-DIMENSIONAL TECHNIQUES Salsabila Lutfiarahma; Yan Wisnu Prajoko; Farah Hendara Ningrum; Christina Hari Nawangsih Prihharsanti
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 4 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i4.31778

Abstract

Background: According to the 2018 Global Cancer Observatory from the World Health Organization (WHO), breast cancer is the most common cancer in Indonesia. 3-dimensional conformal radiotherapy (3D-CRT) is one of the breast cancer treatment planning. Effect of radiation on the lungs can cause radiation pneumonitis. The incidence rate of pneumonitis in breast cancer patients who received radiotherapy using 3D-CRT techniques from several researchers is still varied and there is no accurate data yet at RSUP Dr. Kariadi.Objective: To determine the incidence of pneumonitis in breast cancer patients undergoing breast cancer 3D-CRT.Methods: The research design used in this study was cross sectional. The subject is chosen by consecutive sampling methods. The independent variables of this study was 3D breast cancer radiation therapy, while the dependent variable was radiation pneumonitis. This hypothesis test on this study is analyzed with chi-square test.Results: Forty one subjects were included in this study, two subjects were found with a picture of pneumonitis on chest radiographs. The incidence of radiation pneumonitis in breast cancer patients who received radiotherapy using 3-dimensional techniques was 4.9%. There is no significant relationship between breast cancer radiation therapy 3-dimensional techniques on the incidence of pneumonitis. And there was no significant difference in the proportion of pneumonitis in patients with breast cancer locations on the right and left sides.Conclusion: The incidence of radiation pneumonitis in breast cancer patients who received radiotherapy using a 3-dimensional technique is 4.9%.   Keywords: 3 Dimensional Technique Radiotherapy, Breast Cancer, Radiation Pneumonitis