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All Journal Folia Medica Indonesiana JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indian Journal of Forensic Medicine & Toxicology Forum Ilmiah Pendidikan Akuntansi (FIPA)
Lina Lukitasari, M.Si
Departement Of Medical Biochemistry, Faculty Of Medicine, Universitas Airlangga, Surabaya
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Mung Bean Sprouts (Vigna radiata) Ethanol Extract on Alanine Aminotransferase (ALT) Activity and Malondialdehyde (MDA) Levels in Toluene-Induced Rats Putu Bayu Agus S.Si; Siti Khaerunnisa M.Si; Lina Lukitasari, M.Si
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17607

Abstract

Objective –This study aimed to evaluate the effect ofethanol extract from mung bean sprouts on alanine aminotransferase (ALT) activity and malondialdehyde levels in toluene-induced white rats.Methods–This research is an experimental laboratory with a research design that is post-test only control group design using 40 rats (Rattus norvegicus) which were divided randomly into 5 groups, G1 (control without toluene), G2 (900 mg/kg toluene), G3 (mung bean sprouts extract 250 mg/kg + 900 mg/kg toluene), G4 (mung bean sprouts extract 500 mg/kg + 900 mg/kg toluene), G5 (mung bean sprouts extract 1000 mg/kg + 900 mg/kg toluene). ALT measurement using spectrophotometer method. Measurement of MDA using the ELISA method. The data collected will be statistically tested with the help of SPSS with a significant (p <0.05).Results–The results of the measurement of ALT activity (p=0.972) and MDA levels (p=0.190) in each group had no significant effect (p>0.05) in each treatment.Conclusion–It can be concluded that there was no significant effect of ethanol extract of sprouts on alanine aminotransferase (ALT) activity and malondialdehyde levels in white rats (Rattus norvegicus) induced by oral toluene.
Prevention and Early Detection of Metabolic Syndrome in Household Community, Surabaya Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Siti Khaerunnisa; Gwenny Ichsan Prabowo; Suhartati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15747

Abstract

Introduction. Metabolic syndrome is a collection of factors believed to increase the risk of atherosclerosis and type 2 diabetes mellitus. The incidence of metabolic syndrome in young adults is increasing, especially in Asian countries. Therefore we need efforts to increase knowledge in society about this disease. Aim. We conducted a socialization program on prevention and early detection of metabolic syndrome in household community to increase public knowledge about this disease.Method. This program was conducted in August 2017 in Wonokromo District, Surabaya. The participants in the activity consisted of 32 people from household community. The activity consisted of blood sampling collection, body weight, and abdominal circumference measurement for risk factor assessment, pre-test, socialization of metabolic syndrome, and post-test.Results. From the results of the pre and post test, we found an increase knowledge of 76.9% participants. The laboratory test results for early detection of metabolic syndrome showed 37.5% of participants had metabolic syndrome. We also found a significant positive correlation between body weight and abdominal circumference (p = 0.000, r = 0.867). There was also a significant negative correlation between body weight and HDL (p = 0.004, r = -0.494), between abdominal circumference and HDL (p <0.05, r = -0.376), and between TG and HDL (p <0.05, r = -4.22).Conclusion. Socialization and early detection of metabolic syndrome can increase knowledge, awareness, and detection of metabolic syndrome in the household community.
The Improvement of Community Knowledge, Attitudes and Practices After Covid-19 Socialization Siti Khaerunnisa; Irmi Syafa'ah; Citrawati Dyah Kencono Wungu; Gwenny Ichsan Prabowo; Retno Handajani; Indri Safitri; Harianto Notopuro; Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Arief Bakhtiar; Suwandito Suwandito; Susi Wahyuning Asih; Zuhrotul Eka Yulis Anggraeni; Ginanjar Sasmito Adi; Ely Rahmatika Nugrahani; Ayesie Natasha Zulka; Soetjipto Soetjipto
Folia Medica Indonesiana Vol. 57 No. 2 (2021): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.653 KB) | DOI: 10.20473/fmi.v57i2.26262

Abstract

This study determined community knowledge, attitudes, and practices after COVID-19 socialization in Rambipuji and Suci Village, Jember District, East Java, Indonesia. This study used the analytic observational design study. As many as 40 people were given socialization about COVID-19 by gathering and online. The questionnaires were completed in two parts included before-socialization and after-socialization. The questionnaire data were analyzed descriptively by calculating frequency, percentage, and inferential statistics by t-test, Spearman correlation, and chi-square test. The data analysis used IBM SPSS version 23 software. The mean and standard deviation of percentage of knowledge pre-test, knowledge post-test, high attitude, moderate attitude, low attitude, very high practice, high practice, sufficient practice, and low practice were 58.33 ± 30.97, 77.70 ± 22.52, 62.5±21.7, 31±22.2, 6.5±17.1, 65±13.8, 32.3±13.8, 1.25±2.4, 1.25±1.8, respectively. Knowledge pre-test and post-test correlated 0.819 (p=0.001) and a t-test with p=0.003. Attitudes and practices correlated with p=0.001. Socialization of COVID-19 was useful to improve the community knowledge, attitudes, and practices in Rambipuji and Suci Village, Jember District, East Java, Indonesia that could prevent the transmission and inhibit the spread of the COVID-19 pandemic in Indonesia. Furthermore, continuous encouragement of COVID-19 socialization in wide areas was recommended.
High Calorie Diet with a Combination of Intermittent Restriction Affects the Reproductive Cycle and The Uterine Weight of Mice (Mus Musculus) Anggraeni Dyah Kumalasari; Lilik Herawati; Raden Argarini; Lina Lukitasari; Zulhabri Othman; Astika Gita Ningrum
Folia Medica Indonesiana Vol. 57 No. 4 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (812.554 KB) | DOI: 10.20473/fmi.v57i4.29115

Abstract

Highlight:High-calorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice were analyzed.Calories balance impact for female reproductive health. Abstract :Balanced calories affected for body health and daily activities. Lose of energy can disturb the health and daily activities, while over calorie for diets also causes disorders such as metabolic. When there are excess calories in the body will be involved. It can be an obesity risk, diabetes mellitus, fertility disorder, cancer, and cardiovascular disease. Furthermore, in women there can be an increase in menstrual disorders and fertility disorder risk (Silvestris et al., 2018). This study aims to analyze highcalorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice. Experimental laboratory is a mouse (mus musculus) female’s balb/c as object population. Sampling techniques using probability sampling with simple random sampling type. The study results on fisher's exact test gave a result of p > 0.05 so there was no significant difference between control group, high calorie diet group, and high calorie diet with interval restrictions group on the results of vaginal swabs /post-treatment reproductive cycle. The study outcome on robust tests between control, high calorie diet, and high calorie diet with interval restrictions groups. Obtained results (p < 0.05) that mean there are some significant discrepancies in the weight of uterine organ between groups. Calories balance in the body can impact female reproductive health.
APRI Profile of Cirrhotic Patients with Positive HBsAg Nadya Husni; Leonita Anniwati; Lina Lukitasari
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.482 KB) | DOI: 10.20473/juxta.V10I12019.34-37

Abstract

Introduction: Hepatitis B is a viral infection that has the potency to become chronic infection and cause serious complications such as liver cirrhosis and hepatocellular carcinoma. One of the tools in diagnosing hepatitis B or cirrhosis and predicting the prognosis is aspartate aminotransferase to platelet ratio index (APRI). The purpose of this study is to evaluate the profile of APRI among cirrhotic patients with positive hepatitis B surface antigen (HBsAg).Method: This research was a descriptive observational study. The number of samples was 35 cirrhotic patients with positive HBsAg in RSUD Dr. Soetomo Surabaya from January-December 2017.Results: The majority of cirrhotic patients had >1,5 APRI score (48,57%). The most prevalent APRI score in Child A patients for first classification was 0,5 – 1,5 (5,71%) while for second classification was 0,7 – 1,5 (5,71%). The most prevalent APRI score in Child B patients for first classification was 0,5 – 1,5 (17,14%) while for second classification was 0,7 – 1,5 (11,43%). Most of Child C patients had >1,5 APRI score (22,86%). The majority of malignant degeneration patients also had >1,5 APRI score (14,29%).Conclusion: The majority of cirrhotic patients had >1,5 APRI score. In cirrhotic patients with Child A or B classification, the increase of APRI score was not as much as those with Child C or malignant degeneration classification.Keywords: Hepatitis B, cirrhosis, liver, hepatocellular carcinoma, APRI
SARI ETANOL, ETIL ASETAT ALANG-ALANG (IMPERATA CYLINDRICA) TERHADAP SUPEROXIDE DISMUTASE (SOD) St Khaerunnisa; Sutji Kuswarini; Suhartati Suhartati; Lina Lukitasari; Ira Humairah; Reza Arta BN; Gwenny IP
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 20, No 2 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v20i2.1080

Abstract

Oxidative stress has been considered as a mechanism involved in the pathogenesis and progression of many diseases such as:hypercholesterolemia and atherosclerosis. The objective of this current study was to know the potential antioxidant role of ethanol andethyl acetate extract of reeds (Imperata cylindrica) by investigation in rats fed with a high-cholesterol diet. Imperata cylindrica is richin antioxidants and has a cholesterol-reducing effect. A group of twenty four male albino Wistar rats was divided into four subgroups: anormal diet group (K0), a high-cholesterol diet group (K1), the same diet with ethanol extract of Imperata cylindrica group (K2), and thesimilar diet with ethyl acetate fraction of Imperata cylindrica group (K3),. After the treatment period, the hepatic antioxidant enzymeactivity (Superoxide dismutase/SOD) was determined. The rats fed on high-cholesterol diet with supplementation exhibited a significantelevation in SOD activity (p<0. 05), 61.6±12.4% inhibition, compared to normal animals 37.44±12.2%. The treated animals withethanol and ethyl acetate extract of Imperata cylindrica showed a significantly reduced the level of SOD activity (p<0.05, 29.90±5.6%as well as a 33.49±7.4% inhibition). The level of SOD activity when restored was closer to that in normal animals, signifying reversalof the oxidative stress. The study results showed that the treatment with Imperata cylindrica positively changed the hepatic antioxidantenzyme activities in high fat-diet rats, and thus had potential hypocholesterolemic and antioxidant effects. Imperata cylindrica couldprotect against oxidative stress linked to atherosclerosis and also decrease the atherogenic index.
PENGARUH PELAKASANAAN PROGRAM KESEJAHTERAAN JAMINAN SOSIAL, INSENTIF DAN PELATIHAN KERJA TERHADAP PRODUKTIVITAS KARYAWAN CV. IJO GENENG NGAWI Lina Lukitasari
FIPA : Forum Ilmiah Pendidikan Akuntansi Vol 3, No 1 (2015): FIPA 5
Publisher : FIPA : Forum Ilmiah Pendidikan Akuntansi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.912 KB)

Abstract

Produktivitas suatu perusahaan menggambarkan kinerja yang ada didalam sebuah perusahaan, dan mencerminkan berhasil tidaknya sistem kerja didalam menghasilkan output berupa barang atau jasa. Penelitian ini bertujuan untuk menguji pengaruh jaminan sosial, insentif dan pelatihan kerja secara parsial dan silmutan terhadap produktivitas karyawan pada CV. IJO Geneng Ngawi.    Populasi dalam penelitian ini adalah seluruh karyawan bagian produksi CV. IJO Geneng Ngawi, yaitu sebanyak 45 karyawan. Teknik pengambilan sampel dilakukan dengan sampling jenuh sehingga jumlah sampel yang diperoleh sebanyak 33 karyawan bagian produksi. Teknik pengumpulan data dilakukan dengan menggunakan kuesioner, observasi dan wawancara. Metode analisis yang digunakan adalah regresi linier berganda. Hasil penelitian ini menunjukkan bahwa jaminan sosial, insentif dan pelatihan kerja berpengaruh signifikan secara simultan terhadap produktivitas karyawan. Secara parsial jaminan sosial tidak berpengaruh signifikan terhadap produktivitas karyawan. Sedangkan insentif dan pelatihan kerja berpengaruh positif dan signifikan terhadap produktivitas karyawan.  Kata Kunci : Produktivitas Karyawan, Jaminan Sosial, Insentif, Pelatihan Kerja.
Co-Authors Anggraeni Dyah Kumalasari Ayesie Natasha Zulka Bakhtiar, Arief Citrawati Dyah Kencono Wungu Ely Rahmatika Nugrahani Ema Qurnianingsih Ginanjar Sasmito Adi Gwenny IP Harianto Notopuro HERAWATI, LILIK Indri Safitri Ira Humairah Ira Humairah Irmi Syafa'ah Leonita Anniwati Nadya Husni Ningrum, Astika Gita Prabowo, Gwenny Ichsan Putu Bayu Agus S.Si Raden Argarini Retno Handajani Reza Arta BN Siti Khaerunnisa Siti Khaerunnisa Siti Khaerunnisa M.Si Soetjipto Soetjipto St Khaerunnisa Suhartati Suhartati Suhartati Susi Wahyuning Asih Sutji Kuswarini Suwandito Suwandito Zuhrotul Eka Yulis Anggraeni Zulhabri Othman