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RELATIONSHIP BETWEEN LEVEL OF SERUM ADIPONECTIN AND FRAILTY IN ELDERLY PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE Erika Marfiani; Jusri Ichwani; Novira Widajanti; Daniel Maranatha; Muhammad Amin
Indonesian Journal of Tropical and Infectious Disease Vol. 8 No. 2 (2020)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v8i2.16027

Abstract

Elderly are especially prone to the adverse health effects of chronic obstructive pulmonary disease (COPD). COPD is a typical aging disease which is found to be about 12% in the age group more than 64 years old. Frailty is an important geriatics syndrome, while adiponectin is an important adipokine that regulate homeostasis of energy. Adiponectin is affected by age, especially in males. Adiponectin levels increases as subcutaneous fat cells in older men decreases. Increased adiponectin can lead to muscle wasting which will further reduce body weight and body mass index (BMI), which indirectly also increases the degree of frailty. Until now the relationship between adiponectin with frailty degree in advanced COPD is still unknown.The aims of this study was to investigate the relationship between plasma adiponectin level and frailty in COPD elders. This was an observational analytic cross-sectional study. All anthropometric parameters, including weight, height, and body mass index (BMI), were measured. Adiponectin was measured by ELISA methods obtained from venous blood samples. Aged more than or equal to 60 years old, the patients underwent spirometry to determine the degree of airflow limitation and the degree of frailty defined by the Fried criteria. Statistic analysis used Rank Spearman. Thirty-eight male COPD patients became the subject of the study. The average age was 70-74 years, with a total of 13 robust, 12 prefrails and 13 frail patients. Level of adiponectin (mean and SD) in robust, prefrail, and frail were 6.84+ 2.66 , 6.58 + 4.27, and 11.62 + 4.90 respectively, p=0.015. Further analysis showed that level of adiponectin rose progresively with an increasing number of components of frailty. The degree of obstruction mostly with mild (42.1%), and no subjects with very severe. There were an increase in serum adiponectin levels in all subjects. In conclusion, level of adiponectin serum correlates positively with the degree of frailty.
Clinical and Demographic Characteristics Differences between M. tuberculosis and M. bovis Infection in Bronchoalveolar Lavage Pulmonary TB Patients, Indonesia Budi Yanti; Soetjipto Soetjipto; Ni Made Mertaniasih; Muhammad Amin
Jurnal Respirologi Indonesia Vol 39, No 4 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v39i4.76

Abstract

Background: Some species of the Mycobacterium tuberculosis complex (MTBC) which can cause tuberculosis, particularly M. tuberculosis and M. bovis, may have different virulence property and therefore associated with various clinical severity in tuberculosis (TB) patients. The aim of this study was to determine the differences in clinical and demographic characteristics between M. tuberculosis and M. bovis infection among Indonesian TB patients. Methods: Thirty-one new and active TB patients were confirmed to have acid fast bacilli (AFB) sputum positive and/or Xpert MTB/RIF positive for M. tuberculosis from Dr. Soewandhie Hospital, Surabaya, Indonesia. Interviews were conducted to record the clinical and demographics required. The MTBC were isolated from bronchoalveolar lavage fluid (BALF) and determined by primer-specific PCR targeting TbD1 and RD9 region gene. The degree of lung tissue damage was classified using NICE Scoring System. Results: The MTBC were detected in all patients on whom 19 and 12 isolates were classified as M. tuberculosis and M. bovis respectively. There was a different on 74.2% of productive age subjects (21-50 years) with M. tuberculosis infection (P
Pengetahuan, Gangguan Psikologis, dan Burnout Dokter Umum di Era Pandemi Covid-19 Alfian Nur Rosyid; Arina Dery Puspitasari; Tamara Nur Budiarti; Izzatul Fitriyah; Anggraini Dwi Sensusiati; Muhammad Amin
Jurnal Pengabdian Pada Masyarakat Vol 6 No 3 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202163.838

Abstract

KNOWLEDGE, PSYCHOLOGICAL DISORDERS, AND BURNOUT OF GENERAL PRACTITIONERS IN THE COVID-19 PANDEMIC ERA. High demand in work during the Covid-19 pandemic will cause psychological problems for general practitioners. These psychological disorders can cause burnout. The incidence of burnout is exacerbated by the lack of knowledge of general practitioners about the current condition. This study aims to determine the level of knowledge, psychological disorders, and burnout of general practitioners during the Covid-19 pandemic. The research design using quasi-experimental with one group pre posttest design without a control group. The population in this study was all participants that join the online seminar. Samples taken were 111 respondents with the total sampling technique. The data collection technique was done by using a questionnaire. The data obtained were analyzed using the Wilcoxon test and Kendall's tau-c test. The difference test before and after being given the seminar material shows a p-value of 0.001. The statistical analysis of the relationship between knowledge and burnout shows a p-value of 0.048. The statistical analysis of the relationship between stress and burnout shows a p-value of 0.026. The statistical analysis of the relationship between anxiety and burnout shows a p-value of 0.001. The statistical analysis of the relationship between depression and burnout showed a p-value of 0.002. There are differences in the knowledge of respondents before and after being given the seminar material. There is an association between knowledge with burnout, stress with burnout, anxiety with burnout, and depression with burnout.
Acceptance and Commitment Therapy on Depression of Pulmonary Tuberculosis Patient: An Intervention Based on the Health Belief Model Gevi Melliya Sari; Muhammad Amin; Laily Hidayati
INDONESIAN NURSING JOURNAL OF EDUCATION AND CLINIC (INJEC) Vol 5, No 2 (2020): INJEC
Publisher : Asosiasi Institusi Pendidikan Ners Indonesia (AIPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.262 KB) | DOI: 10.24990/injec.v5i2.290

Abstract

Introduction: Depression is a psychological disorder often experienced by patients undergoing tuberculosis treatment. The purpose of this study was to determine the effect of acceptance and commitment therapy based on the health belief model on the depression of pulmonary tuberculosis patients. Methods: This research used a quantitative quasi-experiment design with pre-posttest control group design. There were 56 respondents in this study selected using consecutive sampling   among the Primary Healthcare Center in Sidoarjo district. The independent variables were acceptance and commitment therapy based on the health belief model. The dependent variable was depression. Measurement of depression used the Beck Depression inventory II questionnaire. Analysis of the data in this study used the Wilcoxon Signed Rank Test and Mann-Whitney U Test. Results: The results showed that the treatment group p=0.000 (p<0.05) and control group p=0.000 (p<0.05), but the delta of the treatment group higher than the control group (delta: -9.79). There were differences in depression values obtained between the treatment group and the control group p=0.001 (p<0.05). Conclusion: Acceptance and commitment therapy based on the health belief model given four sessions for 30-45 minutes each session can lower depression level in pulmonary tuberculosis patients rather than a single intervention of health education. This intervention can be used by nurses to help pulmonary tuberculosis patients overcome psychological problems during treatment.
Studi Perbandingan Histopatologi Udang Vaname yang Terinfeksi Vibrio parahaemolyticus dari Tiga Tambak Berbeda Asmaul Khusnah; Woro Hastuti Satyantini; Muhammad Amin
Grouper: Jurnal Ilmiah Fakultas Perikanan Universitas Islam Lamongan Vol. 14 No. 2 (2023): Grouper: Jurnal Ilmiah Perikanan
Publisher : Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/grouper.v14i2.212

Abstract

Udang vaname merupakan salah satu jenis udang yang memiliki nilai ekonomis tinggi. Hal ini dikarenakan banyaknya permintaan konsumen terhadap udang vaname. Namun budidaya udang vaname tidak mudah, komoditas tersebut mudah terserang penyakit apabila padat tebar terlalu tinggi dan kualitas air yang buruk. Kualitas air yang buruk dapat mengakibatkan imunitas udang vaname menurun dan mengakibatkan mudah terserang penyakit salah satunya Acute Hepatopancreatic Necrosis Disease (AHPND). Penyakit tersebut dilaporkan salah satunya diakibatkan oleh adanya barkteri Vibrio parahaemolyticus yang menginfeksi udang. Tujuan penelitian ini adalah untuk mengetahui kerusakan jaringan udang vaname yang terinfeksi bakteri Vibrio parahaemolyticus di tiga tambak yang berbeda. Metode yang digunakan pada penelitian ini adalah purposive sampling dengan metode observasi. Teknik pengumpulan data dilakukan dengan cara observasi lapang, yakni mengumpulkan data-data primer dan sekunder di lapangan. Data diambil dari tiga lokasi, yaitu Tuban, Sidoarjo dan Pasuruan. Hasil histopatologi dilakukan skoring kerusakan kemudian dianalisis dengan IBM SPSS menggunakan Uji Kruskal Wallis dan dilanjutkan Uji Z. Berdasarkan hasil penelitian menunjukkan bahwa kerusakan jaringan pada insang dan hepatopankreas akibat infeksi dari bakteri V.parahaemolyticus memiliki kerusakan yang cukup parah. Kerusakan yang terjadi pada insang mulai dari fusi lamella dan edema. Sedangkan kerusakan yang terjadi pada hepatopankreas adalah peluruhan sel dan infiltrasi. Maka dapat disimpulkan bahwa ketiga tempat yang terinfeksi V.parahaemolyticus terdapat perbedaan tingkat kerusakan jaringan hepatopankreas dan insang pada udang vaname yang terjadi pada hepatopankreas dan insang banyak hingga sangat banyak. Kerusakan terbanyak terjadi pada sampel udang yang berasal dari Kabupaten Sidoarjo