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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy)

Wida Ningsih

Unknown Affiliation

Author-ID : 330733

Medicine & Pharmacology

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FORMULASI SABUN PEMBERSIH KEWANITAAN (Feminime Hygiene) DARI MINYAK ATSIRI RIMPANG LENGKUAS PUTIH (Alpinia galanga L) DAN UJI AKTIFITAS ANTISEPTIK TERHADAP Candida albicans Wida Ningsih; Diana Agustin; Putri Sefrianti
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 1 Juni 2019
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACTCandida albicans is a normal flora in the female genitalia which can cause vaginal discharge. White galangal rhizome contains essential oils of eugenol which have activities that inhibit the growth of Candida albicans. This study formulated the white galangal rhizome essential oil in the form of feminime hygiene to make it easier and more comfortable to use and to determine the antiseptic feminime hygiene activity of the white galangal rhizome oil of Candida albicans. The essential oil of white galangal rhizome is formulated in three variations of concentration namely 10%, 15% and 20%. Feminime hygiene of essential white galangal rhizome oil was evaluated such as organoleptic, homogeneity, specific gravity, foam power test, viscosity, pH and stability. Antiseptic activity testing was tested with SDA (Sabouraud Dextrose Agar) media and using agar diffusion method. The results of the feminime hygiene evaluation formulated showed results similar to the results of comparative evaluations (BN). The parameters of antiseptic activity are indicated by the formation of inhibitory zone diameters where F0 (negative control), F1 (10%), F2 (15%), and F3 (20%) respectively have an average diameter value of 11 mm, 14.65 mm 17.58 mm and 25.41 mm. The classification category of the response to microbial growth according to CLSI, F0 and F1 includes the weak group, the F2 is the moderate group and the F3 is the strong group. Based on the results of one-way ANOVA statistical analysis there were significant differences in liquid soap preparations F0, F1, F2 with F3 at (P <0.05). White galangal rhizome essential oil can be formulated into feminine hygiene and has antiseptic activity against the fungus Candida albicans.Keywords: white galangal, antiseptic, candida albicans

FORMULASI DAN UJI EFEKTIVITAS ANTIBAKTERI EDIBLE FILM EKSTRAK BIJI PINANG (Areca catechu Linn) Wida Ningsih
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Vol 15 No 2 Desember 2018
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACTThe tannins contained in areca nut extract can inhibit the growth of Streptococcus mutans bacteria. To facilitate the use of betel seed extract as an antibacterial, it was formulated into an edible film with a concentration of 2.5%, 3% and 3.5%. Making edible films using solvent casting method and testing antibacterial activity using blood agar diffusion method. The edible film of areca nut extract made an evaluation included organoleptic, thickness, brittleness, water content, pH, and swelling test. The evaluation results of betel nut edible fim extract showed almost the same characteristics as the edible fim that had been circulating in the market which was used as a comparison. The presence of antibacterial activity from edible pinang seed extract is marked by the formation of clear zones. The test results of antibacterial edible activity of areca nut extract films 2.5%, 3% and 3.5% showed the average diameter of clear zone was 14.96 mm, 15.49 mm and 17.05 mm which were included in the strong category.Keywords: Areca catechu Linn, antibacterial, edible film, tannin, streptococcus

FORMULASI TABLET KUNYAH KALSIUM LAKTAT DENGAN VARIASI KONSENTRASI HPMC SEBAGAI BAHAN PENGIKAT TERHADAP SIFAT FISIKNYA Wida Ningsih; Firmansyah Firmansyah; Nova Jumaynah
Jurnal Ilmu Farmasi dan Farmasi Klinik Jurnal Ilmu Farmasi & Farmasi Klinik Vol 14 No 1 juni 2017
Publisher : Universitas Wahid Hasyim Semarang

INTISARI Telah dilakukan penelitian formulasi tablet kunyah kalsium laktat dengan menggunakan HPMC (Hydroxypropyl Methyl Cellulose) sebagai bahan pengikat menggunakan metoda granulasi basah. Pada penelitian ini dibuat empat formula (FI, FII, FIII, dan FIV) dengan perbedaan konsentrasi bahan pengikat yaitu 1%, 2%, 3%, dan 4%. Evaluasi granul tablet kunyah meliputi organoleptis, kandungan air, kecepatan alir, sudut istirahat, bobot jenis nyata, bobot jenis mampat, bobot jenis benar, porositas, faktor hausner, dan kompresibilitas memberikan hasil yang memenuhi persyaratan. Evaluasi tablet kunyah meliputi organoleptis, keseragaman bobot, kekerasan, kerapuhan tablet dan penetapan kadar kalsium laktat memenuhi persyaratan, sedangkan keseragaman ukuran belum memenuhi persyaratan. Hasil uji terhadap panelis dari keempat formula secara statistik dengan menggunakan metoda Kruskal-Wallis dari segi rasa FII lebih disukai dari pada FI, FIII, dan FIV. Kata kunci : (HPMC), Kalsium Laktat, Tablet Kunyah ABSTRACT Various formulations of the calcium lactate chewable tablets have been done by wet granulation method using HPMC (Hydroxypropyl Methyl Cellulose) as a binding agent. Here, four formulations (FI, FII, FIII, and FIV) were prepared by adding different concentrations of binding agent, it was 1%, 2%, 3%, and 4%. Granules of chewable tablets were qualified based on evaluations for parameters such as organoleptic, water content, flowrate, angle of repose, real density, tapped density, bulk density, Hausner’s ratio, and compressibility index. Chewable tablets evaluations for organoleptic, weight variation, hardness, friability, and determinations of calcium lactate content were within the acceptance criteria, but not for its size variation. The result of panelists test of the four formulations by using Kruskal-Wallis method statistically which in terms of taste obtained FII is preferred than FI, FIII, and FIV. Keywords : HPMC, calsium lactate, tablets

ANALISIS MERKURI (Hg) PADA LOTION PEMUTIH YANG BEREDAR DI PASAR RAYA KOTA PADANG MENGGUNAKAN SPEKTROFOTOMETER SERAPAN ATOM Afdhil Arel; Regina Andayani; Aulia Rahmi; Wida Ningsih
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 16, No 02 (2019): Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 02 Desember 2019
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Whitening lotion is a mixture of chemicals or other ingredients with properties that can whiten the skin or blemish black (brown) on the skin. The use of mercury in whitening lotions can cause a variety of things, ranging from skin discoloration which can ultimately cause black spots on the skin, allergies and skin irritation. The using of mercury in high dose can cause permanent brain damageand cancer. An analysis of mercury content in the whitening lotion brands A, B and C circulating at market in Padang city has been conducted. Extraction of mercury in the whitening lotion was done by wet destruction with a concentrated HNO3 solution and concentrated H2SO4 for 2 hours at a temperature of ± 95°C until a clear solution is obtained. The clear solution was measured by absorption with an Atomic Absorption Spectrophotometer using a mercury hollow cathode lamp at a wavelength of 253.7 nm. The results of this study were samples of brands A, B and C detected containing mercury metals with successive levels of 0.3347 μg /g; 0,7917 μg /g and 0,7981 μg/ g. The whitening lotions that circulate in market do not meet the Head of BPOM RI Regulation No.18 of 2015 whose contents prohibit the use of mercury in cosmetics preparations. Keywords: mercury, whitening lotion, Atomic Absorption Spectrophotometer

Co-Authors Afdhil Arel Aulia Rahmi Diana Agustin Firmansyah Firmansyah Nova Jumaynah Putri Sefrianti Regina Handayani Handayani, Regina Handayani

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