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All Journal Indonesian Journal of Forestry Research Jurnal Penelitian Hasil Hutan
Gunawan Pasaribu
Pusat Litbang Keteknikan Kehutanan dan Pengolahan Hasil Hutan, Jl. Gunung Batu No.5 Bogor Jawa Barat
Agriculture, Biological Sciences & Forestry Decision Sciences, Operations Research & Management

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EFFECT OF SAPPAN WOOD (Caesalpinia sappan L) EXTRACT ON BLOOD GLUCOSE LEVEL IN WHITE RATS Saefudin, Saefudin; Pasaribu, Gunawan; Sofnie, Sofnie; Basri, Efrida
Indonesian Journal of Forestry Research Vol 1, No 2 (2014): Indonesian Journal of Forestry Research
Publisher : Secretariat of Forestry Research and Development Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/ijfr.2014.1.2.109-115

Abstract

Sappan wood or kayu secang (Caesalpinia sappan L.) was reported of having medicinal properties,  such as  natural antioxidant, relieve vomiting of blood, and mix of ingredients for malaria drugs.  The research was conducted to study the influence of ethanol extract from sappan wood on blood glucose level of white rats. The study of the blood glucose level in rats was carried out by using glucose tolerance method. It was measured by Refloluxs (Accutrend GC) with Chloropropamide 50 mg/200 g BW (Body weight) as positive control. The ethanol extracts were used in various concentrations 10, 20, 30, 40 and 50 mg/200 g BW per-oral and was observed every  hour,  beginning one hour before to 7 hours after the extract being administered. The results showed that treatment of ethanol extract of sappan wood by administer doses gave remarkable effect on the blood glucose level in white rat. It reduced the glucose level in the blood compared to the negative and positive control. Treatment of dose 30 mg/200 g BW gave similar effect to positive controls, while a dose of 50 mg/200 g BW gave lower blood glucose level (93 mg/dl) than the positive controls.
BIOLOGICAL ACTIVITIES AFFORDED BY THE EXTRACT FROM RARU BARK TO INHIBIT ACTION OF ALPHA- GLUCOSIDASE ENZYMES Pasaribu, Gunawan; Syafii, Wasrin; Darusman, Latifah K.
Indonesian Journal of Forestry Research Vol 8, No 1 (2011): Journal of Forestry Research
Publisher : Secretariat of Forestry Research and Development Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/ijfr.2011.8.1.32-49

Abstract

Raru (Shoreabalanocarpoides Sym) signifies one of the tree species that grows widespread in Sumatra Island.  Its bark portion is commonly used by local villagers as additional ingredient mixed to nira (sugar palm juice).  This addition is intended to make the juice more durable and also to enrich its taste after the juice is previously fermented to become traditional toddy beverage or the so-call “tuak”.  Local villagers believe that raru bark can reduce the level of blood sugar. As the relevance, the research was conducted to confirm that the extract from raru bark could afford its biological activities to inhibit alpha-glucosidase enzyme through its characterization, quantification, and isolation of its boactive compound. The extraction was performed using two methods (i.e.reflux and maceration techniques). Result revealed that the bark extract obtained from both techniques contained polyphenol compounds: flavonoid, saponin and tannin. Further, raru-bark extract from the reflux and maceration techniques could inhibit the action of alpha glucosidase enzymes on carbohydrate substrate ( i.e. p -nitrophenil-α-D-glucopyranose), at respectively 90.67% and 97.33%. Meanwhile, the inhibition activities afforded by the patented drug as a control (i.e. glucobay) equaled to 97.05%.  Assesment using UV-VIS spectroscopy, showed that the maximum spectrum of bioactive compound in the extract was at the wave length of 288.6 nm. Scrutiny using FTIR spectroscopy could identif y the presence of aromatic groups in the compound, containing -OH, C-H, C=C, C-O and C-H bond types. Analysis using GC-MS exhibited that the compound had molecular weight of 390 with molecular structure as C20H22O8. Ultimately, data analysis scrutiny with the aid of NMR judged the most plausible compound as bioactive was 4-Glucosyl-3, 4’, 5-trihydroxystilbene.
KERAGAMAN KOMPONEN KIMIA GAHARU PADA KELAS SUPER DAN KEMEDANGAN Pasaribu, Gunawan; Waluyo, Totok Kartono; Pari, Gustan
Jurnal Penelitian Hasil Hutan Vol 33, No 3 (2015): Jurnal Penelitian Hasil Hutan
Publisher : Pusat Penelitian dan Pengembangan Hasil Hutan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/jphh.2015.33.3.247-252

Abstract

Tulisan ini menyajikan kadar resin dan komposisi senyawa kimia dari beberapa kualitas gaharu menggunakan kromatografi gas spektrometri massa.  Kualitas gaharu yang diuji adalah kelas super dan kemedangan yang berasal dari Bangka, Papua dan Asosiasi Pengusaha Eksportir Gaharu Indonesia (Asgarin). Hasil penelitian menunjukkan rendemen resin gaharu lebih tinggi pada kelas kualitas super daripada kelas kemedangan. Gaharu berkadar resin tinggi dianggap sebagai berkualitas tinggi (super), dan komposisi kimianya didominasi oleh chromone dan gamma gurjunene. Sebaliknya gaharu berkualitas rendah (kemedangan) berkomposisi kimia 2,5 furandione, 3-dodecenyl dan agarospirol. Komponen kimia gaharu kelas super mengandung lebih banyak senyawa kelompok sesquiterpena dibanding kelas kemedangan. Senyawa sesquiterpene dan chromone berindikasi kuat menyebabkan aroma harum pada gaharu. Kualitas gaharu pada kelas yang sama menunjukkan rendemen resin dan komposisi kimia yang berbeda dari tiga lokasi yang diteliti.
AKTIVITAS ANTIJAMUR, ANTIBAKTERI DAN PENYEMBUHAN LUKA EKSTRAK RESIN JERNANG Waluyo, Totok Kartono; Pasaribu, Gunawan
Jurnal Penelitian Hasil Hutan Vol 33, No 4 (2015): Jurnal Penelitian Hasil Hutan
Publisher : Pusat Penelitian dan Pengembangan Hasil Hutan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20886/jphh.2015.33.4.377-385

Abstract

Jernang atau dragon’s blood merupakan salah satu produk hasil hutan bukan kayu  yang bernilai tinggi berasal dari hutan Indonesia.  Jernang adalah resin berwarna merah hasil sekresi buah rotan dan pemanfaatannya masih secara tradisional.  Tujuan dari penelitian ini adalah untuk menentukan kemampuan jernang sebagai antibakteri dan antijamur terhadap bakteri (Basillus subtilis dan Staphylococcus aureus) dan jamur (Candida albicans dan Aspergillus flavus). Kemampuan antibakteri dan antijamur ditentukan berdasarkan uji penyembuhan luka secara in vivo terhadap kelinci. Hasil penelitian menunjukkan bahwa secara umum jernang bersifat antibakteri dan antijamur. Ekstrak etil asetat jernang efektif sebagai antimikroba untuk penyembuh luka.
Co-Authors Efrida Basri Erik Dahlian Gusmailina Gusmailina Gustan Pari Jasni Jasni Latifah K. Darusman Ratih Damayanti Saefudin Saefudin Santiyo Wibowo Sofnie Sofnie Sri Komarayati Titiek Setyawati Totok K Waluyo Totok K. Waluyo, Totok K. Totok Kartono Waluyo, Totok Kartono Wasrin Syafii dan Kurnia Sofyan Gustan Pari Buchari Zulnely Zulnely