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Muji Rahayu
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Analisis Antalgin dalam Jamu Pegal Linu yang Dijual di Pasar Beringharjo Yogyakarta Siti Fatimah; Muji Rahayu; Debi Firma Indari
Journal of Health (JoH) Vol 4 No 1 (2017): Journal of Health - January 2017
Publisher : LPPM STIKES Guna Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.342 KB) | DOI: 10.30590/vol4-no1-p29-34

Abstract

Background: Traditional medicine is an ingredient or ingredients in the form of plant material, animal material, mineral materials, preparation essence (galenic), or mixtures of these materials that have historically been used for treatment, and can be applied according to the prevailing norms in society. Traditional medicine is often chosen as a remedy for health care is herbal, because herbal medicine is a health drink. Chemicals drugs were added by the makers of herbal medicine with the intent may be to increase the efficacy of herbal medicine and herbal medicine provide more instant effect, it is becoming a source of danger herbs. BPOM many find herbs aching pains who defiled chemical medicines like phenylbutazone, methampyrone, diclofenac sodium, piroxicam, paracetamol, prednisone, or dexamethasone. Chemicals a drug it is set in PERMENKES 007 of 2012. Methods: This research is to describe the whether or not of chemicals in the antalgin sold in the Beringharjo traditional market Yogyakarta. The method used to test the lab using thin layer chromatography. Research data presented in terms of percent. Results: Research is obtained value Rf sample 0.63 until 0.8 one sampel having the value Rf and fluorescence equal to standard methampyrone. Value Rf standard methampyrone 0,78 and red purple fluorescence. Conclusion: There are methampyrone in herbal medicine aching pains sold in the Beringharjo traditional market to a presentation positive results as many 8.3% and negative results 91.7%.
Kajian Aktivitas Antioksidan Kacang Gude (Cajanus cajan) dan Pengaruhnya Terhadap Aktivitas Enzim Hati Tikus Yang diinduksi Karbon Tetraklorida Roosmarinto Roosmarinto; Muji Rahayu
Jurnal Teknologi Kesehatan (Journal of Health Technology) Vol. 12 No. 2 (2016): September
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1157.813 KB)

Abstract

Legumes bean is a plant that is rich in compounds called polyphenols, especially flavonoids. Pigeon pea is a legume species that has purple-black skin, contains various compounds, among others, polyphenols, anthocyanins, and flavonoids. Polyphenol, anthocyanins, and flavonoids compounds have an antioxidant activity of endogenous antioxidants which can help to fend off free radicals that occur in the body. The antioxidant activity of pigeon pea (Cajanus cajan) in vitro has measured using DPPH method and obtained results of IC50 value of 70.32 mg/ml. Pigeon pea beans contain anthocyanin compounds of 208.307 mg / 100 g. Measurement of antioxidant activity pigeon pea in vivo was performed by animal model white rats Wistar male as many as 25 animals that were divided into 5 groups. Each experimental group consisted of 5 mice, the group N as a normal control group, the group S as a pain control, the group G1, G2, and G4 were given bean powder pigeon pea respectively 100, 200 and 400 mg / bwt with sonde, for 14 days , S group, G1, G2 and G4 induced by carbon tetrachloride with intraperitoneal administration. After 24 hours, the blood of all rats was taken through vena orbitalis and then the activity of AST, ALT and GGT enzymes and levels of malondialdehyde (MDA) were determined. The result of this study showed inhibition of the increase in the activity of AST, ALT and GGT enzymes and MDA levels in rats fed with powdered pigeon pea. From these results, it can be concluded that pigeon pea beans have antioxidant activity which is capable of preventing damage to liver cells and lipid peroxidation. A result of this study showed inhibition of the increase in the activity of enzymes AST, ALT and GGT and MDA levels in rats fed powdered pigeon pea. From these results, it can be concluded that pigeonpea beans have antioxidant activity which can prevent a damage in Hepar cells and lipid peroxidase.
Co-Authors Debi Firma Indari Roosmarinto Roosmarinto Siti Fatimah