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All Journal Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School
Emil Azlin
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Health Professions Medicine & Pharmacology

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Comparison of blood glucose levels in breastfed vs. formula-fed low birth weight infants Eli Tua Pangaribuan; Bugis M. Lubis; Pertin Sianturi; Emil Azlin; Guslihan D. Tjipta
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.771 KB) | DOI: 10.14238/pi49.1.2009.15-9

Abstract

Background  Low  birth weight infants are defined  as  babies withbirth weight less  than  2500 grams.  Low  birth weight infants tendto suffer from hypoglycemia compared to full term infants.  Theincidence  of  hypoglycemia in newborns varies between 1.3 and  3per 1000 live births. Blood glucose levels in formula-fed infantsare lower  than  those in breastfed infants.Objective  To  compare blood glucose levels in breastfed  andformula-fed low birth weight infants.Methods  A cross sectional study was conducted between February2007  and  June 2007  at  Pirngadi and H. Adam Malik GeneralHospital in Medan,  North  Sumatra, Indonesia. All low birthweight babies were classified into two groups: the breastfed  andformula-fed. Each group consisted  of  32 infants. Capillary bloodwas collected using heel pricks  at  1,  48,  and  72 hours after birth,and plasma glucose was evaluated using the Glucotrend2 bloodglucose test.Results  The  breastfed low birth weight infants had significantlyhigher blood glucose levels (P=0.002)  than  formula-fed low birthweight infants. Mode of delivery  was  related to blood glucose level.Infant delivered  by  caesarean section had significantly differentblood glucose levels  at  1 hour  (P=0.005)  and  72  hours afterbirth (P=0.027).  The  full-term infants had significantly higherblood glucose level (P=0.007)  than  the small for gestational ageinfants.Conclusions  Generally,  low  birth weight infants have hypoglycemiaafter first hour  of  delivery. Breastfed low birth weight infants havehigher blood glucose levels  than  formula-fed low birth weightinfants.
Comparison of blood glucose level between breast--fed and formula--fed term babies Omar Sazali Aldy; Bugis M Lubis; Pertin Sianturi; Emil Azlin; Guslihan D. Tjipta
Paediatrica Indonesiana Vol 48 No 4 (2008): July 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi48.4.2008.209-13

Abstract

Background Hypoglycemia is common in newborns in the firstfew hours after birth. This may also occur in term babies. Dataof hypoglycemia in breastfed and formula-fed infants have beenlimited.Objective To compare blood glucose levels between breast-fed andformula-fed healthy term babies at 1, 24 and 48 hours of life.Methods A cross sectional study was performed on 32 neonatesbetween January and March 2007 in the Dr. Pirngadi Hospital.The subjects was classified into two groups, the breastfed andformula-fed groups. Blood glucose level was examined at 1, 24,and 48 hours after birth and level ofless than 2.6 mmol/1 definedthe presence of hypoglycemia.Results There was statistically significant difference in meanblood glucose level at 1 hour of life between breastfed [59.25(SD 3.38) mg/dl] and formula-fed infants [55.96 (SD 8.60) mg/dl], (P=0.049), while no significant difference was found after24 hours of life, i.e., 62.59 (SD 3.57) mg/dl vs. 61.21 (SD 6.87)mg/dl, P=0.319 and also after 48 hours of life, i.e., 67.34 (SD5.18) mg/dl vs. 66.75 (SD 7.76) mg/dl, P=0.720.Conclusion The blood glucose level at one hour after birth wassignificantly different in breastfed compared to formula-fed infants,while no statistically significant difference was found at 24 hoursand 48 hours after birth. The mean blood glucose at 24 hours oflife was lower than that of 48 hours after birth
Comparison of the effect of oral multiple dose with single intramuscular vitamin K1 administration on prothrombin time in term baby Nancy Ervani; Bugis M. Lubis; Emil Azlin; Guslihan D. Tjipta; Lily Emsyah
Paediatrica Indonesiana Vol 49 No 5 (2009): September 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.26 KB) | DOI: 10.14238/pi49.5.2009.281-5

Abstract

Background Vitamin K deficiency can cause bleeding disorders inhealthy breastfed infants. The efficacy of newborn intramuscularvitamin K prophylaxis for the prevention of this bleeding problemhas been well established, but this is an invasive procedure. Oralvitamin K prophylaxis is more effective, less expensive, and lesstraumatic than intramuscular administration.Objective To compare prothrombin time (PT) after theadministration of oral multiple dose vitamin K1 with that afteran intramuscular preparation.Methods Infants were randomised at birth into the intramuscular(IM) group (1 mg vitamin K1) and the oral group (2 mg given atbirth and repeated at day 3). PT was monitored before and afterthe administration of vitamin K1.Results Thirty six of 70 infants received oral vitamin K1. MeanPT (SO) before vitamin K1 administration was 36.34 (SO 20.03)seconds in oral group and 31.96 (SO 25.51) seconds in IM group, PT changes after vitamin K1 administration were 16.29 (SO 15.46) seconds in oral group and 11.58 (SO 10.62) seconds in IM group, it did not differ significantly (P=0.203).Conclusion Prothrombin time changes are not significantlydifferent between oral vitamin K1 and IM group.
The effectiveness of chloroquine compared to Fansidar in treating falciparum malaria Emil Azlin; Ichwan HH Batubara; Wisman Dalimunte; Charles Siregar; Bidasari Lubis; Munar Lubis; Syahril Pasaribu
Paediatrica Indonesiana Vol 44 No 1 (2004): January 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.919 KB) | DOI: 10.14238/pi44.1.2004.17-20

Abstract

Background The most difficult problem in eradicating malaria isthe resistance of P. falciparum to drugs. Mandailing Natal has thehighest malaria incidence in North Sumatera.Objective This study aimed to investigate the efficacy of chloro-quine and Fansidar in treating falciparum malaria.Methods A randomized double-blind study was done from April toMay 2001. Eighty-three patients with acute uncomplicated P.falciparum malaria infection were randomized into two groups.Group I (35 patients) received chloroquine and group II (48 pa-tients) received Fansidar. Blood examinations were performed onthe 1 st , 2 nd , 7 th , and 28 th days.Results The resistance of P. falciparum to drugs in the chloro-quine group were found in 10 patients with R II and 1 patients withR III, while in the Fansidar group, there were 14 patients with R II.Conclusion The efficacy of chloroquine and Fansidar in treatingfalciparum malaria was not significantly different
Pengaruh domperidon terhadap produksi ASI pada ibu yang melahirkan bayi premature Tengku Ellya Fazilla; Guslihan Dasa Tjipta; Emil Azlin; Pertin Sianturi
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Mother who gave birth to premature babies often have difficulty getting adequate milk production. Various attempts to increase milk production have been made, including pharmacological interventions. One of the drugs that can be used is domperidone. Domperidone is a peripheral dopamine receptor antagonist, works by blocking the inhibitory effects of dopamine-mediated prolactin secretion, thereby increasing milk production. Three randomized double-blind study showed that domperidon can increase milk production without causing any side effects to the mother and baby.Keywords : domperidone; premature; breastfed
Terapi antibiotika empiris pada neonatus Muchtar Kusuma Hayatullah; Guslihan Dasa Tjipta; Pertin Sianturi; Emil Azlin; Bugis Mardina Lubis; Syamsidah dr; Fera Wahyuni
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.074 KB)

Abstract

Neonatal sepsis is a clinical syndrome with symptoms of systemic infection and followed by bacteremia in the first month of life. Antibotic initial therapy empirically is often given concomittantly awaiting the results of blood cultures in neonates with suspected sepsis. The recommended initial treatment in general is a combination of ampicillin and aminoglycoside (gentamicin). Alternative to aminoglycosides is the third-generation cephalosporins (eg cefotaxime). This regimen was found safe and effective by appropriate duration of therapy. This therapy should be evaluated every 48 hours with a lingering risk of therapy associated with increased risk of necrotizing enterocolitis and death.Keyword : antibotic initial, Neonatal sepsis
Osteopenia prematuritas dan upaya pencegahannya Febriyanti Mobilina; Guslihan Dasa Tjipta; Emil Azlin; Pertin Sianturi; Bugis Mardina Lubis; Beby Syofiani Hasibuan
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 3 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Osteopenia of prematurity is a common problem encountered in preterm infants or infant with low birth weight. This is characterized by decreased bone mineral content due to inadequat nutritional intake and biochemical factors. This condition can make metabolic disorders in pathological bone fractures even in newborns. Incidence of osteopenia in low birth weight infants in 30%, whereas in infants less than 1000 g of about 55%, and infants less than 1500 g as much as 23%. For preterm infants, the features commonly associated with fracture are delivery at less than 28 weeks of gestation. Metabolic bone disease is often not detected at early stage and became known after appearing obvious abnormalities in the bone or in radiologic examination. Therefore, it is necessary to screening with serum biochemical examination of blood in serum levels of calcium, phosphate and alkaline phosphatase. In addition, it was important to intake of calcium and phosphorus are sufficient for bone mineralization. Key word : osteopenia of prematurity, preterm, calcium, calcium
Co-Authors Bidasari Lubis Bugis M Lubis Bugis M. Lubis Bugis Mardina Lubis Charles Siregar Eli Tua Pangaribuan Febriyanti Mobilina Fera Wahyuni Guslihan D. Tjipta Guslihan Dasa Tjipta Ichwan HH Batubara Lily Emsyah Muchtar Kusuma Hayatullah Munar Lubis Nancy Ervani Omar Sazali Aldy Pertin Sianturi Syahril Pasaribu Syamsidah dr Syofiani Hasibuan, Beby Tengku Ellya Fazilla Wisman Dalimunte