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All Journal HAYATI Journal of Biosciences Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Pengajaran MIPA Jurnal Pendidikan Indonesia Formica Education Online Jurnal Pendidikan Biologi Indonesia These proceedings represent the work of researchers participating in The International Conference on Elementary Education (ICEE) which is being hosted by the Elementary Education Study Programme School of Postgraduate Studies, Universitas Pendidikan Proceeding Biology Education Conference
Didik Priyandoko
Department Of Biology Education, School Of Post Graduates, Universitas Pendidikan Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Education Environmental Science Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences

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Journal : HAYATI Journal of Biosciences

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Molecular Phylogenetic Screening of Withania somnifera Relative From Indonesia Based on Internal Transcribed Spacer Region Topik Hidayati; Didik Priyandoko; Putri Yunitha Wardiny; Dina Karina Islami
HAYATI Journal of Biosciences Vol. 23 No. 2 (2016): April 2016
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (562.581 KB) | DOI: 10.4308/hjb.23.2.92

Abstract

Withania somnifera (family Solanaceae), known commonly as Ashwaganda, is one of the important medicinal plants, and recent studies reported that Withanone, one of the chemical components in this plant, has ability to kill cancer cell. Because of endemic state of this plant to South Asia, exploring plant species under the same family which grow well in Indonesia has been of interest. The purpose of this study was to screen the Indonesian plant which has strong phylogenetic relationship with Ashwaganda. Thus, phylogenetic analysis using DNA sequences of internal transcribed spacer (ITS) region was conducted. Thus, 19 species of Solanaceae and two species of Convolvulaceae as outgroup were examined. Five ITS regions of Ashwaganda retrieved from GenBank were included in the phylogenetic analysis. Parsimony analysis showed that Indonesia Solanaceae comprises seven groups which is consistent with the global Solanaceae relationship as previously reported. Furthermore, our study revealed that two species, Physalis angulata and Physalis peruviana, are relative to W. somnifera. Morphologically, they share characters of flower and fruit. This result indicated that these two species are potential to have similar chemical properties as Ashwaganda, thus we can have new variants of Withanone originated from Indonesia with similar effect.
Co-Authors Adi Rahmat Anisa Noor Aulia DADANG MACHMUDIN Deocaris, Custer C. Dina Karina Islami Fransisca Sudargo Fransisca Sudargo Gina Angelina Handayanie, Yunni Kaul, Sunil C. Mamat Arohman Nashi Widodo Nia Nurdiani Nuryani Rustaman Prima Mutia Sari Putri Yunitha Wardiny Sa'diatul Fuadiyah Saefudin Saefudin Saefudin Saefudin Sari, Prima Mutia Sholihah, Uswatun Topik Hidayat Wadhwa, Renu Wawan Setiawan Wawan Setiawan Yusuf Hilmi Adisendjaja