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Irsad Andi Arso
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Medicine & Pharmacology

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Diagnostic Performance Addition of Abnormal P Wave Dispersion on Moderate Risk Duke Treadmill Score Criteria in Detecting Severe Stenosis of Coronary Arteries in Stable Angina Pectoris Patients Widodo Darmo Sentono; Erika Maharani; Irsad Andi Arso
ACI (Acta Cardiologia Indonesiana) Vol 1, No 2 (2015)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.17810

Abstract

Background: Moderate risk Duke treadmill score (DTS) in threadmill test (TMT), needs additional diagnostic tool to increase its sensitivity of detecting severe coronary artery stenosis in patients with stable angina pectoris. A P wave dispersion (PWD) during TMT currently has a significant relationship with DTS value and can increase the sensitivity in identifying an ischemia. This studyaimed to investigate whether the addition of PWD in moderate risk DTS can improve the prediction of the severity of coronary artery stenosis in patients with stable angina pectoris. Methods: This study is a diagnostic test with cross-sectional design. The subjects were patients who had undergone TMT and coronary angiography at the Dr. Sardjito General Hospital Yogyakarta. The outcomes were sensitivity and specifi city of abnormal PWD in moderate risk DTS patients for predicting the severe stenosis in those with stable angina pectoris as compared with moderate risk DTS and normal PWD.Results: The additional of PWD at moderate risk DTS on 64 subjects had a sensitivity of 86.7%, a specifi city of 44.1%, a positive predictive value of 57.8%, a negative predictive value of 79.0%, a positive likelihood ratio of 1.6, a negative likelihood ratio of 0.3 and a prevalence of 46.9%, witha prediction accuracy of 64.1%. Conclusion: The additional of abnormal PWD in moderate risk DTS had a sensitivity of 86.7% and a specificity of 44.1% for severe coronary artery stenosis in patients with angina pectoris.Keywords: P wave dispersion, moderate risk Duke treadmill score, severe coronary stenosis.
Common Atrium in Ellis Van-Creveld Syndrome Kartika Apshanti; Irsad Andi Arso; Bambang Irawan
ACI (Acta Cardiologia Indonesiana) Vol 1, No 2 (2015)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.17814

Abstract

Single atrium is a complete absence of atrial septum.1 It is often found in Ellis-van Creveld Syndrome. Ellis-van Creveld Syndrome is a chondral and ectodermal dysplasia that is characterized by short ribs, polydactyly, growth retardation and also ectodermal and heart defects. We report a male, 18 years old who came with worsening of dyspnea. At physical examination we found short stature, polydactyly, cardiomegaly, severe scoliosis, genu valgum and nail hypoplasia. Transthoracic echocardiography showed the complete absence of atrial septum with signs of pulmonary hypertension.Keywords: common atrium, Ellis-van Creveld Syndrome, polydactyly
Association Between Coronary Artery Lesion Severity and Erectile Dysfunction in Stable Coronary Heart Disease Patients Arif Bowo Kurniawan; Irsad Andi Arso; Nahar Taufiq
ACI (Acta Cardiologia Indonesiana) Vol 2, No 1 (2016)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/aci.17816

Abstract

Background: Atherosclerosis is the underlying process of coronary heart disease. Atherosclerosis is preceded by endothelial dysfunction caused by systemic mechanical and chemical stressors that may occur throughout the blood vessels. Recent studies have found the link incidence of atherosclerosis in the coronary arteries and other arteries as well. Erectile dysfunction (ED) is a clinical manifestation might be caused by atherosclerosis in iliac or pudendal artery. Previous studies have established the relationship between coronary artery involvement and the incidence of ED, but the odds of risk has not been well established. Methods: This was an age matched-paired case-control study. Erectile dysfunction in CHD patients who had undergone coronary angiography was checked by IIEF - 5 questionnaire. The severity of coronary artery lesion was assessed with a Syntax score from coronary angiography results. Moreover these results were assessed by a single experienced observer, blind method and were shown consistency test. Then, the risk of coronary artery lesion severity of the ED was analyzed by chi square test using SPSS version 20. Result: There were 86 subjects consist of 57 subjects in the case group and 29 subjects in thecontrol group. Stable CHD patients with high Syntax scores had 2.75 times risk for development of ED compare with low Syntax scores patients (OR : 2.75, 95 % CI : 1.08 to 6.95, p = 0.03). The severity of coronary artery lesions assessed with Syntax scores were not statistically signifi cant as an independent factor as the incidence of ED. Conclusion: Stable CHD patients with higher severity of lesions in coronary artery have a higher risk of erectile dysfunction than patients with lower severity of the lesion but was not statistically significant as an independent factor on the incidence of ED.Keywords: Severity of coronary artery lesions, erectile dysfunction, stable coronary heart disease
Co-Authors Arif Bowo Kurniawan Erika Maharani Kartika Apshanti Maemonah, Maemonah Nahar Taufiq Widodo Darmo Sentono