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All Journal Jurnal Syntax Fusion : Jurnal Nasional Indonesia KESANS : International Journal of Health and Science
Ni Putu Yunandari
Universitas Mataram
Chemistry Education Engineering Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Physics Public Health Social Sciences

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Non-Immune Hemolytic Anemia (Hemoglobinopathy) Ni Putu Yunandari
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 3 (2021): KESANS : International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i3.27

Abstract

Hemoglobinopathy is an autosomal recessive disorder that is classified into 2 major groups, namely thalassemia syndromes and structural variants of the hemoglobin chain. Thalassemia is a group of genetic disorders caused by decreased speed of chain synthesis or. The second group, structural abnormalities in the hemoglobin chain, often causes a condition called sickle cell (sickle cell anemia), this structural abnormality occurs due to the substitution of adenine by thymine which causes the conversion of the amino acid glutamate to valine. 7% of the world's population are carriers of hemoglobinopathies. This type of research is literature research or literature review. Based on data from the Indonesian Thalassemia Foundation (YTI) in 2008-2017, 5.8% of thalassemia carriers were found from 12,038 people examined, and 28.62% of 4,137 people according to the results of family screening. thalassemia in 2009-2017. The prognosis of thalassemia disease depends on medication adherence and the type of thalassemia suffered. Death in patients with sickle cell anemia is usually due to co-morbidities such as renal and other organ failure. Early and adequate symptom management can improve the prognosis. This disorder is autosomal recessive which is classified into 2 major groups, namely thalassemia syndrome and structural variants of hemoglobin chains that often produce sickle cell shape
Artritis Psoriatika Faris Rizki Ardhan; Muhammad Akbar Hanardi; Dhila Thasliyah; Visakha Vidyadevi Wiguna; Ni Putu Yunandari
Jurnal Syntax Fusion Vol 1 No 12 (2021): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : Rifa' Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v1i12.118

Abstract

To know the risk factors, pharmacological treatment and prevention of psoriatic arthritis. Psoriatic arthritis is a chronic musculoskeletal disease associated with psoriasis. at least 5% of psoriasis patients develop psoriatic arthritis. Globally, the incidence of PsA reaches 133 per 100,000 patient subjects. The annual incidence of PsA is about 2.7 cases per 100 people diagnosed with psoriasis. In Asia, PsA cases increased from 2000 to 2013 with a prevalence (per 100,000 population) of 11.12 to 37.75. Based on a study at Sanglah Hospital Bali found PsA patients as much as 6.3% of psoriasis patients. PsA patients may have clinical features such as peripheral arthritis, enthesitis, dactylitis, skin, nail, and axial involvement. Risk factors for psoriatic arthritis include obesity, physical trauma, smoking, location of psoriasis in the body, education level and genetic factors. Pharmacological treatment of PsA based on the latest guidelines from EULAR 2019 and ACR recommendations. These two guidelines discuss pharmacological treatment based on the patient's clinical picture. The goal of pharmacological therapy is to improve the patient's quality of life by improving symptomatic complaints and preventing structural damage. As a prevention, PsA maintains an ideal body weight, reduces cigarette consumption, and performs detection as an early detection.
Pitiriasis Rosea: Manifestasi Klinis Dan Tatalaksana Muhammad Akbar Hanardi; Faris Rizki Ardhan; Visakha Vidyadevi Wiguna; Dhila Thasliyah; Ni Putu Yunandari
Jurnal Syntax Fusion Vol 2 No 01 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : Rifa' Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i01.131

Abstract

Pitiriasis rosea (PR) is a papulosquamous disorder with appearance of multiple, discrete patchesof skin rash in a distinctive pattern over the trunk and limbs. Epidemiologic studies on PR in Africa showed 2,2% to 4,8% dermatologist patient have a PR. The incidence is 170 cases per 100,000 persons per year and It typically affects persons 10 to 35 years of age. The clinical presentation of PR can be a single larger lesion, measuring about 2 to 10 centimetres, usually precedes the widespread rash for up to two weeks. This initial lesion, also known as the 'herald patch', most commonly appears on the trunk, and then the secondary eruption occurs. Lesions are similar to the herald patch but smaller. Their distribution commonly follows the skin cleavage lines in what is referred to as the 'Christmas tree pattern'. The risk factor of PR such as COVID-19 infection, herpes virus reactivation, environmental factors, and pregnancy factors. Treatment is aimed at controlling symptoms and consists of antihistamines, antibiotics or corticosteroids. In some cases, acyclovir can be used to treat symptoms and reduce the length of disease. Ultraviolet phototherapy can also be considered for severe cases
Co-Authors Dhila Thasliyah Faris Rizki Ardhan Muhammad Akbar Hanardi Visakha Vidyadevi Wiguna