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All Journal Berkala Ilmiah Mahasiswa Farmasi
Lika Ginanti Febriana
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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REVIEW ARTIKEL : TANAMAN YANG MEMILIKI AKTIVITAS ANTI-ULSER DI ASIA Nabila Putri Azzahra; Kirka Dwi Apriali1; Lika Ginanti Febriana
Berkala Ilmiah Mahasiswa Farmasi Indonesia Vol 8 No 2 (2021): Berkala Ilmiah Mahasiswa Farmasi Indonesia (BIMFI)
Publisher : Ikatan Senat Mahasiswa Farmasi Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48177/bimfi.v8i2.80

Abstract

Introduction : Herbal medicines have high potential in treating various diseases including gastric ulcers because they are considered safer and more comfortable. Ulcers or gastric ulcers are disorders of the stomach due to an imbalance of aggressive factors (gastric acid secretion, pepsin, and Helicobacter pylori infection) with defensive factors (prostaglandins, mucus, bicarbonate, mucosal blood flow, and intrinsic epithelial cells). Methods : The method used is a literature review study conducted by searching for keywords such as peptic ulcer disease, herbal plants, anti-stomach ulcers, and others in databases such as PubMed and Google Scholar. Results : From the literature review, 29 medicinal plants in Asia have a potential anti-ulcer activity that can prevent and help treat gastric ulcers. The table of medicinal plants is arranged based on the phytochemical analysis, the part used, and the country where the plant originates. Conclusion : Plants that have the potential to prevent and help heal gastric ulcers that are spread in Asia include phytochemicals containing flavonoids, tannins, polyphenols, alkaloids, glycosides, terpenoids, saponins with various mechanisms, namely gastroprotective, antioxidant, anti-inflammatory, anti-secretory, anti-Helicobacter. pylori, and astringents.
Tinjauan Pustaka: Karakteristik Dan Respon Antibodi Vanksin Dengan Sediaan Microneedle Patch Lika Ginanti Febriana
Berkala Ilmiah Mahasiswa Farmasi Indonesia Vol 9 No 2 (2022): Berkala Ilmiah Mahasiswa Farmasi Indonesia (BIMFI)
Publisher : Ikatan Senat Mahasiswa Farmasi Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48177/bimfi.v9i2.99

Abstract

Introduction: Vaccination is one of the greatest medical advances of modern preventive medicine. Vaccination is the most effective way to control the incidence of infectious diseases. However, the current vaccination approach faces a number of challenges that impact vaccination compliance. Most vaccines given by intramuscular (IM) or subcutaneous (SC) injection cause pain and discomfort, in most cases, leading to poor adherence due to needle phobia. The development of microneedle patch technology has been applied to various types of vaccines. Methods: The research method used is literature review. The literature sources used in this study were searched through the PubMed® and Google Scholar databases with the keywords microneedle vaccine, vaccine patch, and microneedle patch vaccine. Found 20 articles that can be used in the literature review Result: The results of research on the microneedle patch from various types of vaccines need to be studied to determine the effectiveness of the vaccine in the form of a microneedle patch. Various aspects such as the type of microneedle patch, needle height, and antibody response to vaccine preparations in the form of a microneedle patch can be indicators to assess the potential of a microneedle patch. Conclusion: Various aspects such as the type of microneedle patch, needle height, and antibody response to vaccine preparations in the form of a microneedle patch can be used as indicators to assess the potential of a microneedle patch. There are four types of microneedle, namely Solid Microneedle, Coated Microneedle, Dissolving Microneedle, and Hollow Microneedle. To penetrate the skin, the microneedle has a pointed tip with a length of 150-1500 m, a width of 50–250 m, and a tip thickness of 1–25 m. Microneedle patch can induce antibody formation to be faster.. Keywords: Microneedle Patch, Vaccine, Vaccination
Co-Authors Kirka Dwi Apriali1 Nabila Putri Azzahra