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FORMULATION OF DRAWINGS (DRYMOGLOSSUM PILOSELLOIDES L. PRESL) ETHANOL EXTRACT OF ACNE GEL ON THE GROWTH OF THE BACTERIA PROPIONIBACTERIUM ACNES Zola Efa Harnis; Nina Irmayanti Harahap; Rika Puspita Sari; Sarviana Lubis
Jurnal EduHealth Vol. 12 No. 02 (2022): : March, Jurnal EduHealth
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (534.18 KB)

Dragon scales (Drymoglossum piloselloides L. Presl) is a plant that has antibacterial activity against the bacteria Propionibacterium acnes and Staphylococus aureus, Bacillus subtilis, Escherichia coli, and Streptococcus pneumonia. The content of compounds that act as antibacterial are saponins, polyphenols, essential oils, sterols / triterpenes, phenols, flavanoids, sugars and tannins. This study aims to make a formula of dragon scales ethanol extract gel against the growth of propionibacterium acnes bacteria. The method used in this study was experimental laboratory. The formulation of dragon scales ethanol extract gel is made with a concentration variation of 5%, 10%, 15%. Antibacterial activity test is carried out with diffusion agar.

FORMULATION OF HAND SANITIZER GEL PREPARATION COMBINATION OF NEMBA LEAF (AZADIRACHTAINDICAA.JUSS) ETHANOL EXTRACT OF AND EXTRACT OF ALOE VERA (ALOE VERA)AGAINS STAPYLOCOCCUCAUREUS BACTERIA Rika Puspita Sari; Zola Efa Harnis Harnis; Nina Irmayanti Harahap; Rissa Dewi Ramadhani
Jurnal EduHealth Vol. 12 No. 02 (2022): : March, Jurnal EduHealth
Publisher : Sean Institute

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The use of hand antiseptics in the form of gel preparations which are more popular with the namepreparations hand sanitizer usually contain antiseptics in the form of synthetic chemicals which are relatively expensive and often cause skin health problems, such as dry skin. The leaves of the neem plant and aloe vera gel have been shown to be able to treat several diseases, one of which is being able to be a companion drug for antibacterial treatment. The method used in this research is experimental method because it is intended to determine the effect or relationship between the independent variables called treatment factors, namely thegel formulation Hand Sanitizer from a combination of neem leaves and aloe vera gel with concentrations of 5%, 10%, and 15%, with the dependent variable called the observation factor, namely the test. Organoleptic, pH, homogeneity, dispersion test, irritation test and antibacterial activity tes. The results obtained from this study are that neem leaf ethanol extract and aloe vera gel can be formulated intopreparations hand sanitizer gelwith concentrations of 5%, 10% and 15%, with homogeneous preparations, pH around 6.68-7.03, with dispersion ranges from 4.4cm - 5.5 cm, and stable at 4 weeks of storage.. Results preparations hand sanitizers containing ethanol extract of neem leaves 15% provides a strong barrier against Staphylococcus aureus was 13.80 ± 0.29 mm.

EFEK PENYEMBUHAN LUKA BAKAR GEL KOMBINASI EKSTRAK ETANOL DAUN AFRIKA (Vernonia Amygdalina) DAN EKSTRAKETANOLDAUNBANGUN–BANGUN(ColeusamboinicusLour) Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 3 No 1 (2020): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i1.318

african leaves ( Vernonia Amygdalina )and wake-up leaves (Coleus amboinicus Lour)are plants traditional plants that are used as medicine. Leaves african which is contain flavonoid, saponin, tanin and leaves wake up which is contain flavonoid, tanin, saponin and steroid. This study to find aims out as effect healing of burns.Method : Sample in this study was african leaves and wake-up leaves which were taken purposively without comparing sampel from other regions, then extrated by maceration using ethanol 96 %. Result : Testing of rhe healing effects of burns can be divided in five treatment, positive group using biolacenton , negatif group using basis gel and the last group using the extract ethanol gel EEDA and EEDB concentrations of 4%+2,5%,8%+5%,16%+10%. Given burns to the back of rabbits length with of 2cm, and the gel is applied twice a day for 11 day and diameter measured of the wound. Conclusion : The combination of EEDA and EEDA the ethanol extract the concentration of 16% + 10% was the effective control for healing burns. When compared bioplacenton gel as a healing wound in rabbit.

FORMULASI DAN UJI STABILITAS LOTION SARI BUAH TOMAT (licopersicon esculentum mill) KOMBINASI KUNYIT (Curcuma domestica Vall) SEBAGAI PELEMBAB KULIT Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i2.652

Antioxidants is contained in various types of fruit and vegetables included of juice tomatoes (Lycopersicum esculentum Mill)that have nutritional value and benefits for the body like lycopene, and vitamin C as antioxidants. Lycopene is function as a strong antioxidant to control free radical. Tumeric (Curcuma domestica Vall) is known have enough curcumin and strong antioxydants content too, and so it has some pharmacological effects. Tomatoes and Tumeric extract (EKSBT) can be made as pharmaceutical preparations in hand and body lotion (H&B lotion),because antioxidants are important components that are used for body protection from ultra violet light and can be applied in the form of a lotion. The purpose of this study was to saw the stability of the H&B lotion combination of that Variations.Combination tomatoes and turmeric extract formulated with concentrations lotion are of 5%, 10%, and 15%. The lotion of EKSBT these combination were evaluated some test there are organoleptic, homogeneity, pH test, spreadability, irritation and preference test.EKSBT combination can be formulated into lotion preparations. The various of all concentrations lotion EKSBT showed that stable during instorage, give a homogeneous yellow color with pH of 5-6 and a spread of 5-6 cm, does not irritate the skin and is preferably the volunteer.Physical stability EKSBT lotion test all concentration are stable, the preferred test of odor, easy to be smeared and moisturizing shows that the most preferred EKSBT lotion is the highest concentration 15%.

UJI FORMULASI SEDIAAN SALEP EKSTRAK ETANOL DAUN PACAR (Lawsonia inermis L.) TERHADAP BAKTERI Staphylococcus aureus DAN Pseudomonas aeruginosa Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.767

Background: Indonesia is a country rich in natural resources that can be used as traditional medicine. Pacar leaf extract (Lawsonia inermis L.) can be formulated into ointment preparations, can inhibit the growth of staphylococcus aureus (SA) and pseudomonas aeruginosa (PA) bacteria and determine the best inhibitory concentration. Methods: This research method was experimental, the extract was obtained by maceration method with 80% ethanol solvent, then ointment was made using adeps lanae base, vaseline album and Pacar leaf extract ointment hadcombination concentrations 8%, 12% and 16%. The results of the study: The results showed that Pacar Leaf Extract (SEEDP)could be formulated as an ointment preparation and met the requirements for quality testing of ointment preparations, including characterization tests and phytochemical screening tests. The results of the antibacterial activity test showed that the formulation of the ointment preparations of Pacar Extract with concentrations of 8%, 12% and 16% could inhibit the growth of bacteria and good inhibition of 16% with an average diameter of bacteria (SA). 11.93 mm and bacteria (PA) 17.2 mm.It was concluded that the higher the concentration of the extract, the greater the inhibition given. The preparation of pacar leaf extract ointment with concentrations of 8%, 12% and 16% was the best ointment in inhibiting the growth of bacteria (SA) and (PA)

PENYULUHAN TENTANG SAMPAH BONGKOL NANAS YANG DIGUNAKAN SEBAGAI ANTISEPTIK DI DESA SIDODADI PATUMBAK Nina Irmayanti Harahap; Angga Nugraha Sanjaya
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

People use pineapples, one of which is as a cooking ingredient where pineapples are processed and eaten or can be served directly. However, what is not widely known by the public is that pineapple can be used as an antiseptic because pineapple has antibacterial activity. In the manufacture of this antiseptic where only the pineapple hump is used. So far, the pineapple weevil is known to the public only as garbage and cannot be used for anything, but the pineapple weevil can be used as an antiseptic, so that people can know and not throw away the pineapple weevil, but the community can use it as an antiseptic. With this counseling, the community in SidodadiPatumbak Village can know and practice what has been conveyed.

PENYULUHAN TENTANG MANFAAT BATANG SERAI (Cymbopogon Citratus) BAGI PASIEN INSOMNIA DI RUMAH SAKIT SEMBIRING Nina Irmayanti Harahap; Sofia Rahmi; Palas Tarigan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

A condition characterized by a disturbance in the amount, quality or time of sleep in an individual is often referred to as insomnia. Sleep disturbances can interfere physically, emotionally, cognitively, and socially in adults. The magnitude of the possibility of academic, emotional, health, and behavioral problems in adults can be prevented or corrected, this fact shows significantly through intervention, through improving the quality and quantity of sleep by having the advantages of lemongrass aromatherapy which without causing side effects at all is able to overcome the reduction of insomnia. Citronella essential oil has been used for centuries to reduce rashes, inflammation, infection, pain and other health conditions. The method used through health education is aimed at achieving changes in the behavior of individuals, families and communities in fostering and maintaining health, playing an active role in optimizing health in accordance with healthy living physically, mentally and socially. Providing counseling with the method used is the lecture method by explaining and explaining an understanding, idea or message orally to the target group.

Activity Testing Of Dahlia (Dahlia Variabilis) Tubers Against Escherichia Coli And Salmonella Typhi Bacteria In Vitro Zola Efa Harnis; Nina Irmayanti Harahap; Rika Puspita Sari; Putri Andini
Journal of Midwifery and Nursing Vol. 4 No. 3 (2022): Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v4i3.2403

Dahlia tubers are a source of carbohydrates in the form of inulin. Dried dahlia tubers are thought to contain inulin as much as 65-76% of the total carbohydrates contained. Inulin or fructoolgosaccharide is a food component that can act as a prebiotic and also as a soluble dietary fiber in humans. Inulin is thought to be able to maintain the balance of the other normal flora of the large intestine. The balance of microflora in the intestine is very necessary because these microbes can inhibit the growth of pathogenic bacteria. Escherichia coli and Salmonella typhi are among the choliform bacteria belonging to the Enterobacteriaceae family. Enterobacteriaceae are enteric bacteria or bacteria that live and can survive in the digestive tract. This study aims to compare the activity of dahlia tuber starch against Escherichia coli and Salmonella typhi bacteria by determining the activity of dahlia tuber starch. The results showed that dahlia tuber starch had antibacterial activity against Escherichia coli and Salmonella typh. Effective concentration in inhibiting Escherichia coli and Salmonella typhi bacteria at a concentration of 80% with an average LDH of 22.71 mm for Escherichia coli bacteria, while for Salmonella typhi the average LDH of 15.08 mm.

Anti-Bacterial Activity Testing Of Batak (Allium Chinense G. Don.) Leaf Ethanol Extract Against The Bacteria Propionibacterium Acnes, Staphylococcus Aureus, Escherichia Coli And Salmonella Thyph Nina Irmayanti Harahap; Rika Puspita sari; Zola Efa Harnis; Sri Rezeky
Journal of Midwifery and Nursing Vol. 4 No. 3 (2022): Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v4i3.2404

Batak onion (Allium chinense G.Don) of the Amarylidaceae family is one of the traditional medicinal plants that has antibacterial properties, containing flavonoids, terpenoids, tannins and saponins. EEDBB extract against Propionibacterium acne (Pa), Staphylococcus aureus (Sa), Eschericia coli (Ec), Salmonella typhi (St). Batak shallot powder was extracted by maceration method using 80% ethanol as solvent. disc diffusion method of advertising concentration (EEDBB) 40%, 60%, 80% with a comparison of positive control and negative control. Measurement of antibacterial activity showed that all concentrations had antibacterial activity. The highest antibacterial activity of EEDBB at a concentration of 80% had a maximum antibacterial with an average inhibition zone of 11.5 mm for bacteria (Pa), 10 mm for bacteria (Sa), 15,5 mm for bacteria (Ec) and 16.1 mm for bacteria. bacteria (St). The lowest antibacterial activity ethanol extract at a concentration of 40% had the lowest inhibitory power with an average inhibition zone diameter of 7.8 mm for bacteria (Pa), 6.6 mm for bacteria (Sa), 12.9 mm for bacteria (Pa). . bacteria (Ec) and 13.2 mm in bacteria (St). EEDBB has the highest antibacterial activity on bacteria (St) with an average inhibition zone of 16mm. Data analysis was carried out using the One way ANOVA test, namely H0 was accepted and H1 was rejected where the value of sig < 0.05.

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Rambutan (Nephelium lappaceum L) Pada Pertumbuhan Bakteri Staphylococcus aureus dan Escherichia coli Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.936

The purpose of this study was to determine that the ethanolic extract of rambutan leaves (Nephelium lappaceum L) has antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria. As an antibacterial comparator used Amoxicillin. Each leaf of sample was extracted with maceration methode using 70% of ethanol solvent. Where it 2 to 3 days with several stirring times then it filtered, then the filtrate result was thickened with vacuum rotary evaporator. The antibacterial activity test used the paper disc diffusion method and was observed based on the diameter of the inhibition zone or the clear zone formed around the paper discs and slots which used with three times treatments. Result test of antibacterial activity of rambutan leaf ethanol extract (Nephelium lappaceum L) with these method showed that the extract actively inhibited the growth of Staphylococcus aureus bacteria with Minimum Inhibitory Concentration (MIC)3.125% with a 7.96 mm, but not showed for the growth of Escherichia coli bacteria.

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