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All Journal INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES TEKNIK Jurnal Kedokteran Brawijaya Jurnal Kesehatan Olahraga SPEKTRUM INDUSTRI PRIVATE LAW Jurnal Teknologi Pertanian Fakultas Ekonomi Jurnal Ilmiah Teknik Industri Majalah Obat Tradisional GEMA INDONESIAN JOURNAL OF PHARMACY MNJ (Malang Neurology Journal) JURNAL HAMA DAN PENYAKIT TUMBUHAN TROPIKA Universa Medicina Jurnal Sistem dan Manajemen Industri JURNAL PENDIDIKAN TAMBUSAI Jurnal Migasian Akamigas Balongan Indramayu Border: Jurnal Arsitektur Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Assets : Jurnal Ilmiah Ilmu Akuntansi, Keuangan dan Pajak
HARI PURNOMO
Fakultas Peternakan, Universitas Brawijaya Malang, Malang
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Transportation

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Efek Ekstrak Propolis terhadap Ekspresi TNF-α, Apoptosis dan Nekrosis Jaringan Otak Tikus Model Traumatic Brain Injury (TBI) Dewi, Ashalia Chandra; Ali, Mulyohadi; Purnomo, Hari
Jurnal Kedokteran Brawijaya Vol 29, No. 2 (2016)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2016.029.02.4

Abstract

Ekstrak propolis merupakan produk lebah dengan berbagai kandungan aktif yang memiliki efek antioksidan, antiinflamasi, proteksi DNA, neuroprotektan dan immunomodulator. Propolis mampu menurunkan reaksi inflamasi melalui hambatan terhadap aktivitas TNF-α dan NF-κB, mampu menurunkan Bax dan caspase-3, dan meningkatkan Bcl-2, yang berperan pada jalur apoptosis. Propolis berpotensi sebagai terapi alternatif dalam menurunkan inflamasi, apoptosis dan nekrosis pada traumatic brain injury (TBI) via modulasi ekspresi TNF-α. Penelitian ini bertujuan untuk menguji pengaruh pemberian ekstrak propolis dalam berbagai dosis pada ekspresi TNF-α, apoptosis dan nekrosis pada jaringan otak tikus model TBI. Sampel dibagi menjadi 5 kelompok, yaitu: kontrol negatif, kontrol positif, kelompok model trauma dan diberi perlakuan propolis masing-masing dosis 50, 100, dan 200mg/kgBB/h. Pada akhir penelitian, tikus dikorbankan dan dibuat preparat otak untuk menilai ekspresi TNF-α, jumlah sel apoptosis dan area nekrosis. Ekspresi TNF-α, apoptosis dan nekrosis lebih rendah pada kelompok TBI yang mendapatkan ekstrak propolis 50, 100, dan 200mg/kgBB/h (p=0,000). Penelitian ini membuktikan bahwa ekstrak propolis berpengaruh dalam penurunan ekspresi TNF-α, apoptosis dan nekrosis jaringan otak tikus model TBI.Kata Kunci: Apoptosis, ekstrak propolis, ekspresi TNF-α, nekrosis, traumatic brain injury
PENGARUH LATIHAN LADDER DRILL TWO FEET EACH SQUARE TERHADAP PENINGKATANKECEPATAN GERAK PURNOMO, HARI
Jurnal Kesehatan Olahraga Vol 4, No 4 (2016): Edisi November 2016
Publisher : Jurnal Kesehatan Olahraga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kecepatan adalah waktu yang dibutuhkan oleh tubuh untuk melakukan suatu kerja fisik tertentu. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan sebelum dan sesudah melakukan latihan ladder drill two feat each square terhadap peningkatan kecepatan gerak. Dalam penelitian ini menggunakan jenis penelitian eksperimendengan adanyapre-test dan post-test. Sampel penelitian sebanyak15. Dari hasil penelitian diperoleh rata-rata kecepatan gerak padapre-test sebesar 5,747 dan pada post-test sebesar 5,536. Uji normalitas data pre-test diperoleh x2tabel lebih besar dari x2hitung (5,991 > 3,455) dan post-test (5,991 > 2,291), sehingga kedua data tersebutberdistribusi normal. Hasil dari perhitungan uji perbedaan rata-rata kecepatan gerak sebelum dan sesudah diberi latihan menggunakan ladder drill two feet each square diperoleh thitung -2,478 dan nilai ttabel dengan taraf signifikansi 0,05 dengan df = 14 adalah 2,977. Karenathitung lebih kecil dari ttabel (-2,478 < 2,977), maka H1 diterima yang berarti ada perbedaan kecepatan gerak sebelum dan sesudah diberikan latihan ladder drill two feet each square.
KOMPATIBILITAS CENDAWAN METARHIZIUM ANISOPLIAE (METSCHN.) SOROKIN DENGAN NEMATODA ENTOMOPATOGEN STEINERNEMA SP. Rosyidi, Imron; Purnomo, Hari; Haryadi, Nanang Tri; Hoesain, Mohammad
JURNAL HAMA DAN PENYAKIT TUMBUHAN TROPIKA Vol 17, No 2 (2017): SEPTEMBER, JURNAL HAMA DAN PENYAKIT TUMBUHAN TROPIKA
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.283 KB) | DOI: 10.23960/j.hptt.217111-118

Abstract

Compatibility Metarhizium anisopliae (Metschn.) Sorokin with entomopathogenic nematode Steinernema sp. Metarhizium anisopliae (Metschn.) Sorokin and entomopathogenic nematode Steinernema sp. can be used as biological control of insect pests. The objective of this research was to identify compatibility between fungus M. anisopliae with entomopathogenic nematode Steinernema sp. This research was conducted using a completely randomized design (CRD) consisting of 5 treatments and repeated 5 times. The treatment used was M. anisopliae isolates Jombang 1 with Steinernema sp. (M1), M. anisopliae Jombang 2 with Steinernema sp. (M2), M. anisopliae isolates Kediri with Steinernema sp. (M3), M. anisopliae isolates Bondowoso with Steinernema sp. (M4), and M. anisopliae isolates Banyuwangi with Steinernema sp. (M5). Based on this research result, compatibility between the fungus M. anisopliae with entomopathogenic nematode Steinernema sp. was antagonistic. This occurs due to the symbiotic bacteria Xenorhabdus sp. that produced compounds antimycotic and capable to inhibit the growth of fungus M. anisopliae.
Korelasi TNF Alpha dan Interleukin 6 dengan Prognosis Stroke Infark Trombotik Akut Gunawan, Gerry; Sujuti, Hidayat; Purnomo, Hari
Jurnal Kedokteran Brawijaya Vol 28, No 4 (2015)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.847 KB) | DOI: 10.21776/ub.jkb.2015.028.04.11

Abstract

Stroke adalah gangguan aliran darah ke otak yang terjadi mendadak dan bertahan dalam waktu lebih dari 24 jam yang dapat menimbulkan kecacatan. NIHHS merupakan alat ukur yang digunakan untuk menilai keluaran dari stroke. Penelitian ini bertujuan untuk mengetahui korelasi kadar TNF-α  dan IL-6 serum dengan status neurologis pasien stroke infark trombotik akut yang dinilai dengan skor NIHSS awal, mengetahui korelasi antara tingginya kadar TNF-α dan IL-6 serum dengan perburukan status neurologis pasien stroke infark trombotik akut yang dinilai dengan delta skor NIHSS, mengetahui korelasi antara TNF-α serum dan IL-6 serum pasien stroke infark trombotik akut, dan mengetahui korelasi antara kadar TNF-α  dan IL-6 serum dengan keluaran status neurologis pasien stroke infark trombotik akut yang dinilai dengan skor NIHSS akhir. Penelitian ini merupakan penelitian analitik observasional dengan melakukan pengambilan sampel darah dan pengukuran skor NIHSS pada jam ke 30 setelah onset stroke infark trombotik akut serta pengukuran skor NIHSS pada hari ke 10 setelah onset stroke infark trombotik akut. Sampel darah dilakukan pemeriksaan kadar TNF-α dan IL-6 serum dengan metode ELISA. Terdapat korelasi signifikan yang berbanding lurus antara skor NIHSS awal dengan kadar  TNF-α dan IL-6 serum, skor NIHSS akhir dengan kadar TNF-α dan IL-6 serum, kadar IL-6 serum dengan kadar  TNF-α serum. Terdapat korelasi signifikan yang berbanding terbalik antara delta skor NIHSS dengan kadar  TNF-α dan IL-6 serum. Semakin tinggi kadar TNF-α dan IL-6 serum, maka prognosis akan semakin buruk.Kata Kunci: IL-6, NIHSS, prognosis, TNF-α, stroke trombotik
AGGRAVATE OR MITIGATE? HOW COST ANALYSIS ASSOCIATED INTO RISK MANAGEMENT PROCESS Cahyo, Winda Nur; Trialopa, Eky Fasich; Purnomo, Hari
Jurnal Ilmiah Teknik Industri Vol. 19, No. 1, June 2020
Publisher : Muhammadiyah University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jiti.v19i1.10390

Abstract

In most researches in the area of risk management, the result stops at proposing the mitigation strategies. The number of researches on associating cost analysis into the risk management process is very limited. This paper proposes a practical process on how cost analysis can be associated into the risk management process especially in the area of manufacturing. The process of the risk management is conducted as usual, started by selecting the potential risk and finding the major causes. Then, a risk map and its rubric of risk likelihood and severity are developed, and the major causes are plotted into it to select the priority of the major causes and the proposed mitigation strategy is developed. Then, the poposed strategy is compared with the current strategy based on the cost generated using the developed equation. The result shows the proposed mitigation strategy is selected because it saves approximately IDR 2 million per order. It indicates that cost analysis can be successfully associated into the risk mitigation process and generates a comprehensive recommendation to the decision maker.
THE INFLUENCE OF SAMPLING TIME TO SERUM GLIAL FIBRILLARY ACIDIC PROTEIN (GFAP) LEVELS IN ACUTE STROKE Raisa, Neila; Sujuti, Hidayat; Purnomo, Hari; Rahayu, Masruroh; Dalhar, Mochamad
Malang Neurology Journal Vol 5, No 1 (2019): January
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2019.005.01.5

Abstract

Background: Serum Glial Fibrillary Acidic Protein (GFAP) is a great potential for biomarker that is widely studied as a diagnostic biomarker of acute stroke. Sampling within 6 hours after onset is the best time window, but in Indonesia, stroke patients often arrive late more than 6 hours.Objective: To identify the difference in time of blood sampling with serum GFAP levels within 24 hours onset of ischemic stroke (IS) patients and intracerebral hemorrhage (ICH) strokes.Methods: Cross-sectional analysis with purposive sampling, sampling in IS and ICH strokes that arrive at the ER within 24-hour on-site. The serum GFAP examination was performed with ELISA.Results: In this study, 41 acute stroke patients with 24-hour onset of each stroke were grouped into group 1 (<6 hours), group 2 (6-12 hours) and group 3 (12-24 hours). One Way ANOVA and Tukey's analysis showed no significant difference in GFAP levels among the three groups in both IS and ICH. Conclusion: There was no significant difference in GFAP levels in samples <6 hours, 6-12 hours, and 12-24 hours in ischemic strokes and ICH strokes.
Peranan Kepala Desa dalam Pelaksanaan Pembangunan di Kota Tual, Kecamatan Pulau Dullah Utara, Desa Ohoitahit Purnomo, Hari; Suljatmiko, Suljatmiko
Jurnal Pendidikan Tambusai Vol. 6 No. 1 (2022): April 2022
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (139.534 KB)

Abstract

Budaya Indonesia banyak ditemukan di daerah pedesaan. Oleh karena itu, menjadi bagian dari upaya pembangunan dan pembangunan desa menjadi pusat perhatian pemerintah. Pemerintah desa merupakan pemerintahan formal kesatuan masyarakat desa, sebagai badan kekuasaan terendah, pemerintah desa mempunyai kekuasaan atau kewenangan untuk mengatur rumah tangganya sendiri (otonomi desa) serta kewenangan dan kekuasaan sebagai pelimpahan dari pemerintah di atasnya, dimana desa merupakan tempat segala urusan semua elemen kesatuan masyarakat. desa. Untuk mencapai tujuan pembangunan desa yang merupakan bagian penting dari pembangunan. Artinya, pelaksanaan dan tanggung jawab pembangunan diserahkan kepada kepala desa sebagai koordinator dan pelaksana pembangunan desa yang dipimpinnya. Desa Ohoitahit sampel karena alasan desa ini dilihat dari perkembangan fisik yang tertinggal dibandingkan desa lain di Kota Tual, Kec. Pulau Dullah Utara, Desa Ohoitahit. penyusunan perencanaan pembangunan yaitu di Kota Tual, Kec. Pulau Dullah Utara Desa Ohoitahit direncanakan perbaikan jalan ditargetkan sepanjang 30 km dengan biaya Rp. 1.000.000.000,- realisasi Rp. 30.000.000,- dan pembangunan gedung SMP membutuhkan dana sebesar Rp. 750.000.000. Selanjutnya, target pembangunan MDA adalah Rp. 200.000.000,- yang belum terealisasi. Selanjutnya, informasi PLTD ditargetkan sebesar Rp. 250.000.000 belum terealisasi sesuai rencana, perencanaan informasi desa ditargetkan untuk menerangi 204 KK, namun belum terlaksana.
MANAGEMENT OF VILLAGE FUNDS IN ACCORDANCE WITH PERMENDAGRI NUMBER 20 OF 2018 Saputro, Adi; Sholihin, Muhammad Rijalus; Purnomo, Hari
Assets : Jurnal Ilmiah Ilmu Akuntansi, Keuangan dan Pajak Vol. 5 No. 2 (2021): July-December
Publisher : Institut Teknologi dan Bisnis Widya Gama Lumajang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (768.835 KB) | DOI: 10.30741/assets.v5i2.691

Abstract

The purpose of this study was to determine the suitability of the Village Fund (DD) financial management cycle in Kunir Lor Village, Kunir District, whether it was in accordance with the cycle. village financial management as regulated in the Minister of Home Affairs Regulation (Permendagri) number 20 of 2018 and to describe the Village Fund Management (DD) accountability system in Kunir Lor Village, Kunir District, Lumajang Regency. This type of research is descriptive research with a qualitative approach where the data obtained from the Office of the Village Hall of Kunir Lor, Kunir District, Lumajang Regency in the form of interviews, documentation, and questionnaires. The data used is primary data, where the data is processed from published data. The results of this study state that the management of village funds is divided into several stages including the planning stage, implementation stage, administration stage, reporting stage and accountability stage to Kunir Lor Village. process whose implementation is still considered ineffective.
The Role of the Village Head in the Implementation of Development in Tual City, Pulau Dullah Utara District, Ohoitahit Village Purnomo, Hari; Suljatmiko, Suljatmiko
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 5, No 1 (2022): Budapest International Research and Critics Institute February
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v5i1.4019

Abstract

Indonesian culture mainly exists in rural areas. Therefore, what must be considered in development work and village development is the government's priority. The village government itself is the official government of the village community unit. As one of the lowest governmental powers, the village level government does not only have the power or power to manage its own affairs (village level autonomy). But also has decentralized and superior power level government. Where the village is the location of all offices for all elements of the community unit in the village. Achieving village development goals is an important part of development. This means that the village head as the coordinator and implementer of village level development led by the village head delegates responsibility for implementation and development to the village head. Ohoitahit Village was chosen as the sample because its physical development lags behind other villages in Jalan Tual Village. North Dura Island. Ohhoitahit Village. A development plan was drawn up for the town of Tual in the area. A 30 kilometer long road is planned to be built on North Dura Island in Ohhoitahit Village at a cost of Rp. 1,000,000,000 - up to Rp. The construction of this junior high school requires a capital of Rp. 30 million. 750,000,000. In addition, the target for MDA development is Rp. 200,000,000, - has not been implemented. In addition, information on PLTD is Rp. 250 million were not completed according to plan, and the village information planning objective explained that 204 households were not completed as planned.
Co-Authors ADI SAPUTRO Adnyana Manuaba Agung Endro Nugroho Ahmad Mukoffi, Ahmad Anastasia Novitasari, Anastasia Angga Wenang Sakti Anindita, Jessica Annisa Nurul Arofah, Annisa Nurul Apsari, Ayudyah Eka Arief Rahman Hakim Balafif, Farhad Cahyo, Winda Nur Catur Ari Setianto, Catur Ari Dalhar, Mochamad Dani Dwi Agistia, Dani Dwi Dewi, Ashalia Chandra Dian Janari Eko Arisetijono Ernawati Ernawati Fitriani, Ayi Gerry Gunawan, Gerry Hadyanawati, Anindya Agripina Haripurna, Angga Hidayat Sujuti Hoesain, Mohammad I Nyoman Adi Putra Imron Rosyidi, Imron Indarti, Adrian Iwan Adi Indrawan Kobajashi T. Isamu Lestari, Vitri Made Ayu Hariningsih, Made Ayu Mafita Azizah Hidayati, Mafita Azizah Masruroh Rahayu, Masruroh Maulana Tegar, Maulana Mindhayani, Iva Mochammad Dalhar Moh. Saprawi, Moh. Muhammad Faqih Mulyohadi Ali Nanang Tri Haryadi Nastiti Septi Kinasih Nurjannah, Anisa Pramesti, Fathia Annis Pudjono, Pudjono R. Sapto Hendri Boedi Soesatyo Rachmat Adiyanto Raisa, Neila Retty Ratnawati Sadiq Ardo Wibowo, Sadiq Ardo Sari, Galuh Masita Sartika Dewi Utami, Sartika Dewi Sholihin, Muhammad Rijalus Sri Budhi Rianawati, Sri Budhi Sudarminto Setyo Yuwono Suljatmiko, Suljatmiko Suwarto, Sigit Teti Estiasih Tri Apri Yudianto Trialopa, Eky Fasich Wahyu Ismail Kurnia Widodo Mardi Santoso, Widodo Mardi Widodo, Imam Djati