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Perspektif Historis Kesadaran Kebangsaan dan Kemerdekaan Indonesia Berdimensi Kebudayaan Purwanto, Bambang
Historia: Jurnal Pendidik dan Peneliti Sejarah Vol 2, No 2 (2019): Pendidikan Sejarah abad 21
Publisher : Prodi. Pendidikan Sejarah FPIPS UPI dan APPS (Asosiasi peneliti dan Pendidik Sejarah)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.67 KB) | DOI: 10.17509/historia.v2i2.16636

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Cita-cita Indonesia sebagai kesatuan bangsa yang merdeka mulai terancam, ketika sekelompok elite politik dan masyarakat tertentu mulai membayangkan untuk tidak lagi menjadi bagian dari rumah besar Indonesia. Keadaan ini menyadarkan semua pihak bertapa pentingnya historiografi dan memori kolektif bangsa dalam membentuk, memahami, dan memelihara kesadaran kebangsaan dan kemerdekaan Indonesia sebagai cara berpikir yang integratif dan menyeluruh. Berbeda dengan kajian yang ada selama ini yang hanya menekankan pada dimensi politik, tulisan ini menempatkan kesadaran kebangsaan dan kemerdekaan indonesia dalam ruang dimensi kebudayaannya. Ketika kesadaran kebangsaan dan kemerdekaan dipahami dalam dimensi kebudayaan, maka Proklamasi 17 Agustus 1945 bersama-sama Pancasila tidak lagi dapat disebut sebagai produk politik semata, melainkan sebagai kebudayaan bangsa
FEMINIST APPROACH IN ANN BRASHARES’S THE SISTERHOOD OF THE TRAVELING PANTS Purwanto, Bambang
Language Circle: Journal of Language and Literature Vol 4, No 1 (2009): October 2009
Publisher : Faculty of Languages ​​and Arts, State University of Semarang

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The purpose of this writing is to express that friendship is more important than hostility. The reason of hostility is annoyance, emotion and lack of patience in facing problems. The effect of it is the destruction of friendship and the increase in annoyance among them. Feminist is a method that is used in this writing. The application of this method is to express that man and woman have the right to make their own decisions. Both of them will respect and understand. They will have responsibility for everything they have done. This method is also expressing that human have freedom in their life. In this novel, there are four women. They are Carmen, Bridget, Lena and Tibby. The four of them spend their summer holiday into different places. In their summer holiday, they have experienced incidents which can destroy friendship. Carmen hates her father, Lena hates Kostos, Bridget hates Eric and Tibby hates Bailey. Finally, they realize that annoyance between them can destroy their friendship. The writer used Feminist approach because the main characters wanted to destroy the patriarchy of man. They insist that man can respect woman’s opinion.   Key words: Friendship, Conflict, Respect
Pengaruh Suplementasi Vitamin C, Vitamin E, dan Kombinasinya Terhadap Penurunan Kadar Low Density Lipoprotein Serum pada Pasien Penyakit Ginjal Kronis Stadium V yang Dilakukan Hemodialisis Dewi, Ayu Kusuma; Purwanto, Bambang; Wiboworini, Budiyanti
Jurnal Kedokteran Indonesia Vol 3, No 1 (2012)
Publisher : Jurnal Kedokteran Indonesia

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Background:Low density lipoprotein (LDL) cholesterol is a prognostic factor for hemodialysis mortality through atherosclerosis mechanism. Vitamin C and E have been well known as anti-oxidants that reduced LDL cholesterol. However, there were no studies have been done to address the effectiveness of vitamin C, E, and its combination on lowering LDL in patients with hemodialysis. This study aimed to determine the effect of vitamin C, E, and C and E combination on LDL cholesterol. Methods:A randomized controlled trial was conducted in 64 patients receiving hemodialysis at RSUD Dr.Moewardi(RSDM) Surakarta. The sample was taken at random and then divided into 4 groups: placebo, vitamin C (500 mg), vitamin E (400 mg), and vitamin C + E combination. The treatment lasted for 30 days. LDL cholesterol before and after treatment were analyzed at the Clinical Pathology division, RSDM. The reduction in LDL cholesterol before and after treatment was analyzed using One Way Anovaand (pair-wise) Post-Hoc Test. Results:One Way Anovashowed statistically significant reduction in LDL cholesterol between groups (p<0.001). Post hoc testshowed that vitamin C, vitamin E, or its combination reduced LDL cholesterol more than the placebo (p<0.001). Vitamin C and E administered in combination led to statistically significant lower LDL cholesterol than administered alone (p=0.002). There was no statistically difference in LDL cholesterol level between those provided with vitamin C and vitamin E. Conclusion: Vitamin C and E, individually or in combination, reduces LDL cholesterol. The highest reduction was achieved by vitamin C and E combination.Keywords: vitamin C, vitamin E, LDL cholesterol
Memahami Kembali Nasionalisme Indonesia Purwanto, Bambang
Jurnal Ilmu Sosial dan Ilmu Politik Vol 4, No 3 (2001): Refleksi Nasionalisme Indonesia
Publisher : Fakultas Ilmu Sosial dan Ilmu Politik Universitas Gadjah Mada

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Nationalism is a given cultural reality which keeps changing its meaning through out our history. Such changing is partly due to a manipulative exercise by the rulers, partly through socialization of the so called national history. Societal conflict and tention emerged in many part of Indonesia recently has been due to unfinished transformations, yet pursuing the manipulative path of nationalization of nationalism lead us to absurdity of our collective identity. Reconstructing Indonesian historiography is an imperative, whithin which local history should have a fair treatment.
Efek Probiotik pada Kadar IgA Mencit Model Sepsis Prasetyo, Diding Heri; Purwanto, Bambang
Majalah Kedokteran Bandung Vol 42, No 4
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Probiotik berfungsi sebagai imunomodulator dan imunonutrisi pada penderita penyakit kritis seperti sepsis, tetapi mekanismenya belum diketahui secara pasti. Penelitian ini bertujuan untuk menentukan efek pemberian probiotik pada kadar IgA mencit model sepsis di Rumah Sakit dr. Moewardi/Fakultas Kedokteran Universitas Sebelas Maret Surakarta periode Juli 2009–2010. Hewan uji berupa 18 ekor mencit Balb/C jantan yang dibagi menjadi tiga kelompok. Kelompok I tanpa diberi perlakuan (kontrol negatif), kelompok II adalah mencit model sepsis yang diinokulasi dengan lipopolisakarida (LPS)-E.coli (0,4 mg/mencit/i.p.), dan kelompok III adalah mencit model sepsis yang diinokulasi dengan LPS-E.coli serta diberi probiotik. Kadar IgA serum diperiksa dengan menggunakan ELISA. Data dianalisis secara statistik dengan one way ANOVA. Kadar IgA serum pada kelompok mencit normal 35,82±4,55 ng/mL. Pemaparan LPS-E.coli menurunkan kadar IgA serum menjadi 6,20±5,80 ng/mL. Pemberian probiotik pada mencit model sepsis, mampu meningkatkan kadar IgA serum menjadi 65,07±34,97 ng/mL. Probiotik secara bermakna meningkatkan kadar IgA serum dibandingkan dengan kelompok mencit sepsis (65,07±34,97 ng/mL vs 6,20±5,80 ng/mL, p=0,000). Simpulan, pemberian probiotik meningkatkan kadar IgA serum pada mencit model sepsis. [MKB. 2010;42(4):175–80].Kata kunci: IgA, probiotik, sepsisThe Effect of Probiotic on IgA Level in Mice Model of SepsisProbiotic is useful as immunomodulator and imunonutrition in patients with critical illness such as sepsis, but the mechanism is not entirely clear. This study was aimed to evaluate the effect of probiotic on serum IgA level in mice model of sepsis in dr. Moewardi Hospital/Faculty of Medicine, Universitas Sebelas Maret Surakarta period July 2009–2010. Eighteen males Balb/C mice were used and divided into three groups. Group I without treatment (negative control), group II which was mice model of sepsis inoculated with lipopolysaccharide (LPS)-E.coli (0.4 mg/mouse/ip), and group III was mice model of sepsis inoculated with E. coli LPS-and given probiotic. Serum IgA level was examined by ELISA. Data were analyzed statistically with one-way ANOVA. Serum IgA levels in normal mice group was 35.82±4.55 ng/mL. Exposing LPS-E. coli reduced the levels of serum IgA to 6.20±5.80 ng/mL. Administration of probiotics increased the serum IgA level to 65.07±34.97 ng/mL in mouse models of sepsis. Probiotics significantly increased serum IgA levels compared to mice model of sepsis group (65.07 ± 34.97 ng / mL vs. 6.20 ± 5.80 ng / mL, p = 0.000). In conclusion, administration of probiotics can increase the levels of serum IgA in mice model of sepsis. [MKB. 2010;42(4):175–80]. DOI: http://dx.doi.org/10.15395/mkb.v42n4.33
Green Tea (EGCG) Decreases Malondialdehide In Oxidative Stress Exposure To Psychological Stress Adriani, Merryana; Purwanto, Bambang; Wirjatmadi, Bambang; Priaminda, M Dodi F
Health Notions Vol 2 No 7 (2018): July 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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PENGARUH RADIOTERAPI EKSTERNAL TERHADAP FUNGSI SEL RAMBUT LUAR KOKLEA PENDERITA KARSINOMA NASOFARING Purwanto, Bambang; Samiadi, Dindy; Nurmasari, Shinta
Majalah Kedokteran Bandung Vol 42, No 2
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Pilihan utama pengobatan karsinoma nasofaring adalah radioterapi. Pemberian radioterapi dosis tinggi menimbulkan kerusakan struktur jaringan, salah satunya adalah gangguan pendengaran. Gangguan di koklea timbul akibat kerusakan struktur sel rambut akibat degenerasi stria vaskularis, atrofi spiral ligamen, dan membran basilaris. Tujuan penelitian adalah untuk mengetahui fungsi sel rambut luar koklea akibat radioterapi penderita karsinoma nasofaring. Tipe penelitian adalah studi analitik observasional dan dilakukan di Bagian IK.THT-KL/RS. Hasan Sadikin Bandung mulai Maret sampai September 2007. Dilakukan pemeriksaan audiometri, timpanometri, dan emisi otoakustik (otoacoustic emission)/OAE sebelum radioterapi, serta pemeriksaan timpanometri serta OAE saat radioterapi dan satu bulan pascaradioterapi. Untuk menguji pengaruh radioterapi eksternal digunakan uji McNemar dan uji Z. Diperoleh 42 telinga dari 27 subjek penelitian yang memenuhi kriteria inklusi. Didapat 18 lakilaki dan 9 perempuan. Hasil penelitian menunjukkan insidens gangguan fungsi sel rambut luar koklea sebesar 9,6% pada dosis 2.000 cGy, 61,5% pada 4.000 cGy, 81,1% pada 6.600 cGy, dan 82,8% satu bulan pascaradiasi. Hubungan gangguan fungsi sel rambut luar koklea memberikan nilai sangat bermakna pada dosis 4.000 cGy sampai 6.600 cGy (p<0,001). Kesimpulan penelitian radioterapi eksternal penderita karsinoma nasofaring menyebabkan gangguan fungsi sel rambut luar koklea.Effect of External Radiotherapy to Cochlear Outer Hair Cells Function on Nasopharyngeal Carcinoma PatientsRadiotherapy is the main treatment of nasopharyngeal carcinoma. Exposure to high dose radiotherapy can cause damage to the surrounding tissue structure and hearing loss is one of it. Depraved cochlea is occur due to damaged outer hair cells (OHC) because of degeneration of striae vascularis, spiral ligament, and bacillar membrane atrophy. The purpose of this study was to understand the OHC's function due to radiotherapy in nasopharyngeal carcinoma patients. The type of study was observational analytic study with prospective design to determine the influence of radiotherapy to the function of OHC in the department of ENT-HNS Hasan Sadikin General Hospital Bandung and performed from March to September 2007. Pure tone audiometry examination, tympanometry, and otoacoustic emission (OAE) was performed before radiotherapy. Tympanometry and OAE was measured when radiotherapy performed and one month after radiotherapy. McNemar and Z test was performed to calculate the effects of radiotherapy to OHC. In this study 42 ears from 27 subjects that meet the inclusion criteria 18 men and 9 women. The result of this study showed that the prevalence of damaged OHC were 9.6% at 2,000 cGy, 61.5% at 4,000 cGy,81.1% at 6,600 cGy, and 82.8% after one month of radiotherapy. Damaged OHC's function was significance at dose radiation exposure from 4,000 to 6,600 cGy (p<0.001). The conclusion of this study is radiotherapy can alter OHC's function in patients with nasopharyngeal carcinoma.DOI: http://dx.doi.org/10.15395/mkb.v42n2.12 
PENAMBAHAN BESAR SUDUT INKLINASI INSOLE SEPATU KERJA MENURUNKAN KADAR GLUKOSA DARAH PUASA DAN HbA1c kusuma, herdianty; Abdullah, Ahmad; Purwanto, Bambang; Suhartatik, Suhartatik
Jurnal NERS Vol 11, No 1 (2016): Jurnal Ners
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.971 KB) | DOI: 10.20473/%oj.Ners111%y29-33

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Introduction: Running downhill improved the expression of glucose transporter 1 (Glut 1) and fasting blood glucose in mouse. Eccentric contraction during running downhill found daily in activity such as down stairs and walking on tiptoe. Descend the stairs and walking on tiptoe are not easy to repeated, single, stable and universal, so that we purposed to replace it with additional insole in shoes for daily activity. The aim of this research was to investigate the effect of the additional shoe insole on fasting blood glucose and HbA1c. Method: This research using experimental pre and post test design with 12 subject female staff at Medical Faculty of Airlangga University for two weeks and the test was performed in three times. The blood was taken before and after using shoe insole. The shoe insole inclination designed into 50 and 100. All subjects used the shoe insole for a week. Result: The result research showed the fasting blood glucose and HbA1c on subject that use shoe insole lower than control group. The fasting blood glucose and HbA1c on subject that use shoe insole 100 has value p&lt;0,05. Discussion: Application of shoe insole lead to reduce the fasting blood glucose and HbA1c.Keywords: shoe insole, fasting blood glucose, HbA1c, diabetes, eccentric.   
PENGARUH EKSTRAK ETHANOL PROPOLIS TERHADAP KSPRESI PROTEIN CASPASE 8, APOPTOSIS, DAN PROLIFERASI PADA KULTUR SEL ADENOKARSINOMA KOLON (WiDr) Purwanto, Bambang; Kusnanto, Paulus; Poernomo, Gigih Rahmadanu
Biomedika Vol 10, No 1 (2018): Biomedika Februari 2018
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v10i1.5856

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Kanker kolorektal merupakan kanker terbanyak ketiga pada pria, kedua pada wanita, dan menjadi penyebab kematian keempat, sekitar 8% dari penyebab kematian karena kanker. Sebagian besar pasien kanker kolorektal didiagnosis dalam stadium yang sudah tidak dapat dioperasi. Propolis diketahui memiliki aktivitas anti kanker. Mekanisme anti kanker propolis melalui induksi apoptosis dan juga melalui penghambatan proliferasi dalam siklus sel. Penelitian ini bertujuan untuk mengkaji efek anti kanker ekstrak ethanol propolis (EEP) yang berasal dari Kerjo, Karanganyar, Indonesia pada kultur sel adenokarsinoma kolorektal (cell line WiDr) melalui pengaruhnya terhadap ekspresi protein Caspase 8, apoptosis dan proliferasi sel. Penelitian ini merupakan penelitian experimental laboratories, post test with control group design. Penelitian dilakukan pada kultur sel WiDr dengan perlakuan pemberian dosis ekstrak ethanol propolis, kontrol positif (5-FU), kombinasi ekstrak ethanol propolis dengan 5-FU, dan kontrol negatif (tanpa obat). Pengamatan ekspresi protein Caspase 8 dilakukan dengan metode imunositokimia, pengamatan apoptosis dilakukan dengan double staining menggunakan pewarnaan akridin oranye–etidium bromide, sedangkan pengamatan proliferasi menggunakan MTT assay dengan doubling time. Hasil Penelitian menunjukkan bahwa EEP cenderung menekan viabilitas sel WiDr dengan IC sebesar 140 µg/mL. EEP konsentrasi 70,140, 280 µg/mL mampu meningkatkan ekspresi protein Caspase 8 dan menginduksi apoptosis yang sebanding dengan peningkatan konsentrasi yang diberikan. EEP konsentrasi 70 µg/mL dapat menghambat proliferasi sel sebanding dengan EEP konsentrasi 140 dan 280 µg/Ml. Penelitian ini menunjukkan EEP mampu menekan viabilitas sel WiDr. Aktivitas ini kemungkinan terkait dengan kemampuannya dalam meningkatkan ekspresi protein Caspase 8 dan apoptosis sebanding dengan peningkatan konsentrasi yang diberikan. EEP pada konsentrasi terkecil yang diuji (70 µg/mL) mampu menghambat proliferasi pada sel WiDr sebanding dengan dosis yang lebih tinggi. Kata kunci: EEP, Caspase 8, apoptosis, proliferasi, cell line WiDr 
Penyakit Kimura Parotis Harsarapama, Pandu Putra; Dewi, Yussy Afriani; Purwanto, Bambang; Permana, Agung Dinasti
Jurnal Sistem Kesehatan Vol 2, No 2 (2016): Volume 2 Nomor 2 Desember 2016
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.085 KB) | DOI: 10.24198/jsk.v2i2.11263

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Penyakit kimura adalah kelainan inflamasi kronis, ditandai adanya limfadenopati atau massa jaringan lunak subkutan, tanpa nyeri, sering mengenai daerah kepala dan leher. Pertama kali dilaporkan di Cina pada 1937, disebut limfogranuloma hiperplastik eosinofilik. Tahun 1948, ditemukan keterlibatan komponen vaskular oleh Kimura, sehingga disebut Penyakit Kimura. Rasio perbandingan laki-laki dibandingkan wanita adalah 3.5-9 : 1. Insidensi usia adalah 20-30 tahun. Kasus Remaja laki-laki berusia 17 tahun datang ke Poliklinik THT-KL RSHS Bandung dengan keluhan benjolan leher sebelah kiri, daerah parotis, kelenjar getah bening level Ib dan II. Keluhan dirasakan sejak 2 bulan sebelumnya. Awalnya benjolan berukuran diameter 5 mm, membesar sampai sebesar 90 mm, mudah bergerak dan tidak nyeri pada perabaan. Metode Pemeriksaan laboratorium darah menunjukkan nilai eosinofil 22%, protein 9.4 gr/dL, dan serum IgE 3,8 mg/dL. Ultrasonografi leher menunjukkan massa solid yang dominan dengan bagian kistik di dalamnya yang mengobliterasi sebagian kelenjar parotis kiri. Pemeriksaan biospi jarum halus menunjukkan karsinoma parotis kemungkinan suatu mukoepidermoid. CT-Scan menunjukkan gambaran massa solid di daerah pre-parotis kiri dan lesi hipodens multipel bulat di daerah pre-parotis dan pre-aurikula kiri. Hasil Pemeriksaan histopatologis pasca operasi menunjukkan gambaran penyakit kimura parotis. Diskusi Pasca operasi, diberikan radioterapi dengan dosis 30 Gy, dilakukan kontrol selama satu tahun, tanpa terapi farmakologis, tidak ditemukan angka kekambuhan penyakit.Kata Kunci : Kimura, Parotis, Radioterapi
Co-Authors A.A. Ketut Agung Cahyawan W AA Subiyanto, AA Abdurachman Abdurachman Agung Dinasti Permana, Agung Dinasti Agustina Indri Hapsari, Agustina Indri Ahmad Abdullah Akbar, Idzam Kholid Ali Djamhuri Anandani, Esti Tantri Angguntur, Wayan Anindita, Rahma Arya H Dharmawan Assegaf, Aswin Rizal Atik Swandari, Atik Atmoko, Warigit Dri Ayu Kusuma Dewi Ayubi, Novadri Bambang Wirjatmadi Bogi Soeseno Budiyanti Wiboworini Damayanti Tinduh Deden Kamaludin Dedi Irwanto Dewi, Dinda Luciana Didik Prasetyo Diding Heri Prasetyo Dindy Samiadi Djaja Hendra Djoko Suryo Djoko Suryo Dwi Purwanti Dwi Putra, Kartika Wahyu Eman Sulaiman, Eman Endriatmo Soetarto Fatma Hetami Febrina, Irma Hadi Sabari Yunus Hari Setijono, Hari Hariyanto, Budhi HERAWATI, LILIK herdianty kusuma, herdianty Heri Dwi Santoso, Heri Dwi Herlina, Intan I Ketut Sudiana Ida Liana Tanjung Irwadi, Irfiansyah Istikomah, I La Ode Rabani Lina Lasminingrum Maria Johana Ari Widayanti Maryono, Sumardi Maryono, Suradi Melati Sudiro Merryana Adriani Muhammad Zainal Arifin, Muhammad Zainal Muhimatul Ifadah Nahdia Nur Nugroho, Ardi Setyo Nuha, Putri Ulin Nur Aini Setyawati Nur Inayah Pandu Putra Harsarapama, Pandu Putra Paulus Kusnanto Poernomo, Gigih Rahmadanu Pranadyan, Rizki Pratiwi, Wahyu Nur Priaminda, M Dodi F Priatmojo, Arif Suryo Rachmawati, Anindita Raden Mohammad Budiarto Rahmi Syarifatun Abidah, Rahmi Syarifatun Rejeki, Purwo Sri Rohaeni, Rohaeni Rosita, Hanna Eka Rosyidi, Mohamad Ikhwan Rudi Hartono Ruliyandari, Rochana Salamy, Nanda Fadhilah Witris Salimah, Kun Sally Mahdiani, Sally Saputro, Yosia Puri Sari, Gadis Meinar Seful Bahri Setiadi, Hafid Shinta Nurmasari Siahaan, Paulus Parholong Siti Aimah Sri Margana Sugiarto S Sukiman, Djoko Sulistiawati Sulistiawati Susanto, Tri Hardi Teti HS Madiadipoera Thaufiq S. Boesoirie Tonang Dwi Ardiyanto, Tonang Dwi Yuniarto, Haryono Yussy Afriani Dewi