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All Journal Medical Journal of Indonesia Jurnal Integrasi Kesehatan dan Sains Bandung Conference Series : Medical Science
Tety H. Rahim
Bagian Ilmu Kesehatan Telinga, Hidung, Tenggorok-Bedah Kepala Leher, RS Muhammadiyah/Fakultas Kedokteran, Universitas Islam Bandung
Humanities Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Clinical efficacy and tolerability of mometasone furoate nasal spray in perennial allergic rhinitis patients : an open multicentre study Darmansjah, Iwan; Setiawati, Arini; Sumarman, Iwin; Mulyarjo, Mulyarjo; Kasakeyan, Elise; Aroeman, Nur A.; Soemantri, Roestiniadi D.; Irawati, Nina; Rahim, Tety H.
Medical Journal of Indonesia Vol 11, No 2 (2002): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4340.094 KB) | DOI: 10.13181/mji.v11i2.55

Abstract

Mometasone furoate (MF) aqueous nasal spray has been shown to be effective and well-tolerated in the treatment of perennial allergic rhinitis (PAR). All of the sudies, however, have been conducted in Canada, UK, and Europe. Therefore, a bridging study is warranted in view of the different climatic conditions in tropical countries. To evaluate the clinical efficacy and tolerability of MF aqueous nasal spray in the treatment of PAR in a tropical country. This study was an open, non comparative, 4-week 3-centre trial in outpatients of 12 to 60 years with moderate to severe PAR of at least 2 years duration. Patients were allergic to at least one major PAR allergen, confirmed by skin prick test. They had total nasal symptom score (TNSS) of ≥ 6 and nasal congestion score (NCS) of ≥ 2 on ≥ 3 diary time points prior to baseline visit and at both screening and baseline visits. Eligible patients received MF aqueous nasal spray at baseline visit, and administered 200 µg mometasone every morning for 4 weeks. The primary clinical efficacy parameter was the mean percentage reduction of TNSS from baseline. Of 100 eligible patients, all completed this 4-week trial. The patient-evaluated TNSS (sum of the Last 3 mornings) decreased signiftcantly from baseline with a mean reduction of 60.9 % (p < 0.0001,) at week-2 and 73.6 % (p < 0.0001) at week-4. The mean reductions in physician-rated TNSS (61.7 % at week-2 and 77.8 % at week-4) were higher than those in the previous studies (43 % and 51 % at week-2, 52 % and 54 % at week-4). Similar trends were observed for nasal congestion score (NCS), other individual symptoms, total symptoms, and clinical efficacy rates. Evening symptoms were reduced similarly as morning symptoms There was no withdrawal due to adverse event. MF aqueous nasal spray, at a dose of 200 µg once daily in the morning for the treatment of moderate to severe PAR in a tropical country, was clinically effective with 24-hour control of PAR symptoms, and was well tolerated. (Med J Indones 2002; 11: 69-80)Keywords : mometasone furoate, nasal spray, perennial allergic rhinitis.
Systematic Review: Efektivitas Siprofloksasin Topikal pada Pengobatan Otitis Media Supuratif Kronik Anissha Fitry Oktavianita; Tety H Rahim; Lelly Yuniarti
Jurnal Integrasi Kesehatan dan Sains Vol 3, No 1 (2021): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v3i1.7363

Abstract

Otitis media supuratif kronik atau OMSK merupakan proses inflamasi kronik yang terjadi pada telinga bagian tengah yang diakibatkan oleh bakteri, ditandai dengan perforasi membran timpani serta ottorhoea yang terjadi secara terus menerus. Bakteri penyebab paling umum adalah Pseudomonas aeruginosa. Pengobatan OMSK dapat menggunakan antibiotik topikal siprofloksasin. Beberapa penelitian menunjukkan antibiotik topikal lebih efektif dibanding dengan antibiotik sistemik. Tujuan peneltian ini adalah menganalisis efektivitas siprofloksasin topikal pada pengobatan otitis media supuratif kronik. Penelitian ini merupakan systematic review dengan database yang digunakan adalah Google Scholar, Science Direct, Proquest, Springer Link, Cochrane Library, dan EBSCO HOST dengan jumlah artikel yang didapat sebanyak 599 artikel. Hasil skrining pada artikel yang sesuai dengan kriteria inklusi sebanyak 344 artikel dan kriteria eksklusi sebanyak 340 artikel. Setelah dilakukan telaah kritis, artikel yang di-review sebanyak empat artikel. Penelitian dilakukan pada periode Maret–Desember 2020. Hasil telaah dan analisis dari empat artikel menunjukkan bahwa siproflokasin topikal lebih efektif dibanding dengan topikal neomisin, framisetin gramisidin-deksametason (FGD), dan asam borik pada pengobatan otitis media supuratif kronik. Parameter kesembuhan gejala ottorhoea, perforasi membran timpani, serta kualitas pendengaran. Kesimpulan penelitian ini adalah siprofloksasin topikal efektif pada pengobatan otitis media supuratif kronik. Systematic Review:  Efectiveness of Topical Ciprofloxacin in the Treatment of Chronic Suppurative Otitis MediaChronic suppurative otitis media or CSOM is an chronic inflammatory process that occurs in the middle ear, which is caused by bacteria with perforation of the tympanic membrane and the presence of ottorhoea. The most common causative bacteria is Pseudomonas aeruginosa. Topical antibiotic using ciprofloxacin can be used to treat for CSOM. Several studies have shown topical antibiotic to be more effective than systemic antibiotics. The aim of this study was to analyze the effectiveness of ciprofloxacin in the treatment of chronic suppurative otitis media. The study was conducted using systematic review method and database used in this study were Google Scholar, Science Direct, Proquest, Springer Link, Cochrane Library, and EBSCO HOST with 599 articles of journals obtained. The screening result on articles in accordance with the inclusion citeria were 344 articles and the exclusion criteria were 340 articles. The results of critical appraisal as many 4 articles.The study was conducted during March–December 2020. The results of review dan analysis from 4 articles of each study, topical ciprofloxacin was more effective topical neomycin, framycetin gramicidin-dexamethasone (FGD), and boric acid in the treatment of chronic suppurative otitis media. The parameters for relieving of symptomatic symptoms, perforation of tympanic membrane, and hearing quality. The conclusion of this study is that ciprofloxacin topical is more effective in the treatment of chronic suppurative otitis media.
Hubungan Kepatuhan Penggunaan Earplug terhadap Keluhan Gangguan Pendengaran pada Pekerja PT Anugrah Bungo Lestari Fitria Hazmi Sholihah; Tety H. Rahim; Susan Fitriyana
Jurnal Integrasi Kesehatan dan Sains Vol 3, No 2 (2021): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v3i2.7392

Abstract

Paparan kebisingan di tempat kerja merupakan salah satu bahaya yang paling sering terjadi. Diperkirakan 22,4 juta pekerja di seluruh dunia terpapar kebisingan yang berpotensi menyebabkan gangguan pendengaran akibat bising. Gangguan pendengaran akibat bising dapat dicegah dengan memakai earplug. Penelitian ini bertujuan mengetahui hubungan kepatuhan penggunaan earplug dengan keluhan gangguan pendengaran pada karyawan PT Anugrah Bungo Lestari. Penelitian ini bersifat deskriptif analisis dengan metode cross-sectional. Variabel kepatuhan dan keluhan gangguan pendengaran diukur menggunakan kuesioner yang diisi oleh responden. Sampel yang diteliti adalah pekerja bagian mesin dengan sampel sebanyak 100 responden yang dipilih secara total sampling dan dilakukan uji chi-square sebagai uji hipotesis. Penelitian dilakukan pada bulan September–Desember 2020 di PT Anugrah Bungo Lestari, Kabupaten Bungo, Provinsi Jambi. Hasil penelitian ini menunjukkan sebanyak 80% pekerja PT Anugrah Bungo Lestari sudah patuh dalam menggunakan earplug. Terdapat 46% pekerja mengeluhkan gangguan pendengaran yang tidak mengganggu aktivitas, 16% pekerja mengalami keluhan gangguan pendengaran yang mengganggu aktivitas, sedangkan sisanya tidak mengeluhkan gangguan pendengaran (38%). Hasil uji pada pekerja yang tidak patuh menggunakan earplug terdapat keluhan gangguan pendengaran (p<0,001). Simpulan, terdapat hubungan penggunaan earplug dengan keluhan gangguan pendengaran.THE COMPLIANCE RELATIONSHIP OF USING EARPLUGS TO COMPLAINTS OF HEARING LOSS AMONG EMPLOYEES PT ANUGRAH BUNGO LESTARINoise exposure in the workplace is one of the most frequent hazards. An estimated 22.4 million workers worldwide are exposed to noise that potential to cause noise-induced hearing loss. Noise-induced hearing loss can prevent by wearing earplugs. This study aims to determine the relationship of compliance with the use of earplugs to complaints of hearing loss among employees of PT Anugrah Bungo Lestari. This research is descriptive-analytic with a cross-sectional design. The compliance and hearing loss complaints variables were measured using a questionnaire filled out by the respondents. The sample studied was 100 workers in the machine part chosen by total sampling and performed chi-square test as a hypothesis test. This research has conducted in September–December 2020 at PT Anugrah Bungo Lestari, Bungo regency, Jambi province. The results show that 80% of PT Anugrah Bungo Lestari's workers are obedient in using earplugs. There are 46% of workers complaining of hearing loss that does not interfere with activities, 16% of workers have complained of hearing loss that interferes with activities, while the rest do not complain of hearing loss (38%). The test results in workers who did not comply with using earplugs had complaints of hearing loss (p<0.001). In conclusion, there is a relationship between the use of earplugs and complaints of hearing loss.
Hubungan antara Kecanduan Mengakses Internet dengan Prestasi Belajar pada Siswa di SMAN 1 Sumberjaya Kabupaten Lampung Barat Tia Siti Roila; M. Nurhalim Shahib; Tety H Rahim
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.773

Abstract

Abstract. Introduction: The Covid-19 pandemic has caused many activities to be carried out online, making the intensity of internet use increase. Uncontrolled use of the internet triggers internet addiction which can have an impact depending on its use in a positive or negative direction. This study aims to determine the relationship between addiction to internet access and student achievement at SMAN 1 Sumberjaya, West Lampung. Methods: This research is quantitative, analytic observational with astudy design cross sectional with research samples of students of SMAN 1 Sumberjaya, West Lampung in class XI and XII of the 2020-2021 school year. The results of this study have been statistically analyzed with the Chi-Square Test. Results: The results showed that the level of internet addiction was mostly in the moderate category 57.7% with the student achievement level mostly included in the good category 92.5%. Chi-Square Test showed a significant relationship between addiction to internet access and learning achievement, with a P value (P = 0.000). The same results also showed that there was a relationship between the incidence of internet addiction and learning achievement, with a P value (P = 0.0001). Conclusion: The conclusion of this study is that the level of internet addiction in the moderate category has a positive impact on student achievement at SMAN 1 Sumberjaya, West Lampung. Abstrak. Pendahuluan: Kondisi pandemi covid-19 menyebabkan banyak kegiatan dilakukan secara daring membuat intensitas penggunaan internet meningkat. Penggunaan internet yang tidak terkontrol memicu terjadinya kecanduan internet yang mampu memberikan suatu dampak tergantung dari penggunaanya kearah positif atau negatif. Penelitian ini bertujuan untuk mengetahui hubungan antara kecanduan mengakses internet dengan prestasi belajar pada siswa di SMAN 1 Sumberjaya, Lampung Barat. Metode: Penelitian ini bersifat kuantitatif, observasional analitik dengan rancangan studi cross sectional dengan sampel penelitian siswa SMAN 1 Sumberjaya, Lampung Barat kelas XI dan XII tahun ajaran 2020-2021. Hasil dari penelitian ini telah dianalisis secara statistik dengan Chi-Square Test. Hasil: Hasil penelitian menunjukkan bahwa tingkat kecanduan internet sebagian besar termasuk kedalam kategori sedang 57,7% dengan tingkat prestasi belajar siswa sebagian besar termasuk kedalam kategori baik 92,5%. Chi-Square Test menunjukkan adanya hubungan yang signifikan antara kecanduan mengakses internet dengan prestasi belajar, dengan nilai P (P=0,000). Hasil yang sama didapatkan juga bahwa terdapat hubungan antara kejadian kecanduan internet dengan prestasi belajar, dengan nilai P (P=0,0001). Kesimpulan: Kesimpulan penelitian ini adalah tingkat kecanduan internet dengan kategori sedang memberikan dampak kearah yang bersifat positif terhadap prestasi belajar siswa SMAN 1 Sumberjaya, Lampung Barat
Scoping Review: Analisis Pengaruh Rokok terhadap Faktor Risiko Terjadinya Karsinoma Nasofaring Putri Nadiah Irfatul Aini; Abdul Hadi Hassan; Tety H Rahim
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.1788

Abstract

Abstract. Nasopharyngeal carcinoma is the most common malignancy among head and neck carcinomas. Nasopharyngeal carcinoma is more common in men than women. Nasopharyngeal carcinoma has several relevant risk factors, such as lifestyle, socioeconomic and alcohol consumption habits. The purpose of this study was to assess the effect of smoking on the risk of nasopharyngeal carcinoma. This research uses the scoping review method . This study takes several scientific articles that have met the eligibility requirements ( eligible ). The scientific articles were taken from three databases, namely PubMed, Springer Link , and Science Direct. The initial search found 1,977 articles. After being selected using the inclusion criteria, 284 articles were obtained. Then from the 248 articles, the selection was carried out again until they were in accordance with the PICOS criteria, then five articles were obtained that matched the feasibility of the title of this study. The conclusion from this analysis is that there is a content in cigarettes (nicotine) that can affect several mechanisms of cancer cell formation. In addition, the socioeconomic role is also quite influential in the occurrence of nasopharyngeal carcinoma. Abstrak. Karsinoma nasofaring adalah suatu keganasan tersering di antara karsinoma kepala dan leher. Karsinoma nasofaring sering terjadi pada laki – laki di bandingkan perempuan. Karsinoma nasofaring memiliki beberapa faktor risiko yang relevan, seperti gaya hidup, sosial ekonomi dan kebiasaan mengkonsumsi alkohol. Tujuan dari penelitian ini yaitu untuk menilai pengaruh merokok terhadap risiko terjadinya karsinoma nasofaring. Penelitian ini menggunakan metode scoping review. Penelitian ini mengambil beberapa artikel ilmiah yang telah memenuhi syarat kelayakan (eligible). Artikel – artikel ilmiah tersebut di ambil dari tiga databased yaitu PubMed, Springer Link, dan Science Direct. Pencarian awal didapatkan sebanyak 1.977 artikel. Setelah di lakukan pemilihan dengan menggunakan kriteria inklusi di dapatkan artikel sebanyak 284 artikel. Lalu dari 248 artikel tersebut dilakukan seleksi lagi hingga sesuai dengan kriteria PICOS, maka didapatkan lima artikel yang sesuai dengan kelayakan judul penelitian ini. Kesimpulan dari analisis ini yaitu terdapat kandungan pada rokok (nikotin) yang dapat mempengaruhi beberapa mekanisme pembentukan sel kanker. Selain itu, peran sosioekonomi juga cukup mempengaruhi terjadinya karsinoma nasofaring.
Co-Authors Abdul Hadi Hassan Anissha Fitry Oktavianita Arini Setiawati Elise Kasakeyan Fitria Hazmi Sholihah Iwan Darmansjah Iwin Sumarman Lelly Yuniarti M. Nurhalim Shahib Mulyarjo Mulyarjo Nina Irawati Nur A. Aroeman Putri Nadiah Irfatul Aini Roestiniadi D. Soemantri Susan Fitriyana Tia Siti Roila