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ANALISIS KUALITAS AIR TANAH BERDASARKAN JENIS KANDUNGAN KIMIA FISIK AIR PADA AKUIFER BEBAS CEKUNGAN AIR TANAH (CAT) PALU DI KABUPATEN SIGI PROVINSI SULAWESI TENGAH Rachman, Arif; Yuwanto, Sapto Heru; Bahar, Hendra
Prosiding Seminar Teknologi Kebumian dan Kelautan Vol 2, No 1 (2020)
Publisher : Prosiding Seminar Teknologi Kebumian dan Kelautan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1924.645 KB)

Abstract

Cekungan Air Tanah (CAT) Palu merupakan salah satu Cekungan Air Tanah (CAT) yang yang meliputi kota Palu dan kabupaten Sigi, Sulawesi Tengah. Cekungan Air Tanah (CAT) Palu memiliki luas sebesar 313 km2 dan merupakan Cekungan Air Tanah yang digunakan oleh masayarakat untuk keperluan sehari-hari. Cekungan Air Tanah Palu tersusun atas endapan permukaan dan batuan sedimen sehingga dapat menjadi akuifer yang baik dalam menyimpan dan meloloskan air tanah. Penelitian ini dilakukan dengan tujuan untuk mengetahui kondisi geologi dan hidrogeologi Cekungan Air Tanah (CAT) Palu, serta mengetahui kualitas air tanahnya. Metode yang digunakan dalam penelitian ini yaitu pemetaan geologi permukaan dan analisis laboratorium. Pemetaan permukaan dilakukan untuk mengetahui kondisi geologi daerah penelitian, sedangkan analisis laboratorium untuk mengetahui kandungan kimia air tanah. Berdasarkan hasil penelitan dan pembahasan daerah penelitian terdiri atas empat (4) satuan geomorfologi berupa dataran yang terangkat (D6), pegunungan tersayat kuat berlereng curam (S4), perbukitan tersayat kuat berlereng curam (S3), dan danau (F2). Daerah penelitian tersusun atas satuan batupasir karbonatan dan endapan permukaan. Air tanah pada daerah penelitian terbagi atas tiga (3) jenis yaitu Magnesium Bicarbonate, Mixed, dan Sodium Chloride. Air tanah pada daerah penelitian secara umum dapat dikonsumsi, kecuali air pada mata air panas yang memiliki pH yang cukup tinggi.
THE EFFECT OF CONDITIONED-MEDIUM HUMAN ADIPOSE-DERIVED MESENCHYMAL STEM CELL IN APOPTOSIS OF BLADDER CANCER CELLS Mawdudi, Ari Alauddin; Hidayatullah, Furqan; Bachtiar, Indra; Rachman, Arif; Putri, Indri Lakhsmi; Castiglione, Fabio; Djatisoesanto, Wahjoe; Hakim, Lukman
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.653

Abstract

Objective: To determine the effect of conditioned medium human Adipose-Derived Mesenchymal Stem Cells (CM-hADMSC) on apoptosis of urothelial bladder cancer cells. Material & Methods: Bladder (5637) cancer cell lines cultured in conditioned media harvested from human adipose-derived mesenchymal stem cells (hADMSC). Flow cytometry tests were carried out using the Flowcytometry Acquisition cell sorting (FACS) Calibur to measure apoptosis. Results: There was a significant difference in the percentage of late apoptosis in the group receiving culture medium treatment: CM-hADMSC 1: 1 to the entire study group. Further analysis revealed no difference in the average percentage of late apoptosis in groups exposed to culture medium: CM-hADMSC 1: 2 and culture medium: CM-hADMSC 1: 4 (p> 0.05). Conclusion: CM-hADMSC at a 1: 1 dose concentration to culture medium obtain a significant increase of apoptosis in bladder cancer cells.
THE EFFECT OF CONDITIONED MEDIUM ADIPOSE DERIVED MESENCHYMAL STEM CELLS IN UROTHELIAL CARCINOMA CULTURE CELLS VIABILITY Prasetyo, Suryo; Hidayatullah, Furqan; Bachtiar, Indra; Rachman, Arif; Putri, Indri Lakhsmi; Castiglione, Fabio; Soebadi, Doddy M.; Hakim, Lukman
Indonesian Journal of Urology Vol 28 No 1 (2021)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v28i1.654

Abstract

Objective: This study aimed to gives a perspective in CM-ADMSCs effect in urothelial bladder cancer viability. Material & Methods: Human bladder cell carcinoma type 5637 was used as the subject of this in vitro study. This study contains four different groups: untreated control group, Culture medium: hADMSCs with 1:1, 1:2, and 1:4 concentration group. Each group consists of 6 replications to prevent bias of the study. Viability was determined with MTT assay methods and evaluation performed after 48 h exposure of conditioned medium. Results: A post hoc test was conducted to analyze the data. The 5637 bladder cancer cell line demonstrated significantly decreased viability after exposure to culture medium: CM-hADMSCs 1:1 (p: 0.002) compared to the negative control group, but there are no significant differences in viability between the control groups with groups that were exposed to culture medium: CM-hADMSCs 1:2 and culture medium: CM-hADMSCs 1:4 with p: 0.480 and p: 0.060 respectively. Conclusion: Decreased viability of urothelial bladder cancer cells after exposure to CM-hADMSCs occurs at a concentration of 1:1 and Dosage addition more than 1:1 concentration doesn’t give any advantages.
Peningkatan Ekonomi Kreatif Budidaya Pembenihan Lele dengan Probiotik Mergosubhara Rachman, Arif; Terubus, Terubus; Munawaroh, Siti
Jurnal Abdimas Vol 25, No 1 (2021): June 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/abdimas.v25i1.23352

Abstract

Mergosari village of Tarik sub-district of Sidoarjo Regency has the potential to increase the creative economy in catfish hatchery cultivation by empowering the community in increasing food security for protein and increasing the economy. Catfish is one of Indonesia's food security commodities which is divided into the hatchery and enlargement business segments of catfish. The hatchery segment is very important in the agribusiness subsystem of the catfish farming business which determines the availability of catfish supply at the enlargement segment stage. The use of probiotics for hatchery farmers has not been done which results in a risk of decreasing production with a reduced amount of catfish seeds. Probiotics have been shown to have an important role in fish farming (4). KKM PPM - TEMATIK 2020 Program Ubhara Surabaya Group 039 on improving the creative economy of Mergosubhara probiotic catfish hatchery production can have a major impact on increasing the national food security of protein and improving the economy of the village through the potential of villages in Mergosari Village, Tarik District, Sidoarjo Regency.