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All Journal Jurnal Ilmiah Farmasi e-Journal Pustaka Kesehatan Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Global Medical and Health Communication Jurnal Farmasi Sains dan Komunitas (JFSK) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Warta Pengabdian Jurnal Farmasi Indonesia

Ema Rachmawati

Fakultas Farmasi Universitas Jember

Author-ID : 353970

Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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A SURVEY OF ANTIBIOTICS PURCHASED WITHOUT PRESCRIPTION AMONG NON-HEALTH SCIENCE STUDENTS IN JEMBER, INDONESIA Antonius Nugraha Widhi Pratama; Anis Rohmawati; Ema Rachmawati
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 15, No 1 (2018)
Publisher : Sanata Dharma University

Previous research showed that self-medication practice with antibiotics is widespread in developing countries and tertiary students are among these consumers. This study aimed to estimate the prevalence of the use of antibiotics without prescription among non-health science students in Jember and to identify the sources of non-prescription antibiotics. This cross-sectional survey was conducted between April and June 2016 in all non-health science faculties of Universitas Jember. A questionnaire containing four main short questions about antibiotics use and questions related to socio-demographic information was distributed to students who gave consent. A number of 130 (58.5%) respondents admitted to ever acquire antibiotics without the presence of a physician prescription. Self-medication with antibiotics tended to be done by students from rural areas (p=0.04) and without health insurance (p=0.04). The sources of non-prescription antibiotics vary, but pharmacy was the most frequently cited to be the source (n=82; 46.3%). This study showed that the use of antibiotics without prescription among non-health science students and the sale of antibiotics without prescription among pharmacies in Jember are prevalent. Real responses from the government, relevant health professional associations, and education institutions to intervene these problems are significantly needed.

Potensi Penggunaan Obat yang Tidak Tepat pada Peresepan Pasien Geriatri Rawat Jalan di RSD dr. Soebandi Jember Berdasarkan Beers Criteria (Potentially Inappropriate Medication Based on Beers Criteria in Geriatric Outpatients of dr. Soebandi District Hosp Yeni Rahmawati Negara; Afifah Machlaurin; Ema Rachmawati
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Inappropriate medication in geriatric is a serious problem because of its high morbidity, mortality, and healthcare costs. Beers Criteria 2012 is the compilation drugs that potentially inappropriate on geriatric patients. The objective of this study was to observe the percentage of inappropriate medication in geriatric outpatients prescription.This study used observational descriptive and retrospective design. The study showed that 69 patients (18.30%) from 377 patients prescribed with 92 inappropriate medication, 20 medication with strong and high quality evidence to be avoided based on Beers Criteria 2012. Amitriptyline was the most prescribed potentially inappropriate agents of 17 events. Keywords: geriatric, beers criteria,outpatients

Pengaruh Ekstrak Metanol Daun Kayu Kuning (Arcangelisia flava (L.) Merr.) terhadap Kadar Kolesterol Total dan Trigliserida Tikus Hiperlipidemia (The Influence of Methanol Extract of Yellow Root (Arcangelisia flava (L.) Merr.) Leaves on Total Cholesterol Putri Eka Maryani; Evi Umayah Ulfa; Ema Rachmawati
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Hyperlipidemia is heterogeneous disorder that characterized by elevated levels of total cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL), triglyceride, and decreased levels of high density lipoprotein (HDL). The aim of this study was to determine the ability of methanol extract of leaves of Arcangelisia flava to decrease total cholesterol and triglyceride in some variations of dosage. Five groups experimental animal (each consisting of 4 rats) which have been induced by high fat and fructose diet for 45 days, followed by oral treatment of extract at a dose of 250 mg/kg BW, 500 mg/kg BW, 750 mg/kg BW, simvastatin 0.36 mg/200 g BW (control (+)), and CMC Na 1% (control (-)) for 7 days. The blood was taken on day 8, then was measured the total cholesterol and triglyceride. The test results showed that extract could decrease total cholesterol and triglyceride in line with increasing doses. According to ANOVA, there are significant differences between treatment groups (p

Hubungan antara Tingkat Pengetahuan Pasien dan Pengawas Menelan Obat (PMO) dengan Kepatuhan Pasien Tuberkulosis di Puskesmas Kabupaten Jember Antonius Nugraha Widhi Pratama; Amelya Prastica Rahayu Aliong; Nili Sufianti; Ema Rachmawati
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7570

Tuberculosis (TB) is an infectious disease that mostly affects developing countries. In Indonesia, TB incidence increases every year due to patient inadherence to the standard DOTS therapy. The TB patients inadherence can be associated with poor knowledge among patients and treatment observers. This cross-sectional research aimed to explore the correlation between knowledge level of TB patients and their treatment observers and patient adherence. Purposive sampling technique was used to collect data from 65 respondents from their primary health centers in Jember Regency, East Java. Knowledge of the respondents was evaluated using a 16 items questionnaire and patient adherence was assesed using the translated version of morisky medication adherence scale-8 (MMAS-8) questionnaire. The Spearman Rho correlation test resulted in p value of 0,043 between patients knowledge and patients adherence. Statistically significant correlation was also found between the knowledge of treatment observers and TB patients adherence (p= 0,015). These results suggested the needs to improve knowledge about TB not only for TB patients, but also their treatment observers. Keywords: TB patient, treatment observer, knowledge, compliance

Identifikasi Drug Related Problems (DRPs) pada Terapi Diabetes Melitus Tipe 2 di Instalasi Rawat Inap RSD dr. Soebandi Jember Periode Tahun 2015 (Identification of Drug Related Problems (DRPs) for Type 2 Diabetes Mellitus Therapy in Hospitalized Patients Khoirotun Nazilah; Ema Rachmawati; Prihwanto Budi Subagijo
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i3.5891

Diabetes mellitus (DM) is a degenerative disease which causes various complications that require patients to use polypharmacy. The use of polypharmacy has been reported to be one of the causes of drug related problems (DRPs). DRPs are unexpected events related to the treatment undergone by the patient. This study aimed to avoid DRPs so that patients could receive the best treatment. This research used total sampling method and conducted retrospectively using medical records of patients with type 2 diabetes which were hospitalized in RSD dr. Soebandi Jember in 2015. As many as 15 patients (25%) of 60 patients experiencing DRPs were included in the six criteria of DRPs. This criteria included unnecessary drug therapy found in 1 patient (6,67%), need for additional drug therapy found in 1 patient (6.67%), ineffective drug found in 4 patients (26,67%) and drug interactions found in 10 patients (66.67%). Eventhough too high dosage and too low dosage was not found in all patient samples. Keywords: type 2 diabetes mellitus, drug related problems (DRPs), antidiabetic, hospitalized

Studi Penggunaan Obat pada Pasien Osteoartritis Usia Lanjut di Instalasi Rawat Jalan Rumah Sakit dr. H Koesnadi Bondowoso Tahun 2013 Ema Rachmawati; Putu Setia Pratama; Afifah Machlaurin
Pustaka Kesehatan Vol 6 No 3 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i3.9868

Osteoarthritis (OA) is a degenerative bone disease that begin by loss of articulary cartilage (joint). The disease most commonly affects the elder or adult people. Elderly people experiencing degenerative processes in which decreasing organ function. The organ degeneration causes several diseases resulting the patients to receive multi drug for the treatment and causing polypharmacy, thus will increase the risk of drug interactions. This study was conducted to determine the treatment for osteoarthritis and drug interactions that occur in patients with osteoarthritis. The method used was total sampling using the descriptive-retrospective approach. The sample was elderly osteoarthritis patients in outpatient installation which were treated in RSD dr. H Koesnadi Bondowoso during January to December 2013. In this study we found that the main treatment for osteoarthritis was non steroidal anti inflammatory drug (NSAID) that use to relief pain. From 108 samples of elderly osteoarthritis patients, we found that 17 patients (15.74%) indicating the potential for drug interactions. Keywords: osteoarthritis, outpatient age above 60 years, NSAID, drug interaction

Pengaruh Pemberian Edukasi Menggunakan Buku Saku Bergambar dan Berbahasa Madura terhadap Tingkat Pengetahuan Penderita dan Pengawas Menelan Obat Tuberkulosis Paru (The Effect of A Pictorial Booklet with Madurese Language on Level of Knowledge among Tuber Lailatul Maghfiroh; Antonius Nugraha Widhi Pratama; Ema Rachmawati
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i3.5892

Tuberculosis (TB) has become one of major health problems. Successful treatment of pulmonary TB is determined by patient adherence. One of the factors that influences poor patient adherence is the lack of knowledge in TB among patients and treatment observer. Improving this knowledge is therefore necessary. This study was conducted with the aim to analyze the effect of education using a booklet with pictures and Madurese language on the TB knowledge level of patients and treatment observer. This study used a quasi-experimental study design with one group pre-test and post-test. This research was conducted in Kaliwates, Patrang, and Mayang health centers, Jember Regency. The level of knowledge was evaluated using a 16 item questionnaire at the time before the booklet was given and 1-2 weeks after. The result of paired T-test analysis showed a statistically significant increase (p<0.001) of TB knowledge level before (10.18 ± 1.781) and after (11.88 ± 1.686) the education using the booklet. In conclusion, the use of a booklet containing illustrated pictures and local language may improve the level of knowledge of TB patients and their treatment observer. Keywords: tuberculosis, tuberculosis treatment observer, health education, booklet, Madurese language

Mothers levels of knowledge of self-medication of diarrhea for under-five children in Kaliwates, Jember Inasa Hazrina; Sinta Rachmawati; Ema Rachmawati
Media Farmasi: Jurnal Ilmu Farmasi Vol 19, No 1: March 2022
Publisher : Universitas Ahmad Dahlan

Diarrhea is the fifth-highest cause of death in under-five children worldwide, and it is preventable. Mild diarrhea can be treated by self-medication. In this case, mothers have an important role in handling diarrhea in children. This study aims to determine the level of mothers knowledge self-medication in diarrhea to treat under-five children in Kaliwates District, Jember. This study used an observational study design with a cross-sectional approach. The data were collected in 11 integrated healthcare centers in 3 community health centers in Kaliwates District. The research respondents were 348 mothers. Before being distributed, the questionnaire was tested to explore its validity and reliability. This questionnaire was employed to assess the mothers' level of knowledge of self-medication for infants. The data were analyzed statistically using the Chi-square test and Fisher Exact. The results showed that the mothers have a sufficient of knowledge level self-treatment of diarrhea for infants. There is a significant relationship between age, recent education, employment, family income, number of children, number of adult family members, information sources, and educational experience (p < 0.05). This study suggests the importance of providing interventions to improve mothers knowledge of self-medication of diarrhea.

Uji Toksisitas Subkronis Ekstrak Kayu Kuning (Arcangelisia flava Merr) terhadap Hepar dan Ginjal Ema Rachmawati; Evi Umayah Ulfa
Global Medical & Health Communication (GMHC) Vol 6, No 1 (2018)
Publisher : Universitas Islam Bandung

Kayu kuning (Arcangelisia flava Merr) merupakan tanaman asli Indonesia yang banyak mengandung alkaloid berberin dan flavonoid. Tanaman ini telah terbukti memiliki aktivitas sebagai antioksidan, antibakteri, antikanker, dan antihiperlipidemia, namun belum diketahui pengaruhnya terhadap hepar dan ginjal sehingga penelitian ini bertujuan mengetahui pengaruh ekstrak A. flava terhadap parameter biokimia hepar, histopatologi hepar, dan histopatologi ginjal tikus. Penelitian dilakukan di Laboratorium Biomedik, Fakultas Farmasi Universitas Jember pada bulan Mei–Agustus 2016. Sebanyak 40 ekor tikus jantan berusia 2–3 bulan dengan bobot 200–300 gram dibagi menjadi 4 kelompok. Kelompok kontrol hanya diberi sodium-carboxymethyl cellulose (CMC-Na) 1%, sedangkan kelompok perlakukan diberi ekstrak A. flava dosis 250, 500, dan 750 mg/kgBB per oral selama 28 hari. Pada hari ke-28, dilakukan penentuan kadar SGOT, SGPT, serta pengamatan histopatologi hepar dan ginjal. Nilai SGPT menunjukkan tidak berbeda bermakna antara kelompok kontrol dan kelompok perlakukan (p<0,05). Hasil pengamatan histopatologi hepar menunjukkan pemberian ekstrak A. flava dosis 250, 500, dan 750 mg/kgBB per oral menyebabkan kongesti pembuluh darah hepar, namun tidak mengakibatkan nekrosis. Pengamatan histopatologi pada ginjal tidak terdapat peradangan, namun terdapat perdarahan sedikit pada glomerulus dan interstitial. Simpulan, pemberian ekstrak A. flava dosis 250, 500, 750 mg/kgBB selama 28 hari tidak mengakibatkan kerusakan hepar dan ginjal. SUBCHRONIC TOXICITY TEST OF YELLOW ROOT EXTRACT (ARCANGELISIA FLAVA MERR) ON HEPAR AND RENALKayu kuning (Arcangelisia flava Merr) is one of Indonesian herbal plant which contain berberine alkaloid and flavonoids. This plant has been proven as antioxidant, antibacterial, anticancer, antihiperlipidemic and antidiabetes. However, the effect of A. flava extract on hepar and renal has not been studied yet. Accordingly, the objective of this study was to evaluate the effect of A. flava extracts towards chemical parameters of hepar, histopathology of hepar and renal rats. This research was conducted in The Biomedic Laboratory, Faculty of Pharmacy of Universitas Jember on May to August 2016. Forty Wistar male rats aged 2–3 moths, weighed 200–300 grams were divided into four groups. Control groups were only given sodium-carboxymethyl cellulose (CMC-Na) 1% orally while tretment groups were given A. flava extracts at dose 250, 500, and 750 mg/kgBW orally for 28 days. On the day 28, the SGOT, SGPT were measured and histopathology of liver and renal were observed. The result of this research showed that SGPT value of control group and treatment group were not significantly different (p<0.05). Histopathogical evaluation of liver showed that oral administration of A. flava extract at dose 250, 500, and 750 mg/kgBW caused congestion of liver blood vessel, but the liver cell did not experience necrosis. Histopathogical observation on renal showed that there was no inflamation but there was a small bleeding in glomerolus and interstitial. In conclusion, the administration of A. flava extract at doze 250, 500 and 750 mg/kbBW for 28 days do not affect the liver and the renal.

Pengembangan Produk Penyedap Rasa dan Tepung Jamur Tiram di Desa Penambangan dan Kelurahan Dabasah Kabupaten Bondowoso Indah Yulia Ningsih; Ika Barokah Suryaningsih; Ema Rachmawati
Warta Pengabdian Vol 12 No 3 (2018): Warta Pengabdian
Publisher : LP2M Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/wrtp.v12i3.8632

Jamur tiram merupakan salah satu hasil pertanian yang diminati masyarakat. Banyaknya petani jamur tiram menyebabkan sulitnya harga komoditas ini bertahan bila seringkali terjadi panen raya secara bersamaan. Di Kabupaten Bondowoso, tepatnya di Desa Pertambangan dan Kelurahan Dabasah telah dilakukan budidaya oleh kelompok petani. Namun, para petani jamur tiram tersebut tidak memiliki pengetahuan, dan keterampilan untuk menghasilkan produk olahan jamur tiram yang tahan lama dan memiliki nilai jual yang tinggi. Oleh karena itu, pada kegiatan pengabdian ini dilakukan penyuluhan dan pelatihan mengenai pembuatan dan pengemasan produk olahan jamur tiram dalam bentuk penyedap rasa dan tepung jamur tiram. Adanya diversifikasi produk berperan dalam meningkatkan nilai tambah komoditas jamur tiram, sehingga dapat meningkatkan pendapatan para petani. Kata Kunci: Jamur Tiram, Penyedap Rasa, Tepung Jamur, Pengembangan Produk

Co-Authors Afifah Machlaurin Afifah Machlaurin Afifah Machlaurin, Afifah Agnes Jovanka Amelia Windi Astutik Amelya Prastica Rahayu Aliong Anis Rohmawati Antonius Nugraha Widhi Pratama Antonius Nugraha Widhi Pratama Antonius Nugraha Widhi Pratama Dewi Khurmi Masito Dhea Nanda Aliefia Dhita Evi Aryani Diana Holidah Evi Umayah Ulfa Fransiska Maria C. Fransiska Maria Christianty Ika Barokah Suryaningsih Ika Norcahyanti Inasa Hazrina Indah Yulia Ningsih Khoirotun Nazilah Lailatul Maghfiroh Mohamad Nor Zaenudin Nili Sufianti Ninda Titis Ainorrochma Prihwanto Budi Subagijo Putri Eka Maryani Putu Setia Pratama Sinta Rachmawati Sinta Rachmawati Yeni Rahmawati Negara

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