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All Journal Majalah Kedokteran Bandung Global Medical and Health Communication ABDIMAS: Jurnal Pengabdian Masyarakat Jurnal Integrasi Kesehatan dan Sains JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Bandung Conference Series : Medical Science
Santun Bhekti Rahimah
Department Of Pharmacology, Faculty Of Medicine, Universitas Islam Bandung, Bandung
Humanities Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Potensi Interaksi Obat Antituberkulosis dan Anti Diabetes terhadap Efek Samping Obat pada Pasien Tuberkulosis-Diabetes Melitus di RSUD Al-Ihsan Bandung Rahma Ratu Halima; Santun Bhekti Rahimah; Asep Saefulloh; Yuke Andriane; Endang Suherian
Jurnal Integrasi Kesehatan dan Sains Vol 1, No 1 (2019): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v1i1.4323

Abstract

Pengobatan tuberkulosis (TB) dengan diabetes melitus (DM) pada pasien TB-DM membutuhkan waktu yang cukup lama dan beragam sehingga memiliki risiko tinggi menyebabkan potensi interaksi obat  dan menimbulkan efek samping obat. Penelitian ini bertujuan mengetahui hubungan potensi interaksi obat antituberkulosis dengan obat antidiabetes pada pasien TB dengan DM di Poli DOTS RSUD Al-Ihsan pada periode April–Mei 2018. Penelitian ini dilakukan dengan metode analitik observasional menggunakan pendekatan cross-sectional, pengambilan data obat yang terdapat pada rekam medik dan kuesioner yang telah dilakukan uji validitas dan uji reliabilitas. Data potensi interaksi obat diolah dengan memasukkan data obat yang dikonsumsi pasien menggunakan software pada Lexi-Interact. Subjek berjumlah 30 responden dipilih secara total sampling. Hasil penelitian menunjukkan frekuensi tertinggi potensi interaksi obat antituberkulosis-obat antidiabetes pada derajat berat sejumlah 12 dari 30 pasien. Efek samping yang terjadi pada pasien dengan frekuensi tertinggi adalah derajat ringan sejumlah 10 dari 30 pasien. Analisis dengan uji chi-square tidak memiliki nilai kemaknaan antara potensi interaksi obat dan efek samping obat (p=0,146). Simpulan, tidak terdapat hubungan potensi interaksi  obat dengan efek samping yang timbul pada pasien TB dengan DM di Poli DOTS RSUD Al-Ihsan periode April–Mei 2018. POTENTIAL INTERACTIONS BETWEEN ANTI TUBERCULOSIS DRUG AND ANTI DIABETES DRUG WITH SIDE EFFECTS ON TUBERCULOSIS-DIABETES MELLITUS PATIENTS IN RSUD AL-IHSAN BANDUNGThe medication of tuberculosis (TB) with diabetes mellitus (DM) on TB-DM patients requires quiet a long and diverse time, so it has a high risk to potentially causing a medicine interaction and produce side effects. The research aimed to know the relation of potential interactions between anti tuberculosis medicine and anti diabetes drug with side effects on TB-DM patients in Directly Observed Treatment Short-course (DOTS) outpatient clinic of RSUD Al-Ihsan Bandung in April–May 2018. This research was done by cross sectional approach method by taking the drug data in the medical records and questionnaires which have been tested for validity and reliability. Data of potential drug interactions is processed by entering data of drug consumed by patient using software on Lexi-Interact. The subjects were 30 respondents, selected by total sampling. The results showed the highest frequency of potential anti-tuberculosis drug anti-diabetic drug interactions on severe degree 12 of 30 patients. The results also showed that the side effects occurring in patients with highest frequency were mild degrees of 10 of 30 patients. The analysis obtained by chi square test between potential drug interaction with side effect of drug is not having any meaning value with (p=0.146).  In conclusion, there is no relation between potential drug interaction and side effect on TB-DM patients in Directly Observed Treatment Short-course (DOTS) outpatient clinic of RSUD Al-Ihsan Bandung in April–May 2018.
Scoping Review: Pengaruh Bensin terhadap Peningkatan Kadar LDL pada Plasma Darah Tikus Yola Noveraz Nasa; Nugraha Sutadipura; Santun Bhekti Rahimah
Jurnal Integrasi Kesehatan dan Sains Vol 3, No 1 (2021): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v3i1.7382

Abstract

Konsumsi bensin sejak tahun 2000 sampai 2014 meningkat seiring dengan peningkatan jumlah kendaraan bermotor setiap tahun. Bensin memiliki dampak negatif terhadap lingkungan berupa polusi dan terhadap kesehatan seperti gangguan paru, ginjal, penyakit kulit, serta perubahan profil lipid berupa peningkatan kadar low-density lipoprotein (LDL) yang dapat meningkatkan angka kejadian penyakit jantung koroner dan sindrom metabolik. Tujuan penelitian mengetahui pengaruh paparan bensin terhadap kadar LDL pada plasma darah manusia yang dimulai dengan kajian terhadap hewan coba. Metode penelitian yang digunakan yaitu deskriptif dengan prosedur scoping review dengan cara mengidentifikasi, menganalisis dan mengevaluasi karya ilmiah sesuai dengan kriteria inklusi dan eksklusi serta diskrining menggunakan kriteria kelayakan (Eligibility criteria). Hasil penelitian didapatkan sepuluh artikel dari jumlah awal 10.486 artikel yang ditemukan dari kata kunci. Sepuluh artikel yang sesuai dengan PICO (Population: tikus; Intervention: bensin, lead atau benzene;  Comparison: tikus yang tidak dipaparkan bensin, lead atau benzene; Outcome: kadar LDL pada plasma darah) menunjukkan peningkatan kadar LDL plasma pada kelompok tikus yang diberi paparan bensin, timbal atau benzena daripada kelompok kontrol. Hal tersebut diakibatkan stres oksidatif dari induksi lead atau benzene yang menekan aktivitas antioksidan dan meningkatkan reactive oxygen species di tubuh sehingga terjadi cidera hepar dan metabolisme lipoproteinpun terganggu. Pada akhirnya bensin yang memiliki komponen benzene atau lead mengakibatkan peningkatan kadar LDL plasma. Kesimpulan penelitian terdapat pengaruh bensin terhadap kadar LDL pada plasma darah tikus dan beberapa komponen bensin yang berperan, yaitu timbal dan benzena. Scoping Review: Effect of Gasoline on Increasing Blood Plasma LDL Levels in Rats Gasoline consumption from 2000 to 2014 increased along with the increase in the number of motorized vehicles each year. Gasoline harms the environment in the form of pollution and on the health of lung, kidney, skin diseases, and changes in the lipid profile in the form of increased levels of low-density lipoprotein (LDL) which can increase the incidence of coronary and metabolic heart disease. This study aimed to determine the effect of gasoline exposure on LDL levels in human blood plasma starting with a study of experimental animals. The research method used is descriptive with a scoping review procedure by identifying, analyzing, and evaluating scientific papers according to inclusion and exclusion criteria and screening using eligibility criteria. The research results obtained ten articles from the initial number of 10,486 articles found from keywords. Ten PICO-compliant articles (Population: rats; Intervention: gasoline, lead or benzene; Comparison: rats not exposed to gasoline, lead or benzene; Results: LDL levels in blood plasma) showed increased plasma LDL levels in the group of rats exposed to gasoline, lead or benzene control group. This is due to oxidative stress from lead or benzene induction which suppresses antioxidant activity and increases reactive oxygen species in the body, resulting in liver injury, impaired lipoprotein metabolism. In the end, gasoline which has benzene or lead component causes an increase in plasma LDL levels. This study concludes that there is an effect of gasoline on LDL levels in rat blood plasma, and several components of gasoline that play a role, namely lead and benzene.
Protective effect of ethanolic extract of white oyster mushroom on morphological rat sperm damage due to cigarette smoke exposure Santun Bhekti Rahimah; Rio Dananjaya; Ermina Widyastuti; Yudi Feriandi
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art10

Abstract

Background: Cigarettes smokes are a great external source of free radicals. The negative effects of cigarette smoke exposure can be systemic and affect all body systems, including the reproductive. Male rats exposed to cigarette smoke have a risk of oxidative stress and sperm damage. This can be overcome with herbal antioxidants such as white oyster mushrooms (Pleurotus ostreatus).Objective: This study aimed to examine the protective effect of ethanolic extract of white oyster mushroom against damage to sperm morphology of rats exposed to cigarette smoke.Methods: This study is an experimental study using 40 rats which were divided into 5 groups. Group I (normal control), group II (negative control) were only given exposure of cigarette smoke, Grups III, IV and V (treatments groups 1, 2, and 3) were given exposure of cigarette smoke and ethanolic extract a dose of 125, 250, and 500 mg/Kg BW/day for 14 days. On the 15th day, the percentage normal rat sperm were calculated under a 400x magnification microscope.Results: Normal sperm count in group I was 79% ± 0.79, group II was 39% ± 0.55, Grup III, IV and V were 56% ± 0.15, 65% ± 0.54 and 66% ± 0.21.  
Pengaruh Konsumsi Kopi dengan Kualitas Tidur Mahasiswa Fakultas Kedokteran Unisba Wahyu Kijang Ramadhan; Santun Bhekti Rahimah; Ellyi Marliyani
Bandung Conference Series: Medical Science Vol. 2 No. 2 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i2.3726

Abstract

Abstract. The body that was previously tired can be refreshed after sleeping and ready to carry out daily activities. Delayed recovery can prevent organs from functioning optimally and lead to health problems, such as decreased concentration. A good night's sleep is essential for the body to function optimally. Adequate sleep for adults is about 7-8 hours per night, although some people estimate they sleep 5 hours per day. Coffee is one of the most widely available, freely available caffeine-containing beverages and is one of the most consumed beverages after water and is enjoyed by people from all walks of life. times in one day. The habit of drinking coffee in Indonesia is quite high and covers all people from young to old age. This research was conducted using an observational analysis method with a cross sectional approach to determine the effect of coffee consumption on sleep patterns of UNISBA Medical Faculty students in the 2021/2022 Academic Year. Completely answer all the questions contained in the questionnaire that has been given. The sample in this study as many as 93 students, but according to the inclusion criteria as many as 92 people. 2. Most of the Unisba Medical Faculty students for the 2021/2022 academic year have poor sleep quality of up to 85%. Abstrak. Tubuh yang sebelumnya lelah bisa segar kembali setelah tidur dan siap melakukan aktivitas sehari-hari. Pemulihan yang tertunda dapat mencegah organ berfungsi secara optimal dan menyebabkan masalah kesehatan, seperti penurunan konsentrasi. Tidur malam yang baik sangat penting bagi tubuh untuk berfungsi secara optimal. Tidur yang cukup untuk orang dewasa adalah sekitar 7-8 jam per malam, meskipun beberapa orang memperkirakan mereka tidur 5 jam per hari. Kopi adalah salah satu minuman yang mengandung kafein yang paling banyak tersedia, tersedia secara bebas dan merupakan salah satu minuman yang paling banyak dikonsumsi setelah air dan dinikmati oleh orang-orang dari semua lapisan masyarakat. kali pada satu hari. Kebiasaan minum kopi di Indonesia cukup tinggi dan mencakupi semua kalangan dari usia muda sampai usia lanjut. Penelitian ini dilakukan dengan metode analisis observasional dengan pendekatan cross sectional untuk mengetahui pengaruh konsumsi kopi terhadap pola tidur mahasiswa Fakultas Kedokteran UNISBA Tahun Akademik 2021/2022.Penelitian telah dilakukan di mahasiswa Fakultas Kedokteran UNISBA tingkat 4 Tahun Akademik 2021/2022 yang telah bersedia mengikuti penelitian dan menjawab dengan lengkap seluruh pertanyaan yang terdapat pada kuesioner yang telah diberikan. Sampel pada penelitian ini sebanyak 93 orang mahasiswa , akan tetapi yang sesuai dengan kriteria inklusi sebanyak 92 orang. 2. Sebagian besar mahasiswa FK Unisba tahun ajaran 2021/2022 memiliki kualitas tidur kurang baik hingga 85 %.
Semaglutide Oral (Rybelsus) pada Diabetes Melitus Tipe 2 di Ras Asia: Tinjauan Pustaka Ghilda Ainun Nisaa S; Santun Bhekti Rahimah; Yuke Andriane
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.546

Abstract

Abstract. Oral semaglutide is a GLP-1 receptor agonist (GLP-1 RA) which activates the GLP-1 receptor and causes increased control of blood glucose, through increased insulin secretion by pancreatic beta cells, decreased glucagon secretion by pancreatic alpha cells, and decreased emptying rate. stomach. The hormone GLP-1 can have an incretin effect, namely the production of more insulin due to high glucose levels. The effect of increasing in patients with DM(T)2 decreased as active GLP-1 levels also decreased. GLP-1 can also regulate pancreatic beta cell genes by inhibiting their apoptosis, preventing glucolipotoxicity, and enhancing beta cell function. The administration of oral semaglutide drug in DM(T)2 patients with Asian race is also superior because the drug can suppress appetite and make weight loss which will control DM(T)2 in Asian races who have adiposity/fat content and waist circumference is higher. higher than other races, and had a higher decrease in HbA1c levels. Abstrak. Semaglutide oral merupakan GLP-1 receptor agonist (GLP-1 RA) yang akan mengaktifkan reseptor GLP-1 dan menyebabkan peningkatan kontrol dari glukosa darah, melalui peningkatan sekresi insulin oleh sel beta pankreas, penurunan sekresi glukagon oleh sel alfa pankreas, dan penurunan laju pengosongan lambung. Hormon GLP-1 dapat memberikan efek incretin, yaitu pengeluaran insulin yang lebih banyak karena kadar glukosa yang tinggi. Efek incretin pada pasien DM(T)2 mengalami penurunan seiring dengan kadar GLP-1 aktif yang juga menurun. GLP-1 juga dapat mengatur gen sel beta pankreas dengan menghambat apoptosisnya, mencegah glukolipotoksisitas, dan meningkatkan fungsi sel beta. Pemberian obat semaglutide oral pada pasien DM(T)2 dengan ras Asia juga lebih unggul karena obat tersebut dapat menekan nafsu makan dan membuat penurunan berat badan yang akan mengendalikan DM(T)2 pada ras Asia yang memiliki adipositas/ kandungan lemak dan lingkar pinggang lebih tinggi dibandingkan ras lain, serta memiliki penurunan kadar HbA1c yang lebih tinggi.
Scoping Review: Pengaruh Pemberian Kurma (Phoenix Dactylifera) terhadap Kadar Glukosa Darah Penderita Diabetes Melitus Tipe II Andika Agung Pambudi; Santun Bhekti Rahimah; Susan Fitriyana Nugraha
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.1125

Abstract

Abstract. Diabetes mellitus (DM) is a metabolic disease characterized by impaired carbohydrate, protein and fat metabolism. The cause of type 2 diabetes mellitus is the occurrence of insulin resistance and impaired function of pancreatic cells. Many alternative treatments are believed to be able to control blood glucose levels, one of which is dates. Dates (Phoenix dactylifera) contain procyanidin, phenolic, p-coumaric, ferulic acid, synapic acid and sinnamic acid derivatives which are expected to act as interventions in controlling blood glucose levels in patients with type 2 diabetes. This study aims to determine the effect of dates (Phoenix dactylifera)) on blood glucose levels of people with type 2 diabetes mellitus. This research is astudy Scoping Review, by searching for articles from thedatabases Google Scholar, ProQuest, Springer Link, and Science Direct. Articles that meet the inclusion criteria are 246 articles with the results of the feasibility test based on PICOS and a critical study using CASP, the remaining 2 articles. The results of the two articles reviewed stated that the administration of dates on blood sugar levels in type 2 DM patients was not significant. The conclusion of this study is that dates have no effect on lowering blood glucose levels in both patients with type 2 Diabetes Mellitus and patients without the disease. Abstrak. Diabetes melitus (DM) merupakan penyakit metabolik yang ditandai dengan gangguan metabolisme karbohidrat, protein dan lemak. Penyebab diabetes melitus tipe 2 adalah terjadinya resistensi insulin dan gangguan fungsi pada sel β pankreas. Banyak pengobatan alternatif diyakini dapat mengontrol kadar glukosa darah, salah satunya adalah kurma. Kurma (Phoenix dactylifera) memiliki kandungan procyanidin, fenolik, p-coumaric, asam ferulic, asam sinapik dan derivate asam sinnamic yang diharapkan dapat berperan sebagai intervensi dalam mengontrol kadar glukosa darah penderita DM tipe 2. Penelitian ini bertujuan untuk mengetahui pengaruh kurma (Phoenix dactylifera) terhadap kadar glukosa darah penderita diabetes melitus tipe 2. Penelitian ini merupakan penelitian Scoping Review, dengan mencari artikel dari database Google Scholar, ProQuest, Springer Link, dan Science Direct. Artikel yang sesuai kriteria inklusi sebanyak 246 artikel dengan hasil uji kelayakan berdasar PICOS dan telaah kritis menggunakan CASP yang tersisa sebanyak 2 artikel. Hasil penelitian dari dua artikel yang diulas menyatakan bahwa pemberian kurma terhadap kadar gula darah pada pasien DM tipe 2 ditemukan hasil yang tidak signifikan. Kesimpulan dari penelitian ini adalah, kurma tidak memiliki efek dalam menurunkan kadar glukosa darah baik pada pasien dengan penyakit Diabetes Mellitus tipe 2 maupun pasien yang tidak memiliki penyakit tersebut.
Stres Mahasiswa Fakultas Kedokteran Selama Masa Pembelajaran Daring: Kajian Pustaka Mohammad Dannys Ares; Santun Bhekti Rahimah; Uci Ary Lantika
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.1794

Abstract

Abstract. The world is currently being hit by an outbreak of coronavirus disease or Covid-19. This causes almost all normal activities of society to change in all aspects of life. The rapid spread of the Covid-19 outbreak has forced every country to act quickly and appropriately to reduce the number of spreads. One of the efforts of the Indonesian government is to make changes to the online learning process policy for all levels of education. The high academic burden and demands coupled with this pandemic situation puts medical students at greater risk for physical and mental health problems. The learning process, tight schedule and coupled with a large task load and various obstacles encountered in the online learning process trigger stress so that it has the potential to cause other impacts that can affect health and academic performance. Abstrak. Dunia saat ini sedang dilanda wabah coronavirus disease (Covid-19) dan menyebabkan hampir seluruh aktivitas normal masyarakat berubah di seluruh aspek kehidupan. Penyebaran wabah Covid-19 yang sangat cepat menyebabkan setiap negara harus bertindak cepat dan tepat untuk menekan angka penyebaran. Salah satu upaya pemerintah Indonesia adalah membuat kebijakan perubahan proses pembelajaran yang dilakukan secara daring untuk seluruh tingkat pendidikan. Beban dan tuntutan akademik yang tinggi ditambah dengan situasi pandemi ini membuat mahasiswa kedokteran memiliki risiko yang lebih besar terhadap masalah kesehatan fisik dan mental. Proses pembelajaran, jadwal yang padat dan ditambah dengan beban tugas yang banyak serta berbagai kendala yang ditemui dalam proses pembelajaran daring ini memicu terjadinya stres sehingga berpotensi menimbulkan dampak lain yang dapat mempengaruhi kesehatan dan kinerja akademis.
Gambaran Derajat Stres Kerja dan Kejadian Kecelakaan Kerja pada Komunitas Ojek Online di Kota Bandung Kifa Fauziyyah Kuswardian; Santun Bhekti Rahimah; R. Kince Sakinah
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.5865

Abstract

Abstract. Stress at work can affect employees physiologically, psychologically, and behaviorally. Symptoms of stress at work can cause increased heart rate, increased blood pressure, digestive system disorders and increased secretion of adrenaline and non-adrenaline, prolonged sadness, difficulty concentrating, pessimism, always feeling like a failure, always being afraid, uncomfortable sleep, easy cry, feeling lonely, feeling that people are unfriendly, unhappy, having less dialogue and being insecure, argumentative, creating trouble at work, using alcohol and drugs, smoking, and neglecting responsibilities. This research aims to find out the picture of the degree of stress and the incidence of work accidents on Online Taxis in the City of Bandung. The research method is descriptive with a cross sectional design. The sample of this research is the KOMPAS Online Taxi Community in the City of Bandung. The KOMPAS Online Taxi Community in the City of Bandung totals 70 people, with total sampling. The research variables are the degree of stress and the incidence of work accidents. The data analysis used was univariate. The results of the research show that the degree of stress of the KOMPAS Online Taxi Community is mostly moderate (90%) and as many as 71.4% of the online taxi community have experienced work accidents. It is recommended that drivers do stress management to prevent an increase in stress on drivers. Abstrak. Stres di tempat kerja dapat mempengaruhi pekerja secara fisiologis, psikologis, serta perilaku. Gejala stres di tempat kerja dapat menyebabkan adanya peningkatan denyut jantung, peningkatan tekanan darah, kesedihan berkepanjangan, sulit berkonsentrasi, pesimisme, selalu merasa gagal, selalu takut, tidur tidak nyaman, merasa orang tidak ramah, tidak senang, berdialog lebih sedikit dan tidak aman, argumentatif, menimbulkan terbentuknya musibah di tempat kerja, menggunakan alkohol dan narkoba, merokok, serta mengabaikan tanggung jawab. Penelitian ini bertujuan untuk mengetahui gambaran derajat stres dan kejadian kecelakaan kerja pada Ojek Online di Kota Bandung Metode penelitian adalah analitik dengan rancangan cross sectional. Sampel penelitian ini adalah Komunitas Ojek Online KOMPAS di Kota Bandung. Penelitian ini menggunakan total population sampling yang berjumlah 70 orangVariabel penelitian adalah derajat stres dan kejadian kecelakaan kerja. Analisis data yang digunakan adalah univariat. Hasil penelitian menunjukkan bahwa derajat stres Komunitas Ojek Online KOMPAS sebanyak 90% mengalami stress sedang dan sebanyak 71.4% komunitas ojek online pernah mengalami kecelakaan kerja. Komunitas ojek online diharapkan dapat melakukan manajemen stres yang baik, serta dapat mencegah adanya dampak negatif lain akibat stress seperti halnya peningkatan kecelakan kerja.
Scoping Review: Hubungan Konsumsi Kafein Dengan Kejadian Nyeri Kepala Pada Orang Dewasa Chagieansyah Hadie Widjaya; Santun Bhekti Rahimah; Eka Nurhayati
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6660

Abstract

Abstract. Caffeine is a substance that can function as a stimulant in the central nervous system. Caffeine has good benefits in the body because it can modify and regulate neurotransmitters, as well as help bring out hidden potential in the body. This research aims to analyze the relationship between caffeine consumption and the occurrence of headaches in adults. The method used is a Scoping Review which consists of stages, namely: conducting a focusing review with the PICOS framework (Population, Intervening, Comparison, Outcome and Study), conducting literature searching using 3 databases, namely ScienceDirect, SpringerLink, Pubmed. Selecting relevant studies using inclusion and exclusion criteria; perform JBI critical appraisal to evaluate the quality of the literature, perform data extraction, analyze and report the results. The compilation procedure using the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) method was used to describe the literature search flow. The results were obtained as many as 8 international articles published in the period of 2013-2021, in all articles found the effect of caffeine on headaches. The conclusion that caffeine is related to migraine headache, Post Dural Puncture Headache (PDPH), and episodic-tension and caffeine can affect cognitive and physical performance. For the need to improve cognitive and physical performance, in addition to caffeine, herbal supplements can also be used. Abstrak. Kafein merupakan zat yang dapat berfungsi sebagai stimulan pada sistem saraf pusat. Kafein mempunyai manfaat baik dalam tubuh karena dapat memodifikasi dan mengatur neurotransmitter, serta membantu memunculkan potensi tersembunyi dalam tubuh. Metode yang digunakan adalah adalah Scoping Review yang terdiri dari tahapan-tahapan, yaitu: melakukan fokusing review dengan framework PICOS (Population, Intervening, Comparison, Outcome dan Study), melakukan literature searching menggunakan 3 database, yaitu ScienceDirect, SpringerLink, Pubmed. Menyeleksi studi yang relevan menggunakan kriteria inklusi dan ekslusi; melakukan JBI critical appraisal untuk menilai kualitas literatur, melakukan data ekstraksi, menganalisis dan melaporkan hasil. Prosedur penyusunan menggunakan metode Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) digunakan untuk menggambarkan alur pencarian literatur. Hasil penelitian diperoleh sebanyak 8 artikel internasional yang dipublikasikan pada kurun waktu tahun 2013-2021, pada semua artikel ditemukan artikelnya ditemukan pengaruh kafein terhadap sakit kepala. Simpulan bahwa kafein berhubungan terhadap sakit kepala migrain, Post Dural Puncture Headache (PDPH), dan episodic-tension dan kafein dapat mempengaruhi performa kognitif dan fisik. Peningkatan performa kognitif dan fisik, selain kafein, dapat digunakan pula suplemen campuran tumbuh-tumbuhan.
Efektivitas Antioksidan Terhadap Pencegahan Katarak Salsabila Roudotul Farihah; Santun Bhekti Rahimah; Raden Ganang Ibnusantosa
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.5939

Abstract

Abstract. Cataract is a degenerative process, in which the lens of the eye becomes cloudy, which can lead to reduced vision and blindness. The cloudiness of the lens is caused by a biochemical reaction that causes protein coagulation in the lens. Antioxidants can be used as an alternative treatment to delay and/or prevent disease progression and are believed to be able to prevent cataracts by neutralizing free radicals. This research aims to find out the effect of antioxidant administration on cataract sufferers in the elderly. The method used is the Scoping Review technique. The research sample is in the form of articles, which are taken from 3 databases namely SpringerLink, Science Direct and PubMed. The steps taken are selecting relevant articles using inclusion and exclusion criteria. The results of the articles obtained as a whole were 15,960 articles, and then on the inclusion criteria screening, 422 articles were obtained. There are 5 duplicate articles were deleted. In the process of screening for discrepancies in article titles and abstracts based on PICOS, critical appraisal with CASP and JBI obtained 3 articles, then data extraction and results reporting were carried out. The preparation procedure using the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) method was used to describe the literature search flow. The results obtained were published in the period 2012-2022. The results showed that there was an effect of consumption of vitamin C, vitamin E, beta-carotene, and B vitamins on reducing the incidence of age-related cataracts and consumption of vitamin E and selenium supplements did not have a significant effect on the incidence of age-related cataracts. Keywords: Antioxidant, Cataract, Elderly Abstrak. Katarak adalah proses degeneratif, di mana lensa mata menjadi keruh sehingga dapat menyebabkan menurunnya kemampuan pengelihatan hingga kebutaan. Kekeruhan pada lensa tersebut disebabkan terjadinya reaksi biokimia yang menyebabkan adanya koagulasi protein di dalam lensa. Antioksidan dapat digunakan sebagai pengobatan alternatif untuk menunda dan/atau mencegah perkembangan penyakit dan dipercaya mampu untuk mencegah katarak dengan menjadi penetralisir radikal bebas. Penelitian bertujuan untuk mengeksplorasi artikel yang meneliti efektivitas antioksidan terhadap pencegahan katarak pada lansia. Metode yang digunakan adalah scoping review, sampel penelitian berupa artikel-artikel yang diambil dari 3 database yaitu SpringerLink, Science Direct dan Pubmed. Artikel yang relevan dipilih menggunakan kriteria inklusi dan ekslusi. Hasil artikel yang didapatkan secara keseluruhan yaitu 15.960 selanjutnya skrining kriteria inklusi didapatkan 422 artikel, menghapus 5 artikel duplikasi, skrining ketidaksesuaian judul artikel dan abstrak berdasarkan PICOS, critical appraisal dengan CASP dan JBI didapatkan 3 artikel, melakukan ekstraksi data, dan melaporkan hasil. Prosedur penyusunan menggunakan metode Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) digunakan untuk menggambarkan alur pencarian literature. Hasil yang diperoleh dipublikasikan pada kurun waktu tahun 2012-2022. Hasil penelitian menunjukkan adanya pengaruh konsumsi vitamin C, vitamin E, beta-karoten, dan vitamin B terhadap penurunan insiden katarak terakit usia dan konsumsi suplemen vitamin E dan selenium tidak memberikan efek yang signifikan terhadap insiden katarak terkait usia. Kata Kunci: Antioksidan, Katarak, Lansia
Co-Authors Andika Agung Pambudi Anna Fatwa Aistu Arief Budi Yulianti Asep Saefulloh Chagieansyah Hadie Widjaya Dede Setiapriagung Dinarita Sari Nurhalimah Eka Nurhayati Ellyi Marliyani Endang Suherian Ermina Widyastuti Ermina Widyastuti Fajar Awalia Yulianto Fenda Khafidhotenty Ghilda Ainun Nisaa S Helga Marwa Afifah Helga Marwa Afifah, Helga Marwa Herri S. Sastramihardja Herry S. Sastramihardja Ismet Muchtar Nur Kifa Fauziyyah Kuswardian Maya Tejasari Meike Rachmawati Meta Maulida Damayanti Mia Kusmiati MIranti Kania Dewi Miranti Kania Dewi Mohammad Dannys Ares Muhammad Alief Abdul ‘Aziiz Muhammad Faridza Muhammad Ilham Halim Nabila Tarlita Luthfiyah Nanan Sekarwana Nugraha Sutadipura Pradipto Atyanto Wibowo R. Kince Sakinah Raden Ganang Ibnusantosa Rahma Ratu Halima Rio Dananjaya Salsabila Roudotul Farihah Santoso, Shenny Dianathasari Siti Annisa Devi Trusda Susan Fitriyana Trully Detty Sitorus Uci Ary Lantika Wahyu Kijang Ramadhan Winni Maharani Yola Noveraz Nasa Yudi Feriandi Yuke Andriane Yuke Andriane Yuktiana Kharisma Yuniarti