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All Journal Medical Journal of Indonesia Jurnal Respirologi Indonesia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Respiratory Science eJournal Kedokteran Indonesia

Menaldi Rasmin

Department Of Pulmonology And Respiratory Medicine Faculty Of Medicine, Universitas Indonesia

Author-ID : 358082

Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Asthma prevalence among high school students in East Jakarta, 2001, based on ISAAC questionnaire Yunus, Faisal; Antaria, Ratnawati; Rasmin, Menaldi; Mangunnegoro, Hadiarto; Jusuf, Anwar; Bachtiar, Adang
Medical Journal of Indonesia Vol 12, No 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

The aim of this study was to assess asthma prevalence in children between 13-14 years of age in East Jakarta. This study is a cross sectional study which surveyed 2234 high school students between the ages of 13 and 14 years in East Jakarta in 2001 using the ISAAC questionnaire. Bronchial challenge test was applied by using methacholine substance to 186 students. Reports based on the ISAAC questionnaire indicate that 7.2% of teenage have had wheezing experience, 4.1% have wheezing within the last 12 months, 1.8% have ever suffered severe asthma attack within the last 12 months, 3.3% have suffered wheezing after exercise, and 6.3% have got night cough while they were not suffering from cold. Prevalence of atopy diseases such as rhinitis and eczema were 14.2% and 3.9%, meanwhile rhinitis and eczema prevalence within the last 12 months according to this study were 10.6% and 2.9% respectively. Statistically, there is a significant correlation between wheezing symptom and atopy (p < 0.05). From indepth questionnaire, a significant value of kappa 0.84 related with wheezing within the last 12 months was found. Bronchial challenge test results indicate that sensitivity was 90%, specificity 83.58%, positive predictive value 68.12% and negative predictive value was 95.73%. Asthma prevalence in East Jakarta at 2001 based on ISAAC questionnaire was 8.9%, and cumulative prevalence 11.5%. The ISAAC questionnaire can be used to study asthma prevalence in children at multicenter in Indonesia.Â (Med J Indones 2003; 12: 178-86)Keywords:Â bronchial challenge, high school student, ISAAC questionnaire, East Jakarta, asthma prevalence

Effectiveness of intravenous clarithromycin followed by oral clarithromycin in acute exacerbation of asthma with respiratory tract infection Wiyono, Wiwien H.; Febriana, Risa; Yunus, Faisal; Nawas, Arifin; Rasmin, Menaldi
Medical Journal of Indonesia Vol 16, No 1 (2007): January-March
Publisher : Faculty of Medicine Universitas Indonesia

In addition to its antimicrobial activity, macrolides have an immunomodulatory effect that may be beneficial to patients with asthma. This quasi-experimental study aimed to determine the effect of intravenous clarithromycin followed by oral administration in 37 patients with acute exacerbations asthma caused by respiratory tract infection during January - December 2005. Patients with mild to moderate exacerbations of asthma with respiratory tract infection meeting the inclusion and exclusion criteria were given intravenous clarithromycin 2 x 500 mg/day for not more than 5 days and followed by oral clarithromycin 2 x 500 mg/day for 7 days. Outcome variables were improvement of clinical symptoms according to the asthma exacerbation score and peak expiratory flow rate (PEFR). After 10 days, treatment resulted significant improvement in total asthma exacerbation score and morning PEFR in 35 patients enrolled this project. Based on clinical improvement and laboratory findings, the number of days required for intravenous clarithromycin was less then 3 days for 21 subjects, 3-5 days in 14 subjects. The most common causative pathogens were S. Î²-haemolyticus and Streptococcus sp. It was concluded that clarithromycin improved clinical symptoms and PEFR in exacerbation of asthma caused by respiratory tract infection. (Med J Indones 2007; 16:7-13) Keywords: Claritromycin, asthma exacerbation, respiratory tract infection

Failure of Breathing in Heavy Preeklampsia With Peripartum Cardiomiopathy Desilia Atikawati; Diyan Ekawati; Pusparini Kusumajati; Prasenohadi Prasenohadi; Menaldi Rasmin
Jurnal Respirologi Indonesia Vol 37, No 4 (2017)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Physiological alterations during pregnancy generate higher risk of pulmonary edema and acute respiratory failure. Respiratory failure occurs in 0.2% pregnancy, particularly in postpartum period. Respiratory failure can be developed by specific conditions related to pregnancy, such as preeclampsia and peripartum cardiomyopathy. We present the case of 34-year-old female, with 36 weeks of pregnancy, that came with shortness of breath since an hour before admitted. Patient also had vaginal discharge in the last two hours before admitted. Fetal movement was active. Shortness of breath was accompanied with cough. Physical examination revealed hypertension (160/110 mmHg) and rales on both lungs. Blood gas analysis showed severe hypoxemia. Patient were intubated and underwent C-section afterwards. Chest x-ray showed heart enlargement. Echocardiography result showed fraction ejection 25%, global hypokinetic, mild mitral and tricuspid regurgitation, with conclusion of peripartum cardiomyopathy. This case illustrates respiratory failure in severe preeclampsia and peripartum cardiomyopathy. This condition leads to acute pulmonary edema that impairs ventilation/perfusion process. Mechanical ventilation can assure adequate oxygen delivery. Non-invasive ventilation (NIV) is well suited to short-term ventilatory support, and avoids the potential complications of endotracheal intubation and the associated sedation. (J Respir Indo. 2017; 37(4): 325-36)

Hypoxemia Event and Related Factor on Diagnostic Bronchoscopy for Lung Tumor Case Andre Prawira Putra; Menaldi Rasmin; Wahju Aniwidyaningsih
Jurnal Respirologi Indonesia Vol 40, No 2 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i1.93

Background: Bronchoscopy is a commonly medical procedure perfomed for diagnose lung tumor cases. Hypoxemia often appear as complication related diagnostic bronchoscopy. Therefore, there is a need of research data to knowing related factors and clinical consequences may occur ahead. Methods: Design of this study is cross sectional with suspicion lung malignancy population who undergoing diagnostic bronchoscopy from January until april 2019 at National Respiratory Center Persahabatan General Hospital Jakarta. Total 195 consecutive patients participated dan observed for oxygen saturation in premedication, during and post-bronchoscopy. Hypoxemia was defined as a desaturation

Respiratory Failure in Pneumonia with Diabetic Ketoacidosis (DKA) Novita Maulidiyah; Sri Indah Indriani; Prasenohadi Prasenohadi; Menaldi Rasmin
Jurnal Respirologi Indonesia Vol 38, No 1 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i1.140

The annual incidence rate of KAD is estimated to be between 4.6 and 8 per 1000 patients with diabetes. Based on the results of the physical examination, the patient was diagnosed as pneumonia with KAD. The mortality rate for community pneumonia on outpatients was 2%, inpatients was 5-20%, more so in patients in intensive care that was more than 50%. The problem in the patient is pneumonia. Resulting in pulmonary dysfunction which causes overload. Infections that can increase morbidity and mortality may be associated with Streptococcus infection (group B, S, pneumonia), Legionella and viral infections (influenza). The most common infections are pneumonia and urinary tract infections which account for between 30% and 50% of cases. Therefore, the choice of empiric antimicrobial therapy in diabetic patients with evidence of staphylococcal pneumonia (consistent with sputum smear results or associated soft tissue infection) should be guided by the prevalence of MRSA in the associated institutions. Respiratory failure is a complication of KAD and increases the mortality rate. and morbidity. Based on the high nasal carriage rate, there is an increased risk of staphylococcal pneumonia infection in diabetic patients. Community pneumonia is acute inflammation due to infection of the lung parenchyma acquired in the community. (J Respir Indo 2018; 38(1): 57-63)

Mechanical Ventilation in Non Lung-Post Surgery Patients Ika Yunita Sari; Sri Wening Pamungkasningsih; Menaldi Rasmin
Jurnal Respirologi Indonesia Vol 38, No 3 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

A case of a 41-year-old man, with a lump in his left abdomen since 5 months before admission to the hospital. In the last 2 weeks the patient complained of reddish urine and pain during urination. The diagnosis of the patient is a left kidney tumor, has performed nephrectomy and splenectomy surgery. Postoperative complications include sepsis, anemia and hypoalbuminemia. Sepsis in these patients is caused by colonic perforation leading to intra-abdominal infection. These complications cause patients to get treatment in the intensive care unit longer by using a ventilator for four days.

Breath Failure in Obesity Wirya Sastra Amran; Putri Suci; Nina Aspiah; Menaldi Rasmin; Prasenohadi Prasenohadi; Agus Dwi Susanto
Jurnal Respirologi Indonesia Vol 38, No 2 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i2.167

Based on calculations of over one million people in the world weighing excessively or known as obesity with body mass index (IMT) 25 kg / m2 or more. Obesity is the cause of morbidity, as is the case in the population of the United States an estimated 400,000 deaths caused due to obesity. Obesity especially abdominal obesity is a significant risk factor for cardiovascular diseases, type 2 diabetes, rheumatoid arthritis and cancer. The relationship between obesity and chronic respiratory illness began to increase and began to be recognized. The World Health Organization (WHO) predicts about 10% of the global population will be obese by 2015. (J Respir Indo 2018; 38(2): 123-33)

Multiple Possible Causes Of Dyspnea In An Unusual Pickwickian Syndrome On Covid-19 Pandemic: A Case Study Steven Jonathan; Menaldi Rasmin
Respiratory Science Vol. 2 No. 2 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i2.44

Introduction: Pickwickian Syndrome (PS) or obesity hypoventilation syndrome (OHS) is a diagnosis of exclusion with features of obesity, sleep disordered breathing, and chronic daytime hypercapnia. Patients with PS could present into general OSA or respiratory failure. We are presenting an unusual case of PS with acute respiratory failure resulting in organ failure and mortality. Case report: A 41-year-old male was admitted to hospital due to shortness of breath. He had a trouble sleeping; frequently awoke as the breathing briefly stopped and gasping. There were history of diabetes melitus (DM) and hypertension for >10 years, smoking with moderate Brinkman Index. Patient appeared to have somnolence, tachypnea, hypoxemia, morbid obesity. We assessed him as PS, bronchopneumonia, respiratory failure, pulmonary edema, hypertensive heart disease (HHD), DM, acute on CKD. We managed him with pharmacotherapy, oxygen (BiPAP), and hemodialysis. After transferred from ICU to regular ward, patient was suddenly apneic and CPR was performed; ended in mortality. Discussion: This unusual case (malignant OHS) was a subgroup among OHS with greater morbidity and multiorgan system dysfunction. There were multiple causes of dyspnea on our patient which concluded to a death case. There are three modalities of management in stable PS: positive airway pressure (PAP), weight reduction, and pharmacotherapy. The management of respiratory failure in PS mainly involved oxygen therapy in positive pressure. Conclusion: There were multiple causes of dyspnea in this patient. Optimal management of patient ought to treat not only the PS but also all the comorbidities.

Preoperative Assessment Prior to Lung Resection: How to Eliminate the Risk Dian Megawati; Menaldi Rasmin; Budhi Antariksa; Faisal Yunus
Respiratory Science Vol. 2 No. 3 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i3.48

Lung resection is part of the treatment of various lung diseases, both malignancy and infection. Although it has great benefits, lung resection can result in a variety of functional disorders that can affect the whole cardiopulmonary system. The mortality of these procedures is 2-4% in segmentectomy and 6-8% in lobectomy, while the mortality of pneumonectomy in the world is 11%. Good preoperative assessment of patients has been reported to have reduced mortality and morbidity after lung resection. Things that need to be considered to assess preoperative eligibility include age, lung function, cardiovascular fitness, nutrition, and performance status. The preoperative pulmonary tolerance assessment is divided into three stages: the first stage is the assessment of lung function and blood gas analysis, the second stage is to assess postoperative prediction of pulmonary function, and the third stage is to assess the maximum oxygen consumption per minute by doing a cardiopulmonary exercise test. Patients who have a good tolerance for lung resection are patients who have predictive postoperative force expiration volume one second (ppoFEV1) values more than 40%, predictive postoperative diffusion capacity of the lung for carbon monoxide (ppoDLCO) more than 50%, and maximum oxygen consumption (VO2 max) more than 15ml/kg/min.

Pengetahuan dan Perilaku Mahasiswa Tingkat Akhir FKUI terhadap COVID-19 pada Tahun Ajaran 2020/2021 Fanny Michelle; Menaldi Rasmin
eJournal Kedokteran Indonesia Vol 9, No. 3 - Desember 2021
Publisher : Faculty of Medicine Universitas Indonesia

COVID-19 adalah penyakit pernapasan akibat SARS-CoV-2 yang merupakan pandemi dunia. Dalam menghadapi COVID-19, diperlukan pengetahuan dan perilaku pencegahan yang baik di masyarakat. Sebagai calon dokter, mahasiswa kedokteran tingkat akhir perlu memiliki pengetahuan baik agar dapat mengedukasi masyarakat serta perilaku baik agar dapat melindungi diri dan menjadi contoh bagi masyarakat. Tujuan penelitian ini adalah mengetahui tingkat pengetahuan dan perilaku, hubungan pengetahuan dengan perilaku, serta hubungan faktor sosiodemografi dan sumber informasi dengan pengetahuan dan perilaku terhadap COVID-19 pada mahasiswa tingkat akhir FKUI tahun ajaran 2020/2021. Penelitian ini menggunakan desain potong lintang dengan sampel seluruh mahasiswa tingkat akhir FKUI. Instrumen yang digunakan adalah kuesioner Knowledge, Attitude and Practice toward the Novel Coronavirus (COVID-19) yang disebarkan secara daring. Data dianalisis dengan uji chi-square dan uji Fisher. Tingkat pengetahuan subjek yang tergolong sangat baik adalah 70%. Tingkat perilaku subjek mayoritas tergolong cukup yakni 65,5%. Tidak terdapat hubungan antara pengetahuan dengan perilaku (p=0,403), namun terdapat hubungan antara jenis kelamin dan sumber informasi utama dengan pengetahuan (p=0,011 dan 0,005). Pengetahuan mahasiswa kedokteran tingkat akhir mengenai COVID-19 tergolong sangat baik, namun perilaku tergolong cukup. Untuk meningkatkan perilaku, diperlukan intervensi langsung secara struktural dari universitas, tidak hanya dengan peningkatan pengetahuan.

Co-Authors Adang Bachtiar Agus Dwi Susanto Agus Dwi Susanto Andre Prawira Putra Anggie Indari Anwar Jusuf Ari Fahrial Syam Arifin Nawas Budhi Antariksa Desilia Atikawati Dewi Friska Dian Megawati Diyan Ekawati Elisna Syahrudin Erlina Burhan Ernita Akmal Faisal Yunus Faisal Yunus Falah Kartikawati Fanny Michelle Feni Fitriani Taufik Filemon Suryawan Handjaja Hadiarto Mangunnegoro Hilma Nur Faiza Ika Yunita Sari Kemal Akbar Suryoadji Kevin Aristyo Nani Cahyani Sudarsono Neny Husnaini Zain Nina Aspiah Novita Maulidiyah Prasenohadi Prasenohadi Prasenohadi Prasenohadi Pusparini Kusumajati Putri Suci Ratnawati Antaria Risa Febriana Rita Rogayah Sakinasha Siva Utami Siti Chandra Widjanantie Sri Indah Indriani Sri Wening Pamungkasningsih Steven Jonathan Thariq Emyl Taufik Hasibuan Tri Apriliawan Bendarto Rahardjo Vina Fiqria Wahju Aniwidyaningsih Widhy Yudistira Nalapraya Wirya Sastra Amran Wiwien H. Wiyono Zuswayudha Sjamsu

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