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All Journal Akmenika : Jurnal Akuntansi dan Manajemen Medical Journal of Indonesia AKMENIKA
Endang Ratnaningsih
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Economics, Econometrics & Finance Medicine & Pharmacology Other

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A randomized comparative trial of first-dose response to Angiotensin- Converting Enzyme Perindopril and Captopril in Indonesian heart failure patients Makmun, Lukman H.; Abdurachman, Nurhay; Alwi, Idrus; Afandi, Dedi; Siswanto, Bambang B.; Andriantoro, Hananto; Ratnaningsih, Endang; Utomo, Hari
Medical Journal of Indonesia Vol 11, No 1 (2002): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (548.88 KB) | DOI: 10.13181/mji.v11i1.45

Abstract

Several large placebo-controlled trials have confirmed that angiotensin converting enzyme (ACE) inhibitors significantly reduce mortality aid morbidity in all functional grades of congestive heart failure (CHF), nevertheless only a proportion of patients who may benefit from treatment are priscribed an ACE inhibitor. One of the perceived difficulties is the occurrence of first-dose hypotension in susceptible patients. A double-blind, randomised, single-dose therapy, parallel-group study was conducted with the aim to compare the first-dose responses to low dose ACE inhibitors captopril and perindopril in patients with stable chronic heart failure. Seventy patients (New York Heart Association class I-IV) were included. Blood pressure was recorded every 15 minutes 2 hours before starting treatment. The mean of these readings was taken as the baseline blood pressure. Patients were randomised to receive a single-dose of captopril 6.25 mg or perindopril 2 mg. After taking the drug, blood pressure was monitored every 15 minutes for 2 hours, every 30 minutes during 5 hours then hourly after 2 hours. The maximum mean arterial pressure fall from baseline of perindopril was 0.85 mmHg compared to captopril 4.60 mmHg. The maximum mean systolic fall from baseline of perindopril was 3 31 mmHg compared to captopril 6.76 mmHg while the maximum mean diastolic fall from baseline of perindopril was 1.08 mmHg compared to captopril 2.63 mmHg. The hypotensive effect of the captopril group started soon after dosing and reached its maximum after 1 to 2 hours while perindopril showed slight reduction of systolic after 1 hour and slight reduction of diastolic after 4 hours. Compared to captopril, perindopril seemed to be less likely to cause first-dose hypotension in patients with heart failure. (Med J Indones 2002; 11: 19-23)Keywords: first dose hypotension, perindopril, captopril, chronic heart failure
Pengaruh Viral Marketing terhadap Brand Equity pada Pengguna Smartphone Samsung di Yogyakarta Ratnaningsih, Endang
Akmenika Vol 13, No 1 (2016): AKMENIKA
Publisher : Universitas PGRI Yogyakarta

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Abstract

This research conducted to analyze the impact of viral marketing to brand equity of Samsung smartphone. The Samsung smartphone was dominating the Indonesian smartphone's market in 2015, since the online marketing and the viral marketing became the buzz word for business in the last ten years. This study focused to anempirical study that was conducted to 100 undergraduate students in Yogyakarta.The data were collected from consumers of Samsung smartphone and was tested forits construct validity and reliability and regression was applied to test the hypotheses. This findings indicated that viral marketing had a significant and positive influence to brand equity of Samsung smartphone, and showed that viral marketing had a huge potential distribution channel to marketing the product.
Pengaruh Viral Marketing Terhadap Brand Equity Pada Pengguna Smartphone Samsung Di Yogyakarta Ratnaningsih, Endang
Akmenika: Jurnal Akuntansi dan Manajemen Vol 13, No 1 (2016): AKMENIKA
Publisher : Universitas PGRI Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31316/akmenika.v13i1.1226

Abstract

This research conducted to analyze the impact of viral marketing to brand equity of Samsung smartphone. The Samsung smartphone was dominating the Indonesian smartphone’s market in 2015, since the online marketing and the viral marketing became the buzz word for business in the last ten years. This study focused to an empirical study that was conducted to 100 undergraduate students in Yogyakarta. The data were collected from consumers of Samsung smartphone and was tested for its construct validity and reliability and regression was applied to test the hypotheses. This findings indicated that viral marketing had a significant and positive influence to brand equity of Samsung smartphone, and showed that viral merketing had a huge potential distribution channel to marketing the product.
Co-Authors Bambang B. Siswanto Dedi Afandi Hananto Andriantoro Hari Utomo Idrus Alwi Lukman H. Makmun Nurhay Abdurachman